Trust and autonomy in end of life: considering the interrelation between patients and their relatives.

abstract：PURPOSE OF REVIEW:To summarize developments in the management of brain metastases over the past decade. RECENT FINDINGS:A few randomized trials have been published during the past decade examining the use of whole brain radiotherapy (WBRT) and radiosurgery (SRS) boost versus WBRT alone. Other recent trials have been p...

journal_title：Current opinion in supportive and palliative care

authors： Tsao MN,Khuntia D,Mehta MP

更新日期：2012-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize current knowledge on promising immunotherapeutic agents and to provide a brief outline of current use of immunotherapeutic agents in patients with locally advanced or metastatic renal cell carcinoma (RCC). RECENT FINDINGS:Immunotherapy with mAbs directed against programed death cell prot...

journal_title：Current opinion in supportive and palliative care

authors： Nazzani S,Bazinet A,Karakiewicz PI

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Myofascial pain syndrome is a chronic pain condition characterized by the presence of myofascial trigger point, a hyperirritable painful spot involving a limited number of muscle fibers. The literature suggest that myofascial trigger points should be considered peripheral pain generators and this crit...

journal_title：Current opinion in supportive and palliative care

authors： Barbero M,Schneebeli A,Koetsier E,Maino P

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the mechanisms of muscle wasting and how inhibiting myostatin signaling affects them. RECENT FINDINGS:Myostatin signaling is critical for the understanding of the pathogenesis of muscle wasting as blocking signaling mitigates muscle losses in rodent models of catabolic diseases includin...

journal_title：Current opinion in supportive and palliative care

authors： Han HQ,Mitch WE

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cancer cachexia remains understudied and there are no standard treatments available despite the publication of an international consensus definition and the completion of several large phase III intervention trials in the past 6 years. In September 2015, The University of Rochester Cancer Center NCORP...

journal_title：Current opinion in supportive and palliative care

authors： Dunne RF,Mustian KM,Garcia JM,Dale W,Hayward R,Roussel B,Buschmann MM,Caan BJ,Cole CL,Fleming FJ,Chakkalakal JV,Linehan DC,Hezel AF,Mohile SG

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The treatment of patients with metastatic urothelial carcinoma is evolving with recent advances holding promise for improved outcomes. Historically, patients with metastatic urothelial carcinoma had a poor prognosis with no standard treatment options in the second-line setting. Currently, with an incr...

journal_title：Current opinion in supportive and palliative care

authors： Alimohamed NS,Sridhar SS

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent developments in the palliative management of gastrointestinal symptoms experienced by advanced cancer patients and provides a framework for detailing that encompasses education, assessment and monitoring, and treatment. RECENT FINDINGS:Although many viable treatment opti...

journal_title：Current opinion in supportive and palliative care

authors： Abernethy AP,Wheeler JL,Zafar SY

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Across all jurisdictions in which assisted dying is legally permissible, cancer is the primary reported underlying diagnosis. Therefore, oncologists are likely to be asked about assisted dying and should be equipped to respond to inquiries or requests for assisted dying. Because Medical Assistance in ...

journal_title：Current opinion in supportive and palliative care

authors： Selby D,Bean S

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To emphasize that the management of wounds represents a significant component within the overall supportive and palliative care of patients with advanced illness. It is also intended to clarify the linguistics that are commonly used around patients with wounds. RECENT FINDINGS:New paradigms for wound...

journal_title：Current opinion in supportive and palliative care

authors： Maida V

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Developments in the management of pulmonary arterial hypertension have significantly improved prognosis changing this from an acute to a chronic disease. Despite optimal treatment many patients still have a high-symptom burden both because of the disease and the side-effects of therapy, consequently t...

journal_title：Current opinion in supportive and palliative care

authors： Gin-Sing W

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Providing palliative care in Japan is one of the most important health issues. Understanding palliative care delivery systems of other countries is useful when developing and modifying palliative care systems worldwide. This review summarizes the current status of palliative care in Japan, focusing on...

journal_title：Current opinion in supportive and palliative care

authors： Morita T,Kizawa Y

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with heart failure seem particularly suited to palliative care having needs that fall within the prototypical palliative care domains. Despite this there is still much debate as to who should respond to these needs and when. RECENT FINDINGS:Since the early 1990s many studies have been publis...

journal_title：Current opinion in supportive and palliative care

authors： O'Leary N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Breathlessness is a high-volume problem with 10% of adults experiencing the symptom daily placing a heavy burden on the health and wider economy. As it worsens, they enter the specialist and hospital-based symptom services where costs quickly escalate and people may find themselves in a place not of t...

journal_title：Current opinion in supportive and palliative care

authors： Baxter N

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines recent literature on the psychosocial needs of and interventions for young women. We focus on the active treatment period given the toxicity of treatment, the incidence of anxiety, and depressive symptoms in these women during treatment. This review summarizes research relevant to...

journal_title：Current opinion in supportive and palliative care

authors： Fernandes-Taylor S,Adesoye T,Bloom JR

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cachexia, also known as disease-associated wasting, is an important factor in the mortality of many patients with diseases such as cancer, as well as renal and congestive heart failure. Yet the syndrome is not yet well defined, making diagnosis difficult and often subjective on the part of the physici...

journal_title：Current opinion in supportive and palliative care

authors： Fletcher AL,Marks DL

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the status of guidelines and recommendations for communication between patients with cancer and healthcare providers (HCPs) concerning fertility issues. RECENT FINDINGS:The timing, the type of information provided, and the openness of HCPs can all affect how patients with cancer ...

journal_title：Current opinion in supportive and palliative care

authors： Shen S,Zelkowitz P,Rosberger Z

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on chemotherapy in the management of patients with advanced urothelial cancer, with a look towards the future and the next generation of clinical trials. RECENT FINDINGS:The recognition that the maximum benefit from conventional combination chemotherapy has been achieved has led t...

journal_title：Current opinion in supportive and palliative care

authors： Calabrò F,Sternberg CN

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Constipation is a common symptom in palliative care patients that can generate considerable suffering due to both unpleasant physical symptoms and psychological preoccupations that may arise. There is uncertainty about the choice from varying recommendations for management of constipation and a varyin...

journal_title：Current opinion in supportive and palliative care

authors： Clemens KE,Klaschik E

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Overall survival of patients with pancreatic cancer is strongly conditioned by tumor biology and the incidence of malnutrition and metabolic disorders. In this landscape, the assessment of body composition is crucial to properly manage the clinical implications of muscle wasting. The pathogenesis of t...

journal_title：Current opinion in supportive and palliative care

authors： Basile D,Corvaja C,Caccialanza R,Aprile G

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Death is the inevitable consequence of life. Although clinicians are unlikely to accurately pinpoint when death is likely to occur in the people they care for, the death in a person with a diagnosis of malignant and nonmalignant tends to involve a period of predictable progressive clinical and functio...

journal_title：Current opinion in supportive and palliative care

authors： Watts T,Willis D,Noble S,Johnston B

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:It is difficult to hold an organized view of psychological research related to chronic pain. There are many different theories and variables and the volume of literature is vast. The purpose of this review is to highlight some key trends in this research in 2010. RECENT FINDINGS:We conducted a search...

journal_title：Current opinion in supportive and palliative care

authors： McCracken LM,Thompson M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:As the number of female cancer survivors continues to grow, there is a growing need to bridge the gap between the high rate of women's cancer-related sexual dysfunction and the lack of attention and intervention available to the majority of survivors who suffer from sexual problems. Previously identif...

journal_title：Current opinion in supportive and palliative care

authors： Bober SL,Reese JB,Barbera L,Bradford A,Carpenter KM,Goldfarb S,Carter J

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the advances in trial methodology and presents new methodologies to meet some of the challenges of conducting trials in a palliative care setting. To describe why this review is timely and relevant. RECENT FINDINGS:This review discusses the process required to conduct trials of ...

journal_title：Current opinion in supportive and palliative care

authors： Davis MP,Mitchell GK

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Young women (<45 years of age) diagnosed with breast cancer face increased risk of sexual dysfunction as a result of their cancer-directed treatment. We will review the recent literature examining this critical challenge and discuss current efforts to address sexual dysfunction. RECENT FINDINGS:In th...

journal_title：Current opinion in supportive and palliative care

authors： Zhou ES,Falk SJ,Bober SL

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This article describes the role of the PD-1 axis and reviews current data and future directions inhibiting PD-1 and PD-L1 in breast cancer. RECENT FINDINGS:Four phase I monotherapy expansion trials in patients with metastatic breast cancer have demonstrated low but durable single agent responses to P...

journal_title：Current opinion in supportive and palliative care

authors： Dawood S,Rugo HS

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Sequential anthracycline/taxane regimens are routinely used as neoadjuvant therapy (NAT) for locally advanced breast cancer. Unfortunately, the majority of patients do not achieve a pathological complete response (pCR). Efforts to improve pCR rates include the addition of novel targeted agents. The pu...

journal_title：Current opinion in supportive and palliative care

authors： Wilson S,Chia S

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:International bodies acknowledge that palliative care principles and access to palliative care services should be offered to persons living with and dying from advanced illness such as heart failure. Without an appropriately trained workforce, however, appropriate goals of care and associated reductio...

journal_title：Current opinion in supportive and palliative care

authors： Millerick Y,Armstrong I

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Many health professionals still believe that opioids shorten the lifespan of patients. This situation implies that the ethical doctrine of double effect is often invoked to justify their use in extreme circumstances. The objective of this study is to revise the evidence existing in the recently publis...

journal_title：Current opinion in supportive and palliative care

authors： López-Saca JM,Guzmán JL,Centeno C

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Gastrointestinal toxicity during chemotherapy is frequent. Symptomatic therapies for gastrointestinal toxicity, which do not address the underlying cause, may result in inadequate symptom control. With advances in curative treatment regimens, it becomes more important to minimize treatment toxicity wh...

journal_title：Current opinion in supportive and palliative care

authors： Andreyev HJ

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Opioids are potent drugs for the treatment of severe pain, but they are burdened by detrimental side-effects, such as respiratory depression, addiction, sedation and constipation. Their clinical application is undisputed in acute (e.g. perioperative) and cancer pain, but their use in chronic nonmalign...

journal_title：Current opinion in supportive and palliative care

authors： Stein C

更新日期：2020-06-01 00:00:00