Surgical approaches to metastatic spine disease.

abstract：PURPOSE OF REVIEW:The palliative care needs of people with interstitial lung disease (ILD) have recently been highlighted by the National Institute for Health and Care Excellence. All people with progressive ILD should receive best supportive care to improve symptom control and quality of life and where possible this s...

journal_title：Current opinion in supportive and palliative care

authors： Bajwah S,Yorke J

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The widespread use of prostate-specific antigen (PSA) resulted in stage migration of prostate cancer where androgen deprivation therapy (ADT) is administered for biochemical recurrence in patients following primary treatment. A proportion of these patients progress to a disease state termed nonmetasta...

journal_title：Current opinion in supportive and palliative care

authors： Traboulsi SL,Saad F

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The oligometastases is considered an intermediate state of the disease between localized and wide spread metastases. Local ablative therapy to oligometastatic prostate cancer is gaining significant traction and stereotactic body radiotherapy (SBRT) is an emerging treatment modality for this patient po...

journal_title：Current opinion in supportive and palliative care

authors： Niazi T,Elakshar S,Stroian G

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Pelvic pain is a common complaint of women that is frequently poorly managed. This review considers the current understanding of the mechanisms of pain perception and the development of chronic pain in the context of three gynaecological pain conditions. Recent advances in the management of these cond...

journal_title：Current opinion in supportive and palliative care

authors： Vincent K

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize current knowledge on promising immunotherapeutic agents and to provide a brief outline of current use of immunotherapeutic agents in patients with locally advanced or metastatic renal cell carcinoma (RCC). RECENT FINDINGS:Immunotherapy with mAbs directed against programed death cell prot...

journal_title：Current opinion in supportive and palliative care

authors： Nazzani S,Bazinet A,Karakiewicz PI

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the most recent studies that examine the efficacy of psychostimulants for the relief of symptoms such as asthenia and depression in cancer patients. RECENT FINDINGS:Although most research to date has focused on the use of methylphenidate for the relief of symptoms such as astheni...

journal_title：Current opinion in supportive and palliative care

authors： Portela MA,Rubiales AS,Centeno C

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Breathlessness is a high-volume problem with 10% of adults experiencing the symptom daily placing a heavy burden on the health and wider economy. As it worsens, they enter the specialist and hospital-based symptom services where costs quickly escalate and people may find themselves in a place not of t...

journal_title：Current opinion in supportive and palliative care

authors： Baxter N

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cross-sectional (C-S) imaging is now commonly used to measure body composition in clinical studies. This review highlights the advantages, limitations and suggested future directions for this technique. RECENT FINDINGS:Current understanding of C-S imaging reproducibility, tissue identification and se...

journal_title：Current opinion in supportive and palliative care

authors： MacDonald AJ,Greig CA,Baracos V

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Chemotherapy is a first-line treatment for many cancers; however, its use is hampered by a long list of side-effects. Gastrointestinal mucositis is a common and debilitating side-effect of anticancer therapy contributing to dose reductions, delays and cessation of treatment, greatly impacting clinical...

journal_title：Current opinion in supportive and palliative care

authors： McQuade RM,Al Thaalibi M,Nurgali K

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite a limited understanding of the exact mechanism, corticosteroids are commonly employed for pain control in patients with bone metastases. The aim of this review was to evaluate the efficacy of corticosteroid-mediated pain control in patients with bone metastases associated with solid cancers. ...

journal_title：Current opinion in supportive and palliative care

authors： Lim FMY,Bobrowski A,Agarwal A,Silva MF

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:RANK ligand (RANKL) plays a central role in the cancer-induced bone destruction that results from bone metastasis. The RANKL inhibitor denosumab was recently approved for the prevention of skeletal-related events (SREs) in patients with bone metastases from solid tumors. This review summarizes recent ...

journal_title：Current opinion in supportive and palliative care

authors： Lipton A,Jacobs I

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the mechanisms of muscle wasting and how inhibiting myostatin signaling affects them. RECENT FINDINGS:Myostatin signaling is critical for the understanding of the pathogenesis of muscle wasting as blocking signaling mitigates muscle losses in rodent models of catabolic diseases includin...

journal_title：Current opinion in supportive and palliative care

authors： Han HQ,Mitch WE

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with heart failure seem particularly suited to palliative care having needs that fall within the prototypical palliative care domains. Despite this there is still much debate as to who should respond to these needs and when. RECENT FINDINGS:Since the early 1990s many studies have been publis...

journal_title：Current opinion in supportive and palliative care

authors： O'Leary N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite its increasing prevalence and high mortality risk, heart failure is widely regarded as 'treatable'. Aggressive measures are employed even in its end stages. This review explores the clinical characteristics of heart failure, patterns of clinician response, and new data that may help to surmoun...

journal_title：Current opinion in supportive and palliative care

authors： Stuart B

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cachexia, also known as disease-associated wasting, is an important factor in the mortality of many patients with diseases such as cancer, as well as renal and congestive heart failure. Yet the syndrome is not yet well defined, making diagnosis difficult and often subjective on the part of the physici...

journal_title：Current opinion in supportive and palliative care

authors： Fletcher AL,Marks DL

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In the last 10 years, metastatic castration-resistant prostate cancer (mCRPC) treatment has completely changed. Several new agents have been shown to increase mCRPC patients' overall survival. The importance to define castration-resistant prostate cancer as metastatic and to enable earlier detection o...

journal_title：Current opinion in supportive and palliative care

authors： Beauregard JM,Pouliot F

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Care near the end of life is expensive and frequently not aligned with the expressed preferences of decedents, creating an opportunity to improve value, or increase quality while lowering cost. This review examines publications from 2017 and 2018 on interventions and policies associated with high-valu...

journal_title：Current opinion in supportive and palliative care

authors： Ankuda CK,Meier DE

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF THE REVIEW:The purpose of review is to critically present the evidence supporting the use of olanzapine, an atypical antipsychotic, as an antiemetic for cancer and chemotherapy-induced nausea and vomiting (CINV). RECENT FINDINGS:Two phase III clinical studies demonstrated superior efficacy of olanzapine in ...

journal_title：Current opinion in supportive and palliative care

authors： Bosnjak SM,Dimitrijevic J,Djordjevic F

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Right-sided heart failure, which is often present in the setting of advanced heart failure, is associated with cardiac cachexia, the cardiorenal syndrome, and adverse outcomes. Improved understanding of venous congestion of the splanchnic circulation, which may play a key role in the pathogenesis of r...

journal_title：Current opinion in supportive and palliative care

authors： Polsinelli VB,Marteau L,Shah SJ

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyspnea is the most common symptom in interstitial lung disease, yet little is known about its management. This review summarizes the available evidence for the treatment of dyspnea in interstitial lung disease. RECENT FINDINGS:The management of dyspnea in interstitial lung disease remains a challeng...

journal_title：Current opinion in supportive and palliative care

authors： Ryerson CJ,Collard HR,Pantilat SZ

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite recognition that opioids alleviate dyspnea in chronic obstructive pulmonary disease, many clinicians remain reluctant to use them outside of the final days of life. This article defines the term 'opioid responsiveness' as it pertains to dyspnea, and poses that it may be possible to predict mor...

journal_title：Current opinion in supportive and palliative care

authors： Horton R,Rocker G,Currow D

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss three emerging areas of research triggering new hypotheses for mechanisms of dyspnea. RECENT FINDINGS:There has been an emphasis on the importance of lung volumes in evaluating symptoms and lung function in patients with chronic obstructive pulmonary disease. Dyspnea intensity seems to mor...

journal_title：Current opinion in supportive and palliative care

authors： Rock LK,Schwartzstein RM

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Delirium is the most common and distressing neuropsychiatric syndrome in cancer patients. Few evidence-based treatment options are available due to the paucity of high quality of studies. In this review, we shall examine the literature on the use of neuroleptics to treat delirium in patients with adva...

journal_title：Current opinion in supportive and palliative care

authors： Hui D,Dev R,Bruera E

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Bone metastases in prostate cancer are often the cause of significant morbidity in patients with castrate-resistant disease, and several studies have shown significant pain palliation with systemic radionuclide treatment. The purpose of this review is to discuss the place of radionuclides in the dynam...

journal_title：Current opinion in supportive and palliative care

authors： Vengalil S,O'Sullivan JM,Parker CC

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to synthesize recent findings on anticipatory grief in caregivers, referring to its phenomenology, assessment and clinical interventions. RECENT FINDINGS:Recent literature illustrates the wide scope of the current use of the term anticipatory grief, reflecting caregivers' experiences...

journal_title：Current opinion in supportive and palliative care

authors： Coelho A,de Brito M,Barbosa A

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to consolidate the literature around pain assessment and management in older adults with dementia and to make recommendations for future research and practice developments. This review is provided following the introduction of guidelines for the assessment of pain that wer...

journal_title：Current opinion in supportive and palliative care

authors： Schofield P

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review compares the catabolic actions of tumour necrosis factor-alpha (TNF-alpha) and proteolysis-inducing factor (PIF) and their involvement in human cancer cachexia. RECENT FINDINGS:TNF-alpha has a direct catabolic effect on skeletal muscle and adipose tissue, whereas PIF only has an effect on...

journal_title：Current opinion in supportive and palliative care

authors： Tisdale MJ

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe a new strategy that aimed to facilitate opioid prescription for better pain management. RECENT FINDINGS:The International Association of Hospice and Palliative Care recently develop a single prescription package (drugs and dosing) with one opioid, one laxative, and one antiemetic for the ...

journal_title：Current opinion in supportive and palliative care

authors： Vignaroli E,Wenk R

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The study provides a review of current evidence about the role of complex nonpharmacological strategies in managing the multidimensional components of the breathlessness experience for individuals with life-limiting conditions. RECENT FINDINGS:Evidence continues to demonstrate the significant impact ...

journal_title：Current opinion in supportive and palliative care

authors： Yates P,Zhao I

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Good communication is the cornerstone of interprofessional care teams providing optimized quality patient care. Over the last decade, advances in technology have provided tools to improve communication; however, opportunities still exist for innovation and implementation. RECENT FINDINGS:The literatu...

journal_title：Current opinion in supportive and palliative care

authors： D'Alimonte L,McLaney E,Di Prospero L

更新日期：2019-03-01 00:00:00