Abstract:
PURPOSE OF REVIEW:The oligometastases is considered an intermediate state of the disease between localized and wide spread metastases. Local ablative therapy to oligometastatic prostate cancer is gaining significant traction and stereotactic body radiotherapy (SBRT) is an emerging treatment modality for this patient population. In this review, we report our literature review of SBRT to prostate oligometastases. Current evidence on the role of SBRT in oligometastatic prostate cancer reported in the last 10 years was summarized. Criteria for inclusion included studies with prostate cancer only as the primary site. RECENT FINDINGS:The unique properties of the oligometastatic prostate cancer appear to carry a better prognosis than wide spread metastatic disease, especially if these metastases are amenable to local ablative therapies. Our literature review revealed that local ablative therapy, using SBRT to prostate oligometastases, is associated with significant 2-years local control and acceptable toxicity profile. SUMMARY:SBRT to oligometastatic prostate cancer patients is feasible and carries an acceptable toxicity profile. The randomized phase II and III trials, currently underway, should clearly define the real benefit of this approach on progression-free and overall survival outcomes.
journal_name
Curr Opin Support Palliat Carejournal_title
Current opinion in supportive and palliative careauthors
Niazi T,Elakshar S,Stroian Gdoi
10.1097/SPC.0000000000000371subject
Has Abstractpub_date
2018-09-01 00:00:00pages
351-358issue
3eissn
1751-4258issn
1751-4266journal_volume
12pub_type
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journal_title:Current opinion in supportive and palliative care
pub_type: 杂志文章,评审
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
pub_type: 杂志文章,评审
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journal_title:Current opinion in supportive and palliative care
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doi:10.1097/SPC.0b013e3282f1aad1
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
pub_type: 杂志文章,评审
doi:10.1097/SPC.0b013e32832531ce
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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