The last days of life: symptom burden and impact on nutrition and hydration in cancer patients.

abstract：PURPOSE OF REVIEW:To discuss three emerging areas of research triggering new hypotheses for mechanisms of dyspnea. RECENT FINDINGS:There has been an emphasis on the importance of lung volumes in evaluating symptoms and lung function in patients with chronic obstructive pulmonary disease. Dyspnea intensity seems to mor...

journal_title：Current opinion in supportive and palliative care

authors： Rock LK,Schwartzstein RM

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent developments in the management of gastrointestinal symptoms experienced by cancer patients and provides a framework for education, assessment and monitoring, and treatment. RECENT FINDINGS:Although many viable treatment options exist, gastrointestinal symptoms - particul...

journal_title：Current opinion in supportive and palliative care

authors： Rangwala F,Zafar SY,Abernethy AP

更新日期：2012-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Highlight the difficulties patients, physicians, and the global economy face in relation to treatment of structural heart diseases. It is easy to be carried away by the excitement of medical advancement; however, it is difficult to demonstrate restraint. Transcatheter aortic valve replacement (TAVR) i...

journal_title：Current opinion in supportive and palliative care

authors： German KS,Kalra A

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Death is the inevitable consequence of life. Although clinicians are unlikely to accurately pinpoint when death is likely to occur in the people they care for, the death in a person with a diagnosis of malignant and nonmalignant tends to involve a period of predictable progressive clinical and functio...

journal_title：Current opinion in supportive and palliative care

authors： Watts T,Willis D,Noble S,Johnston B

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To emphasize that the management of wounds represents a significant component within the overall supportive and palliative care of patients with advanced illness. It is also intended to clarify the linguistics that are commonly used around patients with wounds. RECENT FINDINGS:New paradigms for wound...

journal_title：Current opinion in supportive and palliative care

authors： Maida V

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The serotonergic system has long been linked to migraine but recent studies highlight how much is still unclear about this link. And recent data add to the uncertainty of where/how triptans act and why they are headache specific. RECENT FINDINGS:Markers of 5HT levels in the brains of migraine patient...

journal_title：Current opinion in supportive and palliative care

authors： Dussor G

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the mechanisms of muscle wasting and how inhibiting myostatin signaling affects them. RECENT FINDINGS:Myostatin signaling is critical for the understanding of the pathogenesis of muscle wasting as blocking signaling mitigates muscle losses in rodent models of catabolic diseases includin...

journal_title：Current opinion in supportive and palliative care

authors： Han HQ,Mitch WE

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Gastrointestinal toxicity during chemotherapy is frequent. Symptomatic therapies for gastrointestinal toxicity, which do not address the underlying cause, may result in inadequate symptom control. With advances in curative treatment regimens, it becomes more important to minimize treatment toxicity wh...

journal_title：Current opinion in supportive and palliative care

authors： Andreyev HJ

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Overall survival of patients with pancreatic cancer is strongly conditioned by tumor biology and the incidence of malnutrition and metabolic disorders. In this landscape, the assessment of body composition is crucial to properly manage the clinical implications of muscle wasting. The pathogenesis of t...

journal_title：Current opinion in supportive and palliative care

authors： Basile D,Corvaja C,Caccialanza R,Aprile G

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the psychosocial support of people affected by cancer anorexia, drawing on recent publications. RECENT FINDINGS:Recent studies describe the problem of distress in response to cancer anorexia. There are propositions of appropriate support and calls for the development of psychosocial interv...

journal_title：Current opinion in supportive and palliative care

authors： Hopkinson JB

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Care near the end of life is expensive and frequently not aligned with the expressed preferences of decedents, creating an opportunity to improve value, or increase quality while lowering cost. This review examines publications from 2017 and 2018 on interventions and policies associated with high-valu...

journal_title：Current opinion in supportive and palliative care

authors： Ankuda CK,Meier DE

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Determining which palliative interventions are appropriate within and between groups remains difficult because of the lack of prospective studies and heterogeneity in dyspnoea context, assessment and reporting. This review presents an evolution of dyspnoea theories, summarizes literature published dur...

journal_title：Current opinion in supportive and palliative care

authors： Williams M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Bone metastases in prostate cancer are often the cause of significant morbidity in patients with castrate-resistant disease, and several studies have shown significant pain palliation with systemic radionuclide treatment. The purpose of this review is to discuss the place of radionuclides in the dynam...

journal_title：Current opinion in supportive and palliative care

authors： Vengalil S,O'Sullivan JM,Parker CC

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:As the number of female cancer survivors continues to grow, there is a growing need to bridge the gap between the high rate of women's cancer-related sexual dysfunction and the lack of attention and intervention available to the majority of survivors who suffer from sexual problems. Previously identif...

journal_title：Current opinion in supportive and palliative care

authors： Bober SL,Reese JB,Barbera L,Bradford A,Carpenter KM,Goldfarb S,Carter J

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Cross-sectional (C-S) imaging is now commonly used to measure body composition in clinical studies. This review highlights the advantages, limitations and suggested future directions for this technique. RECENT FINDINGS:Current understanding of C-S imaging reproducibility, tissue identification and se...

journal_title：Current opinion in supportive and palliative care

authors： MacDonald AJ,Greig CA,Baracos V

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize current knowledge on promising immunotherapeutic agents and to provide a brief outline of current use of immunotherapeutic agents in patients with locally advanced or metastatic renal cell carcinoma (RCC). RECENT FINDINGS:Immunotherapy with mAbs directed against programed death cell prot...

journal_title：Current opinion in supportive and palliative care

authors： Nazzani S,Bazinet A,Karakiewicz PI

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the role of lung volume reduction surgery (LVRS) for the management of refractory dyspnea and other debilitating conditions in patients with chronic obstructive pulmonary disease. Recent studies, including a randomized trial comparing LVRS to medical therapy, are analyzed. RECEN...

journal_title：Current opinion in supportive and palliative care

authors： Shah AA,D'Amico TA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Delirium is the most common and distressing neuropsychiatric syndrome in cancer patients. Few evidence-based treatment options are available due to the paucity of high quality of studies. In this review, we shall examine the literature on the use of neuroleptics to treat delirium in patients with adva...

journal_title：Current opinion in supportive and palliative care

authors： Hui D,Dev R,Bruera E

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Palliative sedation has been the subject of intensive debate since its first appearance in 1990. In a 2010 review of palliative sedation, the following areas were identified as lacking in consensus: inconsistent terminology, its use in nonphysical suffering, the ongoing experience of distress, and con...

journal_title：Current opinion in supportive and palliative care

authors： Henry B

更新日期：2016-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines recent literature on the psychosocial needs of and interventions for young women. We focus on the active treatment period given the toxicity of treatment, the incidence of anxiety, and depressive symptoms in these women during treatment. This review summarizes research relevant to...

journal_title：Current opinion in supportive and palliative care

authors： Fernandes-Taylor S,Adesoye T,Bloom JR

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The palliative care needs of people with interstitial lung disease (ILD) have recently been highlighted by the National Institute for Health and Care Excellence. All people with progressive ILD should receive best supportive care to improve symptom control and quality of life and where possible this s...

journal_title：Current opinion in supportive and palliative care

authors： Bajwah S,Yorke J

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The oligometastases is considered an intermediate state of the disease between localized and wide spread metastases. Local ablative therapy to oligometastatic prostate cancer is gaining significant traction and stereotactic body radiotherapy (SBRT) is an emerging treatment modality for this patient po...

journal_title：Current opinion in supportive and palliative care

authors： Niazi T,Elakshar S,Stroian G

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The balance between the rates of protein synthesis and protein degradation governs the maintenance of muscle mass in the body. The main purpose of this review is to highlight the latest understanding of the various pathways that maintain this balance between muscle atrophy and hypertrophy. RECENT FIN...

journal_title：Current opinion in supportive and palliative care

authors： Banerjee A,Guttridge DC

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the advances in trial methodology and presents new methodologies to meet some of the challenges of conducting trials in a palliative care setting. To describe why this review is timely and relevant. RECENT FINDINGS:This review discusses the process required to conduct trials of ...

journal_title：Current opinion in supportive and palliative care

authors： Davis MP,Mitchell GK

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the status of guidelines and recommendations for communication between patients with cancer and healthcare providers (HCPs) concerning fertility issues. RECENT FINDINGS:The timing, the type of information provided, and the openness of HCPs can all affect how patients with cancer ...

journal_title：Current opinion in supportive and palliative care

authors： Shen S,Zelkowitz P,Rosberger Z

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This article describes the role of the PD-1 axis and reviews current data and future directions inhibiting PD-1 and PD-L1 in breast cancer. RECENT FINDINGS:Four phase I monotherapy expansion trials in patients with metastatic breast cancer have demonstrated low but durable single agent responses to P...

journal_title：Current opinion in supportive and palliative care

authors： Dawood S,Rugo HS

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with heart failure seem particularly suited to palliative care having needs that fall within the prototypical palliative care domains. Despite this there is still much debate as to who should respond to these needs and when. RECENT FINDINGS:Since the early 1990s many studies have been publis...

journal_title：Current opinion in supportive and palliative care

authors： O'Leary N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe a new strategy that aimed to facilitate opioid prescription for better pain management. RECENT FINDINGS:The International Association of Hospice and Palliative Care recently develop a single prescription package (drugs and dosing) with one opioid, one laxative, and one antiemetic for the ...

journal_title：Current opinion in supportive and palliative care

authors： Vignaroli E,Wenk R

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Many health professionals still believe that opioids shorten the lifespan of patients. This situation implies that the ethical doctrine of double effect is often invoked to justify their use in extreme circumstances. The objective of this study is to revise the evidence existing in the recently publis...

journal_title：Current opinion in supportive and palliative care

authors： López-Saca JM,Guzmán JL,Centeno C

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to consolidate the literature around pain assessment and management in older adults with dementia and to make recommendations for future research and practice developments. This review is provided following the introduction of guidelines for the assessment of pain that wer...

journal_title：Current opinion in supportive and palliative care

authors： Schofield P

更新日期：2008-06-01 00:00:00