Role of the vestibular system in the arterial pressure response to parabolic-flight-induced gravitational changes in human subjects.

Abstract:

:Arterial pressure (AP) is known to fluctuate during parabolic-flight-induced gravitational changes in human subjects, increasing during hypergravity and decreasing during microgravity. In this study, we examined whether the vestibular system participates in the AP response to the gravitational changes induced by parabolic flight in human subjects. Eight subjects performed parabolic flights in a supine position as their AP was measured. Their vestibular inputs during the gravitational changes were reversibly masked by artificial electrical stimulation (galvanic vestibular stimulation, GVS). The AP responses during the parabolas were then compared between the GVS-off and GVS-on conditions. AP increased during hypergravity and decreased during microgravity. The AP responses at the onset of hypergravity and microgravity were abolished by GVS. These results indicate that the vestibular system elicits pressor and depressor responses during parabolic-flight-induced hypergravity and microgravity, respectively.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Iwata C,Abe C,Tanaka K,Morita H

doi

10.1016/j.neulet.2011.03.052

subject

Has Abstract

pub_date

2011-05-16 00:00:00

pages

121-5

issue

2

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(11)00356-9

journal_volume

495

pub_type

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