Abstract:
:Arterial pressure (AP) is known to fluctuate during parabolic-flight-induced gravitational changes in human subjects, increasing during hypergravity and decreasing during microgravity. In this study, we examined whether the vestibular system participates in the AP response to the gravitational changes induced by parabolic flight in human subjects. Eight subjects performed parabolic flights in a supine position as their AP was measured. Their vestibular inputs during the gravitational changes were reversibly masked by artificial electrical stimulation (galvanic vestibular stimulation, GVS). The AP responses during the parabolas were then compared between the GVS-off and GVS-on conditions. AP increased during hypergravity and decreased during microgravity. The AP responses at the onset of hypergravity and microgravity were abolished by GVS. These results indicate that the vestibular system elicits pressor and depressor responses during parabolic-flight-induced hypergravity and microgravity, respectively.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Iwata C,Abe C,Tanaka K,Morita Hdoi
10.1016/j.neulet.2011.03.052subject
Has Abstractpub_date
2011-05-16 00:00:00pages
121-5issue
2eissn
0304-3940issn
1872-7972pii
S0304-3940(11)00356-9journal_volume
495pub_type
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