Abstract：
BACKGROUND:Slow wave sleep (SWS) has been theorized as reflecting a homeostatic sleep process and is considered a state of recuperation. SWS is reduced in obstructive sleep apnea (OSA) patients, but SWS has not been specifically studied in respiratory failure patients. The aim of this study is to investigate SWS in predominantly hypercapnic respiratory failure patients. METHODS:We analyzed sleep and arterial blood gas records of all 97 respiratory failure patients who underwent polysomnography and bilevel non-invasive ventilation (NIV) treatment in our laboratory from 2008 to July 2009. We also analyzed 32 initial diagnostic study data from these 97 patients. RESULTS:The 97 patients had an average age of 58±15 (SD) years. Total sleep time was 320.3±82.8 (SD) min of which 32.9%±15.4 (%) was spent in SWS. This high percentage SWS correlated positively with awake arterial CO(2) pressure (PCO(2)) in both the 97 treatment studies (r=0.35, p=0.001) and the 32 initial diagnostic studies (r=0.40, p=0.025). The relationship was particularly apparent in patients with obesity hypoventilation syndrome or overlap syndrome. Statistical modelling identified three significant predictor variables for SWS across both diagnostic and NIV nights: PCO(2), arousal index and female gender. CONCLUSIONS:Patients with respiratory failure have a high percentage of EEG assessed SWS which is in part determined by disease specific variables such as hypercapnia as well as by traditional SWS determinants such as sleep fragmentation and gender.
journal_name
Sleep Medjournal_title
Sleep medicineauthors
Wang D,Piper AJ,Wong KK,Yee BJ,Marshall NS,Dijk DJ,Grunstein RRdoi
10.1016/j.sleep.2011.01.007subject
Has Abstractpub_date
2011-04-01 00:00:00pages
378-83issue
4eissn
1389-9457issn
1878-5506pii
S1389-9457(11)00058-Xjournal_volume
12pub_type
杂志文章相关文献
SLEEP MEDICINE文献大全abstract：STUDY OBJECTIVES:Sleep disorders are significant problems in patients with rheumatoid arthritis (RA) and are associated with poor quality of life. Irisin is myokine which may have anti-inflammatory and energy regulatory roles. This study assessed the association of serum irisin levels with the quality of sleep and dise...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.10.021
更新日期：2020-03-01 00:00:00
abstract：:Sixty-five years after the discovery of rapid eye movement (REM) sleep, the reasons why we sleep and why we need two states of sleep are still largely unclear. Moreover, the functional relationship between the two types of sleep remains the matter of much conjecture. Several questions come to mind. How does sleep regu...
journal_title：Sleep medicine
pub_type： 杂志文章,评审
doi：10.1016/j.sleep.2020.02.004
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:Pulse wave attenuation, which occurs in association with obstructive sleep apnea (OSA), is sympathetically mediated. We compared the effect of Doxazosin (DO, a peripheral alpha-receptor inhibitor) and Enalapril (EN, an ACE inhibitor) on digital vasoconstriction and nocturnal blood pressure (BP) in hypertensiv...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2009.10.004
更新日期：2010-03-01 00:00:00
abstract：STUDY OBJECTIVES:Many healthcare workers live with sleep disorders and may be unaware of their condition. We aimed to ascertain sleep disorder symptoms including high-risk obstructive sleep apnea (hrOSA), significant insomnia, and excessive daytime sleepiness (EDS) by work shift in a sample of healthcare workers. We ai...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.07.028
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Restless Legs Syndrome (RLS) is characterized by uncomfortable nocturnal sensations in the legs making sedentary activities and sleep difficult, and is thus linked with psychosocial distress. Due to the symptomatology and neurobiology of RLS (disrupting brain iron and dopamine) it is likely that RLS associat...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.02.007
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND AND PURPOSE:This study analyzes sawtooth waves (STW), a characteristic feature of rapid eye movement (REM) sleep, in temporal lobe epilepsy patients in order to test the hypothesis of STW dysfunction in this population. METHODS:Polysomnographic records from 16 patients with temporal lobe epilepsy and 11 con...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2005.02.005
更新日期：2005-07-01 00:00:00
abstract：INTRODUCTION:Sleep restriction and sleep disorders are common causes of excessive daytime sleepiness (EDS). Medical disorders (MD) can also cause EDS, but previous studies have used non-standardized measures, selected samples, or have examined EDS in singular disorders. This study describes the relative degree of EDS a...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2010.04.010
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:We examined the relationship between baseline substantia nigra (SN) echogenicity on transcranial sonography (TCS) images and medium-to long-term developments of Parkinson's disease (PD) and dementia with Lewy bodies (DLB) in idiopathic RBD (IRBD) patients. METHODS:From 2007-2009, TCS and odor identification...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.09.008
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVES:The effects of antiepileptic drugs (AEDs) on sleep architecture are not well understood, especially in patients with localization-related epilepsy, in whom seizures themselves can disrupt sleep. To clarify the effects of AEDs on sleep architecture, we performed a prospective study, looking at sleep architect...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/s1389-9457(02)00217-4
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE/BACKGROUND:Cataplexy is the pathognomonic symptom of narcolepsy type 1 (NT1). Since it is considered difficult to be directly observed or documented by clinicians, its diagnosis relies mainly on history taking. Our study aimed at testing the feasibility of a standardized video recording procedure under emotio...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2017.08.021
更新日期：2019-01-01 00:00:00
abstract：:We report a new, pathologically verified Italian case of fatal familial insomnia, whose clinical presentation was characterised by complex behavioural disturbances, suggesting wakefulness/NREM/REM combinations. ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2008.05.007
更新日期：2009-05-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Studies examining the impact of daytime preoccupations with sleep are rare. The aim of the present study was to determine whether daytime preoccupations mediate the relationship between anxiety and attributions for poor sleep within older adults. METHOD:A cross-sectional study examined the media...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2006.08.011
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:Executive dysfunction (ED) is often observed in subjects diagnosed with obstructive sleep apnea (OSA), but their assessment requires facilities that are not always available. We aim to evaluate the extent to which Frontal Assessment Battery (FAB) discriminates ED in newly diagnosed, untreated, and without-co...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2017.11.1122
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:The aims of this research were to estimate prevalence of insomnia, describe the utilization patterns of physician office services and prescription medications for insomnia, and estimate related costs in a Medicaid population. METHODS:A cross-sectional descriptive analysis using data from the West Virginia (...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2009.09.012
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:The mechanisms involved in sleep perception are not widely known. Therefore, we believe that investigating this phenomenon is the best way to understand some of the mechanisms involved in several sleep disturbances, particularly insomnias. OBJECTIVE:The objective of our study was to evaluate sleep perceptio...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2008.06.016
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has been considered a promising technique for the treatment of primary insomnia. However, its efficacy and placebo response remains unclear due to limited clinical data. Therefore, we conducted a systematic review to examine the efficacy and placebo respons...
journal_title：Sleep medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.sleep.2019.05.008
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:Ramelteon, an MT(1)/MT(2) melatonin receptor agonist, was evaluated for its ability to reduce sleep-onset difficulties associated with eastward jet travel. METHODS:Healthy adults (n=110) with a history of jet lag sleep disturbances were flown eastward across five time zones from Hawaii to the east coast of t...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2010.03.010
更新日期：2010-06-01 00:00:00
abstract：INTRODUCTION:Obstructive sleep apnea (OSA) was associated with increased incidence of all cancers. We aimed to determine the risk for primary central nervous system (CNS) cancers in patients with sleep apnea syndrome. METHODS:A total of 23,055 incident cases of newly diagnosed sleep apnea syndrome (sleep apnea group) ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2013.11.782
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVES:To investigate potential delays in endogenous melatonin in individuals with obsessive-compulsive disorder (OCD). METHODS:First, data are presented for 15 individuals with OCD and matched healthy controls. Next, nine additional participants with OCD who did not have matched controls were added, resulting in ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.03.021
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:It is now recognized that the vast majority of individuals with typical RBD will develop a synucleinopathy; usually 11-16 years after symptom onset. Parasomnia Overlap Disorder (POD) with adolescent-onset dream enactment behavior with phenoconversion to neurodegenerative disease after a long latency has not ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.01.041
更新日期：2019-05-01 00:00:00
abstract：STUDY OBJECTIVES:Theoretical accounts of the progression of insomnia from acute to chronic are lacking. A framework is proposed and tested to examine differences in cognitive coping styles between acute and chronic insomniacs and the relation of cognitive processing and sleep hygiene to causal attributions of insomnia....
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/s1389-9457(02)00039-4
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVES:Restless legs syndrome (RLS) is a common neurological disorder but it is not sufficiently recognized in children and adolescents. It often overlaps with growing pains in children, and as a result the clinical characteristics of pediatric RLS are not well studied, especially in Asia. The purpose of this study...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.12.016
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:The popularity of biofeedback as a non-pharmacological treatment option for insomnia has increased in recent times despite inconsistent empirical evidence for its therapeutic efficacy. OBJECTIVE:The purpose of the current review was to systematically assess the efficacy of using biofeedback to treat insomni...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.12.011
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Pre-eclampsia is a leading cause of maternal-fetal morbidity and mortality. Significant overlap exists between the risk factors for pre-eclampsia and sleep-disordered breathing. Nasal continuous positive airway pressure (CPAP) has been proposed as therapy for pre-eclampsia. This prospective, longitudinal stu...
journal_title：Sleep medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.sleep.2007.04.020
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVES:Sleep is critical for adolescent health and is influenced by the family environment. In our study, we examined if family structure defined as single- vs. two-parent households affected adolescent sleep. METHODS:Participants were 242 (57% black; 47% boys) healthy adolescents (mean age, 15.7 years). Sleep was...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2013.10.012
更新日期：2014-02-01 00:00:00
abstract：:Objective: To replicate the left minus right (L-R) hemisphere EEG power shifts coupled to rapid eye movement (REM) and non-rapid eye movement (NREM) sleep observed in 1972 by Goldstein (Physiol Behav (1972) 811), and to characterize the L-R EEG power spectra for total EEG, delta, theta, alpha and beta bands.Background...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/s1389-9457(00)00066-6
更新日期：2001-07-01 00:00:00
abstract：:Circadian clocks are intracellular molecular mechanisms designed to allow the cell, organ, and organism to prepare for an anticipated stimulus prior to its onset. In order for circadian clocks to maintain their selective advantage, they must be entrained to the environment. Light, sound, temperature, physical activity...
journal_title：Sleep medicine
pub_type： 杂志文章,评审
doi：10.1016/j.sleep.2006.12.010
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:Nocturnal eating behavior is shared by patients affected by a parasomnia, sleep-related eating disorder (SRED), and several eating disorders such as night eating syndrome (NES) and binge-eating disorder (BED); however, the differential clinical features of these patients have been poorly studied, with persist...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2014.12.020
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVES:Levels of steroid hormones such as androgens and cortisol exhibit circadian variation, and their fluctuations are related to the sleep-wake cycle. Currently, the functional role of different stages of sleep in steroid hormone secretion remains unclear. The present study aims to explore the effect of slow-wav...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2018.04.012
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:To explore the correlates of nocturnal sleep duration, nocturnal sleep variability, and nocturnal sleep problems in a sample of Australian toddlers. METHODS:Participants were 173 toddlers (average age 19.7 ± 4.1 months) from the GET UP! STUDY:Nocturnal sleep duration, nocturnal sleep variability, nap(s) and...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2018.08.035
更新日期：2019-01-01 00:00:00
