Abstract:
:Sixty-five years after the discovery of rapid eye movement (REM) sleep, the reasons why we sleep and why we need two states of sleep are still largely unclear. Moreover, the functional relationship between the two types of sleep remains the matter of much conjecture. Several questions come to mind. How does sleep regulation in monophasic and polyphasic animals compare? What are the circadian and homeostatic influences on both states? Are non-rapid eye movement (NREM) and REM states dependent on each other, or are they regulated independently? What about long-term and short-term regulation? In addition, what determines the number and duration of cycles per night? What roles are played by temperature and energy allocation? The evidence collected over the years regarding these questions is summarized here, trying to address each issue.
journal_name
Sleep Medjournal_title
Sleep medicineauthors
Le Bon Odoi
10.1016/j.sleep.2020.02.004subject
Has Abstractpub_date
2020-06-01 00:00:00pages
6-16eissn
1389-9457issn
1878-5506pii
S1389-9457(20)30075-7journal_volume
70pub_type
杂志文章,评审相关文献
SLEEP MEDICINE文献大全abstract::Functional neuroimaging studies may contribute to elucidate pathophysiological mechanisms of the restless legs syndrome (RLS) which still remain unclear. Studies in patients with RLS have been performed using functional magnetic resonance imaging (fMRI), single photon emission computed tomography (SPECT) and, more rec...
journal_title:Sleep medicine
pub_type: 杂志文章,评审
doi:10.1016/j.sleep.2004.01.009
更新日期:2004-07-01 00:00:00
abstract::Sleep disturbances are common in extrapyramidal diseases, including not only insomnia but excessive daytime sleepiness and parasomnias. In particular, complaints related to sleep are extremely common among patients affected by Parkinson's disease (PD). The underlying causes may include: patient age, associated illness...
journal_title:Sleep medicine
pub_type: 杂志文章,评审
doi:10.1016/j.sleep.2003.10.012
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Hypoxia plays an important role in the development of solid tumors. Intermittent hypoxia is the hallmark of sleep apnea (SA). We tested the hypothesis that SA may increase the risk of breast cancer in Taiwan by using a population-based data set. METHODS:Our study cohort consisted of women diagnosed with SA ...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2014.05.026
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:Large prospective studies have established that sleep-disordered breathing (SDB) is associated with an increased incidence of cardiovascular and cerebrovascular diseases. Heterogeneous results have been published about SDB and ischaemic stroke mechanism. The aim of this study was to evaluate the relationship...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2015.07.031
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The pressures generated within the upper esophageal sphincter (P(UES)) and lower esophageal sphincter (P(LES)) reflect the integrity of these barriers to gastroesophageal and pharyngoesophageal reflux, respectively. This study sought to describe the effects of sleep, respiration and posture on th...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2006.08.016
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Studies examining the impact of daytime preoccupations with sleep are rare. The aim of the present study was to determine whether daytime preoccupations mediate the relationship between anxiety and attributions for poor sleep within older adults. METHOD:A cross-sectional study examined the media...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2006.08.011
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND AND AIM:Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) is associated with glucose dysmetabolism and insulin resistance, therefore the amelioration of breathing disturbances during sleep can allegedly modify the levels of markers of glucose regulation and insulin resistance, such as glycated hemoglobin, fa...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2008.10.004
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:We examined the relationship between baseline substantia nigra (SN) echogenicity on transcranial sonography (TCS) images and medium-to long-term developments of Parkinson's disease (PD) and dementia with Lewy bodies (DLB) in idiopathic RBD (IRBD) patients. METHODS:From 2007-2009, TCS and odor identification...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.09.008
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:As the relationships of sleep-wake schedule and mealtime with children's behaviors have not often been studied together, we investigated the relationships of these lifestyles variables with preschool children's well-being. METHODS:Using a network survey, we investigated several lifestyle variables of 1000 fa...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.03.023
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To evaluate, both polysomnographically and by subjective scales, the efficacy and safety profile of pramipexole for restless legs syndrome (RLS) via a 3-week, double-blind, placebo-controlled, parallel-group, dose-ranging study. METHODS:At baseline and after 3 weeks, periodic limb movements (PLM) and sleep p...
journal_title:Sleep medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.sleep.2008.05.014
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To assess the independent and combined effects of night sleep duration and sleep quality on depressive symptoms. METHODS:A total of 28,202 participants (11,236 males and 16,966 females) aged 18-79 years from the Henan Rural Cohort were included in this study. Night sleep duration and sleep quality were defin...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.10.022
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the association of sleep problems with weight and waist size gain during four years of follow-up. METHODS:We investigated 13,030 participants (35-74 years) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a multicentric cohort conducted with civil servants from six academic inst...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2020.06.017
更新日期:2020-09-01 00:00:00
abstract::Objective: (i) Evaluation of the clinical differences and similarities presented by patients diagnosed as OSAS and UARS subjects. (ii) Evaluation of the ability of a sleep disorders specialist to dissociate the two syndromes based upon clinical evaluation.Population: 314 subjects were included. They were referred to a...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/s1389-9457(99)00011-8
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the diagnostic accuracy of the standard periodic leg movement during sleep (PLMS) index, a recently introduced alternative one, and the periodicity index (PI) for restless legs syndrome (RLS). SUBJECTS AND METHODS:A total of 107 patients with RLS were retrospectively identified and included (47 m...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2015.11.018
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:We aimed to determine if timing of polysomnography (PSG) influences the diagnosis of obstructive sleep apnea (OSA) in acute myocardial infarction (AMI) or stable coronary artery disease (CAD). METHODS:A total of 160 patients admitted with AMI or stable CAD were consecutively recruited for either in-hospital...
journal_title:Sleep medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.sleep.2013.03.025
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Noise in the vicinity of airports is a public health issue. Exposure to aircraft noise has been shown to have adverse effects on health and particularly on sleep. Many studies support the hypothesis that noise at night can affect subjective sleep quality. Fewer studies, however, have performed objective meas...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2018.10.013
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:to explore the status of concentration of klotho and fibroblast growth factor 23 (FGF23) in cerebrospinal fluid (CSF) of patients with narcolepsy. PATIENTS/METHODS:59 patients with narcolepsy and 17 control individuals were enrolled. We used radioimmunoassay, human klotho enzyme-linked immunosorbent assay (E...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2020.11.037
更新日期:2020-12-15 00:00:00
abstract:STUDY OBJECTIVES:Early life determinants of sleep problems are mostly unknown. The first 1000 days of life (ie, the time between conception and a child's second birthday) is a period where the foundations for optimum health, growth and neurodevelopment are established. The aim of this explorative study is to identify p...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.12.020
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Contradictory data have been published on the influence of Apolipoprotein E (APOE) epsilon4 allele on obstructive sleep apnea (OSA). The aims of this study were to confirm the presence of specific neuropsychological changes in OSA patients carrying the APOE epsilon4 allele and to clarify if these changes are...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2007.10.015
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES/BACKGROUND:Because both REM sleep behavior disorder (RBD) and Obstructive Sleep Apnea (OSA) can present with similar symptoms, it is important to understand the influence of OSA in the clinical manifestations of RBD and whether RBD modulates OSA severity. Our objectives were to compare: 1. the intensity of n...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2017.05.012
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To investigate the associations between sleep disturbances in mid-life and late-life and late-life cognitive status. METHODS:In four population-based studies (three Swedish studies: H70 study, Kungsholmen Project (KP) and The Swedish Panel Study of Living Conditions of the Oldest Old (SWEOLD); and one Finnis...
journal_title:Sleep medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.sleep.2017.11.1149
更新日期:2018-12-01 00:00:00
abstract::Background: The measurement of impedance permits reliable detection of obstructive apneas, hypopneas and upper airways resistance syndrome.Objective: To establish whether impedance-controlled self-adjusting positive airway pressure therapy (APAP(FOT)) is equally as good as constant continuous positive airway pressure ...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/s1389-9457(00)00048-4
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:During the outbreak of the COVID-19 pandemic in 2020, high schools closed or transitioned to remote teaching. The aim of this study was to describe how the COVID-19 related school shutdown impacted the sleep behaviors of typically developing adolescents. METHODS:A qualitative study was conducted between Apri...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2020.09.015
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to investigate the impact of sleep on osteoporosis. METHODS:The study used a baseline examination of the Hiroshima Sleep and Healthcare study, which was a cross-sectional and cohort study that addressed the association of sleep habits with lifestyle-related diseases. A total ...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2016.06.029
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Circadian disruptions can contribute to accelerated aging, and the circadian system regulates cognitive and physical functions; therefore, circadian markers (eg, melatonin) may be associated with key aspects of healthy aging and longevity. OBJECTIVE:To evaluate urinary melatonin levels in relation to cognit...
journal_title:Sleep medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.sleep.2016.07.006
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:Important adjustments in the autonomic nervous system occur during sleep. Bradycardia, due to increased vagal tone, and hypotension, caused by reduction of sympathetic activity, may occur during non rapid eye movement (REM) sleep (NREM). Increased sympathetic activity, causing increased heart rate, is conver...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2012.03.001
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:Adolescents are predisposed to short sleep duration and irregular sleep patterns due to certain host characteristics (e.g., age, pubertal status, gender, ethnicity, socioeconomic class, and neighborhood distress) and health-related variables (e.g., ADHD, asthma, birth weight, and BMI). The aim of the current...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2010.07.020
更新日期:2011-03-01 00:00:00
abstract::We present a case of violent sleep-related behaviour in a patient with narcolepsy with cataplexy (NC) and REM sleep behaviour disorder (RBD), causing injuries to his wife that resulted in charge of assault, followed by a divorce case. This observation pinpoints that RBD in NC can arise early in a patient's life and th...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2010.07.001
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Patients with obstructive sleep apnea syndrome (OSAS) are known to have an increased risk for motor vehicle crashes. They suffer from sleep-related respiratory abnormality causing repetitive arousal leading to daytime sleepiness. In turn, it has been demonstrated that sleepiness can impair human psychomotor ...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2008.11.005
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:It is now recognized that the vast majority of individuals with typical RBD will develop a synucleinopathy; usually 11-16 years after symptom onset. Parasomnia Overlap Disorder (POD) with adolescent-onset dream enactment behavior with phenoconversion to neurodegenerative disease after a long latency has not ...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.01.041
更新日期:2019-05-01 00:00:00