Abstract：
:Over the past 5 years, Diffusion Tensor Imaging (DTI) has begun to provide new evidence about the effects of prenatal alcohol exposure on white matter development. DTI, which examines microstructural tissue integrity, is sensitive to more subtle white matter abnormalities than traditional volumetric MRI methods. Thus far, the available DTI data suggest that white matter microstructural abnormalities fall on a continuum of severity in Fetal Alcohol Spectrum Disorder (FASD). Abnormalities are prominent in the corpus callosum, but also evident in major anterior-posterior fiber bundles, corticospinal tracts, and cerebellum. These subtle abnormalities are correlated with neurocognitive deficits, especially in processing speed, non-verbal ability, and executive functioning. Future studies using larger samples, increasingly sophisticated DTI methods, and additional functional MRI connectivity measures will better characterize the full range of abnormalities in FASD. Ultimately, these measures may serve as indices of change in future longitudinal studies and in studies of interventions for FASD.
journal_name
Neuropsychol Revjournal_title
Neuropsychology reviewauthors
Wozniak JR,Muetzel RLdoi
10.1007/s11065-011-9162-1subject
Has Abstractpub_date
2011-06-01 00:00:00pages
133-47issue
2eissn
1040-7308issn
1573-6660journal_volume
21pub_type
杂志文章,评审abstract：:Apraxia is one of the cognitive deficits that characterizes Alzheimer's disease. Despite its prevalence and relevance to diagnosing Alzheimer's disease, this topic has received little attention and is without comprehensive review. The review herein is aimed to fill this gap by first presenting an overview of the impai...
journal_title：Neuropsychology review
pub_type： 杂志文章,评审
doi：10.1007/s11065-013-9235-4
更新日期：2013-09-01 00:00:00
abstract：:The mandate for evidence-based practice has prompted careful consideration of the weight of the scientific evidence regarding the therapeutic value of various clinical treatments. In the field of aphasia, a large number of single-subject research studies have been conducted, providing clinical outcome data that are po...
journal_title：Neuropsychology review
pub_type： 杂志文章,评审
doi：10.1007/s11065-006-9013-7
更新日期：2006-12-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
doi：10.1007/s11065-019-09398-4
更新日期：2019-06-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章
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更新日期：2018-09-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
doi：10.1023/a:1025525613477
更新日期：2003-09-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,meta分析
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更新日期：2018-12-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,meta分析,评审
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更新日期：2014-06-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 历史文章,杂志文章
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更新日期：1994-12-01 00:00:00
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journal_title：Neuropsychology review
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journal_title：Neuropsychology review
pub_type： 杂志文章
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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journal_title：Neuropsychology review
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更新日期：2001-09-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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journal_title：Neuropsychology review
pub_type： 传,历史文章,杂志文章
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更新日期：1994-03-01 00:00:00
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journal_title：Neuropsychology review
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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更新日期：2010-12-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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更新日期：1998-03-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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更新日期：1998-12-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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更新日期：2014-12-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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更新日期：2000-09-01 00:00:00
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journal_title：Neuropsychology review
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更新日期：2020-09-01 00:00:00
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journal_title：Neuropsychology review
pub_type： 杂志文章,评审
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