Abstract:
:Accumulating evidence over the past decade suggests that semantic deficits represent a consistent feature of Mild Cognitive Impairment (MCI). A meta-analysis was performed to examine if semantic deficits are consistently found in patients with MCI. Studies meeting all inclusion criteria were selected for the current meta-analysis. An effect size and a weight were calculated for each study. A random effect model was performed to assess the overall difference in semantic performances between MCI patients and healthy subjects. 22 studies (476 healthy participants, 476 MCI patients, mean Mini Mental Status Examination of the MCI patients: 27.05 ± 0.58) were included in the meta-analysis. Results indicate that MCI patients systematically performed significantly worse than healthy matched controls in terms of overall semantic performance (mean effect size of 1.02; 95% CI [0.80; 1.24]). Semantic deficits are a key feature of MCI. Semantic tests should be incorporated in routine clinical assessments.
journal_name
Neuropsychol Revjournal_title
Neuropsychology reviewauthors
Joubert S,Gardy L,Didic M,Rouleau I,Barbeau EJdoi
10.1007/s11065-020-09453-5subject
Has Abstractpub_date
2020-08-19 00:00:00eissn
1040-7308issn
1573-6660pii
10.1007/s11065-020-09453-5pub_type
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