Adolescent brain development and the risk for alcohol and other drug problems.

Abstract:

:Dynamic changes in neurochemistry, fiber architecture, and tissue composition occur in the adolescent brain. The course of these maturational processes is being charted with greater specificity, owing to advances in neuroimaging and indicate grey matter volume reductions and protracted development of white matter in regions known to support complex cognition and behavior. Though fronto-subcortical circuitry development is notable during adolescence, asynchronous maturation of prefrontal and limbic systems may render youth more vulnerable to risky behaviors such as substance use. Indeed, binge-pattern alcohol consumption and comorbid marijuana use are common among adolescents, and are associated with neural consequences. This review summarizes the unique characteristics of adolescent brain development, particularly aspects that predispose individuals to reward seeking and risky choices during this phase of life, and discusses the influence of substance use on neuromaturation. Together, findings in this arena underscore the importance of refined research and programming efforts in adolescent health and interventional needs.

journal_name

Neuropsychol Rev

journal_title

Neuropsychology review

authors

Bava S,Tapert SF

doi

10.1007/s11065-010-9146-6

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

398-413

issue

4

eissn

1040-7308

issn

1573-6660

journal_volume

20

pub_type

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