Abstract:
:Dynamic changes in neurochemistry, fiber architecture, and tissue composition occur in the adolescent brain. The course of these maturational processes is being charted with greater specificity, owing to advances in neuroimaging and indicate grey matter volume reductions and protracted development of white matter in regions known to support complex cognition and behavior. Though fronto-subcortical circuitry development is notable during adolescence, asynchronous maturation of prefrontal and limbic systems may render youth more vulnerable to risky behaviors such as substance use. Indeed, binge-pattern alcohol consumption and comorbid marijuana use are common among adolescents, and are associated with neural consequences. This review summarizes the unique characteristics of adolescent brain development, particularly aspects that predispose individuals to reward seeking and risky choices during this phase of life, and discusses the influence of substance use on neuromaturation. Together, findings in this arena underscore the importance of refined research and programming efforts in adolescent health and interventional needs.
journal_name
Neuropsychol Revjournal_title
Neuropsychology reviewauthors
Bava S,Tapert SFdoi
10.1007/s11065-010-9146-6subject
Has Abstractpub_date
2010-12-01 00:00:00pages
398-413issue
4eissn
1040-7308issn
1573-6660journal_volume
20pub_type
杂志文章,评审abstract::A wealth of empirical evidence is accumulating on the genetic mediation of brain structure phenotypes. This comes from twin studies that assess heritability and genetic covariance between traits, candidate gene associations, and genome-wide association studies (GWAS) that can identify specific genetic variants. Here w...
journal_title:Neuropsychology review
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doi:10.1007/s11065-015-9281-1
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journal_title:Neuropsychology review
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journal_title:Neuropsychology review
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journal_title:Neuropsychology review
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journal_title:Neuropsychology review
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journal_title:Neuropsychology review
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journal_title:Neuropsychology review
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journal_title:Neuropsychology review
pub_type: 杂志文章,评审
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journal_title:Neuropsychology review
pub_type: 传,历史文章,杂志文章
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journal_title:Neuropsychology review
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journal_title:Neuropsychology review
pub_type: 杂志文章,评审
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