Abstract：
OBJECTIVE:To measure IVF effectiveness, which is defined as the cumulative incidence of live delivery over real time in women after commencing IVF treatment. DESIGN:Population-based retrospective cohort study. SETTING:IVF clinics in Western Australia (WA). PATIENT(S):All women ages 20-44 years inclusive at start of treatment, commencing IVF in 1982-1992 and 1993-2002 at clinics in WA (n = 8,275). INTERVENTION(S):Data on IVF cycles were extracted from hospital records and a statutory reproductive technology register and linked to records of births. MAIN OUTCOME MEASURE(S):Cumulative incidence of an IVF-attributed live delivery and cumulative incidence of an IVF-attributed or IVF treatment-independent live delivery. RESULT(S):IVF effectiveness in the 1993-2002 cohort was 47% overall. It was highest in women ages 20-29 years at the start of treatment, measuring 58%; and 79% with the inclusion of IVF treatment-independent deliveries, and declined to 22% and 33%, respectively, in women ages 40-44 years. Couples underwent, on average, only three cycles, even though the cumulative probability of a live delivery increased with each successive cycle for at least the first five cycles. CONCLUSION(S):IVF effectiveness could be improved if women, particularly those over 35, underwent more cycles.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Stewart LM,Holman CD,Hart R,Finn J,Mai Q,Preen DBdoi
10.1016/j.fertnstert.2011.01.130subject
Has Abstractpub_date
2011-04-01 00:00:00pages
1677-83issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(11)00164-6journal_volume
95pub_type
杂志文章abstract：OBJECTIVE:To determine whether the presence of a Y microdeletion confers any adverse effects on in vitro fertilization or intracytoplasmic sperm injection (IVF/ICSI) outcome. DESIGN:Retrospective case-control study. SETTING:Academic infertility center. PATIENT(S):A total of 17 patients with Y microdeletions who atte...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.06.030
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:To define a therapeutic strategy adapted to acute urine retention resulting from uterine incarceration in early pregnancy. DESIGN:Case report and review of the literature. SETTING:University hospital. PATIENT(S):Two cases of acute urine retention induced by severe fibroid incarceration in first trimester. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2007.10.008
更新日期：2008-10-01 00:00:00
abstract：:Women with a BRCA mutation have unique concerns about childbearing and future fertility. In a focus group conducted among unaffected carriers, the majority of women held positive attitudes toward preimplantation genetic diagnosis to reduce transmission to future offspring and further identified unmet needs for educati...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.03.064
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To investigate whether BRCA carriers with and without malignancy have decreased ovarian reserve at baseline compared with BRCA noncarriers. DESIGN:Retrospective cohort study. SETTING:Academic medical center. PATIENT(S):Seven-hundred and ninety-five oocyte cryopreservation patients, comprising BRCA carriers...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2018.10.014
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:To report a case of monochorionic, diamniotic twin pregnancy diagnosed at 6 weeks of pregnancy with three-dimensional (3D) transvaginal sonography and to discuss the use of this diagnostic method in the evaluation of multifetal pregnancy in the first trimester. DESIGN:Case report. SETTING:University-based I...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00132-6
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVE:To examine the effect of supraphysiologic doses of testosterone (T) on plasma total homocysteine (tHcy) concentrations in patients with Klinefelter's syndrome (KS). DESIGN:Prospective clinical study. SETTING:University hospital. PATIENT(S):Thirty-two newly diagnosed male patients with KS, and 20 healthy, v...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.11.029
更新日期：2004-05-01 00:00:00
abstract：:A prospective randomized study of 243 embryo transfers revealed that the use of blastocysts in assisted reproductive technology is not more effective than the use of day 2 and day 3 embryos. ...
journal_title：Fertility and sterility
pub_type： 临床试验,信件,随机对照试验
doi：10.1016/j.fertnstert.2003.07.016
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:To evaluate if apoptosis occurs in human germ cells between 19 and 33 gestational weeks (GW). DESIGN:Human fetal ovaries were obtained from aborted fetuses aged 19-33 GW. SETTING:Rabin Medical Center, a major tertiary care and referral center. PATIENT(S):Twenty-seven women undergoing pregnancy termination....
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)03218-1
更新日期：2002-08-01 00:00:00
abstract：OBJECTIVE:To assess whether oral administration of 100 mg of nimesulide reduces pain during or after a hysterosalpingography (HSG) performed with disposable balloon catheters. DESIGN:Prospective, randomized, placebo-controlled study. SETTING:Reproductive Centre, Department of Obstetrics and Gynaecology, University of...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2007.07.1302
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To analyze information on assisted reproductive technology (ART) performed worldwide and trends in outcomes over successive years. DESIGN:Cross-sectional survey on access, effectiveness, and safety of ART procedures performed in 53 countries during 2005. SETTING:A total of 2,973 clinics from national and re...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.10.005
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To assess the relevant factors affecting patients' decision when choosing a clinic for private, self-funded IVF treatment. DESIGN:Prospective anonymous closed questionnaires. SETTING:Single tertiary-care private IVF center. PATIENT(S):New patients attending primary consultation in a period of 7 months from...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)01751-4
更新日期：2001-05-01 00:00:00
abstract：:Many will agree that the use of laparoscopy to diagnose and potientially treat endometriosis in patients who suffer from infertility has been superseded by IVF and sometimes oocyte donation, especially in older patients. The findings of our study add another dimension to management of endometriosis in the setting of i...
journal_title：Fertility and sterility
pub_type： 评论,杂志文章,评审
doi：10.1016/j.fertnstert.2005.06.033
更新日期：2005-12-01 00:00:00
abstract：:Survey results demonstrate that the majority of fertility clinics in California are willing to care for couples affected by human immunodeficiency virus (HIV) if legal restrictions are removed. In response to scientific advances and evolving clinical standards, California reversed the limitations placed on the provisi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.09.013
更新日期：2009-04-01 00:00:00
abstract：:In two patients with apparent PTO, as diagnosed by HSG and laparoscopy, tubal patency was restored by hysteroscopic cannulation of the tubal ostia, followed by direct lavage. Tubal resection and reanastomosis/reimplantation may not be necessary for all patients with apparent PTO. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1987-09-01 00:00:00
abstract：:Many women now choose to develop their careers before having children. Thus, it is becoming increasingly important to assess a woman's potential for extended fertility and to understand the health consequences of having children at a late age. In particular, there is a striking positive correlation between extended fe...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2015.02.008
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To evaluate which clinical characteristics influence early maternal β-human chorionic gonadotropin (hCG) and progesterone levels in in vitro fertilization (IVF) pregnancies. DESIGN:Retrospective cohort analysis. SETTING:Academic medical center. PATIENT(S):Women with a live birth after single-blastocyst emb...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2018.08.047
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To determine the effect of sodium alginate encapsulation of rodent embryos on in vitro embryonic cleavage rates, implantation rates, and livebirth rates, and to find the in vivo degradation time for the capsules. DESIGN:Studies were conducted using both CB6F1 mice and Golden Syrian hamsters. RESULTS:Capsule...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55814-2
更新日期：1993-03-01 00:00:00
abstract：OBJECTIVE:To examine selection criteria for ovarian reserve screening. DESIGN:Retrospective study. PATIENTS:Two hundred nineteen women underwent testing for ovarian reserve for woman's age > 35 years, any age with unexplained infertility, one ovary, or a poor response to hMG. INTERVENTIONS:Clomiphene citrate challen...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58386-1
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVE:To determine Müllerian inhibiting substance (MIS) levels in follicular fluid (FF) and sera of IVF patients. DESIGN:Prospective study. SETTING:Fertility center. PATIENT(S):Sixty-six patients: 20 with tubal factor infertility, 17 with polycystic ovary syndrome (PCOS), and 29 with endometriosis. INTERVENTION...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81417-3
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:To evaluate surgical outcome and long-term follow-up of conservative laparoscopic management of urinary tract endometriosis (UTE). DESIGN:Prospective study. SETTING:Tertiary-care university hospital. PATIENT(S):Women with laparoscopic diagnosis and histologic confirmation of urinary bladder or ureteral end...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2009.04.019
更新日期：2010-08-01 00:00:00
abstract：:Nineteen vasectomized men were followed for 21 to 42 months after surgery, and their sera were tested for the presence of HL-A lymphocytoxic antibodies. In a previous study, the sera of two of these men had shown a definite increase in serum reactivity 6 to 12 months after surgery. Only one of the nineteen tested in t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42494-5
更新日期：1977-04-01 00:00:00
abstract：:To show that in the dysgenetic gonads of 104 Turner syndrome patients no significant difference was found regarding the expression of the genes DAX1, FOG2, GATA4, OCT4, SF1, SRY, TSPY, WT1, and STRA8 compared with controls, except for genes OCT4, SRY, and TSPY in both gonads of a patient whose chromosomal constitution...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.02.036
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To evaluate expression of interleukin-1 receptor type I in the endometrium of fertile women throughout the menstrual cycle and to investigate whether unexplained infertility may be associated with abnormal expression of IL-1 receptor type I. DESIGN:Retrospective study using immunohistochemical technique, Wes...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)01634-4
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:To assess the impact on women's reproductive outcomes of barbed sutures to repair uterine breaches during laparoscopic myomectomy compared with traditional smooth sutures. DESIGN:Retrospective, monocentric cohort study, with information on subsequent pregnancies prospectively acquired for some women. SETTIN...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.07.036
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:To compare outcome of pregnancies after intracytoplasmic sperm injection (ICSI) with those of other assisted reproductive technologies. DESIGN:Pregnancy outcomes after ICSI were followed prospectively and compared with pregnancy outcomes after IVF with fresh and frozen ETs and donor oocyte cycles. SETTING:A...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:Determine whether peritoneal macrophages from women with endometriosis-associated infertility express more inducible nitric oxide synthase (NOS2) and produce more NO than fertile controls. DESIGN:Unblinded clinical study. PATIENT(S):Nine infertile women with endometriosis and nine normal fertile women under...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)02940-5
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of the immunosuppressant tacrolimus on rejection of a transplanted uterus and on uterine expression of markers of inflammation and implantation. DESIGN:Experimental study. SETTING:University laboratory. ANIMAL(S):Female rats. INTERVENTION(S):Uteri from brown Norway rats were transp...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.11.002
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to assess which of the basal ovarian reserve markers provides the best reflection of the changes occurring in ovarian function over time (i.e., reproductive aging). DESIGN:Prospective longitudinal study. SETTING:Healthy volunteers in an academic research center. PATIENT(S):Eighty-...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.11.029
更新日期：2005-04-01 00:00:00
abstract：:Human spermatozoa were separated according to their motility by centrifuging semen on discontinuous Percoll gradients. Fractions of the gradients were examined for sperm motility, velocity, viability, morphology, bacteria, and sperm function using the hamster ova sperm penetration assay. The percentage of motile sperm...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47426-1
更新日期：1983-11-01 00:00:00
abstract：OBJECTIVE:To establish the relative frequency of aneuploidy in sperm from normal and abnormal subjects using dual color fluorescence in situ hybridization and probes for six different chromosomes. DESIGN:Semen from 33 normal males and a patient with a translocation was studied using dual color fluorescence in situ hyb...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)56896-4
更新日期：1994-08-01 00:00:00
