Abstract:
:Information about the direction of the virtual line between two positions in space (directional information) is used in many decision-making and motor tasks. We investigated how accurately directional information is processed by the brain. Subjects performed two types of task. In both tasks they sat at a table. In the first task they had to move their hand slowly and accurately from an initial position 40 cm in from of them to visually presented targets at a distance of 30 cm from the initial position (movement task). We analysed the initial movement direction. In the second task subjects had to position pointers in the direction of the targets as accurately as they could (perceptive task). We found that in the movement task the subjects started the movements to most targets in a direction that deviated consistently from the direction of the straight line between initial position and target position. The maximum deviation ranged from 5-10 degrees for the various subjects. The mean standard deviation was 4 degrees. In the perceptive task the subjects positioned the pointer in similarly deviating directions. Furthermore, we found that the maximum deviation in the pointer direction depended on the length of the pointer: the smaller the pointer, the larger the consistent deviations in the pointer direction. The shortest pointer showed deviations comparable to the deviations found in the movement task. These findings suggest that the deviations in the two tasks stem from the same source.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
de Graaf JB,Sittig AC,Denier van der Gon JJdoi
10.1007/BF00231466subject
Has Abstractpub_date
1991-01-01 00:00:00pages
434-8issue
2eissn
0014-4819issn
1432-1106journal_volume
84pub_type
杂志文章abstract::Quantitative studies were made of the distribution of labeled intracortical axons after focal injections of horseradish peroxidase (HRP) into mouse barrel cortex, in vitro. The pattern of labeled fibers was compared to that of labeled cell bodies with respect to the barrel map in layer IV. We analyzed 4 cortices with ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231244
更新日期:1990-01-01 00:00:00
abstract::Two experiments were conducted to determine the effects of conditioned circling on the concentrations of dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) within discrete regions of the striatum (STR). The first study assessed the inherent regional distributions of these compounds with ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247949
更新日期:1989-01-01 00:00:00
abstract::Enteric glia share morphological, biochemical, and functional properties with astrocytes. Thus, like astrocytes, transplantation of enteric glia into the central nervous system (CNS) might facilitate the development of the characteristics of the blood brain barrier (BBB) in endothelial cells. This study explored this ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2119-3
更新日期:2005-03-01 00:00:00
abstract::The present study was conducted to visualize the ultrastructural features of vestibular efferent boutons in the oyster toadfish, Opsanus tau. The crista ampullaris of the horizontal semicircular canal was processed for and examined by routine transmission electron microscopy. The results demonstrate that such boutons ...
journal_title:Experimental brain research
pub_type: 更正并重新发布的文章,杂志文章
doi:10.1007/s00221-004-1898-x
更新日期:2004-07-01 00:00:00
abstract::Sinusoidal translation while rotating at constant angular velocity about a vertical axis (translation while rotating, TWR) produces centripetal and translational accelerations along the direction of translation and an orthogonal Coriolis acceleration due to the translation in the rotating frame. Thus, a Coriolis accel...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2178-5
更新日期:2005-06-01 00:00:00
abstract::Extracellular recordings were made from the nucleus ambiguous in three conscious Macaca nemestrina monkeys during spontaneous vocalizations and swallows. The temporal relationship of neuronal activity to swallowing was inferred through correlation with the thyroarytenoid electromyographic (EMG) activity. Videofluorosc...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227276
更新日期:1994-01-01 00:00:00
abstract::We report the connections of cerebellar cortical lobule HVI in the rabbit. We have studied the anterograde and retrograde transport of wheatgerm-agglutinated horseradish peroxidase (WGA-HRP) following its injection into HVI to reveal efferent and afferent connections. All of the cases showed strong anterograde transpo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237024
更新日期:1985-01-01 00:00:00
abstract::Flexible and stable postural control requires adaptation to changing environmental conditions, a process which requires re-weighting of multisensory stimuli. Recent studies, as well as predictions from a computational model, have indicated a reciprocal re-weighting relationship between modalities when a sensory stimul...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3244-z
更新日期:2012-11-01 00:00:00
abstract::The effects of learning on strategy selection in the context of action imitation have been investigated in two experiments conducted with healthy individuals. It was predicted that, once learnt, meaningless actions are processed by the cognitive system as meaningful and this new representational status might influence...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-006-0395-9
更新日期:2006-08-01 00:00:00
abstract::Predicted motion (PM) tasks test the accuracy of predicting the future position of a moving target. Previous PM studies using audiovisual stimuli have suggested that observers rely primarily on visual motion cues. To clarify the role of auditory signals in predicting future positions of bimodal targets, we designed a ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2224-4
更新日期:2010-06-01 00:00:00
abstract::The phenotypic effect of the weaver mutation in the ventral midbrain of homozygous mutants is associated with the progressive loss of dopaminergic neurons. To discover whether the number of mesencephalic dopaminergic cells is altered in weaver heterozygotes (wv/+), we studied mice between 20 and 365 days of age. We co...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF02454137
更新日期:1997-01-01 00:00:00
abstract::We tested the hypothesis that frontal eye field (FEF) visual activity integrates visual information with a template of a target by examining whether a target that is not present in a search display influences the target selection in FEF. Neural activity was recorded in FEF of macaque monkeys performing visual search f...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1461-1
更新日期:2003-08-01 00:00:00
abstract::It is not evident how the small effects of the flankers of the Ebbinghaus figure on peak grip aperture (PGA) should be interpreted. One interpretation is that the flankers influence the estimated size, which in turn influences the grasp. If this interpretation is correct, then only the size-dependent aspects of the gr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2138-0
更新日期:2005-05-01 00:00:00
abstract::Autologous segments of peroneal nerve were implanted into the medulla of adult rats to induce axonal regeneration of central neurons axotomised during the grafting procedure. Grafts were inserted in the midline--where respiratory axons decussate--or laterally, either in the nucleus tractus solitarius or in the nucleus...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228412
更新日期:1994-01-01 00:00:00
abstract::The distribution, dendritic trees and axonal courses of spinally projecting cells in the dorsal column nuclei were studied after labelling by retrograde HRP transport. The region of densest distribution was at the base of the two nuclei and in the area between them, extending for about 2 mm caudally from the obex. Onl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235479
更新日期:1984-01-01 00:00:00
abstract::In four normal human subjects we measured eye movements during full-field optokinetic stimulation (10-220 deg/s) and determined the relationship among retinal-slip velocity (drum velocity minus slow-phase eye velocity), the slow-phase velocity of optokinetic nystagmus (OKN) and the initial value of the slow-phase velo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230099
更新日期:1990-01-01 00:00:00
abstract::Here, we demonstrate a systematic shift in the perceived location of a tactile stimulus on the arm toward where the eye is looking. Participants reported the perceived position of touches presented between the elbow and the wrist while maintaining eye positions at various eccentricities. The perceived location of the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1884-4
更新日期:2009-09-01 00:00:00
abstract::How the CNS deals with the issue of motor redundancy remains a central question for motor control research. Here we investigate the means by which neuromuscular and biomechanical factors interact to resolve motor redundancy in rhythmic multijoint arm movements. We used a two-df motorized robot arm to manipulate the dy...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1437-2
更新日期:2008-08-01 00:00:00
abstract::The microtubule associated tau protein becomes hyperphosphorylated in Alzheimer's disease (AD). While hyperphosphorylation promotes neurodegeneration, the cause and consequences of this abnormal modification are poorly understood. As impaired energy metabolism is an important hallmark of AD progression, we tested whet...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5341-0
更新日期:2018-11-01 00:00:00
abstract::Adequate postural control is a prerequisite for daily activities such as reaching for an object. However, knowledge on the relationship between postural adjustments and the quality of reaching movements during human ontogeny is scarce. Therefore we evaluated the development of the relationship between the kinematic fe...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-0964-6
更新日期:2007-08-01 00:00:00
abstract::Within-arm somatotopy was identified in multiple motor areas of six normal human subjects who performed a visuomotor tracking task during positron emission tomography (PET) measurement of relative cerebral blood flow (relCBF). A randomly moving target, presented on a computer monitor, was continuously followed with th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229666
更新日期:1993-01-01 00:00:00
abstract::Extracellular recordings were performed from turtle red nucleus neurons to examine their responsiveness to peripheral somatic stimulation and to study differences between rubral sensory and movement-related responses. In pentobarbital sodium-anesthetized or decerebrate turtles, red nucleus neurons could be divided int...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00242899
更新日期:1996-02-01 00:00:00
abstract::The phase of the angular vestibulo-ocular reflex (VOR) is subject to adaptive control. We had previously found that adapting the phase of the VOR also produced changes in drift on eccentric gaze-holding, implying a change in the time constant of the velocity-to-position neural integrator. Here we attempted to dissocia...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s002210050392
更新日期:1998-05-01 00:00:00
abstract::Simultaneous recordings of action potentials (APs) of multiple single motor units (MUs) were obtained in brachialis and biceps (caput breve) muscles during sinusoidally modulated isometric contractions of elbow flexor muscles and during sinusoidal flexion/extension movements in the elbow against a preload in the exten...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s002210050205
更新日期:1997-10-01 00:00:00
abstract::Aiming movements of the upper limbs can be classified either as discrete, or reciprocal, or cyclic. The control of these movements after a stroke can be affected. The aim of this experimental, cross-sectional study was to characterize the performance of these movements after the right and left hemisphere chronic strok...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05897-6
更新日期:2020-10-01 00:00:00
abstract::Although postural control requires the integration of different sensory cues, little is known about the role of attentional artifacts on the individual's ability to properly respond to postural challenges. This study investigated the effects of concomitant tasks (cognitive and postural) on the relationship between vis...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4762-x
更新日期:2016-12-01 00:00:00
abstract::Counts of callosal neurons retrogradely labeled by horseradish peroxidase (visualized using multiple substrates) were obtained in areas 17 and 18 of five kittens reared with their eyelids bilaterally sutured and of three kittens which had undergone bilateral enucleation on postnatal days 1--4. These counts were compar...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239301
更新日期:1980-01-01 00:00:00
abstract::The Attention Network Test (ANT) is a frequently used computer-based tool for measuring the three attention networks (alerting, orienting, and executive control). We examined the psychometric properties of performance on a variant of the ANT, the Attention Network Test-Interaction (ANT-I) in healthy older adults (N = ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4493-4
更新日期:2016-03-01 00:00:00
abstract::The Ca++ -dependence of the repetitive firing of neostriatal neurons was studied in an in vitro slice preparation of the rat neostriatum. Neuronal firing was evoked by injecting depolarizing currents of 100-200 ms duration. In normal conditions, the mode of firing was tonic and showed very little adaptation. The frequ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248539
更新日期:1989-01-01 00:00:00
abstract::Load perturbations were applied to the arm of human subjects under conditions where both limb segments (upper arm and forearm) were free to move. The perturbations consisted of pulses of torque 50 ms in duration and of pseudo-random sequences of such pulses. They were applied to either the forearm or the upper arm. Un...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237573
更新日期:1986-01-01 00:00:00