Adipose tissue-derived progenitors for engineering osteogenic and vasculogenic grafts.

abstract：:C6 glioma cells possess beta adrenergic receptors coupled with adenylate cyclase which can be irreversibly blocked by bromoacetylaminomethylpindolol (Br-AAM-pindolol), a beta adrenergic antagonist. With 1 microM Br-AAM-pindolol, more than 80% of beta adrenergic receptors, labeled by (3H)-dihydroalprenolol [3H)-DHA), w...

journal_title：Journal of cellular physiology

authors： Homburger V,Pantaloni C,Lucas M,Gozlan H,Bockaert J

更新日期：1984-12-01 00:00:00

abstract：:Protein sorting through vesicular compartments is highly regulated to maintain the integrity and signaling of intracellular organelles in eukaryotic cells. Sorting Nexin-2 (SNX2) is involved in protein sorting in the trans-Golgi network, endosome, and/or lysosome compartments, with loss of function leading to defect i...

journal_title：Journal of cellular physiology

authors： Abdul-Ghani M,Hartman KL,Ngsee JK

更新日期：2005-07-01 00:00:00

abstract：:Recently, ATP has gained much interest as an extracellular messenger involved in the communication of calcium signals between cells. The mechanism of ATP release is, however, still a matter of debate. In the present study we investigated the possible contribution of connexin hemichannels or ion channels in the release...

journal_title：Journal of cellular physiology

authors： Braet K,Aspeslagh S,Vandamme W,Willecke K,Martin PE,Evans WH,Leybaert L

更新日期：2003-11-01 00:00:00

abstract：:Spinal cord injury (SCI) is a public health problem in the world. The SCI usually triggers an excessive inflammatory response that brings about a secondary tissue wreck leading to further cellular and organ dysfunction. Hence, there is great potential of reducing inflammation for therapeutic strategies of SCI. In this...

journal_title：Journal of cellular physiology

authors： Su Y,Zong S,Wei C,Song F,Feng H,Qin A,Lian Z,Fu F,Shao S,Fang F,Wu T,Xu J,Liu Q,Zhao J

更新日期：2019-08-01 00:00:00

abstract：:Pulmonary fibrosis is a potentially fatal consequence of treatments for malignancy and is an increasing problem in bone marrow transplant patients and in cases of allogenic lung transplant. The fibrotic response is characterized by increases in lung fibroblast number and collagen synthesis. This laboratory previously ...

journal_title：Journal of cellular physiology

authors： Sempowski GD,Derdak S,Phipps RP

更新日期：1996-05-01 00:00:00

abstract：:Cell adhesion receptors, referred to as integrins, are recognized as key regulators of cellular processes including growth and differentiation. Integrins communicate with growth factor receptors (GFRs) to control specific cellular responses to stimuli originating in the extracellular environment. In this article, we r...

journal_title：Journal of cellular physiology

authors： Alam N,Goel HL,Zarif MJ,Butterfield JE,Perkins HM,Sansoucy BG,Sawyer TK,Languino LR

更新日期：2007-12-01 00:00:00

abstract：:BAG3 protein, a member of the BAG co-chaperones family, sustains cell survival in a variety of normal and neoplastic cell types, via its interaction with a variety of partners, such as the heat shock protein (HSP) 70, Bcl-2, Raf-1 and others. Expression of BAG3 is induced by some stressful stimuli, such as heat shock,...

journal_title：Journal of cellular physiology

authors： Du ZX,Zhang HY,Meng X,Gao YY,Zou RL,Liu BQ,Guan Y,Wang HQ

更新日期：2009-03-01 00:00:00

abstract：:To test the hypothesis that football training would be accompanied by physiological adaptations and hormonal changes, we analyzed the effects of a whole football season on physical fitness and hormonal concentrations in youth football players. Male football players (n = 29, age 16.51 ± 0.7 years) in a regional profess...

journal_title：Journal of cellular physiology

authors： Muscella A,Vetrugno C,Spedicato M,Stefàno E,Marsigliante S

更新日期：2019-11-01 00:00:00

abstract：:Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is one of the most important challenges in medicine. Improving therapeutic outcomes from cancer therapy is necessary for increasing patients' survival and quality of life. Adjuvant therapy using various types of antibodies or immunomo...

journal_title：Journal of cellular physiology

authors： Mortezaee K,Salehi E,Mirtavoos-Mahyari H,Motevaseli E,Najafi M,Farhood B,Rosengren RJ,Sahebkar A

更新日期：2019-08-01 00:00:00

abstract：:Inhibition of the gap-filling, polymerizing step of excision repair by 1-beta-D-arabinofuranosylcytosine (ara-C) after irradiation with ultraviolet light in human diploid fibroblasts resulted in the formation of persistent DNA strand breaks in G1, G2, and plateau phase cells, but not in S phase cells. Addition of hydr...

journal_title：Journal of cellular physiology

authors： Cleaver JE

更新日期：1981-08-01 00:00:00

abstract：:The advent of high throughput gene expression profiling, from microarrays to sequence based assays has yielded vast insight into the biology of tumors. New technologies are constantly being unveiled which promise to generate more accurate maps of tumor gene deregulation, and demand the development of new strategies in...

journal_title：Journal of cellular physiology

authors： Coe BP,Chari R,Lockwood WW,Lam WL

更新日期：2008-12-01 00:00:00

abstract：:Atherothrombotic cardiovascular disease is a major cause of mortality throughout the world. Platelet activation and aggregation play a central role in hemostasis and thrombosis. Herbal medicines have been traditionally used in the management of cardiovascular disease and can help in modifying its progression, particul...

journal_title：Journal of cellular physiology

authors： Keihanian F,Saeidinia A,Bagheri RK,Johnston TP,Sahebkar A

更新日期：2018-06-01 00:00:00

abstract：:Focal adhesion kinase (FAK), MAP kinases and the nuclear transcription factor Elk-1 have been reported to be implicated in the same cellular processes, however, their direct or indirect interaction and potential function(s) has not been documented. Here, we explored the association of FAK with Elk-1, the implication o...

journal_title：Journal of cellular physiology

authors： Mamali I,Kotsantis P,Lampropoulou M,Marmaras VJ

更新日期：2008-07-01 00:00:00

abstract：:Bethanechol, a muscarinic agonist, inhibits the initial rate of amiloride-sensitive Na uptake by intact mucosa of avian small intestine as well as by isolated chicken villus enterocytes, an effect that is maximal at 90 seconds and reverses by 6 minutes. Bethanechol similarly decreases intracellular pH in isolated cell...

journal_title：Journal of cellular physiology

authors： Musch MW,Drabik-Arvans D,Rao MC,Chang EB

更新日期：1992-08-01 00:00:00

abstract：:Interleukin (IL)-18 is a pro-inflammatory cytokine belonging to the IL-1 family, first identified for its interferon-γ-inducing properties. IL-18 regulates both T helper (Th) 1 and Th2 responses. It acts synergistically with IL-12 in the Th1 paradigm, whereas with IL-2 and without IL-12 it can induce Th2 cytokine prod...

journal_title：Journal of cellular physiology

authors： Vecchié A,Bonaventura A,Toldo S,Dagna L,Dinarello CA,Abbate A

更新日期：2021-03-01 00:00:00

abstract：:Cell-extracellular matrix interaction plays a major role in maintaining the structural integrity of connective tissues and sensing changes in the biomechanical environment of cells. Collagen VI is a widely expressed non-fibrillar collagen, which regulates tissues homeostasis. The objective of the present investigation...

journal_title：Journal of cellular physiology

authors： Sardone F,Traina F,Tagliavini F,Pellegrini C,Merlini L,Squarzoni S,Santi S,Neri S,Faldini C,Maraldi N,Sabatelli P

更新日期：2014-07-01 00:00:00

abstract：:Lung cancer (LC) is the leading cause of cancer-related deaths all over the world, among both men and women, with an incidence of over 200,000 new cases per year coupled with a very high mortality rate. LC comprises of two major clinicopathological categories: small-cell (SCLC) and nonsmall-cell lung carcinoma (NSCLC)...

journal_title：Journal of cellular physiology

authors： Uddin A,Chakraborty S

更新日期：2018-04-20 00:00:00

abstract：:Transient receptor potential vanilloid 4 (TRPV4) channels are mechanosensitive ion channels that regulate systemic endothelial cell (EC) functions such as vasodilation, permeability, and angiogenesis. TRPV4 is expressed in retinal ganglion cells, Müller glia, pigment epithelium, microvascular ECs, and modulates cell v...

journal_title：Journal of cellular physiology

authors： Cappelli HC,Guarino BD,Kanugula AK,Adapala RK,Perera V,Smith MA,Paruchuri S,Thodeti CK

更新日期：2020-10-20 00:00:00

abstract：:Suramin is an anti-cancer drug which induces the differentiation of the human colon cancer clone HT29-D4. Yet chronic suramin treatment of these cells eventually leads to a marked disturbance of the lysosomal system, which consists in an accumulation of hypertrophied autophagic vacuoles and the occurrence of lamellate...

journal_title：Journal of cellular physiology

authors： Baghdiguian S,Verrier B,Marvaldi J,Fantini J

更新日期：1992-01-01 00:00:00

abstract：:Derivation of insulin producing cells (IPCs) from embryonic stem (ES) cells provides a potentially innovative form of treatment for type 1 diabetes. Here, we discuss the current state of the art, unique challenges, and future directions on generating IPCs. ...

journal_title：Journal of cellular physiology

authors： Raikwar SP,Zavazava N

更新日期：2009-02-01 00:00:00

abstract：:The signaling pathways that stimulate glucose uptake in response to muscle contraction are not well defined. Recently, we showed that carbachol, an acetylcholine analog, stimulates contraction of C2C12 myotube cultures and the rapid arrival of myc-epitope tagged GLUT4 glucose transporters at the cell surface. Here, we...

journal_title：Journal of cellular physiology

authors： Niu W,Bilan PJ,Yu J,Gao J,Boguslavsky S,Schertzer JD,Chu G,Yao Z,Klip A

更新日期：2011-01-01 00:00:00

abstract：:Ménière's disease (MD) is a disorder of the inner ear characterized by an insidious onset and aspecific symptoms, such as dizziness, vertigo, tinnitus, and hearing loss, that may become very debilitating. The presence of endolymphatic hydrops is a common feature in MD patients, but the pathophysiology is still largely...

journal_title：Journal of cellular physiology

authors： Chiarella G,Saccomanno M,Scumaci D,Gaspari M,Faniello MC,Quaresima B,Di Domenico M,Ricciardi C,Petrolo C,Cassandro C,Costanzo FS,Cuda G,Cassandro E

更新日期：2012-01-01 00:00:00

abstract：:Development and improvement of in vitro culture system supporting self-renewal and unlimited proliferation of porcine pluripotent stem cells (pPSCs) is an indispensable process for the naïve pPSCs establishment. In this study, we modified the previous culture system and attempted to develop a novel chemically defined ...

journal_title：Journal of cellular physiology

authors： Zhang X,Xue B,Li Y,Wei R,Yu Z,Jin J,Zhang Y,Liu Z

更新日期：2019-01-30 00:00:00

abstract：:Sleep-disordered breathing with recurrent apnea (periodic cessation of breathing) results in chronic intermittent hypoxia (IH), which leads to cardiovascular and respiratory pathology. Molecular mechanisms underlying IH-evoked cardio-respiratory co-morbidities have not been delineated. Mice with heterozygous deficienc...

journal_title：Journal of cellular physiology

authors： Yuan G,Nanduri J,Khan S,Semenza GL,Prabhakar NR

更新日期：2008-12-01 00:00:00

abstract：:Cells of rat parotid glands were maximally stimulated to initiate DNA synthesis by injecting into the animal a single dose of 25 to 150 mg of isoproterenol/kg of body weight. During the 18- to 21-hr prereplicative period following injection of the highest dose of the drug, there were two predominant and transient redi...

journal_title：Journal of cellular physiology

authors： Campos Gonzales R,Whitfield JF,Boynton AL,MacManus JP,Rixon RH

更新日期：1984-03-01 00:00:00

abstract：:The vagina provides a characteristic low-Na+ and low-pH fluid microenvironment that is considered generally protective. Previous studies have shown that various types of epithelial cells harbor the capacity of intracellular pH (pHi) regulation. However, it remains elusive whether vaginal epithelium could actively regu...

journal_title：Journal of cellular physiology

authors： Zhang YL,Feng JC,Ke LJ,Xu JW,Huang ZX,Huang J,Zhu YX,Zhou WL

更新日期：2019-01-29 00:00:00

abstract：:Expression of Runx2/p57 is a hallmark of the osteoblast-lineage identity. Although several regulators that control the expression of Runx2/p57 during osteoblast-lineage commitment have been identified, the epigenetic mechanisms that sustain this expression in differentiated osteoblasts remain to be completely determin...

journal_title：Journal of cellular physiology

authors： Rojas A,Sepulveda H,Henriquez B,Aguilar R,Opazo T,Nardocci G,Bustos F,Lian JB,Stein JL,Stein GS,van Zundert B,van Wijnen AJ,Allende ML,Montecino M

更新日期：2019-05-01 00:00:00

abstract：:Activation of hepatic progenitor cells (HPCs) is commonly observed in chronic liver disease and Wnt/β-catenin signaling plays a crucial role in the expansion of HPCs. However, the molecular mechanisms that regulate the activation of Wnt/β-catenin signaling in the liver, especially in HPCs, remain largely elusive. Here...

journal_title：Journal of cellular physiology

authors： Ding ZY,Liang HF,Jin GN,Chen WX,Wang W,Datta PK,Zhang MZ,Zhang B,Chen XP

更新日期：2014-05-01 00:00:00

abstract：:We have previously isolated 3T3 cell variants unable to respond to specific mitogens. In this report we analyze the dominant and/or recessive nature of these variants. Two independently isolated EGF nonproliferative variants are unable to bind EGF. Hybrids between 3T3R5 cells (thymidine kinase deficient, ouabain-resis...

journal_title：Journal of cellular physiology

authors： Terwilliger E,Herschman HR

更新日期：1985-06-01 00:00:00

abstract：:The study was conducted on human leukemia (K 562) cells to characterize the mechanisms implicated in the regulation of the polyamine spermidine (Spd) transport process. The antagonists of calmodulin, trifluoperazine (TFP), W-7 (N-[6-aminohexyl]-5-chloro-1-naphthelenesulfonamide), or mellitin inhibited significantly po...

journal_title：Journal of cellular physiology

authors： Khan NA,Sezan A,Quemener V,Moulinoux JP

更新日期：1993-12-01 00:00:00