A comparison of hepatocyte cytotoxic mechanisms for thallium (I) and thallium (III).

abstract：:Toxins in cyanobacteria are a recognized risk in the treatment of drinking-water treatment. Cyanotoxins can occur in two modifications: cell bound and dissolved in water. The process of toxin release may occur naturally, but it also may be induced through the processes of drinking-water treatment. Both causes of relea...

journal_title：Environmental toxicology

authors： Schmidt W,Willmitzer H,Bornmann K,Pietsch J

更新日期：2002-01-01 00:00:00

abstract：:Environmental stress factors may be responsible for biological changes in living species that are able to overcome deleterious effects depending on their detoxifying capacities. Defense systems present in every living species are involved in elimination of reactive chemical species of endogenous or exogenous origin, n...

journal_title：Environmental toxicology

authors： Vasseur P,Leguille C

更新日期：2004-08-01 00:00:00

abstract：:Domestic exposure to biomass smoke represents the second cause of chronic obstructive lung disease. Previous studies have shown that exposure of guinea pigs to wood smoke is capable of generating oxidative stress in lung tissue, and this may involve a failure at a mitochondrial level, given its close relation with the...

journal_title：Environmental toxicology

authors： Granados-Castro LF,Rodríguez-Rangel DS,Montaño M,Ramos C,Pedraza-Chaverri J

更新日期：2015-04-01 00:00:00

abstract：:Patulin is a mold toxin secreted mainly by fungi of the Penicillium species. Exposure generally results from consumption of moldy fruits and fruit products. Since recent studies identified mold exposure as a risk factor for allergic diseases, we examined the effects of patulin on human peripheral blood mononuclear cel...

journal_title：Environmental toxicology

authors： Luft P,Oostingh GJ,Gruijthuijsen Y,Horejs-Hoeck J,Lehmann I,Duschl A

更新日期：2008-02-01 00:00:00

abstract：:The 8-hydroxy-2'-deoxyguanosine (8-OHdG), an oxidized nucleoside of DNA, not only is a widely used biomarker for the measurement of endogenous oxidative DNA damage, but might also be a risk factor for many diseases including cancer. Elevated level of urinary 8-OHdG has been detected in patients with various malignanci...

journal_title：Environmental toxicology

authors： Yang Y,Tian Y,Yan C,Jin X,Tang J,Shen X

更新日期：2009-10-01 00:00:00

abstract：:Nonsmall cell lung cancer (NSCLC) is the most common type of lung cancer with a high mortality rate and still remains a therapeutic challenge. A strategy for targeting NSCLC is to identify agents that are effective against NSCLC cells while sparing normal cells. Dihydromyricetin (DHM) is the major flavonoid component ...

journal_title：Environmental toxicology

authors： Kao SJ,Lee WJ,Chang JH,Chow JM,Chung CL,Hung WY,Chien MH

更新日期：2017-04-01 00:00:00

abstract：:The toxicity of petroleum hydrocarbons to marine aquatic organisms has been widely investigated; however, the effects on freshwater environments have largely been ignored. Selected biomarkers were measured in a freshwater species, the crimson-spotted rainbowfish (Melanotaenia fluviatilis). Fish were exposed to either ...

journal_title：Environmental toxicology

authors： Pollino CA,Holdway DA

更新日期：2003-02-01 00:00:00

abstract：:Hydroponics studies were conducted to investigate the antioxidant adaptations, ascorbate and glutathione metabolism in hyperaccumulating ecotype of Sedum alfredii (HE) exposed to high Cd environment, when compared with its nonhyperaccumulating ecotype (NHE). Exposure to Cd induced a burst of oxidative stress in both e...

journal_title：Environmental toxicology

authors： Jin X,Yang X,Mahmood Q,Islam E,Liu D,Li H

更新日期：2008-08-01 00:00:00

abstract：:Chronic inhalation bioassays in rodents are used to assess pulmonary carcinogenicity for purposes of hazard identification and potentially for risk characterization. Numerous studies have been confirmed that exposure to titanium dioxide nanoparticles (TiO2 NPs) may result in chronic pulmonary inflammation in both mice...

journal_title：Environmental toxicology

authors： Hong F,Ji L,Zhou Y,Wang L

更新日期：2017-05-01 00:00:00

abstract：:Bisphenol AF (BPAF) has been shown to inhibit testicular steroidogenesis in male rats. However, the precise mechanisms related to the toxic effects of BPAF on reproduction remain poorly understood. In the present study, a mouse Leydig tumor cell line (mLTC-1) was used as a model to investigate the mechanism of steroid...

journal_title：Environmental toxicology

authors： Feng Y,Shi J,Jiao Z,Duan H,Shao B

更新日期：2018-06-01 00:00:00

abstract：:Particulate matter 2.5 (PM2.5)-induced pulmonary inflammation has become a public concern in recent years. In which, the activation of the NLRP3/caspase-1 pathway was closely related to the inflammatory response of various diseases. However, the promotion effect of the NLRP3/caspase-1 pathway on PM2.5-induced pulmonar...

journal_title：Environmental toxicology

authors： Jia H,Liu Y,Guo D,He W,Zhao L,Xia S

更新日期：2020-09-30 00:00:00

abstract：:Cantharidin is one of the major compounds from mylabris and it has cytotoxic effects in many different types of human cancer cells. Previously, we found that cantharidin induced cell death through cell cycle arrest and apoptosis induction in human lung cancer NCI-H460 cells. However, cantharidin-affected DNA damage, r...

journal_title：Environmental toxicology

authors： Hsia TC,Lin JH,Hsu SC,Tang NY,Lu HF,Wu SH,Lin JG,Chung JG

更新日期：2015-09-01 00:00:00

abstract：:Colorectal cancer (CC) is an important human malignancy with high cancer related death worldwide. The chemotherapy using doxorubicin hydrochloride is one of the most common cancer therapeutic methods. However, drug resistance lowers the treatment efficacy in CC patients. The combination therapies seem to be more promi...

journal_title：Environmental toxicology

authors： Jadid MFS,Aghaei E,Taheri E,Seyyedsani N,Chavoshi R,Abbasi S,Khorrami A,Goleij P,Hajazimian S,Taefehshokr S,Isazadeh A,Shanehbandi D

更新日期：2021-01-28 00:00:00

abstract：:The freshwater crabs Sinopotamon henanense were exposed to different concentrations of waterborne cadmium (Cd). The relationship between tissue-specific Cd accumulation and metallothionein (MT) induction was investigated using the Cd saturation assay and atomic absorption spectrophotometry method. The results showed t...

journal_title：Environmental toxicology

authors： Ma W,Wang L,He Y,Yan Y

更新日期：2008-06-01 00:00:00

abstract：:Intake of arsenic (As) via drinking water has been a serious threat to global public health. Though there are numerous reports of As neurotoxicity, its pathogenesis mechanisms remain vague especially its chronic effects on metabolic network. Hippocampus is a renowned area in relation to learning and memory, whilst rec...

journal_title：Environmental toxicology

authors： Mo TT,Dai H,Du H,Zhang RY,Chai KP,An Y,Chen JJ,Wang JK,Chen ZJ,Chen CZ,Jiang XJ,Tang R,Wang LP,Tan Q,Tang P,Miao XY,Meng P,Zhang LB,Cheng SQ,Peng B,Tu BJ,Han TL,Xia YY,Baker PN

更新日期：2019-02-01 00:00:00

abstract：:Ionic liquids (ILs) are widely used as reaction media in various commercial applications. Many reports have indicated that most ILs are poorly decomposed by microorganisms and are toxic to aquatic organisms. In this study, differential gene expression profiling was conducted using a suppression subtraction hybridizati...

journal_title：Environmental toxicology

authors： Nan P,Yan S,Wang Y,Du Q,Chang Z

更新日期：2017-02-01 00:00:00

abstract：:di-N-butylphthalate (DBP) is a ubiquitous environmental pollutant used for plastic coating and in the cosmetics industry. It has toxic effects on body health, especially the male reproductive system. Here, we investigated the effects of DBP on the male reproductive system of pubertal mice and explored the protective r...

journal_title：Environmental toxicology

authors： Jiang XP,Tang JY,Xu Z,Han P,Qin ZQ,Yang CD,Wang SQ,Tang M,Wang W,Qin C,Xu Y,Shen BX,Zhou WM,Zhang W

更新日期：2017-07-01 00:00:00

abstract：:Three methods of algal assays--the standard assay, microassay, and the proposed fluorescence assay--are compared from the point of view of reliability of EC50 detection, the minimum required time for the detection, sensitivity of individual measurement, i.e. at which cell density the particular assay can be used for E...

journal_title：Environmental toxicology

authors： Kvíderová J

更新日期：2010-12-01 00:00:00

abstract：:As a widely used plasticizer in industry, di-2-ethylhexylphthalate (DEHP) can cause testicular toxicity, yet little is known about the potential mechanism. In this study, DEHP exposure dramatically inhibited cellviability and induced apoptosis of mouse GC-1 spg cells. Furthermore, DEHP significantly increased the leve...

journal_title：Environmental toxicology

authors： Gan Y,Yang D,Yang S,Wang J,Wei J,Chen J

更新日期：2020-02-01 00:00:00

abstract：:Methoxychlor (MXC), an organochloride insecticide, is a potent toxicant-targeting female reproductive system and known to cause follicular atresia by inducing apoptosis within granulosa cells. Oxidative stress plays a pivotal role in apoptosis; thus, this study focuses on the ameliorative action of N-acetyl cysteine (...

journal_title：Environmental toxicology

authors： Bhardwaj JK,Saraf P

更新日期：2017-01-01 00:00:00

abstract：:Biotransformation enzymatic activities, such as the cytochrome P450 one, have been used as biomarkers for pollution assessment for a long time. Nevertheless, such biochemical tools are destructive processes, because they are performed on fish liver or total larvae homogenates. Moreover, the adaptation of this bioassay...

journal_title：Environmental toxicology

authors： Noury P,Geffard O,Tutundjian R,Garric J

更新日期：2006-08-01 00:00:00

abstract：:Aspartame is one of the most common consumed artificial sweeteners utilized in many food products and beverages. It has been indicated that long-term consumption of aspartame leads to reproductive toxicity but its mechanism is not well-clear. In this study we investigated mechanism of aspartame-induced reproductive to...

journal_title：Environmental toxicology

authors： Anbara H,Sheibani MT,Razi M,Kian M

更新日期：2021-02-01 00:00:00

abstract：:Indium, a rare earth metal characterized by high plasticity, corrosion resistance, and a low melting point, is widely used in the electronics industry, but has been reported to be an environmental pollutant and a health hazard. We designed a study to investigate the effects of subacute exposure of indium compounds on ...

journal_title：Environmental toxicology

authors： Lee KH,Chen HL,Leung CM,Chen HP,Hsu PC

更新日期：2016-01-01 00:00:00

abstract：:Lead ions (Pb(2+) ) are toxic industrial pollutants associated with chronic inflammatory diseases in humans and animals. Previously, we found that Pb(2+) ions induce COX-2 gene expression via the EGF receptor/nuclear factor-κB signal transduction pathway in epidermoid carcinoma cell line A431. In this study, to see wh...

journal_title：Environmental toxicology

authors： Tsai YT,Chang CM,Wang JY,Hou MF,Wang JM,Shiurba R,Chang WC,Chang WC

更新日期：2015-09-01 00:00:00

abstract：:Inflammation generated by environmental toxicants including pesticides could be one of the factors underlying neuronal cell damage in neurodegenerative diseases. In this study, we investigated the mechanisms by which inflammatory responses contribute to apoptosis in PC12 cells treated with diquat. We found that diquat...

journal_title：Environmental toxicology

authors： Choi SE,Park YS,Koh HC

更新日期：2018-10-01 00:00:00

abstract：:The correlation between the content of three microcystins (types LR, RR and YR) and the cell cycle of an axenic strain of Microcystis viridis, NIES-102, was investigated under conditions of high (16 mg L(-1)) and low (1.0 mg L(-1)) nitrate (NO(3)-N) concentrations. Each phase of the cell cycle was identified using a f...

journal_title：Environmental toxicology

authors： Kameyama K,Sugiura N,Inamori Y,Maekawa T

更新日期：2004-02-01 00:00:00

abstract：:Although marine and coastal environments which are contaminated with xenobiotic organic compounds often become hypoxic during the summer, the interactive effects of hypoxia and xenobiotic exposure on marine species such as teleost fishes remain poorly understood. The expression and activity of monooxygenase enzyme cyt...

journal_title：Environmental toxicology

authors： Rahman MS,Thomas P

更新日期：2018-04-01 00:00:00

abstract：:The acute toxicity of the insecticide fenitrothion was measured using four freshwater algae (Chlorella saccharophila, Chlorella vulgaris, Scenedesmus acutus, and Scenedesmus subspicatus) and one cyanobacteria (Pseudanabaena galeata). Insecticide concentrations eliciting 50% growth reduction over 96 hr (EC50) ranged fr...

journal_title：Environmental toxicology

authors： Sabater C,Carrasco JM

更新日期：2001-01-01 00:00:00

abstract：:The mycotoxin citrinin (CTN), a natural contaminant in foodstuffs and animal feeds, exerts cytotoxic and genotoxic effects on various mammalian cells. CTN causes cell injury, including apoptosis. Previous studies by our group showed that CTN triggers apoptosis in mouse embryonic stem cells, as well as embryonic develo...

journal_title：Environmental toxicology

authors： Huang YT,Lai CY,Lou SL,Yeh JM,Chan WH

更新日期：2009-08-01 00:00:00

abstract：:Lake Elphinstone is a tropical inland water body in the far north of the Fitzroy Catchment in Central Queensland, Australia, and has experienced recurrent toxic cyanoprokaryote blooms since 1997. This article reports on an examination of the environmental conditions of the lake and the concurrent cyanoprokaryote speci...

journal_title：Environmental toxicology

authors： White SH,Fabbro LD,Duivenvoorden LJ

更新日期：2003-12-01 00:00:00