Preventing hospitalization for COPD exacerbations.

abstract：:The human Herpesviridae family consists of eight members: cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus 1 and 2 (HSV-1, -2), varicella-zoster virus (VZV), and human herpesvirus 6, 7, and 8 (HHV-6, -7, -8). Lifelong latency may develop in the host with reactivation during periods of relative imm...

journal_title：Seminars in respiratory and critical care medicine

authors： Zamora MR

更新日期：2011-08-01 00:00:00

abstract：:Treatment strategies for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are evolving. Cyclophosphamide (CYC) plus corticosteroids (CSs) is the mainstay of therapy for generalized, multisystemic AAV. Historically, the combination of CYC plus CS was used for a minimum of 12 months, but concern a...

journal_title：Seminars in respiratory and critical care medicine

authors： Wang T,Weigt SS,Belperio JA,Lynch JP 3rd

更新日期：2011-06-01 00:00:00

abstract：:Mycoplasma pneumoniae infection occurs worldwide and is the most common cause of community-acquired pneumonia (CAP) in 5- to 20-year-olds. The most reliable diagnostic test is the enzyme immunoassay, which allows immunoglobulin (Ig)G and IgM titration and presents 92% sensitivity and 95% specificity on paired samples....

journal_title：Seminars in respiratory and critical care medicine

authors： Blasi F,Tarsia P,Aliberti S,Cosentini R,Allegra L

更新日期：2005-12-01 00:00:00

abstract：:Pneumocystis jiroveci remains an important fungal pathogen in a broad range of immunocompromised hosts. The natural reservoir of infection remains unknown. Pneumocystis jiroveci Pneumonia (PJP) develops via airborne transmission or reactivation of inadequately treated infection. Nosocomial clusters of infection have b...

journal_title：Seminars in respiratory and critical care medicine

authors： Fishman JA

更新日期：2020-02-01 00:00:00

abstract：:Sepsis is a common and life-threatening condition with a high mortality rate. Severe sepsis includes multiorgan dysfunction syndrome. The organ most often affected is the lung, with development of acute lung injury (ALI), which, in its most severe form, is referred to as acute respiratory distress syndrome (ARDS). Our...

journal_title：Seminars in respiratory and critical care medicine

authors： Bastarache JA,Ware LB,Bernard GR

更新日期：2006-08-01 00:00:00

abstract：:Sjögren syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic inflammation of exocrine glands and a variety of extraglandular sites. Lung involvement as defined by symptoms and either pulmonary function testing or radiographic abnormalities occurs in approximately 10 to 20% of patients. Subclinica...

journal_title：Seminars in respiratory and critical care medicine

authors： Kreider M,Highland K

更新日期：2014-04-01 00:00:00

abstract：:Tracheobronchial prostheses, known as airway stents, are used to palliate the effects of large airway obstruction. The most common types of stents in current clinical use are made of silicone or metallic wire. An ideal stent should possess several characteristics: (1) it should be easy to insert and remove, if necessa...

journal_title：Seminars in respiratory and critical care medicine

authors： Saito Y

更新日期：2004-08-01 00:00:00

abstract：:Nonneoplastic pulmonary lymphoid disorders consist of a complex spectrum of diseases for pathologists and pulmonologists alike. Advances in our understanding of these disorders in recent years have led to revisions in the classification scheme. This review summarizes the clinicoradiological and pathological features o...

journal_title：Seminars in respiratory and critical care medicine

authors： Tian X,Yi ES,Ryu JH

更新日期：2012-10-01 00:00:00

abstract：:Despite recent advances in understanding, the management of acute respiratory distress syndrome (ARDS) remains a challenging clinical problem. Optimization of gas exchange and preventing the iatrogenic propagation of lung injury are cornerstones of its clinical management. A number of novel approaches and adjuncts to ...

journal_title：Seminars in respiratory and critical care medicine

authors： Kress JP,Marini JJ

更新日期：2001-06-01 00:00:00

abstract：:Invasive fungal infections, especially candidemia and systemic candidiasis, have become a major cause of morbidity and mortality in the last few decades. This comes in parallel with the major advances made in intensive care. Patients who are critically ill, in medical or surgical ICUs are especially at risk for CANDID...

journal_title：Seminars in respiratory and critical care medicine

authors： Vazquez JA

更新日期：2010-02-01 00:00:00

abstract：:Identifying genetic determinants of pulmonary fibrosis is at an early stage of evolution. It is now well recognized that "pulmonary fibrosis" covers a broad range of lung diseases including most topically the idiopathic interstitial pneumonias that have been classified recently. Additionally, it is recognized that the...

journal_title：Seminars in respiratory and critical care medicine

authors： du Bois RM,Kangesan I,Veeraraghavan S

更新日期：2003-04-01 00:00:00

abstract：:The median age of presentation with lung cancer is 71, making the elderly the dominant subgroup. Although some elderly patients are frail, others have great physiological reserve. Geriatric assessment can clarify the specific strengths and weaknesses of older patients, improving management. This assessment should, at ...

journal_title：Seminars in respiratory and critical care medicine

authors： Weiss J,Langer C

更新日期：2013-12-01 00:00:00

abstract：:Assisted mechanical ventilation (MV) may be a favorable alternative to controlled MV at the early phase of acute respiratory distress syndrome (ARDS), since it requires less sedation, no paralysis and is associated with less hemodynamic deterioration, better distal organ perfusion, and lung protection, thus reducing t...

journal_title：Seminars in respiratory and critical care medicine

authors： Saddy F,Sutherasan Y,Rocco PR,Pelosi P

更新日期：2014-08-01 00:00:00

abstract：:The overarching goals of early sepsis management include early recognition, appropriate antibiotic therapy and source control, maintenance of hemodynamic stability, and supportive care of organ dysfunction. Despite increasing awareness of the global burden of sepsis, and general agreement on the goals of management, t...

journal_title：Seminars in respiratory and critical care medicine

authors： Moss SR,Prescott HC

更新日期：2019-10-01 00:00:00

abstract：:Respiratory samples obtained by bronchoalveolar lavage (BAL) in infectious processes provide important microbiological and cytological information to manage this type of patient. Most of the clinical and experimental BAL investigations have been done in ventilator-associated pneumonia (VAP) and in immunosuppressed con...

journal_title：Seminars in respiratory and critical care medicine

authors： Ramírez P,Valencia M,Torres A

更新日期：2007-10-01 00:00:00

abstract：:Hepatic sarcoidosis is a relatively common manifestation of extrapulmonary sarcoidosis. It occurs in 20 to 30% of cases and is rarely severe. However, a cluster of patients may develop severe complications such as cirrhosis and portal hypertension. In this review, we describe the current knowledge of clinical, biologi...

journal_title：Seminars in respiratory and critical care medicine

authors： Rossi G,Ziol M,Roulot D,Valeyre D,Mahévas M

更新日期：2020-10-01 00:00:00

abstract：:Pulmonary veno-occlusive disease (PVOD) is a rare disorder and can be misdiagnosed as idiopathic pulmonary arterial hypertension (iPAH). PVOD and iPAH often share a similar clinical presentation, genetic background, and hemodynamic profile. PVOD accounts for 5 to 10% of cases initially considered as iPAH. When compare...

journal_title：Seminars in respiratory and critical care medicine

authors： Montani D,Kemp K,Dorfmuller P,Sitbon O,Simonneau G,Humbert M

更新日期：2009-08-01 00:00:00

abstract：:Pulmonary fibrosis is a devastating disease that occurs in association with environmental exposures, several inherited diseases, collagen vascular disease, as well as in an idiopathic form. Epithelial cell damage, excessive fibroblast proliferation, upregulation of extracellular matrix production, and attenuated matri...

journal_title：Seminars in respiratory and critical care medicine

authors： Wurfel MM,Raghu G

更新日期：2002-04-01 00:00:00

abstract：:Despite advances in positive pressure therapy for obstructive sleep apnea, compliance continues to be a problem for many patients. Sleep apnea surgery is a viable option for patients who are intolerant of positive pressure therapy. This review presents the current state of the art in sleep apnea surgery, including air...

journal_title：Seminars in respiratory and critical care medicine

authors： Li KK

更新日期：2005-02-01 00:00:00

abstract：:Lung cancer in never smokers (LCINS) has lately been recognized as a unique disease based on rapidly gained knowledge from genomic changes to treatment responses. The focus of this article is on current knowledge and challenges with regard to LCINS expanded from recent reviews highlighting five areas: (1) distribution...

journal_title：Seminars in respiratory and critical care medicine

authors： Yang P

更新日期：2011-02-01 00:00:00

abstract：:Increasing donor availability for organ transplantation requires attention to factors that are potentially modifiable. The potential pool of available organs can theoretically be enlarged by considering new sources of organs, including non-beating heart donors, live donor lobar transplants, xenotransplants, and in vit...

journal_title：Seminars in respiratory and critical care medicine

authors： Williams TJ,Snell GI

更新日期：2001-10-01 00:00:00

abstract：:Practicing pulmonologists are often faced with the question of whether a lung disease is related to something in the patient's workplace, home, or recreational environment. Recognizing a lung disease as exposure related creates both opportunities and obligations for clinicians. In addition to managing the patient, the...

journal_title：Seminars in respiratory and critical care medicine

authors： Rose CS,Lynch DA,Cool CD

更新日期：2008-12-01 00:00:00

abstract：:Vasculitides are a heterogeneous group of disorders in which inflammation of blood vessel walls is present at least some time during the course of the disease. Vasculitides can affect any caliber or type of vessel in many anatomic sites; however, the disease can alter more than just vasculature. Given the diversity of...

journal_title：Seminars in respiratory and critical care medicine

authors： Scapa JV,Fishbein GA,Wallace WD,Fishbein MC

更新日期：2018-08-01 00:00:00

abstract：:Asthma is a heterogeneous disorder with a complex etiology. Prevalence rates for asthma have been increasing in many countries over the past few decades. While it is unclear why this increase is occurring, the variation reported in asthma prevalence and severity associated with ethnicity offers some insight into the d...

journal_title：Seminars in respiratory and critical care medicine

authors： Moraes TJ,Sears MR,Subbarao P

更新日期：2018-02-01 00:00:00

abstract：:Acute exacerbations of chronic bronchitis (AECBs) are one of the major causes of morbidity and mortality in the United States, resulting in significant cost to the health care system. Epidemiological information on chronic bronchitis is abundant and has been collected in most industrialized countries. The epidemiology...

journal_title：Seminars in respiratory and critical care medicine

authors： Kim N,Leeper KV Jr

更新日期：2000-01-01 00:00:00

abstract：:Advances have been made in minimally invasive diagnostic procedures in sarcoidosis, including bronchoalveolar lavage (BAL), endobronchial ultrasonography-guided transbronchial needle aspiration (EBUS-TBNA), and positron emission tomography (PET). Several independent groups found almost identical predictive values of t...

journal_title：Seminars in respiratory and critical care medicine

authors： Costabel U,Bonella F,Ohshimo S,Guzman J

更新日期：2010-08-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) in the pediatric population is associated with a variety of underlying diseases and causes, significantly morbidity and mortality. In the majority of patients, PAH in children is idiopathic or associated with congenital heart disease (CHD), with pulmonary hypertension (PH) associa...

journal_title：Seminars in respiratory and critical care medicine

authors： Takatsuki S,Ivy DD

更新日期：2013-10-01 00:00:00

abstract：:Sarcoidosis is by definition a disease of "unknown causes," but recent epidemiologic advances suggest that the long-standing definition of sarcoidosis may soon need to be amended. The recently completed ACCESS (A Case-Control Etiologic Study of Sarcoidosis) study was not able to definitively identify the "cause" of sa...

journal_title：Seminars in respiratory and critical care medicine

authors： Rybicki BA,Iannuzzi MC

更新日期：2007-02-01 00:00:00

abstract：:Acinetobacter baumannii is a highly resilient, gram-negative coccobacillus that thrives within the unique and complex ecological setting of an intensive care unit. This evolving pathogen has now surpassed human capacity to create new antimicrobials, and has led physicians into a concerning era for hospital-acquired in...

journal_title：Seminars in respiratory and critical care medicine

authors： Peleg AY

更新日期：2007-12-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is defined as a mean pulmonary artery pressure greater then 25 mm Hg at rest and greater then 30 mm Hg with exercise in association with normal left heart filling pressures. However, many patients with PAH have much higher pulmonary artery pressures, which, untreated, can rapidly ...

journal_title：Seminars in respiratory and critical care medicine

authors： Bull TM

更新日期：2005-08-01 00:00:00