Anti-inflammatory effects of simvastatin on adipokines in type 2 diabetic patients with carotid atherosclerosis.

abstract：OBJECTIVE:Arterial stiffness has been associated with diabetic retinopathy; however, the information is limited in Asians. We aim to examine the association of central arterial stiffness with the presence and severity of diabetic retinopathy in type 2 diabetes mellitus patients in Singapore. METHODS:Arterial stiffness...

journal_title：Diabetes & vascular disease research

authors： Zhang X,Lim SC,Tavintharan S,Yeoh LY,Sum CF,Ang K,Yeo D,Low S,Kumari N

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:C-type lectin receptors, including Dectin-2, are pattern recognition receptors on monocytes and macrophages that mainly recognize sugars and sugar-like structures present on fungi. Activation of C-type lectin receptors induces downstream CARD9 signalling, leading to the production of cytokines. We hypothesiz...

journal_title：Diabetes & vascular disease research

authors： Thiem K,Hoeke G,Zhou E,Hijmans A,Houben T,Boels MG,Mol IM,Lutgens E,Shiri-Sverdlov R,Bussink J,Kanneganti TD,Boon MR,Stienstra R,Tack CJ,Rensen PC,Netea MG,Berbée JF,van Diepen JA

更新日期：2020-01-01 00:00:00

abstract：:Patients with diabetes mellitus (DM) have accelerated atherosclerosis, which is the main underlying factor contributing to the high risk of atherothrombotic events in these patients. Atherothrombotic complications are the leading cause of morbidity and mortality in patients with DM. Among factors contributing to the p...

journal_title：Diabetes & vascular disease research

authors： Ferreiro JL,Gómez-Hospital JA,Angiolillo DJ

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The development of disturbances in skin microcirculation in type 1 diabetes is not well characterised. We assessed skin microcirculation longitudinally from the onset of diabetes up to 29 years of duration to investigate when such disturbances start. MATERIAL AND METHODS:Seventeen adult patients with type 1...

journal_title：Diabetes & vascular disease research

authors： Santesson P,Lins PE,Kalani M,Adamson U,Lelic I,von Wendt G,Fagrell B,Jörneskog G

更新日期：2017-05-01 00:00:00

abstract：:To assess the prevalence of metabolic syndrome (MS) and estimates of global risk by Framingham Risk Score in young subjects with acute myocardial infarction (MI), we assessed metabolic parameters and global risk assessment in 165 consecutive subjects who presented with myocardial infarction prior to 45 years of age. N...

journal_title：Diabetes & vascular disease research

authors： Zarich S,Luciano C,Hulford J,Abdullah A

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:We have previously reported insignificant changes in HbA1c after exercise in patients with both type 2 diabetes and coronary artery disease. In this study, we investigated the effect of exercise on endothelial function and possible associations between changes in endothelial function and HbA1c. METHODS:Patie...

journal_title：Diabetes & vascular disease research

authors： Byrkjeland R,Njerve IU,Arnesen H,Seljeflot I,Solheim S

更新日期：2017-03-01 00:00:00

abstract：:To assess the non-LDL-C-related dyslipidaemia risk of MI, 823 men aged 23 to 65 with a first MI were compared with 823 MI-free PROCAM controls matched for sex, age, smoking, DM, BP and LDL-C. Overall, the odds of MI in men with HDL-C < 1.15 mmol/L were 2.6 times those of men with HDL-C >or= 1.15 mmol/L, and the odds o...

journal_title：Diabetes & vascular disease research

authors： Assmann G,Cullen P,Schulte H

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:Coronary atherosclerosis in patients with type 2 diabetes mellitus may be promoted by regional fat distribution. We investigated the association between anthropometric measures of obesity, truncal fat mass, epicardial adipose tissue and coronary atherosclerosis in asymptomatic patients and matched controls. ...

journal_title：Diabetes & vascular disease research

authors： Gullaksen S,Funck KL,Laugesen E,Hansen TK,Dey D,Poulsen PL

更新日期：2019-07-01 00:00:00

abstract：:Diabetes contributes directly to the development of cardiovascular aortic valve disease. There is currently no drug therapy available for a dysfunctional valve and this urges the need for additional research to identify distinctive mechanisms of cardiovascular aortic valve disease evolution. The aim of this study was ...

journal_title：Diabetes & vascular disease research

authors： Tucureanu MM,Filippi A,Alexandru N,Ana Constantinescu C,Ciortan L,Macarie R,Vadana M,Voicu G,Frunza S,Nistor D,Simionescu A,Simionescu DT,Georgescu A,Manduteanu I

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Continuous-wave Doppler is frequently used for detecting peripheral arterial disease in patients with diabetes; however, there is limited evidence investigating diagnostic accuracy. This study aimed to determine sensitivity and specificity of continuous-wave Doppler for detecting peripheral arterial disease ...

journal_title：Diabetes & vascular disease research

authors： Tehan PE,Sebastian M,Barwick AL,Chuter VH

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:Assess the effect of risk factors changes on risk for cardiovascular disease and mortality in patients with type 2 diabetes selected from the Swedish National Diabetes Register. METHODS:Observational study of 13,477 females and males aged 30-75 years, with baseline HbA1c 41-67 mmol/mol, systolic blood press...

journal_title：Diabetes & vascular disease research

authors： Eeg-Olofsson K,Zethelius B,Gudbjörnsdottir S,Eliasson B,Svensson AM,Cederholm J

更新日期：2016-07-01 00:00:00

abstract：:The first objective of this study was to determine the baseline prevalence of metabolic syndrome and its individual components using the NCEP-R/ATPIII criteria, IDF criteria for Europe, and IDF criteria for Africa: waist circumference of at least 94 cm for men and women. The second objective was to investigate the inc...

journal_title：Diabetes & vascular disease research

authors： Longo-Mbenza B,On'kin JB,Okwe AN,Kabangu NK,Fuele SM

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Reduced renal function and albuminuria predict cardiovascular (CV) events and mortality in type 2 diabetes (T2D). In addition, we evaluated the role of co-existing congestive heart failure (CHF) and other CV risk factors on CV events in a large observational population-based cohort of T2D patients. RESEARCH ...

journal_title：Diabetes & vascular disease research

authors： Svensson MK,Cederholm J,Eliasson B,Zethelius B,Gudbjörnsdottir S,Swedish National Diabetes Register.

更新日期：2013-11-01 00:00:00

abstract：:The aim of this study was to characterise microvascular blood flow in the skin and to compare it with biomarkers of endothelial dysfunction and tissue inflammation in patients with type 2 diabetes with (n=20) or without (n=20) microvascular complications and 20 control subjects. Microvascular function was measured by ...

journal_title：Diabetes & vascular disease research

authors： Brooks BA,McLennan SV,Twigg SM,Yue DK

更新日期：2008-03-01 00:00:00

abstract：AIM:We examined eligibility and preventable cardiovascular disease events in US adults with diabetes mellitus from the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME). METHODS:We identified adults with diabetes mellitus eligible for EMPA-REG OUTCOME based on tri...

journal_title：Diabetes & vascular disease research

authors： Wong ND,Fan W,Pak J

更新日期：2020-07-01 00:00:00

abstract：:Cardiovascular disease is the most common complication of type 2 diabetes mellitus (type 2 DM), accounting for approximately 80% of deaths. While atherosclerotic vascular disease accounts for much of the cardiovascular morbidity and mortality among diabetic patients, congestive heart failure (CHF) is another key compl...

journal_title：Diabetes & vascular disease research

authors： Patel C,Wyne KL,McGuire DK

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The role of long non-coding RNA in diabetic retinopathy, a serious complication of diabetes mellitus, has attracted increasing attention in recent years. The purpose of this study was to explore whether long non-coding RNA nuclear paraspeckle assembly transcript 1 was involved in the context of diabetic reti...

journal_title：Diabetes & vascular disease research

authors： Li XJ

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To examine the relationship between leisure-time physical activity (LTPA) and the metabolic syndrome in the U.S. adult population. METHODS:The sample (N=5,620) in this cross-sectional study included adults aged 20 years and older. Physical activity was measured in two ways: a six-level measure based upon those...

journal_title：Diabetes & vascular disease research

authors： Churilla JR,Fitzhugh EC

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To investigate the long-term prognostic value of insulin-like growth factor-binding protein 1 in patients with acute myocardial infarction. METHODS:Patients ( n = 180) with admission glucose < 11 mmol/L without previously known diabetes admitted for an acute myocardial infarction in 1998-2000 were followed f...

journal_title：Diabetes & vascular disease research

authors： Ritsinger V,Brismar K,Mellbin L,Näsman P,Rydén L,Söderberg S,Norhammar A

更新日期：2018-09-01 00:00:00

abstract：:We respond to the letter of Nadery and Shahsavari regarding our paper entitled 'Interobserver reliability of the ankle brachial index, toe -brachial index and distal pulse palpation in patients with diabetes. In this letter, we concluded that despite some limitations, the kappa coefficient is an informative measure of...

journal_title：Diabetes & vascular disease research

authors： Álvaro Afonso FJ,García-Morales E,Molines-Barroso RJ,García-Álvarez Y,Sanz-Corbalán I,Lázaro-Martínez JL

更新日期：2018-11-01 00:00:00

abstract：:The objective of this study was to evaluate the safety and tolerability of atorvastatin 10 mg compared with placebo in 2,838 patients with type 2 diabetes and no history of coronary heart disease who were enrolled in the Collaborative Atorvastatin Diabetes Study (CARDS) and followed for 3.9 years. The percentages of p...

journal_title：Diabetes & vascular disease research

authors： Newman CB,Szarek M,Colhoun HM,Betteridge DJ,Durrington PN,Hitman GA,Neil HA,Demicco DA,Auster S,Fuller JH,Cards Investigators.

更新日期：2008-09-01 00:00:00

abstract：:We investigated the usefulness of Holter monitoring to detect cardiac disease and predict future cardiovascular risk in asymptomatic diabetic patients. This is a multi-centre, prospective study in 406 asymptomatic diabetic patients. They were categorized into three groups based on findings of Holter monitoring. A tota...

journal_title：Diabetes & vascular disease research

authors： Nakao YM,Ueshima K,Nohara R,Mizunuma Y,Segawa I,Tanaka-Mizuno S,Yasuno S,Nakao K,Hiramori K,Kihara Y

更新日期：2015-11-01 00:00:00

abstract：:There are few data concerning the relationship between diabetes mellitus, the metabolic syndrome and inflammation following elective percutaneous coronary intervention (PCI). The purpose of this study was to assess basal and peak levels of candidate cytokines in 40 patients undergoing elective PCI. Patients were categ...

journal_title：Diabetes & vascular disease research

authors： Marso SP,Murphy JW,House JA,Safley DM,Harris WS

更新日期：2005-02-01 00:00:00

abstract：:Heart failure is now recognized as a progressive disease in which patients transition through the stages of being at risk of heart failure (stage A), to asymptomatic structural heart disease (stage B), to clinical manifestations of heart failure (stage C) and finally end-stage or refractory heart failure (stage D). Th...

journal_title：Diabetes & vascular disease research

authors： Lam CS

更新日期：2015-07-01 00:00:00

abstract：:Sodium-glucose cotransporter 2 inhibitors are antihyperglycaemic medications with an emerging evidence base for cardiovascular and kidney disease risk reduction. Sodium-glucose cotransporter 2 inhibitors medications lower plasma glucose by inhibiting glucose reabsorption in the proximal tubule of the kidney independen...

journal_title：Diabetes & vascular disease research

authors： de Albuquerque Rocha N,Neeland IJ,McCullough PA,Toto RD,McGuire DK

更新日期：2018-09-01 00:00:00

abstract：:With the growing prevalence of childhood obesity and type 2 diabetes mellitus (T2DM) in youth, the challenge of cardiovascular disease risk management has entered the paediatric realm, affecting specialists, family physicians and allied healthcare professionals alike. Currently, there is little evidence to support opt...

journal_title：Diabetes & vascular disease research

authors： McGavock J,Sellers E,Dean H

更新日期：2007-12-01 00:00:00

abstract：:Diabetes mellitus and angina pectoris are important conditions in older persons. The utility of pre-diabetes mellitus, diabetes mellitus and other risk factors as predictors of incident angina pectoris among older adults has not been characterized. We examined incident angina pectoris rates by sex and diabetes mellitu...

journal_title：Diabetes & vascular disease research

authors： Mathenge N,Fan W,Wong ND,Hirsch C,Delaney CJ,Amsterdam EA,Koch B,Calara R,Gardin JM

更新日期：2020-01-01 00:00:00

abstract：:Guidelines recommend aggressive goals for lipid and blood pressure reduction for high risk patients with diabetes mellitus and atherosclerotic coronary disease. However, it remains unclear how many patients achieve treatment goals versus the number of people merely placed on treatment. We conducted an observational st...

journal_title：Diabetes & vascular disease research

authors： DeGuzman PB,Akosah KO,Simpson AG,Barbieri KE,Megginson GC,Goldberg RI,Beller GA

更新日期：2012-04-01 00:00:00

abstract：:Telmisartan partially activates the peroxisome proliferator-activated receptor γ (PPARγ), which may ameliorate the accumulation of visceral adipose tissues and sensitise insulin action. Nineteen patients with essential hypertension and metabolic syndrome were randomly assigned to receive 40 mg of telmisartan (TELMI gr...

journal_title：Diabetes & vascular disease research

authors： Murakami K,Wada J,Ogawa D,Horiguchi CS,Miyoshi T,Sasaki M,Uchida HA,Nakamura Y,Makino H

更新日期：2013-01-01 00:00:00

abstract：:A cross-sectional analysis of ethnic differences in dietary intake, insulin sensitivity and beta-cell function, using the intravenous glucose tolerance test (IVGTT), was conducted on 497 healthy adult participants of the 'Reading, Imperial, Surrey, Cambridge, and Kings' (RISCK) study. Insulin sensitivity (Si) was sign...

journal_title：Diabetes & vascular disease research

authors： Goff LM,Griffin BA,Lovegrove JA,Sanders TA,Jebb SA,Bluck LJ,Frost GS,RISCK Study Group.

更新日期：2013-07-01 00:00:00