Abstract:
:Evidence suggests that individuals who are more obese may be more responsive to stress. Stress activates the sympathetic nervous system (SNS) and the adipose-tissue cytokine leptin stimulates SNS activity in animals. We examined the relationship between adiposity, leptin and physiological responses to acute laboratory stress in 67 women. We predicted that individuals with greater adiposity and/or higher plasma leptin would be more stress-responsive. Adiposity was unrelated to cardiovascular or neuroendocrine stress reactivity. However, women with larger waists had greater stress-induced increases in plasma leptin and interleukin-1 receptor antagonist (IL-1Ra). Similarly, women with higher basal leptin displayed greater stress-induced increases in heart rate and plasma interleukin-6, and larger decreases in heart rate variability and cardiac pre-ejection period. Heightened cardiovascular and inflammatory stress responses are predictive of future cardiovascular risk. Our findings suggest that the cytokines leptin and IL-1Ra may play a role in the association between obesity, stress and cardiovascular health.
journal_name
Biol Psycholjournal_title
Biological psychologyauthors
Brydon Ldoi
10.1016/j.biopsycho.2010.02.010subject
Has Abstractpub_date
2011-02-01 00:00:00pages
114-20issue
2eissn
0301-0511issn
1873-6246pii
S0301-0511(10)00066-9journal_volume
86pub_type
杂志文章abstract::Obsessional-compulsive disorder has been conceptualised in terms of overattention to irrelevant details. The aim of the present study was to investigate whether this feature would be reflected in the 'early' CNV component. Sixteen obsessional patients and matched controls were tested in a motor-set CNV paradigm with a...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(84)90057-7
更新日期:1984-06-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2008.07.001
更新日期:2008-10-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2008.02.006
更新日期:2009-01-01 00:00:00
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journal_title:Biological psychology
pub_type: 历史文章,杂志文章,评审
doi:10.1016/0301-0511(88)90013-0
更新日期:1988-06-01 00:00:00
abstract::Social Anxiety Disorder (SAD) symptoms demonstrate a marked persistence over time, but little is known empirically about short-term processes that may account for this long-term persistence. In this study, we examined how self-reported and physiological stress reactivity were associated with persistence of SAD symptom...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2017.03.003
更新日期:2017-04-01 00:00:00
abstract::A theoretical framework has been put forward to understand attention deficits in schizophrenia (Luck SJ & Gold JM. Biological Psychiatry. 2008; 64:34-39). We adopted this framework to evaluate any deficits in attentional processes in schizotypy. Sixteen low schizotypal (LoS) and 16 high schizotypal (HiS) individuals p...
journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2015.06.007
更新日期:2015-07-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(89)90034-3
更新日期:1989-10-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.09.006
更新日期:2013-12-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章,随机对照试验
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更新日期:2019-03-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.10.005
更新日期:2013-12-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2019.107729
更新日期:2019-11-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2006.06.005
更新日期:2007-01-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.09.009
更新日期:2014-01-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(92)90027-r
更新日期:1992-07-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(75)90033-2
更新日期:1975-11-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2011.07.007
更新日期:2011-12-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(80)90002-2
更新日期:1980-02-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(88)90034-8
更新日期:1988-12-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2019.02.010
更新日期:2019-04-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2014.06.003
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2017.07.006
更新日期:2017-09-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.01.004
更新日期:2013-04-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(90)90016-p
更新日期:1990-10-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2013.09.005
更新日期:2013-12-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2011.08.012
更新日期:2011-12-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(85)90038-9
更新日期:1985-02-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2012.07.002
更新日期:2012-10-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/0301-0511(84)90036-x
更新日期:1984-12-01 00:00:00
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journal_title:Biological psychology
pub_type: 杂志文章
doi:10.1016/j.biopsycho.2015.04.010
更新日期:2015-07-01 00:00:00