Abstract:
:Hepatitis B virus (HBV) infection remains a major health concern with more than 350 million carriers in the world. It is associated with acute and chronic liver diseases including hepatocellular carcinoma (HCC). The early detection of severe liver diseases related to HBV is crucial for the effective treatment. This work aims to investigate the secreted proteins in our recently established cell-based HBV replication system, using isobaric tags for relative and absolute quantitation (iTRAQ)-coupled 2D LC-MS/MS proteomics approach. Such proteins are reflective of early events of HBV infection and thus may have potential as prognostic biomarkers for development of liver diseases.
journal_name
Curr Microbioljournal_title
Current microbiologyauthors
Feng H,Wang M,Chen WNdoi
10.1007/s00284-010-9608-3subject
Has Abstractpub_date
2010-10-01 00:00:00pages
280-4issue
4eissn
0343-8651issn
1432-0991journal_volume
61pub_type
杂志文章abstract::Lake Elmenteita is one of the alkaline saline lakes within the Kenyan Rift valley. The lake is situated on the floor of the Kenyan Rift Valley at 1,776 m above sea level and has no direct outlet. The microbial diversity of the lake was investigated using a culture-independent approach. Five different sampling points w...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-010-9692-4
更新日期:2011-01-01 00:00:00
abstract::Thirteen clinical isolates of Pasteurella multocida from a variety of different animals and humans were examined for their ability to produce lipase. Lipase substrates used included Tween 20, Tween 40, Tween 80, and Tween 85. Lipase activity was detected in the filtrates of organisms grown to the exponential phase in ...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s002849910061
更新日期:2000-05-01 00:00:00
abstract::Iron-oxidizing Acidithiobacillus spp. are applied worldwide in biomining industry to extract metals from sulfide minerals. They derive energy for survival through Fe2+ oxidation and generate Fe3+ for the dissolution of sulfide minerals. However, molecular mechanisms of their iron oxidation still remain elusive. A nove...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-018-1453-9
更新日期:2018-07-01 00:00:00
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-003-4186-2
更新日期:2004-04-01 00:00:00
abstract::A strain-designated YsT was isolated as a filterable bacterial strain from Lake Sanaru, a brackish water lake in Hamamatsu Japan. YsT is aerobic, Gram-negative, and slender rod shaped. YsT grew optimally at 30 °C, pH 7.0-8.0 and without the addition of NaCl. MK-7 was the sole isoprenoid quinone. The main cellular pola...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-019-01823-4
更新日期:2020-02-01 00:00:00
abstract::Three aerobic bacterial consortia, AC, BC, and DC, developed from pesticide-contaminated soils of Punjab were able to degrade chlorpyrifos after 21 days of incubation in basal medium by 54, 46, and 61% and chlorpyrifos (50 mg/L) in soil after 30 days by 50, 56, and 64%. Pseudomonas aeruginosa, Bacillus cereus, Klebsie...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-008-9262-1
更新日期:2009-01-01 00:00:00
abstract::We report the in vitro phytopathogen suppression activity of siderophoregenic preparations of Alcaligenes feacalis vis-à-vis the oraganochlorine fungicide, bavistin. Siderophore-rich culture broth, siderophore-rich supernatant, and purified siderophore preparation exerted antifungal activity against Aspergillus niger ...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-008-9264-z
更新日期:2009-01-01 00:00:00
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-014-0657-x
更新日期:2014-12-01 00:00:00
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-017-1217-y
更新日期:2017-04-01 00:00:00
abstract::The alphaproteobacterial strain JLT2003(T) was isolated from surface seawater off the coast of Guishan island, Taiwan. The strain was Gram negative, ovoid or coccoid, non-motile and formed pink colonies on marine agar 2216 (MA; DIFCO) medium. The dominant fatty acids were C(18:1)ω7c, cyclo C(19:0)ω8c, and C(16:0). The...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-012-0081-z
更新日期:2012-04-01 00:00:00
abstract::The glucose 1-phosphate uridylyltransferase (GalU) is absolutely required for the biosynthesis of capsular polysaccharide, the sine qua non virulence factor of Streptococcus pneumoniae. The pneumococcal GalU protein was overexpressed in Escherichia coli, and purified. GalU showed a pI of 4.23, and catalyzed the revers...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-005-4466-0
更新日期:2005-10-01 00:00:00
abstract::A plant growth-promoting Paenibacillus lentimorbus NRRL B-30488 (B-30488) was isolated from cows' milk. Bacterial colonization and growth responses of different plant species after inoculation with B-30488 were evaluated in a controlled environment and in microplot assays. Survival and colonization of B-30488 in the p...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-006-0261-9
更新日期:2006-12-01 00:00:00
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s002849910027
更新日期:2000-02-01 00:00:00
abstract::Panax notoginseng has long been used as a Chinese herb with high medicinal value. The endophytic bacteria in this medicinal plant have multiple biological functions. High-throughput sequencing is a rapidly evolving technique that helps profile the endophytic bacterial community structure of medicinal plants. However, ...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-020-02068-2
更新日期:2020-10-01 00:00:00
abstract::In Neurospora crassa, multinucleate macroconidia are used for genetic transformation. The barrier for such a transformation can be either at the cell membrane level or at the nuclear membrane level. For assessment of these possibilities, a forced heterokaryon (containing two genetically marked nuclei and auxotrophic f...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-001-0004-x
更新日期:2002-05-01 00:00:00
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-015-0868-9
更新日期:2015-10-01 00:00:00
abstract::Strain NHI-24(T) was isolated from forest soil by a polycarbonate membrane transwell plate. It is a Gram-negative, rod-shaped, non-motile, non-spore-forming bacterium. Phylogenetic analysis based on 16S rRNA gene sequence data indicated that strain NHI-24(T) is closely related to members of the genus Niabella: N. dril...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-014-0565-0
更新日期:2014-08-01 00:00:00
abstract::Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) displays important functional diversity in mammalian and plants. So far, however, studies on GAPDH have not included the halotolerant, unicellular green alga Dunaliella salina. In the present study, a GAPDH cDNA was cloned and sequenced from D. salina. It was 1394 bp lo...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-008-9333-3
更新日期:2009-05-01 00:00:00
abstract::Favre and coworkers (Favre et al., Biochimie 73:235-244, 1991) previously reported that the Bordetella pertussis recA gene present at high copy number could promote a low frequency of recombination, but not bacteriophage induction in Escherichia coli RecA- mutants. Reexamination of these phenotypes demonstrated that, ...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s002849900029
更新日期:1996-03-01 00:00:00
abstract::Flammulina velutipes is a potentially excellent fungus to study basic mechanisms of basidiomycete mycelium biology. To provide a better understanding of the mechanism of hyphae growth and fruit-body formation, the biological functions of the differentially abundant proteins between the fruiting dikaryon and the non-fr...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-016-1164-z
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-003-4143-0
更新日期:2004-02-01 00:00:00
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-013-0383-9
更新日期:2013-10-01 00:00:00
abstract::Whole-crystal preparations from strains HD-1 and HD-133, activated Cry1Ab and Cry1C toxins as well as Cry1Aa, Cry1Ac, Cry1D, and Cry2Aa protoxins were tested for toxicity to 2nd-instar larvae of the diamondback moth, Plutella xylostella. Mortality data recorded after 2 and 5 days provided different results that were r...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s002849900438
更新日期:1999-09-01 00:00:00
abstract::Although neutral mine drainage is the less frequent subject of the interest than acid mine drainage, it can have adverse environmental effects caused mainly by precipitation of dissolved Fe. The aim of the study was to characterize the composition of bacterial population in environment with high concentration of iron ...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-018-1472-6
更新日期:2018-08-01 00:00:00
abstract::Ansamitocins are extraordinarily potent antitumor agents. Ansamitocin P-3 (AP-3), which is produced by Actinosynnema pretiosum, has been developed as a cytotoxic drug for breast cancer. Despite its importance, AP-3 is of limited applicability because of the low production yield. A. pretiosum strain X47 was developed f...
journal_title:Current microbiology
pub_type: 信件
doi:10.1007/s00284-018-1521-1
更新日期:2019-08-01 00:00:00
abstract::Probiotics are well known for their wide range of beneficial activities. However, recent use of probiotic Bifidobacterium, Enterococcus, and Lactobacillus spp. has been plagued by certain disadvantages such as complex growth requirements, high maintenance cost, susceptibility to the gastrointestinal environment, patho...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-019-01647-2
更新日期:2019-04-01 00:00:00
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journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-016-1176-8
更新日期:2017-02-01 00:00:00
abstract::Potassium ion pool was studied in glycolyzing Enterococcus hirae, grown at high or low alkaline pH (pH 9.5 and 8.0, respectively). Energy-dependent increase of K+ pool was lower for the wild-type cells, grown at pH 9.5, than that for the cells grown at pH 8.0. It was inhibited by N,N'-dicyclohexylcarbodiimide (DCCD). ...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s002849900289
更新日期:1998-02-01 00:00:00
abstract::The regulation of the recA gene expression in the obligately anaerobic rumen bacterium Prevotella ruminicola was investigated by monitoring the recA-specific transcript level. P. ruminicola recA forms a monocistronic unit, but no SOS-box sequences resembling those of Escherichia coli or Bacillus subtilis can be identi...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s002849900306
更新日期:1998-05-01 00:00:00
abstract::We constructed recombinant phage particles displaying the Bacillus thuringiensis Cry1Ba4 active toxin using the pfUSE5 and pComb3X phagemid vectors. The recombinant phage particles were screened and evaluated for displayed biologically active Cry1Ba4 toxin against the target insect larvae. Concurrent expression of Cry...
journal_title:Current microbiology
pub_type: 杂志文章
doi:10.1007/s00284-006-0164-9
更新日期:2006-11-01 00:00:00