Abstract：
:Scales of snakes contain hard proteins (beta-keratins), now referred to as keratin-associated beta-proteins. In the present study we report the isolation, sequencing, and expression of a new group of these proteins from snake epidermis, designated cysteine-glycine-proline-rich proteins. One deduced protein from expressed mRNAs contains 128 amino acids (12.5 kDa) with a theoretical pI at 7.95, containing 10.2% cysteine and 15.6% glycine. The sequences of two more snake cysteine-proline-rich proteins have been identified from genomic DNA. In situ hybridization shows that the messengers for these proteins are present in the suprabasal and early differentiating beta-cells of the renewing scale epidermis. The present study shows that snake scales, as previously seen in scales of lizards, contain cysteine-rich beta-proteins in addition to glycine-rich beta-proteins. These keratin-associated beta-proteins mix with intermediate filament keratins (alpha-keratins) to produce the resistant corneous layer of snake scales. The specific proportion of these two subfamilies of proteins in different scales can determine various degrees of hardness in scales.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Dalla Valle L,Nardi A,Alibardi Ldoi
10.1111/j.1469-7580.2009.01192.xsubject
Has Abstractpub_date
2010-03-01 00:00:00pages
356-67issue
3eissn
0021-8782issn
1469-7580pii
JOA1192journal_volume
216pub_type
杂志文章abstract：:Femoral neck fractures are a major cause of morbidity and mortality in elderly humans. In addition to the age-related loss of cancellous bone, changes to the microstructure and morphology of the metaphyseal cortex may be a contributing factor in osteoporotic hip fractures. Recent investigations have identified a hyper...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2001.19820153.x
更新日期：2001-02-01 00:00:00
abstract：:Scanning microinterferometric measurements were made of matrix dry mass in the intermediate layer of normal rabbit patellar articular cartilage and in the area surrounding standard, experimental, full-thickness lesions of 1-5 mm diameter. The lesions were created in 1 kg animals and were allowed to heal for up to 3 we...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:The proposal that the cytoplasmic granules of glomerular peripolar cells (PPCs) of the adult sheep and lamb contain a kallikrein-like substance has been re-examined. After extensive characterisation and purification of anti-kallikrein antibodies, it was concluded that PPCs do not contain immunohistochemically detectab...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:This study uses a bovine patella model to compare the relative merits of on-bone compliance and thickness measurements, free-swelling behaviour, and structural imaging with differential interference contrast (DIC) light microscopy to assess the biomechanical normality of the cartilage matrix. The results demonstrate t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00184.x
更新日期：2003-06-01 00:00:00
abstract：:A silver impregnation technique (Linder, 1978) has been applied to whole mounts of the rat iris. The results suggest that only sensory fibres, both myelinated and non-myelinated, are stained. They disappear only after a trigeminal lesion and their distribution is different from that of catecholaminergic intrinsic fibr...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：:The paraspinal compartment acts as a bone-muscle composite beam of the spine. The elastic properties of the paraspinal muscles play a critical role in spine stabilization. These properties depend on the subjects' posture, and they may be drastically altered by low back pain. Supersonic shear wave elastography can be u...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12978
更新日期：2019-06-01 00:00:00
abstract：:The cytoarchitecture of the intra-ocular optic nerve was investigated by light and electron microscopy. Glial cells in the intra-ocular portion are disposed among the axons, either scattered or forming columns, and bordering the nervous parenchyma. Astroglia forms the limiting glia that separates the optic nerve from ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:Human mesenchymal stem cells (hMSC) are a heterogeneous cell population, which is reflected in varying morphological and biological properties. Three subpopulations with intrinsic characteristics can be distinguished: small rapidly self-renewing cells, spindle-shaped cells and large, flattened cells. Unfortunately, it...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01065.x
更新日期：2009-05-01 00:00:00
abstract：:Providing formative assessment opportunities has been recognised as a significant benefit to student learning. The outcome of any formative assessment should be one that ultimately helps improve student learning through familiarising students with the levels of learning required, informing them about gaps in their lea...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/joa.12117
更新日期：2014-03-01 00:00:00
abstract：:The geometry-dependent functioning of the meniscus indicates that detailed knowledge on 3D meniscus geometry and its inter-subject variation is essential to design well functioning anatomically shaped meniscus replacements. Therefore, the aim of this study was to quantify 3D meniscus geometry and to determine whether ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12223
更新日期：2014-10-01 00:00:00
abstract：:This study set out to determine the pattern of development and distribution of the interstitial cells of Cajal (ICC) in the intestinal tract of the equine fetus and neonate. Intestinal tissue samples from 12 naturally aborted equine fetuses and three euthanized neonates were collected and fixed in formalin prior to ap...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.0021-8782.2004.00315.x
更新日期：2004-07-01 00:00:00
abstract：:Despite the long-held assumption that olfaction plays a relatively minor role in the behavioral ecology of birds, crown-group avians exhibit marked phylogenetic variation in the size and form of the olfactory apparatus. As part of a larger effort to better understand the role of olfaction and olfactory tissues in the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13197
更新日期：2020-08-01 00:00:00
abstract：:Integrating microdensitometry was used to study changes in the intracellular activity of 4 enzymes during macrophage development. Suspension cultures of blood monocytes from 19 healthy human subjects were examined at 0, 2, 4 and 6 d. Mononuclear phagocytes were harvested by glass adherence and standard methods were us...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
abstract：:The lungs of 3 small passerine species, having similar body mass but different diurnal activity patterns, were analysed morphometrically to assess the relationship between diurnal activity and pulmonary volumetry at the light and electron microscope levels. The percentage volumes of the major lung and exchange tissue ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1998.19340573.x
更新日期：1998-11-01 00:00:00
abstract：:The surface area and volume of 79 human fetuses (body weight 8-4080 g) were estimated by use of a geometric method. It was found that body surface area increased by a factor of about 70, and body volume by a factor of about 400, during the fetal period. Surface area (S, in cm2) was related to body weight (W, in g) and...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-09-01 00:00:00
abstract：:Observations have been made on the rabbit sciatic nerve distal to a transection, with survival periods of up to 26 mo and prevention of reinnervation. It was confirmed that the nerve becomes compartmented by fibroblast processes and that a zone of fine collagen fibrils develops around the Schwann cell columns that con...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1998.19240529.x
更新日期：1998-05-01 00:00:00
abstract：:Mammalian neonates are born at a wide range of maturity levels. Altricial newborns are born with limited sensory agency and require extensive parental care. In contrast, precocial neonates are relatively mature physically and often capable of independent function shortly after birth. In extant mammals, placental newbo...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13127
更新日期：2020-04-01 00:00:00
abstract：:The occipital squama of the Japanese musk shrew, Suncus murinus, consists only of membrane bone which arises from the periosteal bony band of the supraoccipital cartilage. No cartilaginous tectum posterius, generally forming the dorsal border to the foramen magnum, was found in the developing chondrocranium. Also addi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:The T-tubule system in cardiac muscle cells has been investigated with the electron microscope in 10 adult rats after infiltration with horseradish peroxidase. All cardiac muscle cells possess a T-system, but its complexity varies according to the region of the heart. It is most extensive in the general ventricular my...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1978-09-01 00:00:00
abstract：:This study describes at the ultrastructural level the neuronal changes in the intracardiac ganglia of the monkey (Macaca fascicularis) following unilateral vagotomy. One day after unilateral vagotomy, some intracardiac neurons showed an overall increase in electron density, with the dendrites darkening first. At three...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Whether the 1st segment of the human autopod 1st ray is a 'true' metapodial with loss of the proximal or mid phalanx or the original basal phalanx with loss of the metacarpal has been a long-lasting discussion. The actual knowledge of the developmental pattern of upper autopod segments at a fetal age of 20-22 weeks, c...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12883
更新日期：2018-12-01 00:00:00
abstract：:The feet of apes have a different morphology from those of humans. Until now, it has merely been assumed that the morphology seen in humans must be adaptive for habitual bipedal walking, as the habitual use of bipedal walking is generally regarded as one of the most clear-cut differences between humans and apes. This ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12201
更新日期：2014-08-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-12-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01386.x
更新日期：2011-08-01 00:00:00
abstract：:We examined the effects of exercise on diaphragm degeneration and cardiomyopathy in dystrophin-deficient mdx mice. Mdx mice (11 months of age) were exercised (swimming) for 2 months to worsen diaphragm degeneration. Control mdx mice were kept sedentary. Morphological evaluation demonstrated increased fibrosis in the d...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12443
更新日期：2016-05-01 00:00:00
abstract：:In a prospective cross-sectional ultrasound study the size of the fetal lumbar spinal canal was evaluated to determine reference values for the lumbar part of the vertebral canal. One hundred and sixty-seven pregnant women undergoing routine obstetric ultrasound were studied between 16 and 41 weeks of gestation. Exclu...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2002.00048.x
更新日期：2002-05-01 00:00:00
abstract：:Bone growth at the cranial sutures relies on proliferation of osteogenic progenitor cells and/or differentiation of osteoblasts. The current study was undertaken to assess these events in relation to suture growth and fusion. A total of 21 pigs, divided into three age groups (0.5-1.5 months, 3-4 months and 5-7 months)...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2007.00761.x
更新日期：2007-09-01 00:00:00
abstract：:The fine structure of the elastic cartilage of the pinna has been examined in young rabbits aged from 1 day to 1108 days. Changes associated with growth and development are related not only to age but also to the actual situation in the pinna. In the midline, progressive changes are seen from the tip to the base. The ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:Lateral nasal glands of 12-15 weeks old pups are immature. Gland acini of pups and mature dogs contain numerous electron-lucent vacuoles with basophilic, electron-dense cores. The vacuoles contain both acid and neutral glycoproteins, sialated glycoproteins being the dominant acidic moiety. Lateral and basal cytoplasmi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:In the enameloid matrix a large number of tubular vesicles appeared around the odontoblast processes at the stage of enameloid matrix formation. The tubular vesicles were limited by unit membrane and the membrane often seemed to connect with that of the odontoblast processes. The tubular vesicles probably originated f...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
