Sentinel lymph node mapping by a near-infrared fluorescent heptamethine dye.

abstract：:Polysaccharides are increasingly being used as biomaterials for tissue engineering and regenerative medicine. Quantitative analysis of gene expression from cells in three-dimensional (3D) scaffolds requires extraction of messenger RNA, which is complicated in polysaccharide materials by ionic complexing between nuclei...

journal_title：Biomaterials

authors： Wang L,Stegemann JP

更新日期：2010-03-01 00:00:00

abstract：:Ultrasoft biomaterials-polymers, gels, and human soft tissues with an elastic modulus less than ∼100 kPa-are increasingly used in medical devices. While bacterial interactions (adhesion and biofilm formation) have been extensively studied on stiffer materials, little is known about how bacteria colonize ultrasoft mate...

journal_title：Biomaterials

authors： Wang Y,Guan A,Isayeva I,Vorvolakos K,Das S,Li Z,Phillips KS

更新日期：2016-07-01 00:00:00

abstract：:Nowadays, two-dimensional (2D) nanomaterials with many fascinating physicochemical properties have drawn extensive attention as drug delivery platforms for cancer theranostics. Nevertheless, current existing 2D nanomaterial-based drug delivery systems normally undergo the bottlenecks of hash preparation process, low d...

journal_title：Biomaterials

authors： Liu F,Lin L,Zhang Y,Sheng S,Wang Y,Xu C,Tian H,Chen X

更新日期：2019-12-01 00:00:00

abstract：:A UV-hardening lacquer material based on polyurethane, used in Philips compact disc lens systems, was tested as suitable material for low-cost intraocular lenses (IOLs). A slightly changed composition (code number I-0.5A) came out as the best and was subsequently tested, with reference to poly(methyl methacrylate) (PM...

journal_title：Biomaterials

authors： Jongebloed WL,van der Veen G,Kalicharan D,van Andel MV,Bartman G,Worst JG

更新日期：1994-08-01 00:00:00

abstract：:Microcomputed tomography (micro-CT) is increasingly being used to analyze the three-dimensional structure and architecture of microvascular networks. Therefore we have evaluated a micro-CT analysis of VEGF-induced vessel ingrowth into a porous polyurethane scaffold through comparison with analyses by CD31 immunohistoc...

journal_title：Biomaterials

authors： Schmidt C,Bezuidenhout D,Beck M,Van der Merwe E,Zilla P,Davies N

更新日期：2009-10-01 00:00:00

abstract：:The non-specific interaction between nanoparticles (NPs) and plasma proteins occurs immediately after NPs enter the blood, resulting in the formation of the protein corona that thereafter replaces the original NPs and becomes what the organs and cells really see. Consequently, the in vivo fate of NPs and the biologica...

journal_title：Biomaterials

authors： Peng Q,Zhang S,Yang Q,Zhang T,Wei XQ,Jiang L,Zhang CL,Chen QM,Zhang ZR,Lin YF

更新日期：2013-11-01 00:00:00

abstract：:In regenerative medicine, accumulating evidence demonstrates that the property of substrates monitors neural stem cells behavior. However, how stem cells sense and interpret biochemical and topographical cues remains elusive. This study aimed to explore the mechanism how nanofibrous scaffold modulated stem cells behav...

journal_title：Biomaterials

authors： Wang Y,Yao M,Zhou J,Zheng W,Zhou C,Dong D,Liu Y,Teng Z,Jiang Y,Wei G,Cui X

更新日期：2011-10-01 00:00:00

abstract：:Microcontact printed polymeric substrates were evaluated for their ability to control Schwann cell attachment and direct proliferation, as Schwann cell guidance is a crucial factor in directing peripheral nerve regeneration. Elastomeric stamps of poly(dimethylsiloxane) were "inked" with laminin, a permissive protein f...

journal_title：Biomaterials

authors： Schmalenberg KE,Uhrich KE

更新日期：2005-04-01 00:00:00

abstract：:The non-collagenous proteins of mature cortical rabbit bone and 3 wk old bone specimens formed in titanium implant bone harvest chambers, were separated by means of fine pressure liquid chromatography. It was found that a sufficient amount of bone could be obtained from five bone harvest chambers in five rabbits durin...

journal_title：Biomaterials

authors： Lundgren T,Sennerby L

更新日期：1990-04-01 00:00:00

abstract：:Synthetic polymer scaffold seeded with autologous cells have a clinical translational potential. A rational design oriented to clinical applications must ensure an efficient mass transfer of nutrients as a function of specific metabolic rates, especially for precariously vascularized tissues grown in vitro or integrat...

journal_title：Biomaterials

authors： Curcio E,Piscioneri A,Morelli S,Salerno S,Macchiarini P,De Bartolo L

更新日期：2014-08-01 00:00:00

abstract：:The neutrophil polarization assay, a technique used to measure chemotaxis, was adapted to examine complement activation. Complement activation in serum which had been incubated with metallic and polymeric biomaterials was examined using the neutrophil polarization assay and immunoelectrophoresis assay. In agreement wi...

journal_title：Biomaterials

authors： Remes A,Williams DF

更新日期：1991-08-01 00:00:00

abstract：:Targeted drug delivery with precisely controlled drug release and activation is highly demanding and challenging for tumor precision therapy. Herein, a biomimetic cascade nanoreactor (designated as Mem@GOx@ZIF-8@BDOX) is constructed for tumor targeted starvation therapy-amplified chemotherapy by assembling tumor cell ...

journal_title：Biomaterials

authors： Cheng H,Jiang XY,Zheng RR,Zuo SJ,Zhao LP,Fan GL,Xie BR,Yu XY,Li SY,Zhang XZ

更新日期：2019-03-01 00:00:00

abstract：:Supramolecular assemblies have attracted a great attention, due to their intriguing topologies and their application in various fields such as nanodevices, sensors, molecular switches, and drug delivery systems. In this study, we prepared the monosubstituted insulin with poly(ethylene glycol) (PEG, MW about 2200) and ...

journal_title：Biomaterials

authors： Higashi T,Hirayama F,Misumi S,Arima H,Uekama K

更新日期：2008-10-01 00:00:00

abstract：:Human adipose tissue extracellular matrix, derived through decellularization processing, has been shown to provide a biomimetic microenvironment for adipose tissue regeneration. This study reports the use of human adipose tissue-derived extracellular matrix (hDAM) scaffolds as a three-dimensional cell culturing system...

journal_title：Biomaterials

authors： Dunne LW,Huang Z,Meng W,Fan X,Zhang N,Zhang Q,An Z

更新日期：2014-06-01 00:00:00

abstract：:Although silicones possess many useful properties as biomaterials, their hydrophobicity can be problematic. To a degree, this issue can be addressed by surface modification with hydrophilic polymers such as poly(ethylene glycol), but the resulting structures are usually not conducive to cell growth. In the present wor...

journal_title：Biomaterials

authors： Alauzun JG,Young S,D'Souza R,Liu L,Brook MA,Sheardown HD

更新日期：2010-05-01 00:00:00

abstract：:Endotoxemia is a severe pathophysiology induced by bacterial endotoxin (also known as lipopolysaccharide, LPS), causing high mortality in clinic due to the life-threatening syndromes, such as sepsis, shock, and multiple organ dysfunction. Removing or neutralizing endotoxin from the circulatory system has been proven t...

journal_title：Biomaterials

authors： Shen S,Han F,Yuan A,Wu L,Cao J,Qian J,Qi X,Yan Y,Ge Y

更新日期：2019-01-01 00:00:00

abstract：:Suture materials may interact with immune competent cells and thereby affect localized immunity. Macrophages are central to the inflammatory response and coordinate wound healing. They are also involved in the clearance of foreign material, bacteria and malignant cells. We studied the influence of soluble factors asso...

journal_title：Biomaterials

authors： Uff CR,Scott AD,Pockley AG,Phillips RK

更新日期：1995-03-01 00:00:00

abstract：:Water uptake characteristics of BisGMA-based composites incorporating untreated and surface-treated hydroxyapatite (HA) with a silane coupling agent have been investigated. The water absorption and desorption behaviour of these composites obeyed the classical diffusion theory. The diffusion coefficients of the composi...

journal_title：Biomaterials

authors： Santos C,Clarke RL,Braden M,Guitian F,Davy KW

更新日期：2002-04-01 00:00:00

abstract：:Successful cell-based tissue engineering requires a rapid and thorough vascularization in order to ensure long-term implant survival and tissue integration. The vascularization of a scaffold is a complex process, and is modulated by the presence of transplanted cells, exogenous and endogenous signaling proteins, and t...

journal_title：Biomaterials

authors： Ghanaati S,Unger RE,Webber MJ,Barbeck M,Orth C,Kirkpatrick JA,Booms P,Motta A,Migliaresi C,Sader RA,Kirkpatrick CJ

更新日期：2011-11-01 00:00:00

abstract：:Two types of isoelastic endosseous dental implants were produced and their functionality was tested. One type consisted of a porous sintered TiTa30 alloy, the other had a special surface structure consisting of titanium wire loops. Their mechanical properties were optimized by the production parameter (sintering and d...

journal_title：Biomaterials

authors： Breme J,Biehl V,Schulte W,d'Hoedt B,Donath K

更新日期：1993-10-01 00:00:00

abstract：:Bioactive coatings for neural electrodes that are tailored for cell interactions have the potential to produce superior implants with improved charge transfer capabilities. In this study synthetically produced anionically modified laminin peptides DEDEDYFQRYLI and DCDPGYIGSR were used to dope poly(3,4-ethylenedioxythi...

journal_title：Biomaterials

authors： Green RA,Lovell NH,Poole-Warren LA

更新日期：2009-08-01 00:00:00

abstract：:Adhesion of tissue cells is a prerequisite for their growth and differentiation but prevents also apoptosis. Here the layer-by-layer technique (LbL) was used to design multilayer structures of poly(ethylene imine) (PEI) and heparin (HEP) on glass as model biomaterial to control the adhesion of primary human dermal fib...

journal_title：Biomaterials

authors： Niepel MS,Peschel D,Sisquella X,Planell JA,Groth T

更新日期：2009-10-01 00:00:00

abstract：:Programmable hydrogels are defined as hydrogels that are able to change their properties and functions periodically, reversibly and/or sequentially on demand. They are different from those responsive hydrogels whose changes are passive or cannot be stopped or reversed once started and vice versa. The purpose of this r...

journal_title：Biomaterials

authors： Wang Y

更新日期：2018-09-01 00:00:00

abstract：:We have designed a dual-aptamer complex specific to both prostate-specific membrane antigens (PSMA) (+) and (-) prostate cancer cells. In the complex, an A10 RNA aptamer targeting PSMA (+) cells and a DUP-1 peptide aptamer specific to PSMA (-) cells were conjugated through streptavidin. Doxorubicin-loaded onto the ste...

journal_title：Biomaterials

authors： Min K,Jo H,Song K,Cho M,Chun YS,Jon S,Kim WJ,Ban C

更新日期：2011-03-01 00:00:00

abstract：:Measurements were made of the extremes in temperature which occur at different sites in the oral cavity during fluid intake. The results indicate that temperatures noted at the tooth surface, within the mouth, during fluid intake were less than the temperatures of the fluid imbibed. Variations in temperature were note...

journal_title：Biomaterials

authors： Longman CM,Pearson GJ

更新日期：1987-09-01 00:00:00

abstract：:The infection of an implanted prosthetic material can have serious consequences on the tissue integration of the implant and the scarring process in the host, and may even necessitate replacement of the prosthesis. This study was designed to explore the in vitro effects of Staphylococcus aureus (Sa) and Staphylococcus...

journal_title：Biomaterials

authors： Bellón JM,G-Honduvilla N,Jurado F,Carranza A,Buján J

更新日期：2001-07-01 00:00:00

abstract：:Chitosan-silica xerogel hybrid membranes were fabricated using a sol-gel process and their potential applications in guided bone regeneration (GBR) were investigated in terms of their in vitro cellular activity and in vivo bone regeneration ability. TEM observation revealed that the silica xerogel was dispersed in the...

journal_title：Biomaterials

authors： Lee EJ,Shin DS,Kim HE,Kim HW,Koh YH,Jang JH

更新日期：2009-02-01 00:00:00

abstract：:Biomaterials can potentially influence stem and progenitor cell proliferation and differentiation in both a positive and a negative way. Herein, we report on the expansion and differentiation of rat embryonic (E17) liver (RLC-18) cells on new bioactive membrane made of PEEK-WC-PU, whose surface was grafted with nitrog...

journal_title：Biomaterials

authors： Pavlica S,Piscioneri A,Peinemann F,Keller M,Milosevic J,Staeudte A,Heilmann A,Schulz-Siegmund M,Laera S,Favia P,De Bartolo L,Bader A

更新日期：2009-11-01 00:00:00

abstract：:The goal of this study was to develop a polymeric carrier for delivery of anti-tumor drugs and sustained release of these agents in order to optimize anti-tumor activity while minimizing systemic effects. We used oligo(poly(ethylene glycol) fumarate) (OPF) hydrogels modified with small negatively charged molecules, so...

journal_title：Biomaterials

authors： Dadsetan M,Liu Z,Pumberger M,Giraldo CV,Ruesink T,Lu L,Yaszemski MJ

更新日期：2010-11-01 00:00:00

abstract：:Implant surface topography influences osteoblastic proliferation, differentiation and extracellular matrix protein expressions. Studies on preliminary interactions of osteoblast-like cells on implant interface through in vitro systems, can give lucid insights to osseo-integrative efficacies of when in vivo implants. I...

journal_title：Biomaterials

authors： Jayaraman M,Meyer U,Bühner M,Joos U,Wiesmann HP

更新日期：2004-02-01 00:00:00