当前位置： SCI文献检索 > LEUKEMIA RESEARCH期刊下所有文献 > Low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor for elderly patients with previously untreated acute myeloid leukemia.

Low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor for elderly patients with previously untreated acute myeloid leukemia.

Abstract：

:We evaluated the efficacy of low-dose cytarabine and aclarubicin combined with granulocyte colony-stimulating factor (CAG) in elderly patients with previously untreated acute myeloid leukemia. Patients aged between 60 and 70 years who were not eligible for standard chemotherapy protocols and patients aged over 70 years were all registered. Thirty-three of 68 patients (49%) achieved remission. Median disease-free survival was 10 months and overall survival was nine months. Performance status after chemotherapy in patients who achieved remission was generally favorable. The present study demonstrates that CAG therapy is efficacious and well tolerated in the majority of elderly patients.

journal_name

Leuk Res

journal_title

Leukemia research

authors

Suzushima H,Wada N,Yamasaki H,Eto K,Shimomura T,Kugimiya MH,Horikawa K,Nishimura S,Tsuda H,Mitsuya H,Asou N

doi

10.1016/j.leukres.2009.08.010

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

610-4

issue

5

eissn

0145-2126

issn

1873-5835

pii

S0145-2126(09)00421-4

journal_volume

34

pub_type

临床试验,杂志文章

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