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Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system.

Abstract：

:Poly(epsilon-caprolactone)-poly(ethylene glycol) (PCL-PEG) copolymers are important synthetic biomedical materials with amphiphilicity, controlled biodegradability, and great biocompatibility. They have great potential application in the fields of nanotechnology, tissue engineering, pharmaceutics, and medicinal chemistry. This review introduced several aspects of PCL-PEG copolymers, including synthetic chemistry, PCL-PEG micro/nanoparticles, PCL-PEG hydrogels, and physicochemical and toxicological properties.

journal_name

Int J Pharm

journal_title

International journal of pharmaceutics

authors

Wei X,Gong C,Gou M,Fu S,Guo Q,Shi S,Luo F,Guo G,Qiu L,Qian Z

doi

10.1016/j.ijpharm.2009.07.033

subject

Has Abstract

pub_date

2009-10-20 00:00:00

pages

1-18

issue

1

eissn

0378-5173

issn

1873-3476

pii

S0378-5173(09)00503-1

journal_volume

381

pub_type

杂志文章,评审

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