Polymer encapsulation of inorganic nanoparticles for biomedical applications.

Abstract:

:Hybrid inorganic colloidal particles have attracted a great attention in the last years, and they have been largely used in various applications and more particularly in biomedical nanotechnology. Recently, they are used as carriers for biomolecules, and exploited for use in microsystems, microfluidics and in lab-on-a chip based bionanotechnology. Various kinds of hybrid particles can be listed starting from classical inorganic nanoparticles such as silica, gold, silver, iron oxide and those exhibiting intrinsic properties such as semiconducting nanoparticles (e.g. quantum dots). As a general tendency, to be conveniently used in biomedical applications, the encapsulation of the inorganic nanoparticles in a polymer matrix is incontestably needed. Consequently, various chemistry-based encapsulation processes have been developed and showed promising results as compared to the encapsulation using preformed polymers.

journal_name

Int J Pharm

authors

Ladj R,Bitar A,Eissa MM,Fessi H,Mugnier Y,Le Dantec R,Elaissari A

doi

10.1016/j.ijpharm.2013.09.001

subject

Has Abstract

pub_date

2013-12-15 00:00:00

pages

230-41

issue

1

eissn

0378-5173

issn

1873-3476

pii

S0378-5173(13)00836-3

journal_volume

458

pub_type

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