Expression of the macrophage antigen CD163 in rectal cancer cells is associated with early local recurrence and reduced survival time.

abstract：:Metastasis to the liver often occurs in patients during the natural course of pancreatic cancer. Using carcinoma cell lines established from 9 such patients, we examined phenotypes of cell lines to search for correlations with their potential to metastasize to the liver. Anti-asialo GMI-treated nude mice were used. PC...

journal_title：International journal of cancer

authors： Kishimoto T,Ishikura H,Kimura C,Takahashi T,Kato H,Yoshiki T

更新日期：1996-08-22 00:00:00

abstract：:History of diabetes may be associated with decreased prostate cancer (PCa) risk. Published studies have not always accounted for time since diabetes diagnosis or confounding and effect modification by lifestyle factors. The authors investigated the relationship between diabetes and PCa risk in men in the Health Profes...

journal_title：International journal of cancer

authors： Kasper JS,Liu Y,Giovannucci E

更新日期：2009-03-15 00:00:00

abstract：:Primary cultures of rat microvascular endothelial cells were transformed, in vitro, by exposure to Rous sarcoma virus. Transformed cells were followed and evaluated cytogenetically through numerous passages. Highly specific karyotypic changes in karyotype (both structural and numerical) were documented. These changes ...

journal_title：International journal of cancer

authors： Tyrkus M,Diglio CA,Gohle N

更新日期：1983-10-15 00:00:00

abstract：:Colorectal cancer (CRC) screening rates are currently suboptimal. Blood-based screening could improve rates of earlier detection for CRC and adenomatous colorectal polyps. In this study, we evaluated the feasibility of plasma-based detection of early CRC and adenomatous polyps using array-mediated analysis methylation...

journal_title：International journal of cancer

authors： Cassinotti E,Melson J,Liggett T,Melnikov A,Yi Q,Replogle C,Mobarhan S,Boni L,Segato S,Levenson V

更新日期：2012-09-01 00:00:00

abstract：:APC10.1 is a new intestinal cell line derived from ApcMin/+ mice that retains both the heterozygous Apc genotype and a nonactivated Wnt signaling pathway and displays an early neoplastic phenotype. Although tumorigenic both in immunodepressed and in immunocompetent syngeneic mice, it requires a high cell dose and a lo...

journal_title：International journal of cancer

authors： De Giovanni C,Landuzzi L,Nicoletti G,Astolfi A,Croci S,Micaroni M,Nanni P,Lollini PL

更新日期：2004-03-20 00:00:00

abstract：:The EMS1 gene encodes an 80/85 kDa c-src substrate and localises with the CCND1 gene to chromosome 11q13. This locus is amplified in approximately 13% of human breast cancers. EMS1 gene amplification and expression were characterised in a panel of human breast cancer cell lines to determine at what levels expression i...

journal_title：International journal of cancer

authors： Campbell DH,deFazio A,Sutherland RL,Daly RJ

更新日期：1996-11-15 00:00:00

abstract：:The objectives of this prospective multicentre international cohort study are to describe the characteristics of a cohort of HIV-1 positive women and determine the best management system by comparing cervical pathology according to results of cytology, colposcopy and human papillomavirus (HPV) testing at baseline and ...

journal_title：International journal of cancer

authors： Kitchener H,Nelson L,Adams J,Mesher D,Sasieni P,Cubie H,Moore C,Heard I,Agarossi A,Casolati E,Denny L,Bradbeer C,Lyons F,Beattie G,Niemiec T

更新日期：2007-12-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is an angiogenic factor that also functions as an autocrine growth factor for VEGF receptor (VEGFR)-2(+) melanomas. In multiple studies, VEGFR-2 was detected by immunostaining in 78-89% of human melanoma cells, suggesting that most patients with melanoma would benefit from an...

journal_title：International journal of cancer

authors： Molhoek KR,Erdag G,Rasamny JK,Murphy C,Deacon D,Patterson JW,Slingluff CL Jr,Brautigan DL

更新日期：2011-12-15 00:00:00

abstract：:Ultraviolet radiation, and in particular UVA (320-400 nm), induces significant oxidative stress to human skin. Ferritin and glutathione have been shown to be among the more important molecules within human skin cells providing protection against this damage, the presence of lower levels of these anti-oxidants giving r...

journal_title：International journal of cancer

authors： Applegate LA,Scaletta C,Labidi F,Vile GF,Frenk E

更新日期：1996-07-29 00:00:00

abstract：:The selective targets for HTLV-III/LAV, the causal infectious agent of AIDS and AIDS-related complex (ARC), are T4 cells, apparently because the virus receptor is associated with T4 antigen determinants. This accounts for T4 cell depletion in AIDS and for a decrease of IL-2 production by AIDS peripheral blood lymphocy...

journal_title：International journal of cancer

authors： Fouchard M,Reveil B,Mbayo K,Lurhuma A,Sarin PS,Gallo RC,Zagury D

更新日期：1986-11-15 00:00:00

abstract：:In Japan, cervical cancer incidence has increased since the late 1990s especially among young women, despite a decreasing trend in most developed countries. Here, we examined age, period and birth cohort trends in cervical cancer incidence rates from 1985 to 2012. Incidence rates were ascertained using three populatio...

journal_title：International journal of cancer

authors： Utada M,Chernyavskiy P,Lee WJ,Franceschi S,Sauvaget C,de Gonzalez AB,Withrow DR

更新日期：2019-05-01 00:00:00

abstract：:Previous literature, although not consistent, suggests that moderate alcohol consumption might be associated with decreased risk of renal cell carcinoma (RCC) in women. Thus, we examined the association between alcohol intake and the incidence of RCC by analyzing data from the Swedish Mammography Cohort, a population-...

journal_title：International journal of cancer

authors： Rashidkhani B,Akesson A,Lindblad P,Wolk A

更新日期：2005-12-10 00:00:00

abstract：:Claudin7 (cld7) is a cancer-initiating cell (CIC) marker in gastrointestinal tumors, a cld7-knockdown (kd) being accompanied by loss of tumor progression. Tumor exosomes (TEX) restoring CIC activities, we explored the contribution of cld7. This became particularly interesting, as tight junction (TJ)- and glycolipid-en...

journal_title：International journal of cancer

authors： Kyuno D,Zhao K,Schnölzer M,Provaznik J,Hackert T,Zöller M

更新日期：2019-10-15 00:00:00

abstract：:Leukemia stem cells (LSCs) might originate from malignant transformation of normal hematopoietic stem cells (HSCs), or alternatively, of progenitors in which the acquired mutations have re-installed a dysregulated self-renewal program. LSCs are on top of a hierarchy and generate leukemia cells with more differentiated...

journal_title：International journal of cancer

authors： Buss EC,Ho AD

更新日期：2011-11-15 00:00:00

abstract：:Generation of cytotoxic T lymphocytes (CTL) in vitro and tumor-rejection responses by sensitization of semi-syngeneic mice with tumor-antigen-reconstituted liposomes were investigated. Liposomes were prepared from a crude butanol extract (CBE) of BALBRVD leukemia cells and egg phosphatidylcholine (PC): 1,2-dimyristoyl...

journal_title：International journal of cancer

authors： Shibata R,Noguchi T,Sato T,Akiyoshi K,Sunamoto J,Shiku H,Nakayama E

更新日期：1991-05-30 00:00:00

abstract：:Experimental and epidemiological data support a role for sex steroid hormones in the pathogenesis of endometrial cancer. The associations of pre-diagnostic blood concentrations of estradiol, estrone, testosterone, androstenedione, DHEAS and SHBG with endometrial cancer risk were investigated. A case-control study was ...

journal_title：International journal of cancer

authors： Lukanova A,Lundin E,Micheli A,Arslan A,Ferrari P,Rinaldi S,Krogh V,Lenner P,Shore RE,Biessy C,Muti P,Riboli E,Koenig KL,Levitz M,Stattin P,Berrino F,Hallmans G,Kaaks R,Toniolo P,Zeleniuch-Jacquotte A

更新日期：2004-01-20 00:00:00

abstract：:Non-neoplastic mesenchymal cells, along with 33 benign and 87 malignant soft-tissue tumors (STT) were examined for expression of HLA-A,B,C, beta 2-microglobulin (beta 2m), HLA-DR, -DP, and -DQ molecules and the HLA-D associated invariant chain (Ii). Serial frozen sections were immunostained using monoclonal antibodies...

journal_title：International journal of cancer

authors： Mechtersheimer G,Staudter M,Majdic O,Dörken B,Moldenhauer G,Möller P

更新日期：1990-11-15 00:00:00

abstract：:Hamster embryos were exposed in utero to the action of sodium nitrite (NaNO2) and morpholine (Mo) administered simultaneously by stomach tube to the mothers on the 11th or 12th day of pregnancy. Embryo cells were examined for chromosomal aberrations, micronuclear formation, morphological or malignant transformation an...

journal_title：International journal of cancer

authors： Inui N,Nishi Y,Taketomi M,Mori M,Yamamoto M,Yamada T,Tanimura A

更新日期：1979-09-15 00:00:00

abstract：:An important feature of cytochrome P450 (CYP) 2B1 is its high ability to convert the prodrug cyclophosphamide (CPA) to therapeutically cytotoxic metabolites, resulting in interstrand DNA-cross-linking and cell death. We have examined whether and how the phosphorylation of CYP2B1 influences CPA metabolic activation in ...

journal_title：International journal of cancer

authors： Oesch-Bartlomowicz B,Richter B,Becker R,Vogel S,Padma PR,Hengstler JG,Oesch F

更新日期：2001-12-01 00:00:00

abstract：:Immune checkpoint inhibition leads to response in some patients with head and neck squamous cell carcinoma (HNSCC). Robust biomarkers are lacking to date. We analyzed viral status, gene expression signatures, mutational load and mutational signatures in whole exome and RNA-sequencing data of the HNSCC TCGA dataset (n ...

journal_title：International journal of cancer

authors： Messerschmidt C,Obermayer B,Klinghammer K,Ochsenreither S,Treue D,Stenzinger A,Glimm H,Fröhling S,Kindler T,Brandts CH,Schulze-Osthoff K,Weichert W,Tinhofer I,Klauschen F,Keilholz U,Beule D,Rieke DT

更新日期：2020-10-15 00:00:00

abstract：:The expression of the nuclear SV40-induced T antigen was measured by microfluorimetry on individual, asynchronously growing SV40-transformed cells which had been stained with hamster T-antiserum by the indirect immunofluorescence method. The same individual cells were first measured for T antigen and then for DNA by F...

journal_title：International journal of cancer

authors： Stenman S,Zeuthen J,Ringertz NR

更新日期：1975-04-15 00:00:00

abstract：:Cervical mucosal expression of cytokines involved in mediating cellular immunity is believed to influence the persistence of human papillomavirus (HPV) infection, a necessary prerequisite for the development of cervical intraepithelial neoplasia (CIN). Additionally, regulatory T (Treg) cells are increasingly understoo...

journal_title：International journal of cancer

authors： Scott ME,Ma Y,Kuzmich L,Moscicki AB

更新日期：2009-03-15 00:00:00

abstract：:Nasopharyngeal carcinoma is an Epstein-Barr Virus (EBV) associated malignancy which is highly prevalent in Southeast Asia. EBV-related antibodies have been widely used as screening markers for early nasopharyngeal carcinoma (NPC) detection. However, due to its low positive predictive rate, it is essential to develop n...

journal_title：International journal of cancer

authors： Jiang C,Chen J,Xie S,Zhang L,Xiang Y,Lung M,Kam NW,Kwong DL,Cao S,Guan XY

更新日期：2018-12-15 00:00:00

abstract：:LiSa-2 is a stable cell line derived from a poorly differentiated, pleomorphic liposarcoma. In serum-containing medium, LiSa-2 cells are fibroblastoid and rapidly dividing. In a serum-free, chemically defined culture medium containing physiological concentrations of insulin, triiodothyronine and cortisol, LiSa-2 cells...

journal_title：International journal of cancer

authors： Wabitsch M,Brüderlein S,Melzner I,Braun M,Mechtersheimer G,Möller P

更新日期：2000-12-15 00:00:00

abstract：:There are clear indications that inheritance plays an essential role in certain cases of human endometrial cancer, and there are at least 2 forms of early-onset heritable endometrial adenocarcinomas (EACs). Females of the BDII inbred rat strain are known to be genetically predisposed to endometrial carcinoma, and we h...

journal_title：International journal of cancer

authors： Roshani L,Wedekind D,Szpirer J,Taib Z,Szpirer C,Beckmann B,Rivière M,Hedrich HJ,Klinga-Levan K

更新日期：2001-12-15 00:00:00

abstract：:661 bp coding for the carboxyl end of the large sub-unit of EBV ribonucleotide reductase was cloned into the pMal plasmid vector. Purified recombinant protein was tested in IgG and IgA ELISAs. For the IgG assay, 81 out of 100 NPC patients tested positive, whereas for the IgA assay, 60 tested positive. Among 100 normal...

journal_title：International journal of cancer

authors： Fones-Tan A,Chan SH,Tsao SY,Gan LH,Tan WH,Li B,Khong PW,Gan YY

更新日期：1994-12-15 00:00:00

abstract：:A hamster lymphoid cell line, HCT-2, transformed by human T-cell leukemia virus type I (HTLV-I) was serially transplanted for 9 passages in newborn hamsters. A total of 34 newborn hamsters inoculated intraperitoneally (i.p.) with 0.2-2 X 10(7) HCT-2 cells developed fatal lymphomas with dissemination to various organs ...

journal_title：International journal of cancer

authors： Eguchi T,Kubonishi I,Daibata M,Yano S,Imamura J,Ohtsuki Y,Miyoshi I

更新日期：1988-06-15 00:00:00

abstract：:Genetic and epigenetic alterations during development of pancreatic ductal adenocarcinomas (PDACs) are well known. This study investigates genetic and epigenetic data together with tumor biology to find specific alterations responsible for metastasis formation. Using 16 human PDAC cell lines in a murine orthotopic PDA...

journal_title：International journal of cancer

authors： Mees ST,Mardin WA,Wendel C,Baeumer N,Willscher E,Senninger N,Schleicher C,Colombo-Benkmann M,Haier J

更新日期：2010-01-01 00:00:00

abstract：:Sera samples from 111 women, including 73 breast cancer patients and 38 patients with benign diseases of the breast, were examined. These were compared with samples from healthy women or from patients carrying tumors of origin other than breast as controls. This was done to determine whether antibodies against GCDFP-1...

journal_title：International journal of cancer

authors： Pasquinelli R,Barba P,Capasso I,D'Aiuto M,D'Aiuto G,Anzisi AM,De Berardinis P,Guardiola J

更新日期：1999-12-22 00:00:00

abstract：:Melanocortin-1 receptor (MC1R) is a marker of melanoma risk in populations of European ancestry. However, MC1R effects on survival are much less studied. We investigated associations between variation at MC1R and survival in an international, population-based series of single primary melanoma patients enrolled into th...

journal_title：International journal of cancer

authors： Taylor NJ,Reiner AS,Begg CB,Cust AE,Busam KJ,Anton-Culver H,Dwyer T,From L,Gallagher RP,Gruber SB,Rosso S,White KA,Zanetti R,Orlow I,Thomas NE,Rebbeck TR,Berwick M,Kanetsky PA,GEM Study Group.

更新日期：2015-06-01 00:00:00