Semantic fluency: a sensitive marker for cognitive impairment in children with heavy diarrhea burdens?

Abstract:

:One of the most affected cognitive impairments in children who experienced heavy burdens of diarrhea is semantic fluency, the same impairment that is most affected in Alzheimer's dementia. These findings are leading us into provocative genetic studies that may elucidate the evolution of such genetic polymorphisms as the APOE alleles. Alternatively, diarrhea could launch the cognitive deficits that might later progress in neurodegenerative diseases. In addition, they suggest that semantic fluency could provide a simple mean to assess cognitive impairment in impoverished settings so as to determine preventive measures.

journal_name

Med Hypotheses

journal_title

Medical hypotheses

authors

Oriá RB,Costa CM,Lima AA,Patrick PD,Guerrant RL

doi

10.1016/j.mehy.2009.05.013

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

682-6

issue

5

eissn

0306-9877

issn

1532-2777

pii

S0306-9877(09)00344-2

journal_volume

73

pub_type

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