Passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated.

abstract：:Previously, we identified five genes (Cj1321 to Cj1326, of which Cj1325 and Cj1326 are a single gene) in the O-linked flagellin glycosylation island that are highly prevalent in Campylobacter jejuni isolates from chickens. We report mutagenesis, functional, and structural data to confirm that this locus, and Cj1324 in...

journal_title：Infection and immunity

authors： Howard SL,Jagannathan A,Soo EC,Hui JP,Aubry AJ,Ahmed I,Karlyshev A,Kelly JF,Jones MA,Stevens MP,Logan SM,Wren BW

更新日期：2009-06-01 00:00:00

abstract：:Salmonella serovars are associated with human diseases that range from mild gastroenteritis to host-disseminated enteric fever. Human infections by Salmonella enterica serovar Typhi can lead to typhoid fever, but this serovar does not typically cause disease in mice or other animals. In contrast, S. enterica serovar T...

journal_title：Infection and immunity

authors： Schwan WR,Huang XZ,Hu L,Kopecko DJ

更新日期：2000-03-01 00:00:00

abstract：:The intestinal mucosa forms the first line of defense against infections mediated by enteric pathogens such as salmonellae. Here we exploited intestinal "organoids" (iHOs) generated from human induced pluripotent stem cells (hIPSCs) to explore the interaction of Salmonella enterica serovar Typhimurium with iHOs. Imagi...

journal_title：Infection and immunity

authors： Forbester JL,Goulding D,Vallier L,Hannan N,Hale C,Pickard D,Mukhopadhyay S,Dougan G

更新日期：2015-07-01 00:00:00

abstract：:In vitro studies have shown that enterotoxigenic Escherichia coli (ETEC) strains are capable of invading cultured epithelial cells derived from the human ileum and colon. Two separate invasion loci (tia and tib) have previously been isolated from the classical ETEC strain H10407. The tia locus has been shown to direct...

journal_title：Infection and immunity

authors： Mammarappallil JG,Elsinghorst EA

更新日期：2000-12-01 00:00:00

abstract：:Polyprotein allergens are a family of structurally homologous molecules from parasitic nematodes which induce specific immunoglobulin E in infected individuals. We show here that both H-2 and non-H-2 factors determine the ability of mice to generate T- and B-cell responses to the filarial polyprotein allergen (Brugia ...

journal_title：Infection and immunity

authors： Allen JE,Lawrence RA,Maizels RM

更新日期：1995-08-01 00:00:00

abstract：:The adherence of several strains of Escherichia coli to human buccal epithelial cells was studied, using cells obtained from five groups: healthy adults, healthy children, children with acute diarrhea, children with persistent diarrhea associated with cryptosporidial parasites, and children with noncryptosporidial per...

journal_title：Infection and immunity

authors： Walser BL,Newman RD,Lima AA,Guerrant RL

更新日期：1992-11-01 00:00:00

abstract：:A panel of monoclonal antibodies (MAbs) specific for the heat-stable enterotoxin (STh) of enterotoxigenic Escherichia coli was produced. All four MAbs (8G7, 53-4, 11C, and SH1) bound to native STh in an enzyme-linked immunosorbent assay to various degrees, with clone SH1 showing the best affinity. The MAbs were screen...

journal_title：Infection and immunity

authors： Takeda T,Nair GB,Suzuki K,Zhe HX,Yokoo Y,De Mol P,Hemelhof W,Butzler JP,Takeda Y,Shimonishi Y

更新日期：1993-01-01 00:00:00

abstract：:Protective immunity to Plasmodium falciparum malaria acquired after natural exposure is largely antibody mediated. IgG-specific P. falciparum EMP1 (PfEMP1) proteins on the infected erythrocyte surface are particularly important. The transient antibody responses and the slowly acquired protective immunity probably refl...

journal_title：Infection and immunity

authors： Ampomah P,Stevenson L,Ofori MF,Barfod L,Hviid L

更新日期：2014-05-01 00:00:00

abstract：:The nucleotide sequences of three previously undescribed Pseudomonas aeruginosa pilin structural genes are presented. Comparisons of deduced pilin primary structure and flanking DNA sequence allowed placement of these and six previously published sequences into one of two groups. Epitope mapping, using overlapping imm...

journal_title：Infection and immunity

authors： Castric PA,Deal CD

更新日期：1994-02-01 00:00:00

abstract：:A multigene family of 58- to 60-kDa proteins, which are designated rhoptry-associated protein 1 (RAP-1) and which come from the parasites Babesia bigemina and Babesia bovis, is a target for vaccine development. The presence of multiple gene copies and conserved sequences and epitopes of RAP-1 implies that these protei...

journal_title：Infection and immunity

authors： Rodríguez SD,Palmer GH,McElwain TF,McGuire TC,Ruef BJ,Chitko-McKown MG,Brown WC

更新日期：1996-06-01 00:00:00

abstract：:Normal bacteria can translocate (migrate) across an intact intestinal mucosa, but the anatomical site of bacterial translocation has not been defined. Gastrointestinal (GI) cross-sections were obtained from mice monoassociated with high cecal concentrations of Escherichia coli, Proteus mirabilis, or Enterococcus faeca...

journal_title：Infection and immunity

authors： Wells CL,Erlandsen SL

更新日期：1991-12-01 00:00:00

abstract：:The hemolytic activity of the thermostable direct hemolysin produced by Vibrio parahaemolyticus was inhibited by a ganglioside mixture. The ganglioside component which inhibited the hemolysin was not FM1 ganglioside. ...

journal_title：Infection and immunity

authors： Takeda R,Honda T,Sakural J,Otomo N

更新日期：1975-10-01 00:00:00

abstract：:Human serum at low concentrations inhibits the growth of Cryptococcus neoformans in vitro. Fractionation of serum yielded a purified inhibitory protein with a molecular mass of approximately 81.8 kDa, a pI of approximately 6.2, and an amino acid sequence that matched that of human transferrin. The inhibitory activity ...

journal_title：Infection and immunity

authors： Sridhar S,Ahluwalia M,Brummer E,Stevens DA

更新日期：2000-06-01 00:00:00

abstract：:A number of studies have substantiated the pivotal role of innate defense mechanisms in protection against invasive aspergillosis. However, experiments demonstrating increased resistance to lethal intravenous (i.v.) infection with Aspergillus fumigatus conidia in cortisone-treated or untreated mice preinfected with a ...

journal_title：Infection and immunity

authors： de Repentigny L,Petitbois S,Boushira M,Michaliszyn E,Sénéchal S,Gendron N,Montplaisir S

更新日期：1993-09-01 00:00:00

abstract：:The gene encoding the 35-kDa immunogenic Treponema pallidium subsp. pallidum (T. pallidum) membrane protein C, TmpC, was cloned, sequenced, and expressed in Escherichia coli. The deduced amino acid sequence carries on N-terminal signal sequence with a four-amino-acid motif, which is characteristic for bacterial lipopr...

journal_title：Infection and immunity

authors： Schouls LM,van der Heide HG,van Embden JD

更新日期：1991-10-01 00:00:00

abstract：:Human opsonins directed against specific meningococcal outer membrane structures in sera obtained during meningococcal disease were quantified with a recently developed antigen-specific, opsonin-dependent phagocytosis and oxidative burst assay. Outer membrane vesicles (OMVs) and PorA (class 1) and PorB (class 3) prote...

journal_title：Infection and immunity

authors： Lehmann AK,Halstensen A,Aaberge IS,Holst J,Michaelsen TE,Sornes S,Wetzler LM,Guttormsen H

更新日期：1999-05-01 00:00:00

abstract：:The biological response to endotoxin mediated through the Toll-like receptor 4 (TLR4)-MD-2 receptor complex is directly related to lipid A structure or configuration. Endotoxin structure may also influence activation of the MyD88-dependent and -independent signaling pathways of TLR4. To address this possibility, human...

journal_title：Infection and immunity

authors： Zughaier SM,Zimmer SM,Datta A,Carlson RW,Stephens DS

更新日期：2005-05-01 00:00:00

abstract：:Since melanin is considered a virulence factor in Cryptococcus neoformans, its suppression at 37 degrees C has been perplexing. We now show an opposite thermal regulation of superoxide dismutase (SOD), consistent with a compensatory mechanism. Moreover, we demonstrate normal SOD and catalase levels in albino, oxygen-s...

journal_title：Infection and immunity

authors： Jacobson ES,Jenkins ND,Todd JM

更新日期：1994-09-01 00:00:00

abstract：:Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn's disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10-deficient mice dev...

journal_title：Infection and immunity

authors： Ellermann M,Gharaibeh RZ,Fulbright L,Dogan B,Moore LN,Broberg CA,Lopez LR,Rothemich AM,Herzog JW,Rogala A,Gordon IO,Rieder F,Brouwer CR,Simpson KW,Jobin C,Sartor RB,Arthur JC

更新日期：2019-10-18 00:00:00

abstract：:Numerous bacterial pathogens use type III secretion systems (T3SSs) or T4SSs to inject or translocate virulence proteins into eukaryotic cells. Several different reporter systems have been developed to measure the translocation of these proteins. In this study, a peptide tag-based reporter system was developed and use...

journal_title：Infection and immunity

authors： Garcia JT,Ferracci F,Jackson MW,Joseph SS,Pattis I,Plano LR,Fischer W,Plano GV

更新日期：2006-10-01 00:00:00

abstract：:Hookworm glutathione S-transferases (GSTs) are critical for parasite blood feeding and survival and represent potential targets for vaccination. Three cDNAs, each encoding a full-length GST protein from the human hookworm Necator americanus (and designated Na-GST-1, Na-GST-2, and Na-GST-3, respectively) were isolated ...

journal_title：Infection and immunity

authors： Zhan B,Perally S,Brophy PM,Xue J,Goud G,Liu S,Deumic V,de Oliveira LM,Bethony J,Bottazzi ME,Jiang D,Gillespie P,Xiao SH,Gupta R,Loukas A,Ranjit N,Lustigman S,Oksov Y,Hotez P

更新日期：2010-04-01 00:00:00

abstract：:Vibrio cholerae neuraminidase (NANase) is hypothesized to act synergistically with cholera toxin (CT) and increase the severity of a secretory response by increasing the binding and penetration of CT to enterocytes. To test this hypothesis, the NANase gene (nanH) from V. cholerae Ogawa 395 was first cloned and sequenc...

journal_title：Infection and immunity

authors： Galen JE,Ketley JM,Fasano A,Richardson SH,Wasserman SS,Kaper JB

更新日期：1992-02-01 00:00:00

abstract：:Randomly bred guinea pigs were infected with Listeria monocytogenes using the intracardial, intravenous and intraperitoneal routes of infection. Doses of Listeria ranged from 5 to 1,000 x the 50% lethal dose based on the 50% lethal dose for intracardially injected Listeria. A complete necropsy was performed on all ani...

journal_title：Infection and immunity

authors： Dustoor M,Croft W,Fulton A,Blazkovec A

更新日期：1977-03-01 00:00:00

abstract：:The kinetics of infection and the pathogenic effects on the reproductive function of laboratory mice infected with Bartonella birtlesii recovered from an Apodemus species are described. B. birtlesii infection, as determined by bacteremia, occurred in BALB/c mice inoculated intravenously. Inoculation with a low-dose in...

journal_title：Infection and immunity

authors： Boulouis HJ,Barrat F,Bermond D,Bernex F,Thibault D,Heller R,Fontaine JJ,Piémont Y,Chomel BB

更新日期：2001-09-01 00:00:00

abstract：:The effects of tolerance to Escherichia coli endotoxin on the phagocytic and bactericidal activity of the hepatic reticuloendothelial system against viable E. coli were examined using ex vivo perfused rat livers. Livers were isolated from control and endotoxin-tolerant rats and perfused with a medium containing 5% hom...

journal_title：Infection and immunity

authors： Ruggiero G,Andreana A,Utili R,Galante D

更新日期：1980-03-01 00:00:00

abstract：:The Pseudomonas aeruginosa quorum-sensing systems, las and rhl, control the production of numerous virulence factors. In this study, we have used the burned-mouse model to examine the contribution of quorum-sensing systems to the pathogenesis of P. aeruginosa infections in burn wounds. Different quorum-sensing mutants...

journal_title：Infection and immunity

authors： Rumbaugh KP,Griswold JA,Iglewski BH,Hamood AN

更新日期：1999-11-01 00:00:00

abstract：:The facultative intracellular bacterial pathogen Listeria monocytogenes induces severe fetal infection during pregnancy. Little is known about the molecular mechanisms allowing the maternofetal transmission of bacteria. In this work, we studied fetoplacental invasion by infecting mice with various mutants lacking viru...

journal_title：Infection and immunity

authors： Le Monnier A,Autret N,Join-Lambert OF,Jaubert F,Charbit A,Berche P,Kayal S

更新日期：2007-02-01 00:00:00

abstract：:Antigens were extracted from a virulent isolate of Pasteurella multocida (serotype 3, 12, 15:D) with potassium thiocyanate, and a vaccine was prepared. Pasteurella-free rabbits were vaccinated intranasally and intraconjuctivally twice with a 2-week interval and challenged intranasally with the homologous P. multocida ...

journal_title：Infection and immunity

authors： Ringler DH,Peter GK,Chrisp CE,Keren DF

更新日期：1985-09-01 00:00:00

abstract：:The microfilament inhibitors cytochalasins B and D have been traditionally used to indirectly evaluate the requirement for actin in the uptake of invasive bacterial pathogens by nonprofessional phagocytes. Through their effects on microfilaments, both cytochalasins also impart profound alterations in cellular morpholo...

journal_title：Infection and immunity

authors： Ewanowich CA,Peppler MS

更新日期：1990-10-01 00:00:00

abstract：:Trypanosoma brucei subsp. brucei and T. congolense incubated in homologous antibody at 0 degrees C for 30 min were lysed by subsequent addition of guinea pig complement. Trypanosomes incubated in antibody at 37 degrees C before complement treatment remained intact. Parasites bearing adsorbed antibody also remained int...

journal_title：Infection and immunity

authors： Balber AE,Bangs JD,Jones SM,Proia RL

更新日期：1979-06-01 00:00:00