Differences between smooth pursuit and optokinetic eye movements using limited lifetime dot stimulation: a functional magnetic resonance imaging study.

Abstract:

:In this study, we examined possible differences in brain activation between smooth pursuit and optokinetic reflexive (OKR) eye movements using functional magnetic resonance imaging (fMRI). Eighteen healthy subjects performed two different eye movement paradigms. In the first paradigm, smooth pursuit eye movements were evoked by a single moving dot. In the second paradigm, optokinetic eye movements without a foveal smooth pursuit component were evoked by a moving pattern of multiple dots with a limited lifetime. As expected, the two eye movement systems show overlapping pathways, but the direct comparison of the activation patterns between the two experiments showed that the frontal eye field, MT/V5 and cerebellar area VI appear to be more activated during smooth pursuit than during optokinetic eye movements. These results showed that the smooth pursuit and optokinetic eye movement systems can be differentiated with fMRI using limited lifetime dots as an effective OKR stimulus.

authors

Schraa-Tam CK,van der Lugt A,Smits M,Frens MA,van Broekhoven PC,van der Geest JN

doi

10.1111/j.1475-097X.2009.00858.x

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

245-54

issue

4

eissn

1475-0961

issn

1475-097X

pii

CPF858

journal_volume

29

pub_type

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