Low flow-mediated constriction: prevalence, impact and physiological determinant.

Abstract:

:Flow-mediated dilation (FMD) is a surrogate marker for endothelial function. In the FMD procedure, arterial response during cuff inflation is not taken into consideration yet studies have demonstrated vasoconstriction, vasodilation and no change in the brachial artery during cuff inflation. The term low flow-mediated constriction (L-FMC) has been introduced to describe the vasoconstriction that occurs in some individuals during inflation of the cuff. The aims of this study were to examine (i) whether brachial artery response during cuff inflation differed in a population with varied coronary artery disease (CAD) risk factor profiles, (ii) the impact of this response on the subsequent calculation of FMD and (iii) the role of arterial stiffness in this variable response. L-FMC, 'traditional' FMD and 'modified' FMD, which accounts for brachial artery response during cuff inflation, were studied in a total of 46 subjects varying in risk factor profiles for coronary artery disease. During cuff inflation, brachial artery responses varied widely from -5·6% (vasoconstriction) to 5·0% (vasodilation). When subjects were divided into healthy versus multiple risk factors (n = 34), L-FMC and FMD were not different between the groups but modified FMD was significantly different (P = 0·02). L-FMC was modestly but significantly associated with FMD (r = 0·41) and positively correlated with brachial artery pulse wave velocity (r = 0·30). Our results indicate that brachial artery responses to inflation of the cuff are very variable and are associated with arterial stiffness and that accounting for so-called L-FMC may provide a more comprehensive assessment of endothelial vasodilatory function.

authors

Harrison M,Parkhurst K,Tarumi T,Lin HF,Tanaka H

doi

10.1111/j.1475-097X.2011.01032.x

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

394-8

issue

5

eissn

1475-0961

issn

1475-097X

journal_volume

31

pub_type

杂志文章
  • Acute effects of proprioceptive neuromuscular facilitation and static stretching on maximal voluntary contraction and muscle electromyographical activity in indoor soccer players.

    abstract::The aim was to investigate and compare the effects of proprioceptive neuromuscular facilitation (PNF) and static stretching (SS) on maximal voluntary contraction (MVC) and muscle activation in indoor soccer players. Thirty-three young adult men were divided into two groups: (i) sedentary and (ii) trained. Each group c...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12047

    authors: Reis Eda F,Pereira GB,de Sousa NM,Tibana RA,Silva MF,Araujo M,Gomes I,Prestes J

    更新日期:2013-11-01 00:00:00

  • Automatic T2* determination for quantification of iron load in heart and liver: a comparison between automatic inline Maximum Likelihood Estimate and the truncation and offset methods.

    abstract:PURPOSE:To validate ironload T2* by automatic inline Maximum Likelihood Estimate (MLE) with k-space Rician noise correction, against the manual and automated truncation, as well as offset methods, in phantoms and in heart and liver in patients. METHODS:Twenty-five patients and an iron-oxide phantom were scanned at 1.5...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12303

    authors: Hedström E,Voigt T,Greil G,Schaeffter T,Nagel E

    更新日期:2017-05-01 00:00:00

  • Influence of reconstruction algorithms on image quality in SPECT myocardial perfusion imaging.

    abstract:INTRODUCTION:We investigated if image- and diagnostic quality in SPECT MPI could be maintained despite a reduced acquisition time adding Depth Dependent Resolution Recovery (DDRR) for image reconstruction. Images were compared with filtered back projection (FBP) and iterative reconstruction using Ordered Subsets Expect...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12354

    authors: Davidsson A,Olsson E,Engvall J,Gustafsson A

    更新日期:2017-11-01 00:00:00

  • Detection of chronic rejection by quantitative ventilation scintigrams in lung-transplanted patients: a pilot study.

    abstract::The suspicion of chronic rejection [bronchiolithis obliterans syndrome (BOS)] is usually based on deteriorating forced expired volume in 1 s. It is however, desirable to develop more sensitive methods as increased anti-inflammatory therapy is thought to stop progression of the rejection. The aim of the present study w...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2005.00609.x

    authors: Johansson A,Moonen M,Enocson A,Mårtensson G,Bake B

    更新日期:2005-05-01 00:00:00

  • Computer-assisted calculation of myocardial infarct size shortens the evaluation time of contrast-enhanced cardiac MRI.

    abstract:BACKGROUND:Delayed enhancement magnetic resonance imaging depicts scar in the left ventricle which can be quantitatively measured. Manual segmentation and scar determination is time consuming. The purpose of this study was to evaluate a software for infarct quantification, to compare with manual scar determination, and...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2007.00765.x

    authors: Rosendahl L,Blomstrand P,Heiberg E,Ohlsson J,Björklund PG,Ahlander BM,Engvall J

    更新日期:2008-01-01 00:00:00

  • Myocardial CT perfusion compared with transthoracic Doppler echocardiography in evaluation of the coronary microvascular function: An iPOWER substudy.

    abstract:BACKGROUND:A significant number of women with angina and no obstructive coronary artery disease (CAD; <50% stenosis) have coronary microvascular dysfunction (CMD) which carries an adverse cardiovascular prognosis. Coronary microvascular function can be evaluated by transthoracic Doppler echocardiography (TTDE) as a cor...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12669

    authors: Bechsgaard DF,Hove JD,Michelsen MM,Mygind ND,Pena A,Hansen PR,Hansen HS,Kastrup J,Høst N,Gustafsson I,Prescott E

    更新日期:2021-01-01 00:00:00

  • Lumbar bone mineral content and density measured using a Lunar DPX densitometer in healthy full-term infants during the first year of life.

    abstract::This cross-sectional study provides values for lumbar spine bone mineral content (BMC) and density (BMD) in 41 healthy full-term born Finnish infants, 19 boys and 22 girls, during the first year of life measured by dual energy X-ray absorptiometry (DXA) using the Lunar DPX densitometer. Lumbar BMC correlated with the ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1046/j.1475-097x.2002.00422.x

    authors: Kurl S,Heinonen K,Jurvelin JS,Länsimies E

    更新日期:2002-05-01 00:00:00

  • Urea clearance: a new method to register local changes in blood flow in rat skeletal muscle based on microdialysis.

    abstract:SUMMARY:Increasing evidence suggests that local blood flow should be monitored during microdialysis (MD) as the recovery of analytes is affected by local blood flow. At present ethanol clearance is the standard technique for this purpose, but it is not functional at very low perfusion velocities. Here, we introduce a t...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2009.00904.x

    authors: Farnebo S,Samuelsson A,Henriksson J,Karlander LE,Sjöberg F

    更新日期:2010-01-01 00:00:00

  • Effects of different periods of hypoxic training on glucose metabolism and insulin sensitivity.

    abstract::This study examined the effects of different periods of hypoxic training on glucose metabolism. Sedentary subjects underwent hypoxic training (FiO2 = 15.0%) for either 2 weeks (2-week group; n = 11) or 4 weeks (4-week group; n = 10). The 2-week group conducted training sessions on 6 days week(-1) for 2 weeks, whereas ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/cpf.12133

    authors: Morishima T,Hasegawa Y,Sasaki H,Kurihara T,Hamaoka T,Goto K

    更新日期:2015-03-01 00:00:00

  • An assessment of pulmonary function testing and ventilatory kinematics by optoelectronic plethysmography.

    abstract::New advances in computer processing and imaging have allowed the development of innovative techniques to assess lung function. A promising methodology is optoelectronic plethysmography (OEP). OEP evaluates ventilatory kinematics through the use of infrared imaging. Markers are placed, and images read on the chest, bac...

    journal_title:Clinical physiology and functional imaging

    pub_type: 历史文章,杂志文章,评审

    doi:10.1111/j.1475-097X.2011.01028.x

    authors: Layton AM,Garber CE,Basner RC,Bartels MN

    更新日期:2011-09-01 00:00:00

  • Comparison of hand-to-hand bioimpedance and anthropometry equations versus dual-energy X-ray absorptiometry for the assessment of body fat percentage in 17-18-year-old conscripts.

    abstract::In the present study, hand-to-hand bioelectrical impedance analysis (BIA), skinfold (SKF) thickness and height-weight (body mass index, BMI)-based equations and dual-energy X-ray absorptiometry (DEXA), as a criterion method, were compared with each other in the assessment of body fat percentage (BF%) in 17-18-year-old...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2004.00534.x

    authors: Lintsi M,Kaarma H,Kull I

    更新日期:2004-03-01 00:00:00

  • Acoustic effects of positive end-expiratory pressure on normal lung sounds in mechanically ventilated pigs.

    abstract::Computerized lung sounds analysis offers a new technique to monitor regional ventilation during spontaneous breathing. The purpose of the present study was to assess the acoustic behaviour of the respiratory system in healthy pigs during mechanical ventilation when a positive end-expiratory pressure (PEEP) is applied....

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2005.00652.x

    authors: Vena A,Perchiazzi G,Giuliani R,Fiore T,Hedenstierna G

    更新日期:2006-01-01 00:00:00

  • Myocardial uptake of bone scintigraphic agents associated with increased pulmonary uptake.

    abstract:OBJECTIVE:Due to delivery problems with the most commonly used bone scintigraphic agent medronate-(99m)Tc-methylene diphosphonate (MDP) (medronate), several regional institutions changed, at various time points, to (99m)Tc-dicarboxypropane diphosphonate (DPD) (Teceos) from 2010. Extraosseous uptake, in particular, myoc...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12219

    authors: Bach-Gansmo T,Wien TN,Løndalen A,Halvorsen E

    更新日期:2016-05-01 00:00:00

  • Perfusion heterogeneity does not explain excess muscle oxygen uptake during variable intensity exercise.

    abstract::The association between muscle oxygen uptake (VO(2)) and perfusion or perfusion heterogeneity (relative dispersion, RD) was studied in eight healthy male subjects during intermittent isometric (1 s on, 2 s off) one-legged knee-extension exercise at variable intensities using positron emission tomography and a-v blood ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1475-097X.2010.00934.x

    authors: Laaksonen MS,Björklund G,Heinonen I,Kemppainen J,Knuuti J,Kyröläinen H,Kalliokoski KK

    更新日期:2010-07-01 00:00:00

  • Effect of body position on foot and ankle volume in healthy subjects.

    abstract::Physical therapy treatments for and evaluation of lower limb swelling are usually performed in supine lying position. However, the limb is usually treated or assessed in the dependent position, i.e. sitting or standing. The purpose of this study was to determine the possible confounding effect of subject positioning o...

    journal_title:Clinical physiology and functional imaging

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1475-097X.2004.00578.x

    authors: Man IO,Glover K,Nixon P,Poyton R,Terre R,Morrissey MC

    更新日期:2004-11-01 00:00:00

  • Cardiac imaging in patients with chronic liver disease.

    abstract::Cirrhotic cardiomyopathy (CCM) is characterized by an impaired contractile response to stress, diastolic dysfunction and the presence of electrophysiological abnormalities, and it may be diagnosed at rest in some patients or demasked by physiological or pharmacological stress. CCM seems to be involved in the developme...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,评审

    doi:10.1111/cpf.12311

    authors: Wiese S,Hove JD,Møller S

    更新日期:2017-07-01 00:00:00

  • Impact of abnormal cerebrovascular reactivity on BOLD fMRI: a preliminary investigation of moyamoya disease.

    abstract::Blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) studies of patients with cerebrovascular disease have largely ignored the confounds associated with abnormal cerebral blood flow, vascular reactivity and neurovascular coupling. We studied BOLD fMRI activation and cerebrovascular reactivi...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12387

    authors: Mazerolle EL,Ma Y,Sinclair D,Pike GB

    更新日期:2018-01-01 00:00:00

  • Use of temperature alterations to characterize vascular reactivity.

    abstract::Monitoring alterations in fingertip temperature during ischaemia and the subsequent hyperaemia provides a novel way of studying microvascular reactivity. The relations between parameters characterizing blood perfusion and the thermal response of fingertips were studied using experimental and theoretical approaches. Du...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2010.00981.x

    authors: Ley O,Dhindsa M,Sommerlad SM,Barnes JN,Devan AE,Naghavi M,Tanaka H

    更新日期:2011-01-01 00:00:00

  • Assessment of the upper body contribution to multiple-sprint cycling in men and women.

    abstract::The aim of this study was to investigate the effect of repeated cycling sprints on power profiles while assessing upper body muscle contraction. Eighteen physically active participants performed 8 × 10 s repeated sprints while muscle activity was recorded via surface electromyography (sEMG) from the brachioradialis (B...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12159

    authors: Grant MC,Watson H,Baker JS

    更新日期:2015-07-01 00:00:00

  • Gender variability in electromyographic activity, in vivo behaviour of the human gastrocnemius and mechanical capacity during the take-off phase of a countermovement jump.

    abstract:PURPOSE:The purpose of this study was to analyse gender differences in neuromuscular behaviour of the gastrocnemius and vastus lateralis during the take-off phase of a countermovement jump (CMJ), using direct measures (ground reaction forces, muscle activity and dynamic ultrasound). METHODS:Sixty-four young adults (ag...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12369

    authors: Rubio-Arias JÁ,Ramos-Campo DJ,Peña Amaro J,Esteban P,Mendizábal S,Jiménez JF

    更新日期:2017-11-01 00:00:00

  • Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?

    abstract:BACKGROUND:Many patients with pulmonary hypertension (PH) have symptoms of angina without evidence of occlusive coronary artery disease. For the first time, this study addresses the influence of progressively increasing pulmonary artery pressure (PAP) on left anterior descending artery flow in a rat model of PH. The ro...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2011.01049.x

    authors: Koskenvuo JW,Mirsky R,Zhang Y,Helenius H,Angeli FS,De Marco T,Boyle AJ,Yeghiazarians Y

    更新日期:2011-11-01 00:00:00

  • High-intensity interval training using whole-body exercises: training recommendations and methodological overview.

    abstract::HIIT whole body (HWB)-based exercise is a new calisthenics exercise programme approach that can be considered an effective and safe method to improve physical fitness and body composition. HWB is a method that can be applied to different populations and ages. The purpose of this study was to describe possible methodol...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,评审

    doi:10.1111/cpf.12433

    authors: Machado AF,Baker JS,Figueira Junior AJ,Bocalini DS

    更新日期:2019-11-01 00:00:00

  • Validity and interobserver agreement of lower extremity local tissue water measurements in healthy women using tissue dielectric constant.

    abstract:BACKGROUND:Tissue dielectric constant (TDC) measurement may become an important tool in the clinical evaluation of chronic lower extremity swelling in women; however, several factors are known to influence TDC measurements, and comparative data on healthy lower extremities are few. METHODS:Thirty-four healthy women vo...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2012.01129.x

    authors: Jensen MR,Birkballe S,Nørregaard S,Karlsmark T

    更新日期:2012-07-01 00:00:00

  • Vascular ultrasound for monitoring of inflammatory activity in Takayasu arteritis.

    abstract:BACKGROUND:Takayasu arteritis (TA) is a rare large-vessel arteritis that primarily affects the aorta and its major branches. The aim of this study was to describe the value of high frequency ultrasound for monitoring of inflammatory activity. METHODS:Twenty-five patients, range 11-71 years, diagnosed with TA were inve...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12601

    authors: Svensson C,Eriksson P,Zachrisson H

    更新日期:2020-01-01 00:00:00

  • Agreement between ultrasound and dual-energy X-ray absorptiometry in assessing percentage body fat in college-aged adults.

    abstract:BACKGROUND:The BodyMetrix(®) BX-2000 Ultrasound device (ULTRA) shows prowess in being an effective alternative to the expense and technicality of dual-energy X-ray absorptiometry (DXA). However, this technique has not been investigated using a seven-site methodology. SUBJECT/OBJECTIVE:To employ a cross-over design to ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12150

    authors: Johnson KE,Miller B,Juvancic-Heltzel JA,Agnor SE,Kiger DL,Kappler RM,Otterstetter R

    更新日期:2014-11-01 00:00:00

  • The influence of athletic status on maximal and rapid isometric torque characteristics and postural balance performance in Division I female soccer athletes and non-athlete controls.

    abstract::The purpose of this study was to examine the effectiveness of maximal and rapid isometric torque characteristics of the hip extensor muscles and postural balance performance to discriminate between female collegiate soccer athletes and non-athlete controls. Ten athletes (mean ± SE: age = 19·20 ± 0·36 year; mass = 62·2...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12167

    authors: Palmer TB,Hawkey MJ,Thiele RM,Conchola EC,Adams BM,Akehi K,Smith DB,Thompson BJ

    更新日期:2015-07-01 00:00:00

  • Signal-morphology impedance cardiography during incremental cardiopulmonary exercise testing in pulmonary arterial hypertension.

    abstract:BACKGROUND:Haemodynamic responses to exercise are related to physical impairment and worse prognosis in patients with pulmonary arterial hypertension (PAH). It is clinically relevant, therefore, to investigate the practical usefulness of non-invasive methods of monitoring exercise haemodynamics in this patient populati...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2012.01135.x

    authors: Ferreira EM,Ota-Arakaki JS,Barbosa PB,Siqueira AC,Bravo DM,Kapins CE,Silva CM,Nery LE,Neder JA

    更新日期:2012-09-01 00:00:00

  • Relationship between plasma volume and essential blood constituents in patients with heart failure and preserved ejection fraction.

    abstract:INTRODUCTION:Notwithstanding recent progress on molecular mechanisms underlying heart failure with preserved ejection fraction (HFpEF), multiple pathophysiological aspects of this condition including the basis of anaemia and other haematological disorders remain unresolved. In this study, we sought to determine the rel...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12614

    authors: Diaz-Canestro C,Haider T,Lundby C,Montero D

    更新日期:2020-03-01 00:00:00

  • Cerebral perfusion information obtained by dynamic contrast-enhanced phase-shift magnetic resonance imaging: comparison with model-free arterial spin labelling.

    abstract::Phase-shift time curves following a bolus injection of gadolinium contrast agent were registered for grey-matter regions and large vessels in 14 subjects. Deconvolving a tissue phase-shift curve with a phase-based arterial input function resulted in a tissue residue function R(t). The peak value of R(t) provided a rel...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2010.00947.x

    authors: Wirestam R,Lindgren E,van Westen D,Bloch KM,Ståhlberg F,Knutsson L

    更新日期:2010-09-01 00:00:00

  • Acute effects of resistance training on cytokines and osteoprotegerin in women with metabolic syndrome.

    abstract::Chronic inflammation has been identified as an important component of metabolic syndrome (MetS). Inhibition of the inflammatory mediator signals is a promising strategy against insulin resistance, atherosclerosis and other problems associated with MetS. Regular exercise decreases the components associated with MetS, i...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12004

    authors: Pereira GB,Tibana RA,Navalta J,Sousa NM,Córdova C,Souza VC,Nóbrega OT,Prestes J,Perez SE

    更新日期:2013-03-01 00:00:00