Uteroferrin contains complex and high mannose-type oligosaccharides when synthesized in vitro.

abstract：:delta-Crystallin is a major structural protein of avian and reptilian lenses that is absent from the lenses of fish, amphibia and mammals. It appears to be a tetrameric protein with a native molecular weight near 200 000 (200K) and polypeptide molecular weight near 50K and 48K) (see Note added in proof). The alpha-cry...

journal_title：Molecular and cellular biochemistry

authors： Piatigorsky J

更新日期：1984-01-01 00:00:00

abstract：:Activation of extracellular signal-related kinase (ERK) is involved in decreased melanogenesis by sphingosylphosphorylcholine (SPC). In the present study, we confirmed that SPC activated ERK and that a specific inhibitor of the ERK pathway (PD98059) recovered SPC-induced hypopigmentation. Moreover, we found that SPC s...

journal_title：Molecular and cellular biochemistry

authors： Jeong HS,Park KC,Kim DS

更新日期：2012-08-01 00:00:00

abstract：:AcMNPV is the first baculovirus to be sequenced and is considered a model of baculovirus. ac154 is a later expression gene in AcMNPV genome and its function is unknown. In this study, we explored the function of Ac154 in AcMNPV infection process in host Sf9 cells. The results showed that Ac154 was distributed in both ...

journal_title：Molecular and cellular biochemistry

authors： Bai H,Liang A,Fu Y

更新日期：2020-01-01 00:00:00

abstract：:By qualitative and quantitative PCR, we evaluated the expression of three messengers coding for SAT-1, SAT-2 and GalNAcT-1 in human samples of intestinal cancer and some cell lines (breast cancer and melanomas). Qualitative PCR demonstrated, in human tissues but not in the cell lines examined, the presence of an mRNA ...

journal_title：Molecular and cellular biochemistry

authors： Gornati R,Chini V,Rimoldi S,Meregalli M,Schiaffino E,Bernardini G

更新日期：2007-04-01 00:00:00

abstract：:It has been reported that mitochondria-independent or mitochondria-dependent (type I/II) Fas signaling pathways in leukemia cells depend on the amount of active caspase-8. However, Bid molecules, which could not be cleaved in type I cells, could be effectively cleaved by recombinant active caspase-8 in vitro. The clea...

journal_title：Molecular and cellular biochemistry

authors： Li Y,Qi L,Iwao A,Kihira K,Dida F,Song Z,Azuma E,Komada Y

更新日期：2009-11-01 00:00:00

abstract：:Genetic adaptation is one of the key features of Escherichia coli (E. coli) that ensure its survival in different hostile environments. E. coli seems to initiate biofilm development in response to specific environmental cues. A number of properties inherent within bacterial biofilms indicate that their gene expression...

journal_title：Molecular and cellular biochemistry

authors： Adnan M,Morton G,Hadi S

更新日期：2011-11-01 00:00:00

abstract：:Ischemic heart disease is the leading cause of death for both men and women worldwide, accruing 7.4 million deaths in 2012. There has been a continued search for better cardioprotective modalities that would reduce myocardial ischemia-reperfusion injury. Among these attempts, a more convenient model of ischemic precon...

journal_title：Molecular and cellular biochemistry

authors： Gill R,Kuriakose R,Gertz ZM,Salloum FN,Xi L,Kukreja RC

更新日期：2015-04-01 00:00:00

abstract：:The recombinant eukaryotic expression vector pCMV4-rmCGbeta, inserted full-length cDNA of the beta-subunit of rhesus monkey chorionic gonadotropin (rmCGbeta), as DNA immuno-contraceptive against CGbeta glycoprotein, has previously demonstrated the biological expression of rmCGbeta in vitro and in vivo. The plasmid DNA...

journal_title：Molecular and cellular biochemistry

authors： Chen Y,Liu Z,Yang Y,Chen YZ,Peng JP

更新日期：2002-02-01 00:00:00

abstract：:Exploring the function of interleukin (IL) 17 and related cytokine interactions have been proven useful toward understanding the role of inflammation in autoimmune diseases. Production of the inflammatory cytokine IL-23 by dendritic cells (DC's) has been shown to promote IL-17 expression by Th17 cells. It is well esta...

journal_title：Molecular and cellular biochemistry

authors： Salimi Elizei S,Poormasjedi-Meibod MS,Wang X,Kheirandish M,Ghahary A

更新日期：2017-07-01 00:00:00

abstract：:This paper investigated the effects of ox-LDL on PCSK9, and the molecular mechanisms of PCSK9 siRNA-inhibited apoptosis induced by ox-LDL in human umbilical vein endothelial cells (HUVECs), to clarify the role of PCSK9 in atherosclerogenesis. HUVECs were incubated with ox-LDL for 24 h. The apoptosis was observed by Ho...

journal_title：Molecular and cellular biochemistry

authors： Wu CY,Tang ZH,Jiang L,Li XF,Jiang ZS,Liu LS

更新日期：2012-01-01 00:00:00

abstract：:Circulating lipid peroxide, antioxidant components and the activities of defense enzymes were estimated in uterine cervical carcinoma patients (before and after radiotherapy and radiotherapy combined chemotherapy) and compared with controls. Some of the antioxidant components such as glutathione, vitamin E and seleniu...

journal_title：Molecular and cellular biochemistry

authors： Bhuvarahamurthy V,Balasubramanian N,Govindasamy S

更新日期：1996-05-10 00:00:00

abstract：:Three antisera were prepared against non-histone protein classes named NHCP1, NHCP2 and dehistonized chromatin (with different affinity to DNA) from hamster liver. Two main antigenic bands of MW 17,000 and 36,000 were specific in the NHCP1 fraction and one antigen of MW 56,000 was specific for the NHCP2 fraction from ...

journal_title：Molecular and cellular biochemistry

authors： Wojtkowiak Z,Kiliańska Z,Kłyszejko-Stefanowicz L

更新日期：1990-01-18 00:00:00

abstract：:This study aimed to explore the potential contribution of myofibrils to contractile dysfunction in Ca2+-paradox hearts. Isolated rat hearts were perfused with Krebs-Henseleit solution (Control), followed by Ca2+-depletion, and then Ca2+-repletion after Ca2+-depletion (Ca2+-paradox) by Langendorff method. During heart ...

journal_title：Molecular and cellular biochemistry

authors： Kovács Á,Kalász J,Pásztor ET,Tóth A,Papp Z,Dhalla NS,Barta J

更新日期：2017-06-01 00:00:00

abstract：:The OCT4 transcription factor is a crucial stem cells marker and it has been related to the cancer stem cells concept. Moreover, it has also been associated to the multiple drug resistance (MDR) phenotype. Our first results pointed out a straight relation between OCT4 and ABC transporters in K562-derivative MDR (Lucen...

journal_title：Molecular and cellular biochemistry

authors： Oliveira BR,Figueiredo MA,Trindade GS,Marins LF

更新日期：2015-02-01 00:00:00

abstract：:Our study evaluated the relationship between the endogenous production of prostacyclin and the antiarrhythmic effect of ischemic preconditioning against ischemic and reperfusion-induced tachyarrhythmia. Langendorff perfused rat hearts underwent 30 min regional ischemia with reperfusion. Preconditioning was induced by ...

journal_title：Molecular and cellular biochemistry

authors： Arad M,Oxman T,Leor R,Rabinowitz B

更新日期：1996-07-01 00:00:00

abstract：:Cardiac failure is one of the leading causes of mortality in developed countries. As life expectancies of the populations of these countries grow, the number of patients suffering from cardiac insufficiency also increases. Effective treatments are being sought and recently a new class of drugs, the calcium sensitisers...

journal_title：Molecular and cellular biochemistry

authors： Sorsa T,Pollesello P,Solaro RJ

更新日期：2004-11-01 00:00:00

abstract：:CYP3A5 is an important genetic contributor to inter-individual differences in CYP3A-dependent clinically important drugs of metabolism and also of various endogenous compounds and environmental contaminants. The CYP3A5*3 allele results in a truncated protein with loss of CYP3A5 expression and CYP3A5*6 is associated wi...

journal_title：Molecular and cellular biochemistry

authors： Bajpai P,Tripathi AK,Agrawal D

更新日期：2010-03-01 00:00:00

abstract：:The ubiquitin specific peptidase 22 (USP22) is a positive regulator of the growth of tumors. However, little is known about the impact of USP22 knockdown on the growth of human bladder cells. In the present study, we designed a series of asymmetric interfering RNAs (aiRNAs) and compared the efficacy of aiRNA and conve...

journal_title：Molecular and cellular biochemistry

authors： Lv L,Xiao XY,Gu ZH,Zeng FQ,Huang LQ,Jiang GS

更新日期：2011-01-01 00:00:00

abstract：:Thrombocytopenia is a major hematological concern in oxidative stress-associated pathologies and chronic clinical disorders, where premature platelet destruction severely affects the normal functioning of thrombosis and hemostasis. In addition, frequent exposure of platelets to chemical entities and therapeutic drugs ...

journal_title：Molecular and cellular biochemistry

authors： Jagadish S,Rajeev N,NaveenKumar SK,Sharath Kumar KS,Paul M,Hegde M,Basappa,Sadashiva MP,Girish KS,Rangappa KS

更新日期：2016-03-01 00:00:00

abstract：:The native form of phospholamban is not known and it is presently under debate whether this protein exists as a monomer or an oligomer in cardiac sarcoplasmic reticulum. The currently accepted model for phospholamban is pentameric, based primarily on its behavior in SDS-polyacrylamide gel electrophoresis. In this stud...

journal_title：Molecular and cellular biochemistry

authors： Harrer JM,Kranias EG

更新日期：1994-11-23 00:00:00

abstract：:Atherosclerosis is the leading cause of death in North America. It is characterized by thickening of the coronary artery wall by the formation of plaques, resulting in reduced blood flow. Plaque rupture and the consequent thrombosis may lead to sudden blockage of arteries and causing stroke and heart attack. In the la...

journal_title：Molecular and cellular biochemistry

authors： Choy PC,Mymin D,Zhu Q,Dakshinamurti K,O K

更新日期：2000-04-01 00:00:00

abstract：:Red blood cells (RBCs) enzymatically produce nitric oxide (NO) by a functional RBC-nitric oxide synthase (RBC-NOS). NO is a vascular key regulatory molecule. In RBCs its generation is complex and influenced by several factors, including insulin, acetylcholine, and calcium. NO availability is reduced in end-stage renal...

journal_title：Molecular and cellular biochemistry

authors： Di Pietro N,Giardinelli A,Sirolli V,Riganti C,Di Tomo P,Gazzano E,Di Silvestre S,Panknin C,Cortese-Krott MM,Csonka C,Kelm M,Ferdinandy P,Bonomini M,Pandolfi A

更新日期：2016-06-01 00:00:00

abstract：:The effects of Mg2+ concentration (Mg2+o, 0, 1.2, 2.4, and 4.8 mM) on the incidence of reperfusion arrhythmias and on the cellular electrical activity were studied in spontaneously beating rat hearts. The surface electrogram and the membrane potential were recorded in control conditions, during 10 min of regional isch...

journal_title：Molecular and cellular biochemistry

authors： Ponce Zumino A,Risler NR,Schanne OF,Ruiz Petrich E,Carrión A

更新日期：1997-06-01 00:00:00

abstract：:Amida was first isolated from a rat hippocampal cDNA library as an Arc-associated protein. Although previous studies have shown that Amida mRNA is predominantly expressed and developmentally regulated in rat testis and overexpression induces apoptosis, the function of Amida remains unclear. In this study, we found tha...

journal_title：Molecular and cellular biochemistry

authors： Gan Y,Taira E,Irie Y,Fujimoto T,Miki N

更新日期：2003-04-01 00:00:00

abstract：:Homogenates and plasma membranes were isolated from the livers of male Fischer 344 rats ranging in age from 19 hr to 92 days postnatal. These plasma membranes exhibited comparable levels of purity: protein yields were 2-2.5%; relative specific activities of 5'-nucleotidase and ouabain-sensitive Na+/K(+)-ATPase were fr...

journal_title：Molecular and cellular biochemistry

authors： Sulakhe-Hemmings SJ,Pulga VB,Tran ST

更新日期：1992-09-22 00:00:00

abstract：:Cardiac hypertrophy is an independent risk factor in the development of heart failure. However, the cellular mechanisms underlying the transition from compensated hypertrophy to heart failure are incompletely understood. The aim of this study was to investigate changes in myocardial substrate utilisation and function ...

journal_title：Molecular and cellular biochemistry

authors： Akki A,Smith K,Seymour AM

更新日期：2008-04-01 00:00:00

abstract：:Well-documented evidence suggests that environmental and occupational exposure of toxic metals or metal-containing compounds can cause a number of human diseases, including inflammation and cancer, through DNA damage, protein modifications, or lipid peroxidation. This mini-review addresses the mechanisms of cell death...

journal_title：Molecular and cellular biochemistry

authors： Chen F,Vallyathan V,Castranova V,Shi X

更新日期：2001-06-01 00:00:00

abstract：:Recent studies suggest JAK2 signaling may be a therapeutic target for treatment of gastric cancer (GC). However, the exact roles of JAK2 in gastric carcinogenesis are not very clear. Here, we have targeted JAK2 to be silenced by shRNA and investigated the biological functions and related mechanisms of JAK2 in GC cell ...

journal_title：Molecular and cellular biochemistry

authors： Qian C,Yao J,Wang J,Wang L,Xue M,Zhou T,Liu W,Si J

更新日期：2014-02-01 00:00:00

abstract：:The article "JIP3 localises to exocytic vesicles and focal adhesions in the growth cones of differentiated PC12 cells", written by "Patrick T. Caswell, Martin Dickens", was originally published electronically on the publisher's internet portal https://link.springer.com/article/10.1007/s11010-017-3222-7 on 20 November ...

journal_title：Molecular and cellular biochemistry

authors： Caswell PT,Dickens M

更新日期：2018-07-01 00:00:00

abstract：:The effects of different dietary fats on peritoneal macrophage plasma membrane fluidity, intracellular cyclic AMP (cAMP) production, GTP hydrolysis and TNF binding and TNF-induced IL1 and IL6 production was investigated. After a four week period, fluidity, as determined by both fluorescence recovery after photobleachi...

journal_title：Molecular and cellular biochemistry

authors： Tappia PS,Ladha S,Clark DC,Grimble RF

更新日期：1997-01-01 00:00:00