Hamster liver chromatin immunospecific non-histone proteins.

abstract：:Striatal neuronal cell death is one of the pathological features of Huntington's disease (HD). Overexpression of some heat shock proteins (HSPs) has been reported to suppress the aggregate formation of mutant huntingtin and concurrent cell death. Heat shock transcription factor-1 (HSF 1), a major transcription factor ...

journal_title：Molecular and cellular biochemistry

authors： Choi YJ,Om JY,Kim NH,Chang JE,Park JH,Kim JY,Lee HJ,Kim SS,Chun W

更新日期：2013-03-01 00:00:00

abstract：:Limited proteolysis of rabbit muscle phosphorylase kinase catalyzed by chymotrypsin generates a 33 kD product whose kinase activity is independent of both calcium and pH over the range of 6.8 to 8.3 (Malencik, D.A. & Fischer, E.H. Calcium and Cell Function III: 161-188, 1982). This active preparation consists of three...

journal_title：Molecular and cellular biochemistry

authors： Malencik DA,Zhao Z,Anderson SR

更新日期：1993-11-01 00:00:00

abstract：:Migration and invasion are important characteristics of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs), which are involved in joint damage and contribute to rheumatoid arthritis (RA) pathology. However, the underlying mechanisms remain unclear. Because epithelial-mesenchymal transition (EMT) is a key mech...

journal_title：Molecular and cellular biochemistry

authors： Zhu D,Zhao J,Lou A,Huang Q,OuYang Q,Zhu J,Fan M,He Y,Ren H,Yang M

更新日期：2019-09-01 00:00:00

abstract：:The natriuretic peptide receptor-A (NPR-A) is involved in blood pressure and body fluid regulation in order to help maintain cardiovascular homeostasis. It has been shown that these biological effects are mediated through the natriuretic peptide family of hormones, which bind NPR-A according to the rank order ANP>BNP>...

journal_title：Molecular and cellular biochemistry

authors： Marquis M,Fenrick R,Pedro L,Bouvier M,De Léan A

更新日期：1999-04-01 00:00:00

abstract：:Cytochrome c oxidase (COX), like other multi-subunit components of the respiratory chain, is controlled by both the nuclear and the mitochondrial genome. In order to find wether there is a close relationship between mRNAs encoded by the nucleus and by the mitochondrion, and between these mRNAs and enzyme activity, we ...

journal_title：Molecular and cellular biochemistry

authors： Gagnon J,Kurowski TT,Wiesner RJ,Zak R

更新日期：1991-09-18 00:00:00

abstract：:The development and growth of the prostate gland depends on androgen stimulation. Dihydrotestosterone (DHT) is the primary androgen responsible for prostate development and also for the pathogenesis of benign prostatic hyperplasia (BPH). The incidence of prostate cancer (PCa) and benign prostatic hypertrophy (BPH) con...

journal_title：Molecular and cellular biochemistry

authors： Torres JM,Gómez-Capilla JA,Ruiz E,Ortega E

更新日期：2003-08-01 00:00:00

abstract：:The present study is designed to investigate the effect of myocardial preconditioning with oxidative stress induced by pyrogallol or H2O2, on ischaemia-reperfusion induced myocardial injury. Isolated perfused rat heart was subjected to global ischaemia for 30 min followed by reperfusion for 120 min. Coronary effluent ...

journal_title：Molecular and cellular biochemistry

authors： Sharma A,Singh M

更新日期：2001-03-01 00:00:00

abstract：:Oxidants and inflammatory mediators such as tumour necrosis factor-alpha (TNF-alpha) activate nuclear factor kappa B (NF-kappaB) and activator protein-1 (AP-1) transcription factors, and enhance the expression of both pro-inflammatory and protective antioxidant genes. Remodelling of chromatin within the nucleus, contr...

journal_title：Molecular and cellular biochemistry

authors： Rahman I,Gilmour PS,Jimenez LA,MacNee W

更新日期：2002-05-01 00:00:00

abstract：:The pathophysiologic importance of insulin resistance in diseases such as obesity and diabetes mellitus has led to great interest in defining the mechanism of insulin action as well as the means to overcome the biochemical defects responsible for the resistance. Vanadium compounds have been discovered to mimic many of...

journal_title：Molecular and cellular biochemistry

authors： Fantus IG,Tsiani E

更新日期：1998-05-01 00:00:00

abstract：:Cryptotanshinone (CPT) is a natural compound extracted from herbal medicine that has been previously shown to possess antitumor properties in various types of human cancer cells. In the present study, we examined the potential role of CPT in the treatment of colorectal cancer. Using SW480, HCT116, and LOVO colorectal ...

journal_title：Molecular and cellular biochemistry

authors： Li W,Saud SM,Young MR,Colburn NH,Hua B

更新日期：2015-08-01 00:00:00

abstract：:The phosphorylation of rat cardiac microsomal proteins was investigated with special attention to the effects of okadaic acid (an inhibitor of protein phosphatases), inhibitor 2 of protein phosphatase 1 and inhibitor of cyclic AMP-dependent protein kinase (protein kinase A). The results showed that okadaic acid (5 mic...

journal_title：Molecular and cellular biochemistry

authors： Sulakhe PV,Vo XT,Morris TE,Pato MD,Khandelwal RL

更新日期：1997-10-01 00:00:00

abstract：:A number of acute and chronic neurodegenerative disorders are caused due to misfolding and aggregation of many intra- and extracellular proteins. Protein misfolding and aggregation processes in cells are strongly regulated by cellular molecular chaperones known as heat-shock proteins (Hsps) that include Hsp60, Hsp70, ...

journal_title：Molecular and cellular biochemistry

authors： Paul S,Mahanta S

更新日期：2014-01-01 00:00:00

abstract：:Airways inflammation, a pathological hallmark of asthma, is associated with the recruitment of pro-inflammatory and inflammatory cells like eosinophils, polymorphonuclear leucocytes cells, mononuclear cells, macrophages, epithelial desquamation, and airways remodeling with sub-epithelial fibrosis. Activated inflammato...

journal_title：Molecular and cellular biochemistry

authors： Khanduja KL,Kaushik G,Khanduja S,Pathak CM,Laldinpuii J,Behera D

更新日期：2011-01-01 00:00:00

abstract：:Chloroplasts from spinach can be separated into at least three different populations by countercurrent distribution using polymer two-phase systems. The chloroplast particles of the three populations differ in protein/chlorophyll ratio, ultrastructure and metabolism. One population, peak I, consists of intact chloropl...

journal_title：Molecular and cellular biochemistry

authors： Albertsson PA,Larsson C

更新日期：1976-06-15 00:00:00

abstract：:The levels of plasma apolipoprotein (apo) E, an anti-atherogenic protein involved in mammalian cholesterol transport, were found to be 2-3 fold lower in mice over-expressing human apoA-I gene. ApoE is mainly associated with VLDL and HDL-size particles, but in mice the majority of the apoE is associated with the HDL pa...

journal_title：Molecular and cellular biochemistry

authors： Srivastava RA

更新日期：2000-06-01 00:00:00

abstract：:Cytosolic purine nucleoside phosphorylase (PNPase) is a well known, and described enzyme which exists in a variety of organisms, both procaryotic and eucaryotic. More recently this enzyme was found in bovine liver mitochondria. The mitochondrial purine nucleoside phosphorylase was purified 63 fold and has a molecular ...

journal_title：Molecular and cellular biochemistry

authors： Haag R,Lewis RA

更新日期：1994-06-29 00:00:00

abstract：:Mitochondrial respiratory rates and regulation by phosphate acceptors were studied on permeabilized fiber bundles differing in their myosin heavy chain profiles. The acceptor control ratio, an indicator of oxidation to phosphorylation coupling, and mitochondrial K(m) for ADP were the highest in type I, intermediate in...

journal_title：Molecular and cellular biochemistry

authors： Gueguen N,Lefaucheur L,Fillaut M,Herpin P

更新日期：2005-08-01 00:00:00

abstract：:Progression of prostate cancer is facilitated by growth factors that activate critical signaling cascades thereby promote prostate cancer cell growth, survival, and migration. To investigate the effect of quercetin on insulin-like growth factor signaling and apoptosis in androgen independent prostate cancer cells (PC-...

journal_title：Molecular and cellular biochemistry

authors： Senthilkumar K,Elumalai P,Arunkumar R,Banudevi S,Gunadharini ND,Sharmila G,Selvakumar K,Arunakaran J

更新日期：2010-11-01 00:00:00

abstract：:Oxidized LDL is highly atherogenic as it stimulates macrophage cholesterol accumulation and foam cell formation, it is cytotoxic to cells of the arterial wall and it stimulates inflammatory and thrombotic processes. LDL oxidation can lead to its subsequent aggregation, which further increases cellular cholesterol accu...

journal_title：Molecular and cellular biochemistry

authors： Aviram M,Fuhrman B

更新日期：1998-11-01 00:00:00

abstract：:Telocytes (TCs) are a novel cell type identified among interstitial cells in various organs. TCs are characterized by very long cell processes (tens to hundreds micrometres) named telopodes (Tps) with uneven calibre: dilations (podoms) and very thin segments (podomers). However, little is known about the factors which...

journal_title：Molecular and cellular biochemistry

authors： Enciu AM,Popescu LM

更新日期：2015-12-01 00:00:00

abstract：:A multi-component solution, containing α-ketoglutaric acid (α-KG), 5-hydroxymethylfurfural (5-HMF), N-acetyl-seleno-L-methionine (NASeLM), and N-acetyl-L-methionine (NALM) as active ingredients, has been tested considering its supposed antioxidative effect with respect to heart transplantations. Oxidative stress was i...

journal_title：Molecular and cellular biochemistry

authors： Russ M,Jauk S,Wintersteiger R,Andrä M,Brcic I,Ortner A

更新日期：2019-11-01 00:00:00

abstract：:We investigated the spindle inhibitory properties of six arsenicals differing in their methylation or oxidation state. Human lymphoblasts were exposed for 6 h to either sodium arsenate (NaAs(V)), sodium arsenite (NaAs(III)), monomethylarsonic acid (MMA(V)), monomethylarsonous acid (MMA(III)), dimethylarsinic acid (DMA...

journal_title：Molecular and cellular biochemistry

authors： Kligerman AD,Doerr CL,Tennant AH

更新日期：2005-11-01 00:00:00

abstract：:The regulation patterns of gastric acid secretion in rats were investigated. Pentagastrin and histamine stimulate gastric acid secretion, but the inhibitors of DNA-dependent synthesis of RNA and of proteins prevent only the pentagastrin action. It has been found that pentagastrin induces histidine decarboxylase in gas...

journal_title：Molecular and cellular biochemistry

authors： Salganik RI,Bersimbaev RI,Argutinskaya SV,Kiseleva EV,Khristolyubova NB,Deribas VI

更新日期：1976-09-30 00:00:00

abstract：:L-arginine (L-Arg) uptake is mediated by members of cationic amino acid transporter (CAT) family and may coincide with the induction of nitric oxide synthases (NOS). The present study was conducted to investigate the extracellular concentrations of L-Arg regulating the CAT-1, CAT-4 and inducible NOS (iNOS) in chick in...

journal_title：Molecular and cellular biochemistry

authors： Yuan C,Zhang X,He Q,Li J,Lu J,Zou X

更新日期：2015-01-01 00:00:00

abstract：:To investigate the involvement of transforming growth factor-β1 (TGF-β1) and tissue inhibitor of metalloproteinase 4 (TIMP-4) in influencing the severity of atrial fibrosis in rheumatic heart disease (RHD) patients with atrial fibrillation (AF). The degree of myocardial fibrosis was evaluated using Masson staining. Th...

journal_title：Molecular and cellular biochemistry

authors： Sun Y,Huang ZY,Wang ZH,Li CP,Meng XL,Zhang YJ,Su F,Ma N

更新日期：2015-08-01 00:00:00

abstract：:Fasting is accompanied by a decrease in collagen biosynthesis. The mechanism of this phenomenon involves inhibition of prolidase activity, an enzyme that plays a key role in upregulation of collagen metabolism. The mechanism of fasting-induced inhibition of prolidase activity is not known. Phosphoenolpyruvate (PEP) is...

journal_title：Molecular and cellular biochemistry

authors： Cechowska-Pasko M,Palka J,Bańkowski E

更新日期：2004-10-01 00:00:00

abstract：:Maitake mushroom has been reported to favorably influence hypertension and diabetes mellitus. The purpose of this study was to compare the effects of whole Maitake mushroom powder and two extracts designated as ether soluble (ES) and water soluble (WS) on Zucker fatty rats (ZFR), a model of insulin resistance, and on ...

journal_title：Molecular and cellular biochemistry

authors： Talpur NA,Echard BW,Fan AY,Jaffari O,Bagchi D,Preuss HG

更新日期：2002-08-01 00:00:00

abstract：:The aim of the research was to study the role played by extracellular O2-radicals, which are implicated in cardiac cell damage and the protective effect by cell-permeable, nitroxide, superoxide dismutase-mimics. Cardiomyocytes cultures from 1-day-old rats served as the test-system. Experiments were performed since 5th...

journal_title：Molecular and cellular biochemistry

authors： Mohsen M,Pinson A,Zhang R,Samuni A

更新日期：1995-04-26 00:00:00

abstract：:Dual-specificity phosphatases (DSPs), which dephosphorylate proteins at Ser/Thr as well as Tyr residues, are thought to be involved in critical signaling events such as control of MAP kinases (MAPKs). We have isolated the cDNA for a novel DSP and termed it low molecular mass DSP-4 (LDP-4). LDP-4 is composed of 211 ami...

journal_title：Molecular and cellular biochemistry

authors： Takagaki K,Shima H,Tanuma N,Nomura M,Satoh T,Watanabe M,Kikuchi K

更新日期：2007-02-01 00:00:00

abstract：:The effect of increased serum levels of thyroid hormone (triiodothyronine, T3) on young rat testis spermatogenesis was studied by analysing molecular and morphological parameters. Hyperthyroidism was induced by either T3-treatment or 2- and 10-day cold exposure. The poly(ADP-ribosyl)ation of proteins catalysed by poly...

journal_title：Molecular and cellular biochemistry

authors： Faraone-Mennella MR,Ferone A,Marino L,Cardone A,Comitato R,Venditti P,Di Meo S,Farina B

更新日期：2009-03-01 00:00:00