Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains.

abstract：:A quarter of the human population with European background carries at least one allele of the OPRD1 gene that encodes the delta opioid receptor with cysteine at the amino acid position 27 (hδOR(Cys27)) instead of the evolutionary conserved phenylalanine (hδOR(Phe27)). The two variants have indistinguishable pharmacolo...

journal_title：Molecular and cellular biochemistry

authors： Tuusa JT,Petäjä-Repo UE

更新日期：2011-05-01 00:00:00

abstract：:The insoluble inclusion bodies of soluble leukemia inhibitory factor receptor fusion protein (gp 190 sol DAF) was solubilized in 8 M urea on the unfolding transitions, and several factors on the aggregate formation were indirectly analyzed for the refolding of gp 190 sol DAF. Results indicate that the refolding yield ...

journal_title：Molecular and cellular biochemistry

authors： Liu H,Moreau JF,Gualde N,Fu J

更新日期：1997-04-01 00:00:00

abstract：:One of the atrial natriuretic factor (ANF) receptors is a 180 kDa protein (180 kDa mGC) which possesses the extraordinary characteristic of being bifunctional: it is both a receptor and a guanylate cyclase. In addition to the 180 kDa mGC, there exists another 120-130 kDa protein which is also bifunctional and a 120 kD...

journal_title：Molecular and cellular biochemistry

authors： Marala RB,Sharma RK

更新日期：1992-01-15 00:00:00

abstract：:The effect of increased serum levels of thyroid hormone (triiodothyronine, T3) on young rat testis spermatogenesis was studied by analysing molecular and morphological parameters. Hyperthyroidism was induced by either T3-treatment or 2- and 10-day cold exposure. The poly(ADP-ribosyl)ation of proteins catalysed by poly...

journal_title：Molecular and cellular biochemistry

authors： Faraone-Mennella MR,Ferone A,Marino L,Cardone A,Comitato R,Venditti P,Di Meo S,Farina B

更新日期：2009-03-01 00:00:00

abstract：:The presence of a butyrylcholinesterase (BuChE, EC 3.1.1.8) in the musocal cells of the chicken intestine was demonstrated by histochemical and biochemical methods. The study of its distribution, along the intestine from duodenum to rectum, showed that the jejuno-ileum possesses the highest activity. Sucrose gradient ...

journal_title：Molecular and cellular biochemistry

authors： Sine JP,Ferrand R,Colas B

更新日期：1989-01-23 00:00:00

abstract：:The results of our previous studies demonstrated that acute streptozotocin-induced diabetes in rats evoked a decrease in skin collagen content with little effect on glycosaminoglycans (GAG) content. In our present study we employed the model of chronic diabetes in order to check its effect on skin GAG content. It was ...

journal_title：Molecular and cellular biochemistry

authors： Cechowska-Pasko M,Pałka J,Bańkowski E

更新日期：1996-01-12 00:00:00

abstract：:Proteoglycans carrying chondroitin sulfate side chains have been shown to fulfill important biological functions in development, disease, and signaling. One area of considerable interest is the functional importance of chondroitin sulfates as inhibitors of the regeneration of axonal projections in the mammalian centra...

journal_title：Molecular and cellular biochemistry

authors： Klüppel M

更新日期：2011-05-01 00:00:00

abstract：:Ovarian cancer is one of the greatest causes of cancer death in women. The association of TMEM49 and ovarian cancer is poorly defined. Here, we reported that TMEM49 was significantly increased in ovarian tumor tissues compared to ovarian normal tissues. Furthermore, down-regulation of TMEM49 through RNA interference i...

journal_title：Molecular and cellular biochemistry

authors： Zheng L,Chen L,Zhang X,Zhan J,Chen J

更新日期：2016-05-01 00:00:00

abstract：:Hypertension and related oxidative stress are involved in the pathogenesis of any renal diseases. Angiotensin-converting enzyme inhibitors have multi-directional renoprotective effects. In this study, we aimed to investigate whether lisinopril treatment has any biochemical alterations on renal tissue in L-NAME (Nε-nit...

journal_title：Molecular and cellular biochemistry

authors： Oktem F,Kirbas A,Armagan A,Kuybulu AE,Yilmaz HR,Ozguner F,Uz E

更新日期：2011-06-01 00:00:00

abstract：:The aim of the research was to study the role played by extracellular O2-radicals, which are implicated in cardiac cell damage and the protective effect by cell-permeable, nitroxide, superoxide dismutase-mimics. Cardiomyocytes cultures from 1-day-old rats served as the test-system. Experiments were performed since 5th...

journal_title：Molecular and cellular biochemistry

authors： Mohsen M,Pinson A,Zhang R,Samuni A

更新日期：1995-04-26 00:00:00

abstract：:Guanidino compounds of guanidinoethanesulfonic acid, guanidinoacetic acid, guanidinosuccinic acid, N-acetylarginine, beta-guanidinopropionic acid, creatinine, gamma-guanidinobutyric acid, arginine, guanidine, methylguanidine, homoarginine and alpha-guanidinoglutaric acid are present in the mammalian brain. These guani...

journal_title：Molecular and cellular biochemistry

authors： Hiramatsu M

更新日期：2003-02-01 00:00:00

abstract：:Studies have established that major increases in muscarinic acetylcholine receptor (mAchR) binding in the brain appear to coincide with synaptogenesis. The neuroblastoma x glioma hybrid NG108-15 cell line has been demonstrated to possess numerous functional characteristics of intact neurons, including synapse formatio...

journal_title：Molecular and cellular biochemistry

authors： Ghahary A,Cheng KW

更新日期：1989-04-11 00:00:00

abstract：:Inhalation of silica in a number of occupational settings can result in debilitating and costly lung disease. It is thought that the pathological replacement of functional lung tissue with fibrotic lesions in silica-induced lung disease is the result of chronic inflammation mediated by products of the silica-exposed a...

journal_title：Molecular and cellular biochemistry

authors： Chen F,Shi X

更新日期：2002-05-01 00:00:00

abstract：:A membrane-bound L-asparaginase (EC 3.5.1.1) of Tetrahymena pyriformis was purified to homogeneity. The purified enzyme is a lipoprotein, since it is inactivated by phospholipase C and its activity is restored by the addition of naturally occurring lipids, such as phosphatidylcholine, triolein and oleyl acetate. The r...

journal_title：Molecular and cellular biochemistry

authors： Tsirka SA,Kyriakidis DA

更新日期：1988-10-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are two hormones produced and secreted by the heart to control blood pressure, body fluid homeostasis and electrolyte balance. Each peptide binds to a common family of 3 receptors (GC-A, GC-B and C-receptor) with varying degrees of affinity. The pro...

journal_title：Molecular and cellular biochemistry

authors： Tse MY,Watson JD,Sarda IR,Flynn TG,Pang SC

更新日期：2001-03-01 00:00:00

abstract：:Though, it is quite well-known how retinoic acid (RA) is able to induce neuritogenesis in different in vitro models, the putative role exerted by reactive oxygen species (ROS) during this process still need to be further studied. For such purpose, we used a neuronal-like cell line (SH-SY5Y cells) in order to investiga...

journal_title：Molecular and cellular biochemistry

authors： da Frota Junior ML,Pires AS,Zeidán-Chuliá F,Bristot IJ,Lopes FM,de Bittencourt Pasquali MA,Zanotto-Filho A,Behr GA,Klamt F,Gelain DP,Moreira JC

更新日期：2011-12-01 00:00:00

abstract：:Circadian rhythms help organisms adapt to changes of external environment by regulating energy metabolism and remaining the balance of homeostasis. Numerous researches have proved that the physiological function of liver was precisely controlled by circadian rhythms. Clock, one of core circadian genes, has been demons...

journal_title：Molecular and cellular biochemistry

authors： Yang S,Liu Y,Guo Y,Liu R,Qi F,Li X,Yu H,Cheng S,Wang Z

更新日期：2020-04-01 00:00:00

abstract：:A literature search has been conducted to see to what extent steady-state kinetics studies in the period 1965-1976 have revealed deviations from Michaelis-Menten kinetics. It was found that over 800 enzymes have been reported as giving complex curves for a variety of reasons and a group by group classification of all ...

journal_title：Molecular and cellular biochemistry

authors： Hill CM,Waight RD,Bardsley WG

更新日期：1977-05-03 00:00:00

abstract：:Spray-dried milk enriched with n-3 fatty acids from linseed oil or fish oil were fed to rats to study its influence on liver lipid peroxides, hepatic antioxidant enzyme activities, serum prostaglandins and platelet aggregation. Significant level of alpha linolenic acid, eicosapentaenoic acid and docosahexaenoic acid w...

journal_title：Molecular and cellular biochemistry

authors： Ramaprasad TR,Baskaran V,Krishnakantha TP,Lokesh BR

更新日期：2005-12-01 00:00:00

abstract：:Ventricular electrical conduction has been investigated in the streptozotocin (STZ)-induced diabetic rat. Diabetes was induced with a single injection of STZ (60 mg/kg bodyweight, ip). The ECG was measured continuously, in vivo, using a biotelemetry system. Left ventricular action potentials were recorded with an extr...

journal_title：Molecular and cellular biochemistry

authors： Howarth FC,Jacobson M,Qureshi MA,Shafiullah M,Hameed RS,Zilahi E,Al Haj A,Nowotny N,Adeghate E

更新日期：2009-08-01 00:00:00

abstract：:In the context of high human consumption of fructose diets, there is an imperative need to understand how dietary fructose intake influence cellular and molecular mechanisms and thereby affect β-cell dysfunction and insulin resistance. While evidence exists for a relationship between high-fat-induced insulin resistanc...

journal_title：Molecular and cellular biochemistry

authors： Balakumar M,Raji L,Prabhu D,Sathishkumar C,Prabu P,Mohan V,Balasubramanyam M

更新日期：2016-12-01 00:00:00

abstract：:The renin-angiotensin (RAS) pathway has an important role in the etiology of heart failure and given the importance of RAS as a therapeutic target in various cardiomyopathies, genetic polymorphisms in the RAS genes may modulate the risk and severity of disease in cardiomyopathy patients. In the present study, we exami...

journal_title：Molecular and cellular biochemistry

authors： Rani B,Kumar A,Bahl A,Sharma R,Prasad R,Khullar M

更新日期：2017-03-01 00:00:00

abstract：:Whether the response of the fetal heart to ischemia-reperfusion is associated with activation of the c-Jun N-terminal kinase (JNK) pathway is not known. In contrast, involvement of the sarcolemmal L-type Ca2+ channel (LCC) and the mitochondrial KATP (mitoKATP) channel has been established. This work aimed at investiga...

journal_title：Molecular and cellular biochemistry

authors： Sarre A,Gardier S,Maurer F,Bonny C,Raddatz E

更新日期：2008-06-01 00:00:00

abstract：:Beta-1,4-galactosyltransferase 1 (beta1,4-GT 1) is the key enzyme transferring galactose to the terminal N-acetylglucosamine (GlcNAc) forming Galbeta3-->4GlcNAc structure in the Golgi apparatus. In addition, it also serves as a cell adhesion molecule by recognizing and binding to terminal GlcNAc of glycoconjugates on ...

journal_title：Molecular and cellular biochemistry

authors： Zhang SW,Xu SL,Cai MM,Yan J,Zhu XY,Hu Y,Gu JX

更新日期：2001-05-01 00:00:00

abstract：:Guanidinosuccinic acid is an aberrant metabolite isolated 40 years ago in the blood and urine of uremic subjects and a suspect in the toxicity associated with renal failure. It plays a minor role in the bleeding diathesis of uremia, contributes to the methyl group deficiency of dialysis patients, and is a factor in th...

journal_title：Molecular and cellular biochemistry

authors： Cohen BD

更新日期：2007-04-01 00:00:00

abstract：:Caveolin-1 (Cav-1) expression frequently found in lung cancer was linked with disease prognosis and progression. This study reveals for the first time that Cav-1 sensitizes cisplatin-induced lung carcinoma cell death by the mechanism involving oxidative stress modulation. We established stable Cav-1 overexpressed (H46...

journal_title：Molecular and cellular biochemistry

authors： Pongjit K,Chanvorachote P

更新日期：2011-12-01 00:00:00

abstract：:The effect of beta-alanyl-L-histidinato zinc (AHZ) on protein components in osteoblastic MC3T3-E1 cells was investigated. Cells were cultured for 3 days at 37 degrees C in CO2 incubator in plastic dishes containing alpha-modified minimum essential medium supplemented with 10% fetal bovine serum. After the cultures, th...

journal_title：Molecular and cellular biochemistry

authors： Yamaguchi M,Hashizume M

更新日期：1994-07-27 00:00:00

abstract：:Hypoxia impairs the muscle fibre-type shift from fast-to-slow during post-natal development; however, this adaptation could be a consequence of the reduced voluntary physical activity associated with hypoxia exposure rather than the result of hypoxia per se. Moreover, muscle oxidative capacity could be reduced in hypo...

journal_title：Molecular and cellular biochemistry

authors： Chaillou T,Koulmann N,Meunier A,Chapot R,Serrurier B,Beaudry M,Bigard X

更新日期：2014-05-01 00:00:00

abstract：:Members of the family of intracellular lipid binding proteins (iLBPs) have been implicated in cytoplasmic transport of lipophilic ligands, such as long-chain fatty acids and retinoids. iLBPs are low molecular mass proteins (14-16 kDa) sharing a common structural fold. The iLBP family likely arose through duplication a...

journal_title：Molecular and cellular biochemistry

authors： Schaap FG,van der Vusse GJ,Glatz JF

更新日期：2002-10-01 00:00:00

abstract：:The identification of informative biomarkers that could predict the treatment response is particularly important in the triple-negative (TN) breast cancer, which is characterized by biological diversity. The aim of this study was to investigate the impact of vascular endothelial growth factor receptor (VEGFR2) express...

journal_title：Molecular and cellular biochemistry

authors： Babyshkina N,Zavyalova M,Tarabanovskaya N,Dronova T,Krakhmal N,Slonimskaya E,Kzhyshkowska J,Choynzonov E,Cherdyntseva N

更新日期：2018-07-01 00:00:00