Science for managing ecosystem services: Beyond the Millennium Ecosystem Assessment.

abstract：:Spumaviruses, commonly called foamy viruses (FV), are complex retroviruses that establish lifelong persistent infections without any accompanying pathologies. In tissue culture, cells can be either lytically or latently infected, depending on cell type. Regulation of FV replication is controlled by two promoters: the ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Meiering CD,Linial ML

更新日期：2002-11-12 00:00:00

abstract：:KRAS interacts with the inner leaflet of the plasma membrane (PM) using a hybrid anchor that comprises a lysine-rich polybasic domain (PBD) and a C-terminal farnesyl chain. Electrostatic interactions have been envisaged as the primary determinant of interactions between KRAS and membranes. Here, we integrated molecula...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zhou Y,Prakash PS,Liang H,Gorfe AA,Hancock JF

更新日期：2021-02-09 00:00:00

abstract：:The three-dimensional structures of the inactive protein precursors (zymogens) of the serine, cysteine, aspartic, and metalloprotease classes of proteolytic enzymes are known. Comparisons of these structures with those of the mature, active proteases reveal that, in general, the preformed, active conformations of the ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Khan AR,Khazanovich-Bernstein N,Bergmann EM,James MN

更新日期：1999-09-28 00:00:00

abstract：:Fungi play crucial roles in the biogeochemistry of terrestrial ecosystems, most notably as saprophytes decomposing organic matter and as mycorrhizal fungi enhancing plant nutrient uptake. However, a recurrent problem in fungal ecology is to establish the trophic status of species in the field. Our interpretations and ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Högberg P,Plamboeck AH,Taylor AF,Fransson PM

更新日期：1999-07-20 00:00:00

abstract：:Protein S (ProS) and growth arrest-specific 6 (Gas6) bind to phosphatidylserine (PtdSer) and induce efferocytosis upon binding TAM-family receptors (Tyro3, Axl, and Mer). Here, we produced mouse ProS, Gas6, and TAM-receptor extracellular region fused to IgG fragment crystallizable region in HEK293T cells. ProS and Gas...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yanagihashi Y,Segawa K,Maeda R,Nabeshima YI,Nagata S

更新日期：2017-08-15 00:00:00

abstract：:The mutation spectrum induced by the widely used antitumor drug cis-diamminedichloroplatinum(II) (cis-DDP) showed that cisDDP[d(ApG)] adducts, although they account for only 25% of the lesions formed, are approximately 5 times more mutagenic than the major GG adduct. We report the construction of vectors bearing a sin...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Burnouf D,Gauthier C,Chottard JC,Fuchs RP

更新日期：1990-08-01 00:00:00

abstract：:The charge density distribution of a protein has been refined experimentally. Diffraction data for a crambin crystal were measured to ultra-high resolution (0.54 A) at low temperature by using short-wavelength synchrotron radiation. The crystal structure was refined with a model for charged, nonspherical, multipolar a...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Jelsch C,Teeter MM,Lamzin V,Pichon-Pesme V,Blessing RH,Lecomte C

更新日期：2000-03-28 00:00:00

abstract：:Resistance to cobalt, zinc, and cadmium specified by the czc determinant on plasmid pMOL30 in Alcaligenes eutrophus results from a cation efflux system. Five membrane-bound polypeptides that were expressed in Escherichia coli from this determinant under the control of a phage T7 promoter were assigned to four open rea...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Nies DH,Nies A,Chu L,Silver S

更新日期：1989-10-01 00:00:00

abstract：:We show that bromoacetaldehyde, which reacts selectively at the N-1 and N-6 positions of unpaired adenine and at the N-3 and N-4 positions of unpaired cytosine residues reacts with chromosomal DNA in intact cells at probable regulatory sequences near active genes. A region of about 200 base pairs 5' to the chicken bet...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kohwi-Shigematsu T,Gelinas R,Weintraub H

更新日期：1983-07-01 00:00:00

abstract：:In this era of unprecedented biodiversity loss and increased zoonotic disease emergence, it is imperative to understand the effects of biodiversity on zoonotic pathogen dynamics in wildlife. Whether increasing biodiversity should lead to a decrease or increase in infection prevalence, termed the dilution and amplifica...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Luis AD,Kuenzi AJ,Mills JN

更新日期：2018-07-31 00:00:00

abstract：:Phosphatidylionsitol 4,5-bisphosphate (PIP(2)), a substrate of phospholipase C, has recently been recognized to regulate membrane-associated proteins and act as a signal molecule in phospholipase C-linked Gq-coupled receptor (GqPCR) pathways. However, it is not known whether PIP(2) depletion induced by GqPCRs can act ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cho H,Lee D,Lee SH,Ho WK

更新日期：2005-03-22 00:00:00

abstract：:Liquid RNA.DNA hybridization with separated strands of adenovirus type 2 DNA revealed that late nuclear RNA can hybridize to about 85% of the 1-strand and 10-15% of the h-strand, whereas late cytoplasmic RNA hybridizes to 65-70% and 25% of the l- and h-strand, respectively. With separated strands from the six EcoRI fr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pettersson U,Philipson L

更新日期：1974-12-01 00:00:00

abstract：:In Trimenia moorei, an extant member of the ancient angiosperm clade Austrobaileyales, we found a remarkable pattern of female gametophyte (egg-producing structure) development that strikingly resembles that of pollen tubes and their intrasexual competition within the maternal pollen tube transmitting tissues of most ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bachelier JB,Friedman WE

更新日期：2011-07-26 00:00:00

abstract：:Erythroid Krüppel-like factor (EKLF), which binds to the CACCC box in the beta-globin promoter, is required for the expression of the beta-globin gene in adult erythroid cells. It was recently demonstrated that EKLF is also required for the activity of the beta-globin locus control region (LCR) 5'HS3. Some evidence su...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lee JS,Lee CH,Chung JH

更新日期：1999-08-31 00:00:00

abstract：:A "projection function," P(x,z), is defined as the partial integral of the molecular electron density, rho(x,y,z), over the region -infinity < y < +infinity. The projection provides a three-dimensional representation of molecular electron distributions. Chemically useful information can be discerned from graphical dis...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Streitwieser A,Collins JB,McKelvey JM,Grier D,Sender J,Toczko AG

更新日期：1979-06-01 00:00:00

abstract：:The transformation of human cells was examined by transfection of cloned oncogenic DNAs derived from the tumor virus simian virus 40 and from the human bladder carcinoma cell line EJ into diploid fibroblasts derived from foreskin (FS-2 cells). The simian virus 40 DNA was found to induce a morphologically transformed p...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sager R,Tanaka K,Lau CC,Ebina Y,Anisowicz A

更新日期：1983-12-01 00:00:00

abstract：:Nicotiana tabacum cv. Turkish Samsun NN plants were transformed with a modified and truncated replicase gene encoded by RNA-2 of cucumber mosaic virus strain Fny. The replicase gene had been modified by deleting a 94-base-pair region spanning nucleotides 1857-1950; the deletion also caused a shift in the open reading ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Anderson JM,Palukaitis P,Zaitlin M

更新日期：1992-09-15 00:00:00

abstract：:During cytokinesis, a cleavage furrow generated by actomyosin ring contraction is restructured into the midbody, a platform for the assembly of the abscission machinery that controls the final separation of daughter cells. The polymerization state of F-actin is important during assembly, ingression, disassembly, and c...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Terry SJ,Donà F,Osenberg P,Carlton JG,Eggert US

更新日期：2018-02-27 00:00:00

abstract：:The transcription of genes encoding gluconeogenic enzymes is tightly regulated during the perinatal period. These genes are induced by glucagon (cAMP) and glucocorticoids and repressed by insulin. To address the role of cAMP and glucocorticoids in the physiological activation of genes encoding gluconeogenic enzymes in...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Montoliu L,Blendy JA,Cole TJ,Schütz G

更新日期：1995-05-09 00:00:00

abstract：:Using single-cell sequence analysis, we discovered that a high proportion of cells in tissues as diverse as buccal epithelium and heart muscle contain high proportions of clonal mutant mtDNA expanded from single initial mutant mtDNA molecules. We demonstrate that intracellular clonal expansion of somatic point mutatio...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Nekhaeva E,Bodyak ND,Kraytsberg Y,McGrath SB,Van Orsouw NJ,Pluzhnikov A,Wei JY,Vijg J,Khrapko K

更新日期：2002-04-16 00:00:00

abstract：:Anti-TRAP (AT) is a small zinc-binding protein that regulates tryptophan biosynthesis in Bacillus subtilis by binding to tryptophan-bound trp RNA-binding attenuation protein (TRAP), thereby preventing it from binding RNA, and allowing transcription and translation of the trpEDCFBA operon. Crystallographic and sediment...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sachleben JR,McElroy CA,Gollnick P,Foster MP

更新日期：2010-08-31 00:00:00

abstract：:Epstein-Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV) cause ∼2% of all human cancers. RNase R-resistant RNA sequencing revealed that both gammaherpesviruses encode multiple, uniquely stable, circular RNAs (circRNA). EBV abundantly expressed both exon-only and exon-intron circRNAs from the BamHI A rightward ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Toptan T,Abere B,Nalesnik MA,Swerdlow SH,Ranganathan S,Lee N,Shair KH,Moore PS,Chang Y

更新日期：2018-09-11 00:00:00

abstract：:Improving global yields of important agricultural crops is a complex challenge. Enhancing yield and resource use by engineering improvements to photosynthetic carbon assimilation is one potential solution. During the last 40 million years C(4) photosynthesis has evolved multiple times, enabling plants to evade the cat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Whitney SM,Sharwood RE,Orr D,White SJ,Alonso H,Galmés J

更新日期：2011-08-30 00:00:00

abstract：:Energy-storing artificial-photosynthetic systems for CO2 reduction must derive the reducing equivalents from a renewable source rather than from sacrificial donors. To this end, a homogeneous, integrated chromophore/two-catalyst system is described that is thermodynamically capable of photochemically driving the energ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： La Porte NT,Moravec DB,Hopkins MD

更新日期：2014-07-08 00:00:00

abstract：:Using tunicamycin, we have investigated the role of glycoproteins in membrane transport. Tunicamycin is a glucosamine-containing antibiotic that specifically inhibits dolichol pyrophosphate-mediated glycosylation of asparaginyl residues of glycoproteins. Inhibition of protein glycosylation in chick embryo fibroblasts ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Olden K,Pratt RM,Jaworski C,Yamada KM

更新日期：1979-02-01 00:00:00

abstract：:In normal vision, shifts of attention are usually followed by saccadic eye movements. Neurons in extrastriate area V4 are modulated by focal attention when eye movements are withheld, but they also respond in advance of visually guided saccadic eye movements. We have examined the visual selectivity of saccade-related ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Moore T,Tolias AS,Schiller PH

更新日期：1998-07-21 00:00:00

abstract：:Fifty cats with feline leukemia virus (FeLV) infection and leukemia-lymphoma complex were treated by ex vivo immunoadsorption with Staphylococcus protein A-bound filters. Most cats responded to therapy. Twelve showed tumor regression, including disappearance of tumor cells, but died later of other complications. Three...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu WT,Engelman RW,Trang LQ,Hau K,Good RA,Day NK

更新日期：1984-06-01 00:00:00

abstract：:Staphylococcal protein A (SpA) is anchored to the cell wall envelope of Staphylococcus aureus by sortase A, which links the threonyl (T) of its C-terminal LPXTG motif to peptidoglycan cross-bridges (i.e., Gly5). SpA binds the Fcγ domains of IgG and protects staphylococci from opsonophagocytic clearance. Moreover, SpA ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Becker S,Frankel MB,Schneewind O,Missiakas D

更新日期：2014-01-28 00:00:00

abstract：:The concepts of source and quantum action principle are used to produce the phonon Green's function appropriate for an initial phonon vacuum state. An application to the Mossbauer effect is presented. ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schwinger J

更新日期：1991-08-01 00:00:00

abstract：:Monoamines, including dopamine (DA), have been linked to aggression in various species. However, the precise role or roles served by the amine in aggression have been difficult to define because dopaminergic systems influence many behaviors, and all can be altered by changing the function of dopaminergic neurons. In t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Alekseyenko OV,Chan YB,Li R,Kravitz EA

更新日期：2013-04-09 00:00:00