Methodology to improve epidermal barrier homeostasis: how to accelerate the barrier recovery?

Abstract:

:Good water-impermeable barrier function is vital for healthy skin. Abnormality of the barrier function is observed in a variety of skin diseases, such as atopic dermatitis, psoriasis and contact dermatitis. Moreover, repeated barrier disruption induces epidermal hyperplasia and inflammation. On the other hand, acceleration of the barrier recovery prevents epidermal hyperplasia induced by barrier disruption in a dry environment. Thus, methods to improve the barrier function are very important for clinical dermatology. Recently, we have been searching for new reagents and/or new materials to improve barrier homeostasis. In this review, I will describe our recent findings and show how they provide the basis for a new perspective for clinical dermatology.

journal_name

Int J Cosmet Sci

authors

Denda M

doi

10.1111/j.1468-2494.2008.00487.x

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

79-86

issue

2

eissn

0142-5463

issn

1468-2494

pii

ICS487

journal_volume

31

pub_type

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