Identification of B-cell epitopes of Bet v 1 involved in cross-reactivity with food allergens.

abstract：:IgG-binding to the surface of Langerhans cells (LC) is a feature of primary Sjögren's syndrome and might be associated with qualitative and quantitative defects in LC. Fifteen patients with primary Sjögren's syndrome and 15 healthy controls had a punch biopsy performed from clinically unaffected skin. LC were enumerat...

journal_title：Allergy

authors： Oxholm P,Oxholm A,Manthorpe R

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Children with spina bifida (SB) are exposed to latex soon after birth during bladder catheterization, rectal disimpaction, and multiple surgical procedures. IgE-mediated latex-allergic reactions have been reported recently in these children. Our study was designed to assess the prevalence of allergic reactio...

journal_title：Allergy

authors： Kattan H,Harfi HA,Tipirneni P

更新日期：1999-01-01 00:00:00

abstract：:We developed an antigen- and isotype-specific ELISA for the rapid detection of native serum immune complexes (IC). It is a sandwich assay, in which a solid phase antigen-specific capture antibody selectively binds the antigen-specific IC via the antigen. The isotype of the bound IC is then identified using an enzyme-l...

journal_title：Allergy

authors： Bell SJ,Potter PC

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:In a previous controlled study we demonstrated that preseasonal grass pollen immunotherapy for three years was effective in children. In the current study we examined the same group of patients to see if there is still a benefit six years after discontinuation of treatment. METHODS:Thirteen of 14 patients w...

journal_title：Allergy

authors： Eng PA,Reinhold M,Gnehm HP

更新日期：2002-04-01 00:00:00

abstract：:The possible dependence of the dual cutaneous reaction (DCR) on activation of the complement and coagulation systems was further elucidated. Heterologous whole anti-human IgE was injected intradermally (i.d.) on the volar aspect of the forearms of 17 drug-free healthy volunteers and venous samples for the selected lab...

journal_title：Allergy

authors： Grönneberg R

更新日期：1985-11-01 00:00:00

abstract：:A safe food supply is a legitimate expectation of consumers, which the food industry must meet. Allergic reactions to food are recognised as a significant public health problem. Protecting allergic consumers against such reactions, while minimising the impact of food allergy on their quality of life, poses a challenge...

journal_title：Allergy

authors： Crevel RW

更新日期：2001-01-01 00:00:00

abstract：:For almost 4 years, the stability of Der p I was assessed by RAST inhibition in house-dust samples incubated under simulated domestic conditions (5 or 25 degrees C and 75% relative humidity). Der p I concentrations were determined before heating dust samples at 60 degrees C to kill the mites, and at 0, 6, 14, 21, and ...

journal_title：Allergy

authors： Kort HS,Kniest FM

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Recent evidence indicates that Staphylococcus aureus, one of the most important human pathogens, secretes vesicles into the extracellular milieu. OBJECTIVE:To evaluate whether inhalation of S. aureus-derived extracellular vesicles (EV) is causally related to the pathogenesis of inflammatory pulmonary diseas...

journal_title：Allergy

authors： Kim MR,Hong SW,Choi EB,Lee WH,Kim YS,Jeon SG,Jang MH,Gho YS,Kim YK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:To date, there has been no reliable in vitro test to either diagnose or differentiate nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD). The aim of the present study was to develop and validate an artificial neural network (ANN) for the prediction of N-ERD in patients with a...

journal_title：Allergy

authors： Tyrak KE,Pajdzik K,Konduracka E,Ćmiel A,Jakieła B,Celejewska-Wójcik N,Trąd G,Kot A,Urbańska A,Zabiegło E,Kacorzyk R,Kupryś-Lipińska I,Oleś K,Kuna P,Sanak M,Mastalerz L

更新日期：2020-07-01 00:00:00

abstract：:The presence of indoor allergens in Finnish homes was studied for the first time. Dust samples (n = 30) were collected by vacuuming a 1 m2 area from a living-room carpet in 30 apartments divided into three groups: homes with cats (n = 10), homes with dogs (n = 10), and homes without pets (n = 10). The levels of major ...

journal_title：Allergy

authors： Raunio P,Pasanen AL,Reiman M,Virtanen T

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Involvement of paranasal sinuses has been suggested in allergic rhinitis but not clearly demonstrated. AIMS:To investigate the relationship between intermittent allergic rhinitis and computerized tomography (CT). METHODS:Twenty patients with intermittent rhinitis and sensitized to cypress pollens underwent...

journal_title：Allergy

authors： Piette V,Bousquet C,Kvedariene V,Dhivert-Donnadieu H,Crampette L,Senac JP,Bousquet J,Demoly P

更新日期：2004-08-01 00:00:00

abstract：:Twenty patients with severe or medium severe asthma were given atenolol (Atenol ICI-Pharma) and/or metoprolol (Seloken Hässle) for tachycardia, hyperkinetic tremor, arterial hypertension or symptoms of angina pectoris. These cardioselective beta-blocking drugs caused only a very slight decrease in PF values. There was...

journal_title：Allergy

authors： Carlson C,Järvinen KA

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Hen's egg (HE) allergy is a common disease in childhood. HE-specific serum IgE has been correlated with the outcome of oral food challenge tests, and diagnostic decision points have been described as helpful but still not sufficient to reduce the requirement for oral food challenges. The aim of the study was...

journal_title：Allergy

authors： Ahrens B,Lopes de Oliveira LC,Schulz G,Borres MP,Niggemann B,Wahn U,Beyer K

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Dissecting complex diseases in underlying distinct traits and studying these for their genetic basis might enhance the power as well as the specificity, of detection of disease genes. These phenotypes are known as intermediate phenotypes. OBJECTIVE:We were interested in the atopic basis of asthma, and used ...

journal_title：Allergy

authors： Kurz T,Altmueller J,Strauch K,Rüschendorf F,Heinzmann A,Moffatt MF,Cookson WO,Inacio F,Nürnberg P,Stassen HH,Deichmann KA

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:The mechanisms driving glucocorticoid (GC) insensitivity in patients with severe asthma are still unknown. Recent evidence suggests the existence of GC-insensitive pathways in airway smooth muscle (ASM) caused by a defect in GC receptor (GRα) function. We examined whether other mechanisms could potentially e...

journal_title：Allergy

authors： Chachi L,Abbasian M,Gavrila A,Alzahrani A,Tliba O,Bradding P,Wardlaw AJ,Brightling C,Amrani Y

更新日期：2017-01-01 00:00:00

abstract：:A common feature of environmental irritants is their ability to cause local inflammation which could alter airway function. The principal targets of such injury are the epithelial cells lining the airway passages and the lower respiratory gas-exchange areas. While host atopy is a recognized risk factor for airway infl...

journal_title：Allergy

authors： Spiteri MA,Bianco A,Strange RC,Fryer AA

更新日期：2000-01-01 00:00:00

abstract：:With an indirect immunofluorescence technique 77% of 96 patients with type I allergy and 40% of 20 patients with intrinsic bronchial asthma showed positive reactions for IgG anti-IgG antibodies in serum. They were present partly in an aggregated state not directly detectable before treatment with dithiothreitol. The a...

journal_title：Allergy

authors： Egeskjold EM,Permin H,Nielsen I,Sørensen HJ,Osterballe O,Kallerup HE

更新日期：1981-11-01 00:00:00

abstract：:In 77 consecutive patients with grass pollen rhinitis as the only allergic disease, treatment with sodium cromoglycate (SCG) nasal spray, hyposensitization with aluminium hydroxide adsorbed extract of grass pollen as perennial treatment, and a combination of the two was compared. Specific serum-IgE, IgG and IgG4 were ...

journal_title：Allergy

authors： Andersen NH,Jeppesen F,Schiøler T,Osterballe O

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Group 2 innate lymphoid cells (ILC2s) were closely associated with asthma. However, there were no perspective studies about the effects of glucocorticoid on ILC2s in asthma patients. Our objective was to perform a perspective study and evaluate the ILC2 activity after glucocorticoid therapy in asthma patient...

journal_title：Allergy

authors： Yu QN,Guo YB,Li X,Li CL,Tan WP,Fan XL,Qin ZL,Chen D,Wen WP,Zheng SG,Fu QL

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Modulation of leukocyte recruitment through blocking of chemokine receptors has been proposed as an attractive therapeutic strategy. We have previously demonstrated that n-Nonanoyl-CC chemokine ligand 14 (NNY-CCL14), a modified analog of the naturally occurring chemokine CCL14(9-74) internalizes and desensit...

journal_title：Allergy

authors： Gupta S,Erdmann G,Schulz-Maronde S,Escher SE,Richter R,Forssmann WG,Elsner J,Forssmann U

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Recent studies showed the presence of a unique dust-mite fauna in the indoor environment of Singapore. Immediate hypersensitivity to these dust mites, along with other known indoor allergens, may play a role in the pathogenesis of allergic respiratory diseases. This study evaluated the sensitization rates of...

journal_title：Allergy

authors： Chew FT,Lim SH,Goh DY,Lee BW

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The capacity of inflammatory cells to adhere involves an array of adhesion molecules, and is critical to the inflammatory responses seen in childhood asthma. We aimed to determine the changes of intercellular adhesion molecule-1 (ICAM-1) and L-selectin expressed on peripheral blood (PB) T lymphocytes and nat...

journal_title：Allergy

authors： Lin SJ,Chang LY,Yan DC,Huang YJ,Lin TJ,Lin TY

更新日期：2003-01-01 00:00:00

abstract：:The yeast Pityrosporum orbiculare (P. orbiculare) is a member of the normal human cutaneous flora, but it is also associated with several clinical manifestations of the skin. We have previously observed IgE-binding components in P. orbiculare extracts, using sera from patients with atopic dermatitis. In the present st...

journal_title：Allergy

authors： Zargari A,Härfast B,Johansson S,Johansson SG,Scheynius A

更新日期：1994-01-01 00:00:00

abstract：:Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rh...

journal_title：Allergy

authors： Bousquet J,Schunemann HJ,Fonseca J,Samolinski B,Bachert C,Canonica GW,Casale T,Cruz AA,Demoly P,Hellings P,Valiulis A,Wickman M,Zuberbier T,Bosnic-Anticevitch S,Bedbrook A,Bergmann KC,Caimmi D,Dahl R,Fokkens WJ,Gris

更新日期：2015-11-01 00:00:00

abstract：:The hygiene hypothesis states that a reduced exposure to allergens in early life is solely implicated in the growing propensity for allergy sensitization. Important elements of the hypothesis include helminth infection, exposure to endotoxins, exposure to pets and growing up on a farm. However, the hygiene hypothesis ...

journal_title：Allergy

authors： Platts-Mills TA,Erwin E,Heymann P,Woodfolk J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The aim of this paper was to investigate the role of SLPI in patients with allergic rhinitis. From this point of view, we also examined leukocyte elastase, alpha1-antitrypsin, and albumin. SLPI is an inhibitor of serine proteases such as leukocyte elastase, cathepsin G, and mast-cell chymase. Since chymase i...

journal_title：Allergy

authors： Westin U,Lundberg E,Wihl JA,Ohlsson K

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The diagnosis of allergic reactions to drugs is difficult. Most skin tests are not standardized, and in vitro tests are needed to avoid provocation tests. Cross-linking of IgE on basophils is known to cause the release of both cysteinyl leukotriene (Cys-LT) and histamine. We aimed to evaluate the diagnostic ...

journal_title：Allergy

authors： Lebel B,Messaad D,Kvedariene V,Rongier M,Bousquet J,Demoly P

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Latex sensitivity is an increasing problem among health-care workers. Allergic responses are associated with changes in nitric oxide (NO) generation and the changes secondary to latex have not been described. METHODS:A total of 22 subjects comprising equal numbers of control volunteers and subjects with sel...

journal_title：Allergy

authors： Tan K,Bruce C,Birkhead A,Thomas PS

更新日期：2001-07-01 00:00:00

abstract：:The concentration of house-dust mites (Dermatophagoides pteronyssinus) was investigated in 96 Danish homes with one or more members suffering from asthma. The air-exchange rates, humidity, and temperature were measured in all the homes. A positive correlation was found between indoor air humidity and mite concentratio...

journal_title：Allergy

authors： Harving H,Korsgaard J,Dahl R

更新日期：1993-02-01 00:00:00

abstract：:Species of the Cupressaceae family are a worldwide cause of respiratory allergies. We used monoclonal antibodies (mAbs) to investigate the presence and the nature of cross-reacting epitopes shared by various components within Cupressus arizonica pollen extract (CaE) or by CaE and pollen extract from C. sempervirens (C...

journal_title：Allergy

authors： Barletta B,Tinghino R,Corinti S,Afferni C,Iacovacci P,Mari A,Pini C,Di Felice G

更新日期：1998-06-01 00:00:00