Nasal CpG oligodeoxynucleotide administration induces a local inflammatory response in nonallergic individuals.

abstract：BACKGROUND:Specific allergen immunotherapy (SIT) and nasal steroids (NS) are considered effective anti-inflammatory treatments for allergic rhinitis, although their mechanism of action differs. OBJECTIVE:The aim of this study was to examine the effect of treatment with NS and SIT on different populations of inflammato...

journal_title：Allergy

authors： Rak S,Heinrich C,Scheynius A

更新日期：2005-05-01 00:00:00

abstract：:The clinical effects in asthma of corticosteroids can be ascribed to their strong anti-inflammatory action. The pathophysiology of asthma is complex. A diversity of mediators and interactions between mediators and between mediators and various cell types enhances and maintains the inflammatory process in the airways r...

journal_title：Allergy

authors： Norn S,Clementsen P

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Health-related quality of Life in patients with chronic urticaria is evaluated by mean of generic instruments or questionnaire designed for skin diseases. No disease-specific tool is now available for the assessment of chronic urticaria impact from patients' viewpoint. OBJECTIVE:The aim of our study is to d...

journal_title：Allergy

authors： Baiardini I,Pasquali M,Braido F,Fumagalli F,Guerra L,Compalati E,Braga M,Lombardi C,Fassio O,Canonica GW

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Allergic diseases have become a major public health problem in developed countries; yet, no reliable, safe and consistently effective treatment is available. DNA immunization has been shown to prevent and balance established allergic responses, however, the high dose of conventional DNA vaccines necessary fo...

journal_title：Allergy

authors： Scheiblhofer S,Gabler M,Leitner WW,Bauer R,Zoegg T,Ferreira F,Thalhamer J,Weiss R

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:We report on a 21-year-old atopic woman who developed urticaria, angioedema of the face, and wheezy dyspnea shortly after drinking beer and after eating a corn-made snack. METHODS:Skin prick tests and specific IgE determinations to beer ingredients and cereal extracts were performed. Immunoblotting inhibiti...

journal_title：Allergy

authors： Figueredo E,Quirce S,del Amo A,Cuesta J,Arrieta I,Lahoz C,Sastre J

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice is nonsedating antihistamines, dosages of which may be increased up to fourfold if standard doses are ineffecti...

journal_title：Allergy

authors： Krause K,Spohr A,Zuberbier T,Church MK,Maurer M

更新日期：2013-07-01 00:00:00

abstract：:The possible dependence of the dual cutaneous reaction (DCR) on activation of the complement and coagulation systems was further elucidated. Heterologous whole anti-human IgE was injected intradermally (i.d.) on the volar aspect of the forearms of 17 drug-free healthy volunteers and venous samples for the selected lab...

journal_title：Allergy

authors： Grönneberg R

更新日期：1985-11-01 00:00:00

abstract：:This study evaluated the risk factors for developing allergic reactions to alternative drugs such as acetaminophen and nimesulide in 367 patients intolerant of nonsteroidal anti-inflammatory drugs (NSAID) compared to 243 healthy controls. All subjects were given test doses (TD) of acetaminophen and nimesulide, and age...

journal_title：Allergy

authors： Pastorello EA,Zara C,Riario-Sforza GG,Pravettoni V,Incorvaia C

更新日期：1998-09-01 00:00:00

abstract：:Indications for in vitro fertilization (IVF) have been cautiously extended over the years. IVF is usually considered to be a technically complex method with only minimal side-effects. We report the case of a woman who developed an anaphylactic reaction during IVF immediately after the embryo transfer. ...

journal_title：Allergy

authors： Abeck D,Kuwert C,Segnini-Torres M,Przybilla B,Ring J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Food allergy in children can be life-threatening. Component-resolved diagnostics approach to food anaphylaxis is rarely assessed in children. The aim of the study was to identify the food allergen components as the triggers responsible for severe anaphylaxis, with regard to characteristics and associated ris...

journal_title：Allergy

authors： Blazowski L,Majak P,Kurzawa R,Kuna P,Jerzynska J

更新日期：2019-10-01 00:00:00

abstract：:Oral immunotherapy (IT) was evaluated in a pilot study in two centres in children aged 8-15 years with allergic rhinoconjunctivitis. High doses (up to 20 X 10(6) BU monthly) of a defined freeze-dried birch pollen extract administered in enteric-coated gelatine capsules were given either daily for seven consecutive day...

journal_title：Allergy

authors： Björkstén B,Möller C,Broberger U,Ahlstedt S,Dreborg S,Johansson SG,Juto P,Lanner A

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Exposure and contact with bee moth (Galleria mellonella) larvae (Gm) can cause an allergic reaction both in anglers and breeders. We described the case of an amateur fisherman who experienced an allergic reaction using Gm but not using heat-treated Gm (h-Gm) (mummies). The aim of this study was to demonstrat...

journal_title：Allergy

authors： Villalta D,Martelli P,Mistrello G,Roncarolo D,Zanoni D

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Polcalcins are pollen-specific allergens with two EF-hand calcium-binding sites that exhibit strong cross-reactivity. Our objective was to isolate and express the cDNA coding of the EF-hand calcium-binding allergen from lilac pollen and to study cross-reactivity with other polcalcins from related and nonrela...

journal_title：Allergy

authors： Ledesma A,Barderas R,Westritschnig K,Quiralte J,Pascual CY,Valenta R,Villalba M,Rodríguez R

更新日期：2006-04-01 00:00:00

abstract：:Leukotrienes are a recently discovered group of arachidonic acid-derived lipid mediators. Using radioimmunoassay and high pressure liquid chromatography (HPLC), we have identified the SRS-A sulphidopeptide leukotrienes (LTC4, LTD4 and LTE4) in nasal washings from patients with allergic rhinitis who underwent nasal cha...

journal_title：Allergy

authors： Shaw RJ,Fitzharris P,Cromwell O,Wardlaw AJ,Kay AB

更新日期：1985-01-01 00:00:00

abstract：:Exposure to natural rubber latex (NRL) medical gloves poses risks to patients sensitized to NRL and to users of protective gloves. Previous studies have shown that extractable allergen levels of the gloves vary widely. Since most of the available laboratory methods of NRL allergen measurement lack adequate validation,...

journal_title：Allergy

authors： Palosuo T,Mäkinen-Kiljunen S,Alenius H,Reunala T,Yip E,Turjanmaa K

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Patients with nonallergic asthma frequently show autoreactivity as do subjects with chronic urticaria (CU). Activation of the coagulation cascade and hyper-expression of vascular endothelial growth factor (VEGF) were recently found in CU, and there is sparse evidence that the same may occur in asthma. OBJEC...

journal_title：Allergy

authors： Asero R,Tedeschi A,Cugno M

更新日期：2011-10-01 00:00:00

abstract：:Work-related asthma is the most common occupational respiratory disorder in the industrialized countries. It has been postulated that wood dust exposure may increase the risk of work-related asthma. The objective of this study was to assess, through a meta-analysis, the risk of developing work-related asthma associate...

journal_title：Allergy

authors： Pérez-Ríos M,Ruano-Ravina A,Etminan M,Takkouche B

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

journal_title：Allergy

authors： Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The genetic determinants of food allergy have not been systematically reviewed. We therefore systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation. METHODS:We searched three electronic databases (MEDLINE, EMBASE and PubMed) on 9 January 2018...

journal_title：Allergy

authors： Suaini NHA,Wang Y,Soriano VX,Martino DJ,Allen KJ,Ellis JA,Koplin JJ

更新日期：2019-09-01 00:00:00

abstract：:In 30 stable asthmatics, a comparison was made between the changes in pulmonary function (FEV1, FVC, PEF, MEF75, MEF50 and MEF25) hourly for 9 h after a single dose of inhaled budesonide 1,600 micrograms, and placebo. All subjects used inhaled steroids daily; this medication was, however, withheld 8 days prior to the ...

journal_title：Allergy

authors： Engel T,Dirksen A,Heinig JH,Nielsen NH,Weeke B,Johansson SA

更新日期：1991-10-01 00:00:00

abstract：:Topical corticosteroids have proved to be effective in the treatment of allergic rhinitis. The symptomatology of allergic rhinitis is considered to be the result of the accumulation and activation of inflammatory cells and cytokine release and hence the efficacy of corticosteroids is associated with their anti-inflamm...

journal_title：Allergy

authors： Fokkens WJ,Godthelp T,Holm AF,Blom H,Klein-Jan A

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The Gaining Optimal Asthma ControL (GOAL) study has shown the superiority of a combination of salmeterol/fluticasone propionate (SFC) compared with fluticasone propionate alone (FP) in terms of improving guideline defined asthma control. METHODS:Clinical and economic data were taken from the GOAL study, sup...

journal_title：Allergy

authors： Briggs AH,Bousquet J,Wallace MV,Busse WW,Clark TJ,Pedersen SE,Bateman ED,GOAL Investigators Group.

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the ocular surface disease in atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC) has not been fully understood. We tried to clarify the differences in the ocular surface status in patients with AKC, VKC, and healthy control subjects. METHODS:Twenty-four eyes of 12 AK...

journal_title：Allergy

authors： Hu Y,Matsumoto Y,Dogru M,Okada N,Igarashi A,Fukagawa K,Tsubota K,Fujishima H

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Although atopic sensitization is one of the strongest risk factors for asthma, its relationship with asthma is poorly understood. We hypothesize that 'atopy' encompasses multiple sub-phenotypes that relate to asthma in different ways. METHODS:In two population-based birth cohorts (Manchester and Isle of Wig...

journal_title：Allergy

authors： Lazic N,Roberts G,Custovic A,Belgrave D,Bishop CM,Winn J,Curtin JA,Hasan Arshad S,Simpson A

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Children with spina bifida (SB) are exposed to latex soon after birth during bladder catheterization, rectal disimpaction, and multiple surgical procedures. IgE-mediated latex-allergic reactions have been reported recently in these children. Our study was designed to assess the prevalence of allergic reactio...

journal_title：Allergy

authors： Kattan H,Harfi H,Tipirneni P

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Since 1988, numerous allergen immunotherapy guidelines (AIT-GLs) have been developed by national and international organizations to guide physicians in AIT. Even so, AIT is still severely underused. OBJECTIVE:To evaluate AIT-GLs with AGREE-II, developed in 2010 by McMaster University methodologists to compr...

journal_title：Allergy

authors： Larenas-Linnemann DES,Antolín-Amérigo D,Parisi C,Nakonechna A,Luna-Pech JA,Wedi B,Davila I,Gómez M,Levin M,Ortega Martell JA,Klimek L,Rosario N,Muraro AM,Agache I,Bousquet J,Sheikh A,EAACI International Societies Council.

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Several studies showed that calcium-binding proteins have a fixed place in the spectrum of allergenic substances. Often the binding of a calcium ion induces conformational changes and affects immunoglobulin E-binding to the allergen. Hence, the quantitative characterization of the binding to calcium is of im...

journal_title：Allergy

authors： Hebenstreit D,Ferreira F

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:While immediate-type clinical reactions to food can quite easily be identified by history or measurement of specific IgE in combination with positive oral food challenges, the evaluation of food allergy in the absence of immediate clinical reactions still presents diagnostic difficulties--particularly in chi...

journal_title：Allergy

authors： Niggemann B,Reibel S,Wahn U

更新日期：2000-03-01 00:00:00

abstract：:A total of 109 subjects reporting symptoms indicating type I hypersensitivity reactions to natural rubber latex (NRL) gloves was included in this study, and 66 of them had latex-specific IgE antibodies. They underwent provocation tests by wearing two types of NRL gloves with high (n=103) and low (n=75) allergen conten...

journal_title：Allergy

authors： Baur X,Chen Z,Allmers H,Raulf-Heimsoth M

更新日期：1998-04-01 00:00:00

abstract：:Skin tests and estimation of specific IgE-antibodies by the RAST are evaluated as diagnostic procedures in bee sting hypersensitivity with the followiny extracts. (2) With bee venom results of skin tests and RAST correspond in 82%, with bee wholebody extracts in 68%. (3) Both with skin tests and the RAST with bee veno...

journal_title：Allergy

authors： Patrizzi R,Müller U,Yman L,Hoigné R

更新日期：1979-08-01 00:00:00