Abstract:
:All eight production workers from a small trout-processing factory were studied because of respiratory or rhinitis symptoms when working next to the automatic gutting machine. Seven of the eight had positive histamine provocation tests. Four patients had elevated total IgE levels while one had a slightly elevated eosinophil count. All workers had either weakly or moderately positive RAST against contaminated water from the outlet drain of the gutting machine. This water contained 1 microgram endotoxin/ml. We concluded that five of the workers had probably developed occupationally related asthma from inhalation of contaminated aerosol from the gutting machine. Inhalation of endotoxin from gram-negative bacteria may be the cause of this disorder. An alternative explanation is a Type I allergy caused by fish or bacterial protein with or without a simultaneous effect of endotoxin.
journal_name
Allergyjournal_title
Allergyauthors
Sherson D,Hansen I,Sigsgaard Tdoi
10.1111/j.1398-9995.1989.tb00455.xsubject
Has Abstractpub_date
1989-07-01 00:00:00pages
336-41issue
5eissn
0105-4538issn
1398-9995journal_volume
44pub_type
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