Dysregulation of the behavioral activation system in remitted bipolar I disorder.

Abstract:

:The current study tests a prediction of the behavioral activation system (BAS) dysregulation theory of bipolar disorder, namely that following high levels of reward or frustration, individuals with bipolar disorder will take longer than will healthy controls to recover to baseline levels of BAS activity. Eighty individuals (40 with bipolar I disorder, currently euthymic; 40 with no history of affective disorder) completed a daily diary over a 28 day period. No differences were found between the 2 groups in terms of the relation among levels of reward or frustration experienced, magnitude of initial response, or time taken to recover. However, examination of the relation between number of previous episodes and time to recover revealed that history of mania was associated with prolonged activation following reward, whereas history of both mania and depression were associated with prolonged recovery following frustration. The findings do not support an association between lifetime diagnosis of bipolar disorder and slow recovery of BAS activity. Nevertheless, they offer tentative support for an association between number of previous episodes and slow recovery of BAS activity.

journal_name

J Abnorm Psychol

authors

Wright KA,Lam D,Brown RG

doi

10.1037/a0013598

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

838-848

issue

4

eissn

0021-843X

issn

1939-1846

pii

2008-16252-010

journal_volume

117

pub_type

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