Abstract:
:In early life, patients with sickle cell disease (SCD) can have acute, life-threatening emergencies related to splenic hypofunction (overwhelming bacterial sepsis), as well as anemic crises from acute splenic sequestration because of sudden pooling of blood in the spleen. The landmark penicillin prophylaxis study in 1985 showed a remarkable decrease in mortality from sepsis in young children with SCD who were treated with oral penicillin prophylaxis compared to placebo. Since that study, newborns are screened for SCD and placed on oral penicillin prophylaxis in nearly all of the United States, as well as in other countries where the disease is highly prevalent. The previously described permanent, complete and nearly universal "autosplenectomy" emerging by late childhood or early adulthood is now challenged by recent findings of reversibility of splenic dysfunction by the antisickling drug hydroxyurea or by successful allogeneic stem cell transplantation, even in older patients. Imaging techniques for hypofunction of the spleen are the most commonly used modalities to guide the clinician in decisions regarding medical or surgical management.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Khatib R,Rabah R,Sarnaik SAdoi
10.1007/s00247-008-1049-9subject
Has Abstractpub_date
2009-01-01 00:00:00pages
17-22issue
1eissn
0301-0449issn
1432-1998journal_volume
39pub_type
杂志文章,评审abstract::The aim of this review is to emphasize the role of fetal MR in the evaluation of the supratentorial space. The advantages of MRI compared to US are stressed in three fields of application: cerebral biometry, sulcation and cerebral parenchyma. In each field, normal data are displayed and MR applications with patterns o...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-004-1249-x
更新日期:2004-09-01 00:00:00
abstract::Intravesical catheter knotting during micturating cystourethrography is a rare but recognized complication of the procedure. We were able to untangle a knot utilizing a fluoroscopically guided vascular guidewire. Following this success, a small study was performed using a model. Various types of guidewires and techniq...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-007-0426-0
更新日期:2007-04-01 00:00:00
abstract::Two cases are presented of children who demonstrated complete absence of bone marrow signal on MR imaging of the spine following bone marrow transplantation. The possible causes for these appearances are discussed. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02018628
更新日期:1991-01-01 00:00:00
abstract::Fetus in fetu is a rare pathological condition, presenting as a congenital tumor. It consists of a malformed parasitic twin that is found within the body of its sibling. Less than 70 cases have been reported and in most of them a definite diagnosis was only made during surgery. We present a case with two fetuses in th...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012747
更新日期:1994-01-01 00:00:00
abstract::We report a 29-month-old girl with osteopathia striata with cranial sclerosis (OS-CS), who showed several unusual manifestations, including short stature, muscular hypotonia, short lingual frenulum, an accessory ear and a granuloma at the oral edge. The most unusual distressing finding was severe cervical kyphosis wit...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470100486
更新日期:2001-09-01 00:00:00
abstract::We present the CT and MRI findings of an 8-day-old infant with an infected cephalhaematoma complicated by skull osteomyelitis, venous sinus thrombosis and left cerebellar haemorrhage. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-001-0647-6
更新日期:2002-05-01 00:00:00
abstract::The risks associated with total splenectomy, including overwhelming postsplenectomy infection, have led to an interest in the use of partial splenectomy as an alternative surgical option for children with congenital hemolytic anemias and hypersplenism. Partial splenectomy, a procedure designed to remove enough spleen ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-009-1519-8
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Hirschsprung disease (HD) is a functional obstruction of the bowel caused by the absence of intrinsic enteric ganglion cells. The diagnosis of total colonic HD (TCHD) based on contrast enemas is difficult in newborns because radiological findings vary. OBJECTIVE:To evaluate the radiographic and contrast ene...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-008-0952-4
更新日期:2008-11-01 00:00:00
abstract::Contrast-enhanced ultrasound (CEUS) and diffusion-weighted imaging (DWI) are safe, repeatable imaging techniques. The aim of this paper is to discuss the advantages, technical factors and possible clinical applications of these imaging tools in focal renal lesions in children. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-019-04552-9
更新日期:2020-02-01 00:00:00
abstract::Magnetic resonance (MR) images of 12 pathologically proven lesions of Langerhans cell histiocytosis (LCH) of bone were reviewed retrospectively. MR identified all lesions, three of which were not identified on plain radiographs. In all cases, MR showed greater abnormality than did plain radiographs. With one exception...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02017655
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Influenza A (H1N1) can cause severe neurological complications. OBJECTIVE:The purpose of this study was to analyze clinical and MRI features of neurological complications after H1N1 infection in critically ill children. MATERIALS AND METHODS:We retrospectively analyzed clinical and neuroimaging findings in...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2682-5
更新日期:2013-09-01 00:00:00
abstract::Sternal clefts have been reported sporadically, but there are no reports describing complete investigations of the malformation. We describe a child with isolated inferior sternal cleft diagnosed at 33 weeks of gestation and thoroughly investigated by prenatal US, MRI and CT and preoperative US. Our report highlights ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2318-6
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Various reports support the use of cervical spine (c-spine) CT over conventional radiography in screening of c-spine injury. Interest now exists in diagnostic radiation-induced morbidity. OBJECTIVE:To estimate excess relative risk for developing cancer from c-spine high-resolution CT radiation exposure. MA...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-007-0728-2
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:The diagnosis of Hirschsprung's disease is usually made in neonates but often considered in older infants and children with constipation: these children may be referred for barium enema. Since it is widely accepted that a normal barium enema does not exclude Hirschsprung's disease, some children, after a nor...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000298
更新日期:2000-10-01 00:00:00
abstract::A 10-year-old girl presented with a cerebral malignant ectomesenchymoma (MEM), a very unusual tumour with undifferentiated mesenchymal as well as ectodermal elements. Somatostatin receptor scintigraphy (SRS) was performed during the diagnostic workup. The recurrent residual tumour mass was exactly visualized with SRS,...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000404
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Different iterative reconstruction techniques are available for use in pediatric computed tomography (CT), but these techniques have not been systematically evaluated in infants. OBJECTIVE:To determine the effect of iterative reconstruction on diagnostic performance, image quality and radiation dose in infa...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-015-3281-4
更新日期:2015-07-01 00:00:00
abstract::Three-dimensional printing called rapid prototyping, a technology that is used to create physical models based on a 3-D computer representation, is now commercially available and can be created from CT or MRI datasets. This technical innovation paper reviews the specific requirements and steps necessary to apply biome...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2788-9
更新日期:2014-02-01 00:00:00
abstract::Primary malignant tumours of the stomach are very rare in children, most being lymphomas and sarcomas. The majority of primary gastric lymphomas are high-grade non-Hodgkin's lymphomas and are of B-cell origin. However, a significant number are low-grade B-cell lymphomas that are derived from mucosa-associated lymphoid...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-001-0598-y
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:To examine the extent to which intracranial pressure (ICP) in children after severe brain trauma can be determined by cranial CT. MATERIALS AND METHODS:Two experienced paediatric radiologists, without any knowledge of the clinical symptoms, evaluated 124 CT scans from 65 children (average age 5.4 years) who ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000255
更新日期:2000-07-01 00:00:00
abstract::The neurosonograms of fifty-eight patients treated over a four-year period with ECMO support were retrospectively reviewed for analysis of changes in interhemispheric (IHF) width while on ECMO. To correlate these measurements with patterns of development of total body edema as reflected by chest wall thickening on por...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02010805
更新日期:1990-01-01 00:00:00
abstract::Two patients with different patterns of soft tissue and bone involvement demonstrate the variability of extracutaneous manifestations of juvenile xanthogranuloma, a non-X histiocytosis, better known to dermatologists than to radiologists. ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/BF02016261
更新日期:1992-01-01 00:00:00
abstract::A 14-year-old girl presented with symptoms and signs of left otomastoiditis and meningitis. CT and MRI revealed a largely expanded cavum septum pellucidum with enhancing walls and findings suggesting left otomastoiditis and meningitis. At surgery, an abscess was found within the cavum septum pellucidum. Five similar c...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-003-0925-6
更新日期:2003-07-01 00:00:00
abstract::Cranial sonography plays an important role in the initial evaluation of infants with suspected bacterial meningitis and in monitoring for complications of the disease. Echogenic widening of the brain sulci, meningeal thickening and hyperemia suggest the diagnosis in an at-risk population. Sonography can identify the p...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-007-0538-6
更新日期:2008-02-01 00:00:00
abstract::beta-Thalassaemia major is a hereditary haemolytic anaemia that is treated with multiple blood transfusions. A major complication of this treatment is iron overload, which leads to cell death and organ dysfunction. Chelation therapy, used for iron elimination, requires effective monitoring of the body burden of iron, ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-007-0567-1
更新日期:2007-12-01 00:00:00
abstract::Barium esophagrams were obtained in two patients with respiratory problems whose underlying congenital heart disease was pseudotruncus arteriosus type I. The esophagrams revealed vascular indentations on the esophagus, one posteriorly, and the other anteriorly. Both types of indentations were secondary to aorto-pulmon...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02021532
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Magnetic resonance imaging (MRI) of the hips is being increasingly used to confirm hip reduction after surgery and spica cast placement for developmental dysplasia of the hip (DDH). OBJECTIVE:To review a single institutional experience with post-spica MRI in children undergoing closed or open hip reduction ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-018-4143-7
更新日期:2018-08-01 00:00:00
abstract::We present an unusual case of severe hydranencephaly in a term infant who presented with the following additional unique features, which were discovered on CT, MRI and MR angiography examinations: (1) occlusion of the bilateral posterior cerebral arteries, (2) absence of the occipital lobes, (3) an ovoid calcified mas...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1894-1
更新日期:2011-02-01 00:00:00
abstract::We review our experience with unusual ocular pathologies, some mimicking retinoblastoma, that were referred to our institution during the past two decades. After presenting the imaging anatomy of the normal eye, we discuss pertinent clinical and pathological features, and illustrate the US and MRI appearance of retino...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-012-2374-6
更新日期:2012-06-01 00:00:00
abstract::Following bacterial meningitis thirty cases of enlarging head were evaluated on ultrasound to find out the cause. Nine out of 30 patients had multiple cystic lesions in both cerebral hemispheres with or without ventriculomegaly. Three patients showed debris in the cysts suggesting pus, which was confirmed on ultrasoun...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02395750
更新日期:1988-01-01 00:00:00
abstract::Twelve children with suspected septic arthritis of the elbow were prospectively studied with plain-film radiography and ultrasound. Imaging data were correlated with clinical history and final diagnosis. Joint effusion was seen by sonography in six patients, four of whom underwent ultrasound-guided joint aspiration, c...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02015794
更新日期:1995-01-01 00:00:00