Abstract：
:Although addiction is a uniquely human phenomenon, some of its pathognomonic features can be modeled at the animal level. Such features include the euphoric "high" produced by acute administration of addictive drugs; the dysphoric "crash" produced by acute withdrawal; drug-seeking and drug-taking behaviors; and relapse to drug-seeking behavior after achieving successful abstinence. Animal models exist for each of these features. In this review, I focus on various animal models of addiction and how they can be used to search for clinically effective antiaddiction medications. I conclude by noting some of the new and novel medications that have been developed preclinically using such models and the hope for further developments along such lines.
journal_name
Curr Psychiatry Repjournal_title
Current psychiatry reportsauthors
Gardner ELdoi
10.1007/s11920-008-0061-ysubject
Has Abstractpub_date
2008-10-01 00:00:00pages
377-84issue
5eissn
1523-3812issn
1535-1645journal_volume
10pub_type
杂志文章abstract：PURPOSE OF REVIEW:The aim of this review was to focus solely on youths' behavioral responses to natural disasters and political conflicts in order to fully understand their impact and scope. RECENT FINDINGS:Recent studies in the field of trauma have shown that theoretical conceptions have moved away from a narrow focu...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-019-1030-3
更新日期：2019-04-29 00:00:00
abstract：:Empathy is an important psychological process that facilitates human communication and interaction. Enhancement of empathy has profound significance in a range of applications. In this paper, we review emerging directions of research on computational analysis of empathy expression and perception as well as empathic in...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-016-0682-5
更新日期：2016-05-01 00:00:00
abstract：:Anticoagulants and psychotropic medications are commonly prescribed together. Thus, the potential for interaction exists. Whereas thrombolytics and heparins are implicated in few pharmacokinetic interactions, warfarin and platelet inhibitors have been implicated in various interactions with psychotropic medications. I...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-010-0120-z
更新日期：2010-06-01 00:00:00
abstract：:Knowledge of gonadal hormone-related influences on human brain anatomy, function, and chemistry is scarce. The present review scrutinized organizational and functional neuroimaging correlates of the menstrual cycle and premenstrual dysphoric disorder (PMDD). Supportive evidence of cyclic short-term structural and func...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-015-0619-4
更新日期：2015-10-01 00:00:00
abstract：PURPOSE OF REVIEW:We review topical evidence on ethical issues in conducting disaster research with children and families affected by natural disasters, with an emphasis on analyzing specific vulnerabilities associated with children and families affected by disasters, identifying significant findings and trends of ethi...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-018-0902-2
更新日期：2018-05-18 00:00:00
abstract：:Few treatments for eating disorders have established a base of empirical support, and those that have are still limited by high dropout rates and low abstinence rates. Thus, there is a critical need for innovative eating disorder treatments to fill this gap. The past decade has seen a surge in the development of novel...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-013-0407-y
更新日期：2013-11-01 00:00:00
abstract：:The field of neuroimaging of attention-deficit/hyperactivity disorder (ADHD) is now 30 years old. This brief selective review highlights the increasing sophistication of recent structural and functional neuroimaging studies of ADHD. In volumetric studies, investigators are examining extra-frontal, as well as frontal-s...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-007-0052-4
更新日期：2007-10-01 00:00:00
abstract：:After dividing clinicians for almost 70 years, Charles Bonnet syndrome has reached an impasse. Defined by a neurologist in the 1930s, the syndrome was intended to eponymize the association of visual hallucinations with age, but evolved into one describing their association with eye disease or, more recently, an etiolo...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-005-0050-3
更新日期：2005-06-01 00:00:00
abstract：:Interferon (IFN) therapy is associated with neuropsychiatric side effects including cognitive dysfunction and mood syndromes of varying severity. These problems are the most common causes of treatment discontinuation. Dose and duration of treatment influence risk of IFN-induced side effects. Rates of IFN-induced depre...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-005-0042-3
更新日期：2005-10-01 00:00:00
abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a theoretical explanation and a review of the recent literature concerning the role of neuroactive steroids in perinatal depression, and to use this information to suggest future directions of research. RECENT FINDINGS:The bulk of the evidence on neuroactive s...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-018-0937-4
更新日期：2018-08-09 00:00:00
abstract：:A recent publication focused on biomarkers of future suicidal behaviors identifies several genes expressed in high-risk states among four samples. We discuss the implications of this study as well as the current state of research regarding biomarkers of suicidal behavior. ...
journal_title：Current psychiatry reports
pub_type： 评论,杂志文章
doi：10.1007/s11920-013-0424-x
更新日期：2013-12-01 00:00:00
abstract：PURPOSE OF REVIEW:There are frequent and diverse psychosocial issues that afflict patients with head and neck cancer (HNC) across the illness trajectory, prompting a focus on clinical interventions to prevent and mitigate psychosocial distress. We sought to characterize current understanding on the cause, effects, and ...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-017-0811-9
更新日期：2017-09-01 00:00:00
abstract：PURPOSE OF REVIEW:The purpose of this paper was to provide a comprehensive narrative review of the relationship between physical activity (PA) and anxiety and the rationale for including it as a treatment option for anxiety disorders. Several gaps in the literature are highlighted alongside recommendations for future r...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-018-0923-x
更新日期：2018-07-24 00:00:00
abstract：:The present review examines the moderating role of ideology on the effects of war, armed conflict, and terrorism on youth. Ideology is an important factor given the central role played by religio-political ideology and nationalism in present-day conflicts. Ideologies or worldviews represent cognitive frameworks that i...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-016-0684-3
更新日期：2016-05-01 00:00:00
abstract：:Animal models may be useful in investigating the fundamental mechanisms underlying psychiatric disorders, and may contribute to the development of new medications. A computerized literature search was used to collect studies on recently developed animal models for anxiety disorders. Particular cognitive-affective proc...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-003-0056-7
更新日期：2003-08-01 00:00:00
abstract：:The authors review the literature from the last year examining the benefits of cholinesterase inhibitors in the treatment of behavioral disturbance in Alzheimer's disease (AD) and other dementias. Previous review has indicated that cholinesterase inhibitors have psychotropic properties. We found more evidence to suppo...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-001-0061-7
更新日期：2001-06-01 00:00:00
abstract：:Anorexia nervosa is a debilitating illness that affects mostly females and their families. Multiple physiologic disturbances are present and can be life-threatening. Nutritional rehabilitation is the foremost initial treatment goal. Assessment skills include understanding the physiologic, developmental, and psychiatri...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-010-0174-y
更新日期：2011-04-01 00:00:00
abstract：:The comorbidity of anxiety disorders with pain has received little research attention even though recent studies show that these disorders are as likely to co-occur with chronic pain conditions as depressive disorder. Comorbid anxiety has implications for the impact and outcome of pain conditions. Even though it may b...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-008-0051-0
更新日期：2008-08-01 00:00:00
abstract：:There is a dearth of knowledge regarding the diagnosis and treatment of bipolar disorder in late life. Based on a review of the current research on bipolar disorder in late life, emerging areas of research were identified: 1) methodological challenges in diagnosing bipolar disorder; 2) a lack of guidelines for the tre...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-005-0018-3
更新日期：2005-03-01 00:00:00
abstract：:Studies published between the beginning of 2013 and May 2015 on the neuropsychological functioning of patients with anorexia nervosa compared with healthy participants framed in the context of the Research Domain Criteria matrix identifies evidence for functional differences in three domains: Negative Valance Systems-...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-015-0651-4
更新日期：2016-02-01 00:00:00
abstract：:A growing body of evidence suggests that depressive disorders and anxiety disorders are much more prevalent among medically ill children and adolescents when compared with the general population, and that the presence of comorbidity may adversely affect medical outcomes and quality of life. Whereas the prevalence and ...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-007-0080-0
更新日期：2007-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Neuroactive steroid hormones, such as estradiol and progesterone, likely play a role in the pathophysiology of female-specific psychiatric disorders such as premenstrual dysphoric disorder (PMDD) and postpartum depression and may contribute to the marked sex differences observed in the incidence and p...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-018-0906-y
更新日期：2018-05-18 00:00:00
abstract：:Descriptions of mental illness exist throughout recorded history. However, until the mid-twentieth century, there was no standard nosology or diagnostic standard for mental disorders. This limited understanding of these disorders and development of better treatments. As conditions such as dementia praecox and schizoph...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-013-0409-9
更新日期：2013-11-01 00:00:00
abstract：:The Surgeon General's National Action Agenda highlighted key issues that challenge the public health system in appropriately meeting the mental health needs of children and their families. Among these issues included the need for screening and early identification, improving access to appropriate mental health care, s...
journal_title：Current psychiatry reports
pub_type： 杂志文章
doi：10.1007/s11920-002-0042-5
更新日期：2002-04-01 00:00:00
abstract：:Bipolar disorder (BD) is a complex disorder with a range of presentations. BD is defined by the presentation of symptoms of mania or depression, with classification dependent on patient/family reports and behavioural observations. Recent work has investigated the biological underpinnings of BD, highlighting the role p...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-014-0541-1
更新日期：2015-02-01 00:00:00
abstract：PURPOSE OF REVIEW:We review recent and growing evidence that provides support for a novel parasomnia, trauma associated sleep disorder (TASD). Based on these findings, we further develop the clinical and polysomnographic (PSG) characteristics of TASD. We also address factors that precipitate TASD, develop a differentia...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-019-1066-4
更新日期：2019-08-13 00:00:00
abstract：:By design or by default, primary care providers (PCPs)are frequently the vanguard in the fight against suicide. Recent studies have highlighted programs to improve screening and prevention of suicidality in the medical home, particularly among high-risk patients, such as adolescents, the elderly, and veterans. Increas...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-012-0286-7
更新日期：2012-08-01 00:00:00
abstract：:Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous disorder characterized by inattention, impulsivity, and/or hyperactivity in children and adults. Putative environmental risk factors for ADHD include toxin and prenatal smoke exposure, low socioeconomic status, and parental marital instability and disc...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-009-0058-1
更新日期：2009-10-01 00:00:00
abstract：:The cognitive model of OCD suggests that misinterpreting intrusive thoughts as unacceptable leads to increased anxiety and attempts to suppress or ignore the thoughts through avoidance or compulsive rituals. An insidious negative feedback loop develops as one's attention focuses on these thoughts and in turn the unwan...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-013-0357-4
更新日期：2013-05-01 00:00:00
abstract：PURPOSE OF REVIEW:We review recent empirical investigations about two core processes subtending impairments in interpersonal functioning and, more precisely, cooperative behaviors in personality disorders: Trust toward others and rejection sensitivity. The main contributions are about borderline and narcissistic person...
journal_title：Current psychiatry reports
pub_type： 杂志文章,评审
doi：10.1007/s11920-019-1059-3
更新日期：2019-07-01 00:00:00
