Genomic characterisation, chromosomal assignment and in vivo localisation of the canine high mobility group A1 (HMGA1) gene.

abstract：BACKGROUND:Genetic markers conferring susceptibility to diabetes specific renal disease remains to be identified for early prediction and development of effective drugs and therapies. Inconsistent results obtained from analysis of genes from classical pathways generate need for examination of unconventional genetic mar...

journal_title：BMC genetics

authors： Prasad P,Kumar KM,Ammini AC,Gupta A,Gupta R,Thelma BK

更新日期：2008-03-22 00:00:00

abstract：BACKGROUND:Drought is one of the most important abiotic stresses causing drastic reductions in yield in rainfed rice environments. The suitability of grain yield (GY) under drought as a selection criterion has been reported in the past few years. Most of the quantitative trait loci (QTLs) for GY under drought in rice r...

journal_title：BMC genetics

authors： Vikram P,Swamy BP,Dixit S,Ahmed HU,Teresa Sta Cruz M,Singh AK,Kumar A

更新日期：2011-10-18 00:00:00

abstract：BACKGROUND:The human Prader-Willi syndrome (PWS) domain and its mouse orthologue include a cluster of paternally expressed genes which imprinted expression is co-ordinately regulated by an imprinting center (IC) closely associated to the Snurf-Snrpn gene. Besides their co-regulated imprinted expression, two observation...

journal_title：BMC genetics

authors： Watrin F,Le Meur E,Roeckel N,Ripoche MA,Dandolo L,Muscatelli F

更新日期：2005-01-05 00:00:00

abstract：BACKGROUND:Anopheles gambiae females are the world's most successful vectors of human malaria. However, a fraction of these mosquitoes is refractory to Plasmodium development. L3-5, a laboratory selected refractory strain, encapsulates transforming ookinetes/early oocysts of a wide variety of Plasmodium species. Previo...

journal_title：BMC genetics

authors： Zheng L,Wang S,Romans P,Zhao H,Luna C,Benedict MQ

更新日期：2003-10-24 00:00:00

abstract：BACKGROUND:Kernel length is an important target trait in barley (Hordeum vulgare L.) breeding programs. However, the number of known quantitative trait loci (QTLs) controlling kernel length is limited. In the present study, we aimed to identify major QTLs for kernel length, as well as putative candidate genes that migh...

journal_title：BMC genetics

authors： Zhou H,Liu S,Liu Y,Liu Y,You J,Deng M,Ma J,Chen G,Wei Y,Liu C,Zheng Y

更新日期：2016-09-13 00:00:00

abstract：:Three variants of the confidence set inference (CSI) procedure were proposed and applied to both the simulated and the Collaborative Study on the Genetics of Alcoholism (COGA) data. For each of the two applications, we first performed a preliminary genome scan study based on the microsatellite markers using the GENEHU...

journal_title：BMC genetics

authors： Papachristou C,Lin S

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:Cattle are bred for, amongst other factors, specific traits, including parasite resistance and adaptation to climate. However, the influence and inheritance of mitochondrial DNA (mtDNA) are not usually considered in breeding programmes. In this study, we analysed the mtDNA profiles of cattle from Victoria (V...

journal_title：BMC genetics

authors： Srirattana K,McCosker K,Schatz T,St John JC

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:For anurans, knowledge of 5S rDNA is scarce. For Engystomops species, chromosomal homeologies are difficult to recognize due to the high level of inter- and intraspecific cytogenetic variation. In an attempt to better compare the karyotypes of the Amazonian species Engystomops freibergi and Engystomops peter...

journal_title：BMC genetics

authors： Rodrigues DS,Rivera M,Lourenço LB

更新日期：2012-03-20 00:00:00

abstract：BACKGROUND:Brachygnathia, cardiomegaly and renal hypoplasia syndrome (BCRHS, OMIA 001595-9940 ) is a previously reported recessively inherited disorder in Australian Poll Merino/Merino sheep. Affected lambs are stillborn with various congenital defects as reflected in the name of the disease, as well as short stature, ...

journal_title：BMC genetics

authors： Woolley SA,Hayes SE,Shariflou MR,Nicholas FW,Willet CE,O'Rourke BA,Tammen I

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Marek's disease (MD) is a highly neoplastic disease primarily affecting chickens, and remains as a chronic infectious disease that threatens the poultry industry. Copy number variation (CNV) has been examined in many species and is recognized as a major source of genetic variation that directly contributes t...

journal_title：BMC genetics

authors： Bai H,He Y,Ding Y,Chu Q,Lian L,Heifetz EM,Yang N,Cheng HH,Zhang H,Chen J,Song J

更新日期：2020-07-16 00:00:00

abstract：BACKGROUND:Approximately 90% of colorectal cancer (CRC) deaths are caused by tumors ability to migrate into the adjacent tissues and metastase into distant organs. More than 40 genes have been causally linked to the development of CRC but no mutations have been associated with metastasis yet. To identify molecular basi...

journal_title：BMC genetics

authors： Goryca K,Kulecka M,Paziewska A,Dabrowska M,Grzelak M,Skrzypczak M,Ginalski K,Mroz A,Rutkowski A,Paczkowska K,Mikula M,Ostrowski J

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:The establishment of the bisexual fertile fish hybrid lineage including the allodiploid and allotetraploid hybrids, from interspecific hybridization of red crucian carp (Carassius auratus red var. 2n = 100, 2n = AA) (♀) × common carp (Cyprinus carpio L. 2n = 100, 2n = BB) (♂), provided a good platform to inv...

journal_title：BMC genetics

authors： Zhang C,Ye L,Chen Y,Xiao J,Wu Y,Tao M,Xiao Y,Liu S

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:The current genetic structure of Iberian populations has presumably been affected by the complex orography of its territory, the different people and civilizations that settled there, its ancient and complex history, the diverse and persistent sociocultural patterns in its different regions, and also by the ...

journal_title：BMC genetics

authors： Calderón R,Lodeiro R,Varela TA,Fariña J,Ambrosio B,Guitard E,González-Martín A,Dugoujon JM

更新日期：2007-06-27 00:00:00

abstract：BACKGROUND:Tyrosinemia type I, the most severe disease of the tyrosine catabolic pathway is caused by a deficiency in fumarylacetoacetate hydrolase (FAH). A patient showing few of the symptoms associated with the disease, was found to be a compound heterozygote for a splice mutation, IVS6-1g->t, and a putative missense...

journal_title：BMC genetics

authors： Dreumont N,Poudrier JA,Bergeron A,Levy HL,Baklouti F,Tanguay RM

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Selection for grain yield under drought is an efficient criterion for improving the drought tolerance of rice. Recently, some drought-tolerant rice varieties have been developed using this selection criterion and successfully released for cultivation in drought-prone target environments. The process can be m...

journal_title：BMC genetics

authors： Mishra KK,Vikram P,Yadaw RB,Swamy BP,Dixit S,Cruz MT,Maturan P,Marker S,Kumar A

更新日期：2013-02-26 00:00:00

abstract：BACKGROUND:Overexploitation of wildlife populations results in direct consequences, such as extinction and local extirpation, as well as indirect effects including genetic diversity loss and changes in genetic structure. A clear understanding of the underlying genetic patterns of harvested species is necessary for sust...

journal_title：BMC genetics

authors： Dowell SA,de Buffrénil V,Kolokotronis SO,Hekkala ER

更新日期：2015-03-28 00:00:00

abstract：BACKGROUND:Root is the prime organ that sucks water and nutrients from deep layer of soil. Wild barley diversity exhibits remarkable variation in root system architecture that seems crucial in its adaptation to abiotic stresses like drought. In the present study, we performed quantitative trait locus (QTL) mapping of r...

journal_title：BMC genetics

authors： Naz AA,Arifuzzaman M,Muzammil S,Pillen K,Léon J

更新日期：2014-10-07 00:00:00

abstract：BACKGROUND:Meta-analysis is a popular methodology in several fields of medical research, including genetic association studies. However, the methods used for meta-analysis of association studies that report haplotypes have not been studied in detail. In this work, methods for performing meta-analysis of haplotype assoc...

journal_title：BMC genetics

authors： Bagos PG

更新日期：2011-01-19 00:00:00

abstract：BACKGROUND:Sitosterolemia is a recessively inherited disorder in humans that is associated with premature atherosclerotic disease. Mutations in ABCG5 or ABCG8, comprising the sitosterolemia locus, STSL, are now known to cause this disease. Three in-bred strains of rats, WKY, SHR and SHRSP, are known to be sitosterolemi...

journal_title：BMC genetics

authors： Chen J,Batta A,Zheng S,Fitzgibbon WR,Ullian ME,Yu H,Tso P,Salen G,Patel SB

更新日期：2005-07-18 00:00:00

abstract：BACKGROUND:Etl4(lacZ) (Enhancer trap locus 4) and Skt(Gt) (Sickle tail) are lacZ reporter gene integrations into the same locus on mouse chromosome 2 targeting a gene that is expressed in the notochord of early embryos and in multiple epithelia during later development. Both insertions caused recessive mutations that r...

journal_title：BMC genetics

authors： Serth K,Beckers A,Schuster-Gossler K,Pavlova MN,Müller J,Paul MC,Reinhardt R,Gossler A

更新日期：2015-12-18 00:00:00

abstract：BACKGROUND:The search to identify disease-susceptible genes requires access to biological material from numerous well-characterized subjects. Archived residual dried blood spot (DBS) samples, also known as Guthrie cards, from national newborn screening programs may provide a DNA source for entire populations. Combined ...

journal_title：BMC genetics

authors： Hollegaard MV,Grove J,Grauholm J,Kreiner-Møller E,Bønnelykke K,Nørgaard M,Benfield TL,Nørgaard-Pedersen B,Mortensen PB,Mors O,Sørensen HT,Harboe ZB,Børglum AD,Demontis D,Ørntoft TF,Bisgaard H,Hougaard DM

更新日期：2011-07-04 00:00:00

abstract：BACKGROUND:Yami and Ivatan islanders are Austronesian speakers from Orchid Island and the Batanes archipelago that are located between Taiwan and the Philippines. The paternal genealogies of the Yami tribe from 1962 monograph of Wei and Liu were compared with our dataset of non-recombining Y (NRY) chromosomes from the ...

journal_title：BMC genetics

authors： Loo JH,Trejaut JA,Yen JC,Chen ZS,Lee CL,Lin M

更新日期：2011-01-31 00:00:00

abstract：BACKGROUND:The transcription factor 7-like 2 (TCF7L2) gene is the most significant genetic risk factor for type 2 diabetes (T2D). Association analyses were performed on participants (n = 751, aged between 30 and 64) in the ISOR population-based study in the city of Oran. Dietary intakes were estimated using a weekly fo...

journal_title：BMC genetics

authors： Ouhaibi-Djellouli H,Mediene-Benchekor S,Lardjam-Hetraf SA,Hamani-Medjaoui I,Meroufel DN,Boulenouar H,Hermant X,Saidi-Mehtar N,Amouyel P,Houti L,Goumidi L,Meirhaeghe A

更新日期：2014-12-10 00:00:00

abstract：BACKGROUND:The aim of this study was to determine if variable number of tandem repeats (VNTR) in the second intron (STin2) of the serotonin transporter (SLC6A4) gene was associated with tobacco use disorder, successful smoking cessation, or smoking characteristics. In this case-control study, patients with current toba...

journal_title：BMC genetics

authors： Pizzo de Castro MR,Maes M,Guembarovski RL,Ariza CB,Reiche EM,Vargas HO,Vargas MM,de Melo LG,Dodd S,Berk M,Watanabe MA,Nunes SO

更新日期：2014-06-27 00:00:00

abstract：BACKGROUND:Associations between haplotypes and quantitative traits provide valuable information about the genetic basis of complex human diseases. Haplotypes also provide an effective way to deal with untyped SNPs. Two major challenges arise in haplotype-based association analysis of family data. First, haplotypes may ...

journal_title：BMC genetics

authors： Diao G,Lin DY

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:Egg production is the most economically-important trait in layers as it directly influences benefits of the poultry industry. To better understand the genetic architecture of egg production, we measured traits including age at first egg (AFE), weekly egg number (EN) from onset of laying eggs to 80 weeks whic...

journal_title：BMC genetics

authors： Liu Z,Yang N,Yan Y,Li G,Liu A,Wu G,Sun C

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:The Gpnmb gene encodes a transmembrane protein whose function(s) remain largely unknown. Here, we assess if a mutant allele of Gpnmb confers susceptibility to glaucoma by altering immune functions. DBA/2J mice have a mutant Gpnmb gene and they develop a form of glaucoma preceded by a pigment dispersing iris ...

journal_title：BMC genetics

authors： Anderson MG,Nair KS,Amonoo LA,Mehalow A,Trantow CM,Masli S,John SW

更新日期：2008-04-10 00:00:00

abstract：BACKGROUND:Female lions generally do not disperse far beyond their natal range, while males can disperse distances of over 200 km. However, in bush-like ecosystems dispersal distances less than 25 km are reported. Here, we investigate dispersal in lions sampled from the northern and southern extremes of Kruger National...

journal_title：BMC genetics

authors： van Hooft P,Keet DF,Brebner DK,Bastos ADS

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:Retinal function is ordered by interactions between transcriptional and posttranscriptional regulators at the molecular level. These regulators include transcription factors (TFs) and posttranscriptional factors such as microRNAs (miRs). Some studies propose that miRs predominantly target the TFs rather than...

journal_title：BMC genetics

authors： Andreeva K,Soliman MM,Cooper NG

更新日期：2015-04-24 00:00:00

abstract：BACKGROUND:Genetic maps characterizing the inheritance patterns of traits and markers have been developed for a wide range of species and used to study questions in biomedicine, agriculture, ecology and evolutionary biology. The status of rainbow trout genetic maps has progressed significantly over the last decade due ...

journal_title：BMC genetics

authors： Rexroad CE 3rd,Palti Y,Gahr SA,Vallejo RL

更新日期：2008-11-19 00:00:00