Abstract:
BACKGROUND:For anurans, knowledge of 5S rDNA is scarce. For Engystomops species, chromosomal homeologies are difficult to recognize due to the high level of inter- and intraspecific cytogenetic variation. In an attempt to better compare the karyotypes of the Amazonian species Engystomops freibergi and Engystomops petersi, and to extend the knowledge of 5S rDNA organization in anurans, the 5S rDNA sequences of Amazonian Engystomops species were isolated, characterized, and mapped. RESULTS:Two types of 5S rDNA, which were readily differentiated by their NTS (non-transcribed spacer) sizes and compositions, were isolated from specimens of E. freibergi from Brazil and E. petersi from two Ecuadorian localities (Puyo and Yasuní). In the E. freibergi karyotypes, the entire type I 5S rDNA repeating unit hybridized to the pericentromeric region of 3p, whereas the entire type II 5S rDNA repeating unit mapped to the distal region of 6q, suggesting a differential localization of these sequences. The type I NTS probe clearly detected the 3p pericentromeric region in the karyotypes of E. freibergi and E. petersi from Puyo and the 5p pericentromeric region in the karyotype of E. petersi from Yasuní, but no distal or interstitial signals were observed. Interestingly, this probe also detected many centromeric regions in the three karyotypes, suggesting the presence of a satellite DNA family derived from 5S rDNA. The type II NTS probe detected only distal 6q regions in the three karyotypes, corroborating the differential distribution of the two types of 5S rDNA. CONCLUSIONS:Because the 5S rDNA types found in Engystomops are related to those of Physalaemus with respect to their nucleotide sequences and chromosomal locations, their origin likely preceded the evolutionary divergence of these genera. In addition, our data indicated homeology between Chromosome 5 in E. petersi from Yasuní and Chromosomes 3 in E. freibergi and E. petersi from Puyo. In addition, the chromosomal location of the type II 5S rDNA corroborates the hypothesis that the Chromosomes 6 of E. petersi and E. freibergi are homeologous despite the great differences observed between the karyotypes of the Yasuní specimens and the others.
journal_name
BMC Genetjournal_title
BMC geneticsauthors
Rodrigues DS,Rivera M,Lourenço LBdoi
10.1186/1471-2156-13-17subject
Has Abstractpub_date
2012-03-20 00:00:00pages
17issn
1471-2156pii
1471-2156-13-17journal_volume
13pub_type
杂志文章相关文献
BMC GENETICS文献大全abstract:BACKGROUND:Although harness racing is of high economic importance to the global equine industry, significant genomic resources have yet to be applied to mapping harness racing success. To identify genomic regions associated with harness racing success, the current study performs genome-wide association analyses with th...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-018-0670-3
更新日期:2018-08-29 00:00:00
abstract:BACKGROUND:Despite several thousands of years of close contacts, there are genetic differences between the neighbouring countries of Finland and Sweden. Within Finland, signs of an east-west duality have been observed, whereas the population structure within Sweden has been suggested to be more subtle. With a fine-scal...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-9-54
更新日期:2008-08-19 00:00:00
abstract:BACKGROUND:Sudan is endowed with a variety of indigenous goat breeds which are used for meat and milk production and which are well adapted to the local environment. The aim of the present study was to determine the genetic diversity and relationship within and between the four main Sudanese breeds of Nubian, Desert, T...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-017-0553-z
更新日期:2017-10-23 00:00:00
abstract:BACKGROUND:Cell motility is an essential feature of the pathogenesis and morbidity of amoebiasis caused by Entamoeba histolytica. As motility depends on cytoskeletal organisation and regulation, a study of the molecular components involved is key to a better understanding of amoebic pathogenesis. However, little is kno...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-8-28
更新日期:2007-06-06 00:00:00
abstract:BACKGROUND:Infectious disease of livestock continues to be a cause of substantial economic loss and has adverse welfare consequences in both the developing and developed world. New solutions to control disease are needed and research focused on the genetic loci determining variation in immune-related traits has the pot...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-11-107
更新日期:2010-12-07 00:00:00
abstract:BACKGROUND:Despite the emergence of stereotactic body radiotherapy (SBRT) for treatment of medically inoperable early-stage non-small-cell lung cancer patients, the molecular effects of focal exposure of limited lung volumes to high-dose radiation have not been fully characterized. This study was designed to identify m...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-016-0338-9
更新日期:2016-01-27 00:00:00
abstract:BACKGROUND:Anopheles gambiae females are the world's most successful vectors of human malaria. However, a fraction of these mosquitoes is refractory to Plasmodium development. L3-5, a laboratory selected refractory strain, encapsulates transforming ookinetes/early oocysts of a wide variety of Plasmodium species. Previo...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-4-16
更新日期:2003-10-24 00:00:00
abstract:BACKGROUND:Cattle are bred for, amongst other factors, specific traits, including parasite resistance and adaptation to climate. However, the influence and inheritance of mitochondrial DNA (mtDNA) are not usually considered in breeding programmes. In this study, we analysed the mtDNA profiles of cattle from Victoria (V...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-017-0523-5
更新日期:2017-06-26 00:00:00
abstract:BACKGROUND:African Americans experience disproportionately higher prevalence of type 2 diabetes and related risk factors. Little research has been done on the association of ADIPOQ gene on type 2 diabetes, plasma adiponectin, blood glucose, HOMA-IR and body mass index (BMI) in African Americans. The objective of our re...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-015-0319-4
更新日期:2015-12-23 00:00:00
abstract::Only one genome scan to date has attempted to make use of the longitudinal data available in the Framingham Heart Study, and this attempt yielded evidence of linkage to a gene for mean systolic blood pressure. We show how the additional information available in these longitudinal data can be utilized to examine linkag...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-4-S1-S82
更新日期:2003-12-31 00:00:00
abstract:BACKGROUND:Recent advances in sequencing technologies have allowed for the retrieval of ancient DNA data (aDNA) from skeletal remains, providing direct genetic snapshots from diverse periods of human prehistory. Comparing samples taken in the same region but at different times, hereafter called "serial samples", may in...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-017-0575-6
更新日期:2017-12-15 00:00:00
abstract:BACKGROUND:DNA methylation is an epigenetic modification that mainly repress expression of genes essential during embryogenesis and development. There are key ATPase-dependent enzymes that read or write DNA methylation to remodel chromatin and regulate gene expression. Structural maintenance of chromosome hinge domain ...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-020-0809-x
更新日期:2020-01-15 00:00:00
abstract:BACKGROUND:Field pea (Pisum sativum L.) is among the prominent crops in the world as food and feed. There are relatively few simple sequence repeat (SSR) markers developed from expressed sequence tags (ESTs) in P. sativum. RESULTS:In the present study, 15 new EST-SSR markers were developed from publicly available ESTs...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-015-0261-5
更新日期:2015-08-19 00:00:00
abstract:BACKGROUND:Dyslexia is a polygenic speech and language disorder characterized by an unexpected difficulty in reading in children and adults despite normal intelligence and schooling. Increasing evidence reveals that different speech and language disorders could share common genetic factors. As previous study reported a...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-015-0172-5
更新日期:2015-02-03 00:00:00
abstract::Genotype data from the Illumina Linkage III SNP panel (n = 4,720 SNPs) and the Affymetrix 10 k mapping array (n = 11,120 SNPs) were used to test the effects of linkage disequilibrium (LD) between SNPs in a linkage analysis in the Collaborative Study on the Genetics of Alcoholism pedigree collection (143 pedigrees; 1,6...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-6-S1-S85
更新日期:2005-12-30 00:00:00
abstract:BACKGROUND:Hexaploid wheat (Triticum aestivum L.) possesses a large genome that contains 1.6 x 1010 bp of DNA. Isolation of a large number of gene sequences from complex gene families with a high level of gene sequence identity from genomic DNA is therefore difficult and time-consuming. Bacterial artificial chromosome ...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-8-18
更新日期:2007-05-04 00:00:00
abstract::Methods to handle missing data have been an area of statistical research for many years. Little has been done within the context of pedigree analysis. In this paper we present two methods for imputing missing data for polygenic models using family data. The imputation schemes take into account familial relationships a...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-4-S1-S42
更新日期:2003-12-31 00:00:00
abstract:BACKGROUND:The structure of haplogroup H reveals significant differences between the western and eastern edges of the Mediterranean, as well as between the northern and southern regions. Human populations along the westernmost Mediterranean coasts, which were settled by individuals from two continents separated by a re...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-017-0514-6
更新日期:2017-05-19 00:00:00
abstract:BACKGROUND:Brachygnathia, cardiomegaly and renal hypoplasia syndrome (BCRHS, OMIA 001595-9940 ) is a previously reported recessively inherited disorder in Australian Poll Merino/Merino sheep. Affected lambs are stillborn with various congenital defects as reflected in the name of the disease, as well as short stature, ...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-020-00913-8
更新日期:2020-09-15 00:00:00
abstract:BACKGROUND:Use of anti-hyperlipidemic medications compromises genetic analysis because of altered lipid profiles. We propose an empirical method to adjust lipid levels for medication effects so that the adjusted lipid values substitute the unmedicated lipid values in the genetic analysis. RESULTS:Published clinical tr...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-8-60
更新日期:2007-09-10 00:00:00
abstract:BACKGROUND:Fibroblast growth factor receptor 3 (FGFR3) is expressed in the growth plate of endochondral bones and serves as a negative regulator of linear bone elongation. Activating mutations severely limit bone growth, resulting in dwarfism, while inactivating mutations significantly enhance bone elongation and overa...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-9-67
更新日期:2008-10-21 00:00:00
abstract:BACKGROUND:Association mapping studies offer great promise to identify polymorphisms associated with phenotypes and for understanding the genetic basis of quantitative trait variation. To date, almost all association mapping studies based on structured plant populations examined the main effects of genetic factors on t...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-15-3
更新日期:2014-01-06 00:00:00
abstract:BACKGROUND:Linkage disequilibrium (LD) mapping is commonly used to evaluate markers for genome-wide association studies. Most types of LD software focus strictly on LD analysis and visualization, but lack supporting services for genotyping. RESULTS:We developed a freeware called LD2SNPing, which provides a complete pa...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-10-26
更新日期:2009-06-06 00:00:00
abstract:BACKGROUND:Cymbidium is a genus of 68 species in the orchid family, with extremely high ornamental value. Marker-assisted selection has proven to be an effective strategy in accelerating plant breeding for many plant species. Analysis of cymbidiums genetic background by molecular markers can be of great value in assist...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-014-0124-5
更新日期:2014-12-05 00:00:00
abstract:BACKGROUND:Cockerham genetic models are commonly used in quantitative trait loci (QTL) analysis with a special feature of partitioning genotypic variances into various genetic variance components, while the F(infinity) genetic models are widely used in genetic association studies. Over years, there have been some confu...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-10-52
更新日期:2009-09-04 00:00:00
abstract::Following publication of the original article [1], the authors reported the need for a more detailed acknowledgement of the source of the samples that were analyzed and their coordinates, which are discussed in the 'Methods' section of the article. This Correction provides an addition to the 'Methods' section, and a s...
journal_title:BMC genetics
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12863-018-0632-9
更新日期:2018-07-12 00:00:00
abstract:BACKGROUND:Structured association mapping is proving to be a powerful strategy to find genetic polymorphisms associated with disease. However, these algorithms are often distributed as command line implementations that require expertise and effort to customize and put into practice. Because of the difficulty required t...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/1471-2156-13-24
更新日期:2012-04-03 00:00:00
abstract:BACKGROUND:Studies on genetic effects of coffee consumption are scarce for Asian populations. We conducted a genome-wide association study (GWAS) of habitual coffee consumption in Japan using a self-reporting online survey. RESULTS:Candidate genetic loci associated with habitual coffee consumption were searched within...
journal_title:BMC genetics
pub_type: 杂志文章,meta分析
doi:10.1186/s12863-019-0763-7
更新日期:2019-07-26 00:00:00
abstract:BACKGROUND:The SnRKs (sucrose non-fermenting 1 related protein kinase) are a gene family coding for Ser/Thr protein kinases and play important roles in linking the tolerance and metabolic responses of plants to abiotic stresses. To date, no genome-wide characterization of the sucrose non-ferment 1 related protein kinas...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-017-0506-6
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND:Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently requires the identification of the respective phenotypic trait of interest and is simply based on a significant difference between a consomic and host strain...
journal_title:BMC genetics
pub_type: 杂志文章
doi:10.1186/s12863-016-0411-4
更新日期:2016-06-29 00:00:00