Wild barley introgression lines revealed novel QTL alleles for root and related shoot traits in the cultivated barley (Hordeum vulgare L.).

abstract：BACKGROUND:The high mobility group A1 proteins (HMGA1a/HMGA1b) are highly conserved between mammalian species and widely described as participating in various cellular processes. By inducing DNA conformation changes the HMGA1 proteins indirectly influence the binding of various transcription factors and therefore effec...

journal_title：BMC genetics

authors： Beuing C,Soller JT,Muth M,Wagner S,Dolf G,Schelling C,Richter A,Willenbrock S,Reimann-Berg N,Winkler S,Nolte I,Bullerdiek J,Murua Escobar H

更新日期：2008-07-23 00:00:00

abstract：BACKGROUND:Hexaploid wheat (Triticum aestivum L.) possesses a large genome that contains 1.6 x 1010 bp of DNA. Isolation of a large number of gene sequences from complex gene families with a high level of gene sequence identity from genomic DNA is therefore difficult and time-consuming. Bacterial artificial chromosome ...

journal_title：BMC genetics

authors： Huang XQ,Cloutier S

更新日期：2007-05-04 00:00:00

abstract：BACKGROUND:RNA sequencing (RNA-seq) technology has identified multiple differentially expressed (DE) genes associated to complex disease, however, these genes only explain a modest part of variance. Omnigenic model assumes that disease may be driven by genes with indirect relevance to disease and be propagated by funct...

journal_title：BMC genetics

authors： Shao F,Wang Y,Zhao Y,Yang S

更新日期：2019-03-19 00:00:00

abstract：BACKGROUND:Population stratification can cause spurious associations in a genome-wide association study (GWAS), and occurs when differences in allele frequencies of single nucleotide polymorphisms (SNPs) are due to ancestral differences between cases and controls rather than the trait of interest. Principal components ...

journal_title：BMC genetics

authors： Solovieff N,Hartley SW,Baldwin CT,Perls TT,Steinberg MH,Sebastiani P

更新日期：2010-12-09 00:00:00

abstract：:This study, part of the Genetic Analysis Workshop 14 (GAW14), explored real Collaborative Study on the Genetics of Alcoholism data for linkage and association mapping between genetic polymorphisms (microsatellite and single-nucleotide polymorphisms (SNPs)) and beta (16.5-20 Hz) oscillations of the brain rhythms (ecb21...

journal_title：BMC genetics

authors： Kraja AT,Borecki IB,Province MA

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:Despite several thousands of years of close contacts, there are genetic differences between the neighbouring countries of Finland and Sweden. Within Finland, signs of an east-west duality have been observed, whereas the population structure within Sweden has been suggested to be more subtle. With a fine-scal...

journal_title：BMC genetics

authors： Hannelius U,Salmela E,Lappalainen T,Guillot G,Lindgren CM,von Döbeln U,Lahermo P,Kere J

更新日期：2008-08-19 00:00:00

abstract：:Three variants of the confidence set inference (CSI) procedure were proposed and applied to both the simulated and the Collaborative Study on the Genetics of Alcoholism (COGA) data. For each of the two applications, we first performed a preliminary genome scan study based on the microsatellite markers using the GENEHU...

journal_title：BMC genetics

authors： Papachristou C,Lin S

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:Although genome-wide association studies have successfully identified thousands of variants associated to complex traits, these variants only explain a small amount of the entire heritability of the trait. Gene-gene interactions have been proposed as a source to explain a significant percentage of the missin...

journal_title：BMC genetics

authors： Aschard H,Gusev A,Brown R,Pasaniuc B

更新日期：2015-10-24 00:00:00

abstract：BACKGROUND:Arterial stiffness is an independent predictor of cardiovascular outcomes in hypertensive patients including myocardial infarction, fatal stroke, cerebral micro-bleeds which predicts cerebral hemorrhage in hypertensive patients, as well as progression to hypertension in non-hypertensive subjects. The associa...

journal_title：BMC genetics

authors： Decano JL,Pasion KA,Black N,Giordano NJ,Herrera VL,Ruiz-Opazo N

更新日期：2016-01-11 00:00:00

abstract：BACKGROUND:Studies on genetic effects of coffee consumption are scarce for Asian populations. We conducted a genome-wide association study (GWAS) of habitual coffee consumption in Japan using a self-reporting online survey. RESULTS:Candidate genetic loci associated with habitual coffee consumption were searched within...

journal_title：BMC genetics

authors： Jia H,Nogawa S,Kawafune K,Hachiya T,Takahashi S,Igarashi M,Saito K,Kato H

更新日期：2019-07-26 00:00:00

abstract：BACKGROUND:Linkage maps are essential tools for the study of several topics in genome biology. High density linkage maps for the porcine autosomes have been constructed exploiting the high density data provided by the PorcineSNP60 BeadChip. However, a high density SSCX linkage map has not been reported up to date. The ...

journal_title：BMC genetics

authors： Fernández AI,Muñoz M,Alves E,Folch JM,Noguera JL,Enciso MP,Rodríguez Mdel C,Silió L

更新日期：2014-12-20 00:00:00

abstract：BACKGROUND:Transgenic poplar (Populus × euramericana 'Guariento') plants harboring five exogenous, stress-related genes exhibit increased tolerance to multiple stresses including drought, salt, waterlogging, and insect feeding, but the complex mechanisms underlying stress tolerance in these plants have not been elucida...

journal_title：BMC genetics

authors： Zhang W,Chu Y,Ding C,Zhang B,Huang Q,Hu Z,Huang R,Tian Y,Su X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:India is home to many ethnically and linguistically diverse populations. It is hypothesized that history of invasions by people from Persia and Central Asia, who are referred as Aryans in Hindu Holy Scriptures, had a defining role in shaping the Indian population canvas. A shift in spoken languages from Drav...

journal_title：BMC genetics

authors： Ali M,Liu X,Pillai EN,Chen P,Khor CC,Ong RT,Teo YY

更新日期：2014-07-22 00:00:00

abstract：BACKGROUND:Cell motility is an essential feature of the pathogenesis and morbidity of amoebiasis caused by Entamoeba histolytica. As motility depends on cytoskeletal organisation and regulation, a study of the molecular components involved is key to a better understanding of amoebic pathogenesis. However, little is kno...

journal_title：BMC genetics

authors： Zaki M,King J,Fütterer K,Insall RH

更新日期：2007-06-06 00:00:00

abstract：BACKGROUND:Sudan is endowed with a variety of indigenous goat breeds which are used for meat and milk production and which are well adapted to the local environment. The aim of the present study was to determine the genetic diversity and relationship within and between the four main Sudanese breeds of Nubian, Desert, T...

journal_title：BMC genetics

authors： Rahmatalla SA,Arends D,Reissmann M,Said Ahmed A,Wimmers K,Reyer H,Brockmann GA

更新日期：2017-10-23 00:00:00

abstract：BACKGROUND:Sox domain containing genes are important metazoan transcriptional regulators implicated in a wide rage of developmental processes. The vertebrate B subgroup contains the Sox1, Sox2 and Sox3 genes that have early functions in neural development. Previous studies show that Drosophila Group B genes have been f...

journal_title：BMC genetics

authors： McKimmie C,Woerfel G,Russell S

更新日期：2005-05-19 00:00:00

abstract：BACKGROUND:Cymbidium is a genus of 68 species in the orchid family, with extremely high ornamental value. Marker-assisted selection has proven to be an effective strategy in accelerating plant breeding for many plant species. Analysis of cymbidiums genetic background by molecular markers can be of great value in assist...

journal_title：BMC genetics

authors： Li X,Jin F,Jin L,Jackson A,Huang C,Li K,Shu X

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:In mice MEOX2/TCF15 heterodimers are highly expressed in heart endothelial cells and are involved in the transcriptional regulation of lipid transport. In a general population, we investigated whether genetic variation in these genes predicted coronary heart disease (CHD). RESULTS:In 2027 participants rando...

journal_title：BMC genetics

authors： Yang WY,Petit T,Thijs L,Zhang ZY,Jacobs L,Hara A,Wei FF,Salvi E,Citterio L,Delli Carpini S,Gu YM,Knez J,Cauwenberghs N,Barcella M,Barlassina C,Manunta P,Coppiello G,Aranguren XL,Kuznetsova T,Cusi D,Verhamme P,Lu

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Previous investigations have highlighted the importance of genetic variation in the determination of bitter tasting ability, however have left unaddressed questions as to within group variation in tasting ability or the possibility of genetic prescription of intermediate tasting ability. Our aim was to exami...

journal_title：BMC genetics

authors： Timpson NJ,Heron J,Day IN,Ring SM,Bartoshuk LM,Horwood J,Emmett P,Davey-Smith G

更新日期：2007-07-28 00:00:00

abstract：BACKGROUND:Genetic maps characterizing the inheritance patterns of traits and markers have been developed for a wide range of species and used to study questions in biomedicine, agriculture, ecology and evolutionary biology. The status of rainbow trout genetic maps has progressed significantly over the last decade due ...

journal_title：BMC genetics

authors： Rexroad CE 3rd,Palti Y,Gahr SA,Vallejo RL

更新日期：2008-11-19 00:00:00

abstract：BACKGROUND:Genomic selection exploits dense genome-wide marker data to predict breeding values. In this study we used a large sugar beet population of 924 lines representing different germplasm types present in breeding populations: unselected segregating families and diverse lines from more advanced stages of selectio...

journal_title：BMC genetics

authors： Würschum T,Reif JC,Kraft T,Janssen G,Zhao Y

更新日期：2013-09-18 00:00:00

abstract：BACKGROUND:Use of anti-hyperlipidemic medications compromises genetic analysis because of altered lipid profiles. We propose an empirical method to adjust lipid levels for medication effects so that the adjusted lipid values substitute the unmedicated lipid values in the genetic analysis. RESULTS:Published clinical tr...

journal_title：BMC genetics

authors： Wu J,Province MA,Coon H,Hunt SC,Eckfeldt JH,Arnett DK,Heiss G,Lewis CE,Ellison RC,Rao DC,Rice T,Kraja AT

更新日期：2007-09-10 00:00:00

abstract：BACKGROUND:Female lions generally do not disperse far beyond their natal range, while males can disperse distances of over 200 km. However, in bush-like ecosystems dispersal distances less than 25 km are reported. Here, we investigate dispersal in lions sampled from the northern and southern extremes of Kruger National...

journal_title：BMC genetics

authors： van Hooft P,Keet DF,Brebner DK,Bastos ADS

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:Yami and Ivatan islanders are Austronesian speakers from Orchid Island and the Batanes archipelago that are located between Taiwan and the Philippines. The paternal genealogies of the Yami tribe from 1962 monograph of Wei and Liu were compared with our dataset of non-recombining Y (NRY) chromosomes from the ...

journal_title：BMC genetics

authors： Loo JH,Trejaut JA,Yen JC,Chen ZS,Lee CL,Lin M

更新日期：2011-01-31 00:00:00

abstract：BACKGROUND:The structure of haplogroup H reveals significant differences between the western and eastern edges of the Mediterranean, as well as between the northern and southern regions. Human populations along the westernmost Mediterranean coasts, which were settled by individuals from two continents separated by a re...

journal_title：BMC genetics

authors： Hernández CL,Dugoujon JM,Novelletto A,Rodríguez JN,Cuesta P,Calderón R

更新日期：2017-05-19 00:00:00

abstract：BACKGROUND:Genomic information can be used to predict not only continuous but also categorical (e.g. binomial) traits. Several traits of interest in human medicine and agriculture present a discrete distribution of phenotypes (e.g. disease status). Root vigor in sugar beet (B. vulgaris) is an example of binomial trait ...

journal_title：BMC genetics

authors： Biscarini F,Stevanato P,Broccanello C,Stella A,Saccomani M

更新日期：2014-07-22 00:00:00

abstract：BACKGROUND:Stripe rust is a serious fungal disease of wheat (Triticum aestivum L.) caused by Puccinia striiformis f. sp. tritici (Pst), which results in yield reduction and decreased grain quality. Breeding for genetic resistance to stripe rust is the most cost-effective method to control the disease. In the present st...

journal_title：BMC genetics

authors： Yao F,Zhang X,Ye X,Li J,Long L,Yu C,Li J,Wang Y,Wu Y,Wang J,Jiang Q,Li W,Ma J,Wei Y,Zheng Y,Chen G

更新日期：2019-03-26 00:00:00

abstract：BACKGROUND:Grasslands in the Arctic tundra undergo irreversible degradation due to climatic changes and also over-exploitation and depletion of scarce resources. Comprehensive investigations of cytogenomic structures of valuable Arctic and sub-Arctic grassland species is essential for clarifying their genetic peculiari...

journal_title：BMC genetics

authors： Amosova AV,Zoshchuk SA,Rodionov AV,Ghukasyan L,Samatadze TE,Punina EO,Loskutov IG,Yurkevich OY,Muravenko OV

更新日期：2019-12-04 00:00:00

abstract：:The purpose of these analyses was to determine if incorporating or adjusting for covariates in genetic analyses helped or hindered in genetic analyses, specifically heritability and linkage analyses. To study this question, two types of covariate models were used in the simulated Genetic Analysis Workshop 14 dataset i...

journal_title：BMC genetics

authors： Bailey JN

更新日期：2005-12-30 00:00:00

abstract：BACKGROUND:We propose a gene-level association test that accounts for individual relatedness and population structures in pedigree data in the framework of linear mixed models (LMMs). Our method data-adaptively combines the results across a class of score-based tests, only requiring fitting a single null model (under t...

journal_title：BMC genetics

authors： Park JY,Wu C,Pan W

更新日期：2018-09-17 00:00:00