Determination of ring- and N-substituted amphetamines as heptafluorobutyryl derivatives.

Abstract:

:An improved derivatization method for analysing 12 ring- and N-substituted amphetamine-derivatives in body fluids or seized materials by gas chromatograph combined either with mass spectrometer, electron capture or nitrogen phosphorus detector is presented. Heptafluorobutyric anhydride is used as derivatization reagent. No heating or standing period is needed in this procedure. Most of the drugs considered were distinguishable from each other according to their retention times and all of them according to their EI mass spectra. The base peak or one of the most intense peaks in the mass spectra contained benzyl radical and the m/e values were different according to the substituent.

journal_name

Forensic Sci Int

authors

Lillsunde P,Korte T

doi

10.1016/0379-0738(91)90081-s

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

205-13

issue

2

eissn

0379-0738

issn

1872-6283

pii

0379-0738(91)90081-S

journal_volume

49

pub_type

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