Abstract:
:During goal-directed movements, primates are able to rapidly and accurately control an online trajectory despite substantial delay times incurred in the sensorimotor control loop. To address the problem of large delays, it has been proposed that the brain uses an internal forward model of the arm to estimate current and upcoming states of a movement, which are more useful for rapid online control. To study online control mechanisms in the posterior parietal cortex (PPC), we recorded from single neurons while monkeys performed a joystick task. Neurons encoded the static target direction and the dynamic movement angle of the cursor. The dynamic encoding properties of many movement angle neurons reflected a forward estimate of the state of the cursor that is neither directly available from passive sensory feedback nor compatible with outgoing motor commands and is consistent with PPC serving as a forward model for online sensorimotor control. In addition, we found that the space-time tuning functions of these neurons were largely separable in the angle-time plane, suggesting that they mostly encode straight and approximately instantaneous trajectories.
journal_name
Proc Natl Acad Sci U S Aauthors
Mulliken GH,Musallam S,Andersen RAdoi
10.1073/pnas.0802602105subject
Has Abstractpub_date
2008-06-17 00:00:00pages
8170-7issue
24eissn
0027-8424issn
1091-6490pii
0802602105journal_volume
105pub_type
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