Synthesis and assembly of self-complementary calix[4]arenes.

Abstract:

:A calix[4]arene was designed to reversibly dimerize and form an egg-shaped enclosure. Adhesive interactions in the assembly were provided by four self-associating ureas, which form a cyclic array containing 16 hydrogen bonds. The synthesis was completed in four steps from the previously described O,O',O",O"'-tetrabenzylcalix[4]arene. Evidence for dimerization of the calixarene tetraurea was provided by H NMR, mass spectrometry, and the observation of encapsulated molecules. The resulting cavity was of sufficient size to capture guests such as ethyl benzene and p-xylene.

authors

Shimizu KD,Rebek J Jr

doi

10.1073/pnas.92.26.12403

subject

Has Abstract

pub_date

1995-12-19 00:00:00

pages

12403-7

issue

26

eissn

0027-8424

issn

1091-6490

journal_volume

92

pub_type

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