Characterization of sirolimus metabolites in pediatric solid organ transplant recipients.

abstract：UNLABELLED:The Latin American Pediatric Nephrology Association (ALANEPE) reports the first regional kidney transplant registry in Latin America. A mean range of 75%, 30% to 100% renal transplant recipients under 21 yr old were included. Out of 20 countries invited to participate, 14 performed renal transplant, 11 had u...

journal_title：Pediatric transplantation

authors： Latin American Pediatric Nephrology Association.,Latin American Pediatric Renal Transplant Cooperative Study.

更新日期：2010-09-01 00:00:00

abstract：:We studied restoration of the coagulation and fibrinolysis system in pediatric patients following liver transplantation and biomarkers of blood coagulation and fibrinolysis for suspecting the occurrence of acute cellular rejection. Coagulation activity recovered rapidly within two days following transplantation, but i...

journal_title：Pediatric transplantation

authors： Mimuro J,Mizuta K,Kawano Y,Hishikawa S,Hamano A,Kashiwakura Y,Ishiwata A,Ohmori T,Madoiwa S,Kawarasaki H,Sakata Y

更新日期：2010-05-01 00:00:00

abstract：:Investigations of HCT for refractory JIA have employed high dose immunosuppressive drugs, such as CY and ATG with or without low dose TBI. Initial disease response has been observed in approximately two-thirds of patients; however, relapse occurs in about half of the responders. The current report describes a regimen ...

journal_title：Pediatric transplantation

authors： Woolfrey A,Storek J,Bowyer S,Nelson R,Robertson M,Wallace C

更新日期：2010-09-01 00:00:00

abstract：:IHHE as the most common vascular tumor of the liver in infancy can present with acute postnatal liver and congestive heart failure. LTx may be a lifesaving option, but can be complicated by extrahepatic involvement and bleeding complications, especially in neonates. Here we discuss the benefit of LTx in cases of acute...

journal_title：Pediatric transplantation

authors： Grabhorn E,Richter A,Fischer L,Krebs-Schmitt D,Ganschow R

更新日期：2009-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) infections are known to have a more benign course in children than in adults. Although the natural history of HCV recurrence after liver transplantation has been well studied in adult patients, much less is known about HCV recurrence after liver transplantation in pediatric patients. Herein, we...

journal_title：Pediatric transplantation

authors： Udell IW,Barshes NR,Finegold MJ,Lee TC,Scott JD,Carter B,Karpen S,Goss JA

更新日期：2006-08-01 00:00:00

abstract：:Administration of hematopoietic growth factors, with or without chemotherapy, can augment progenitor cell numbers available for collection. The dose of granulocyte colony stimulating factor (G-CSF) used for mobilization of peripheral blood progenitor cells (PBPC) is controversial, and doses between 5 and 32 microg/kg/...

journal_title：Pediatric transplantation

authors： Kurekci AE,Kiss JE,Koehler M

更新日期：1998-05-01 00:00:00

abstract：:Small bowel transplantation has become a life-saving procedure for selected adults and children with intestinal failure who are intolerant to parental nutrition. There are few pediatric data available on the results of this procedure. In this article we review the background of intestinal transplantation, present the ...

journal_title：Pediatric transplantation

authors： Atkison P,Chatzipetrou M,Tsaroucha A,Lehmann R,Tzakis A,Grant D

更新日期：1997-11-01 00:00:00

abstract：:We report a case of EBV encephalitis in a seven-yr-old child with Ph+ ALL. Two months after an allogeneic HSCT from his HLA mismatched mother, the patient showed an altered sensorium, generalized seizures, and a left hemiparesis. Brain MRI demonstrated multiple lesions highly suggestive for viral encephalitis. Blood a...

journal_title：Pediatric transplantation

authors： Barberi W,Perrone S,Iori AP,Torelli GF,Testi AM,Moleti ML,Ceglie T,Papoff P,Caresta E,Antonelli M,Gianno F,Melone A,Badiali M,Giangaspero F,Foà R,Gentile G

更新日期：2015-02-01 00:00:00

abstract：:The clinical utility of tacrolimus monitoring in adults has been well documented. The present study compared tacrolimus monitoring in a pediatric population of 34 liver transplant patients in four US centers with an adult population of 111 patients in six US centers. Subjects (adult and pediatric) were evaluated, at d...

journal_title：Pediatric transplantation

authors： MacFarlane GD,Venkataramanan R,McDiarmid SV,Pirsch JD,Scheller DG,Ersfeld DL,Fitzsimmons WE

更新日期：2001-04-01 00:00:00

abstract：:Little has been studied regarding the diets of children following LTX. The study aim was to assess and compare dietary intake and DQ of healthy children and children post-LTX. Children and adolescents (2-18 years) post-LTX (n=27) and healthy children (n=28) were studied. Anthropometric and demographic data and two 24-...

journal_title：Pediatric transplantation

authors： Alzaben AS,MacDonald K,Robert C,Haqq A,Gilmour SM,Yap J,Mager DR

更新日期：2017-09-01 00:00:00

abstract：:Biliary atresia is defined as partial or total obliteration of the extra-hepatic bile ducts. In advanced cases, liver transplantation (LTx) is considered the most appropriate treatment. This report describes a female patient whose biliary atresia and subsequent cirrhosis required LTx at 1 yr of age. Macroscopic inspec...

journal_title：Pediatric transplantation

authors： Bilezikçi B,Demirhan B,Kiyici H,Haberal M

更新日期：2001-02-01 00:00:00

abstract：:This study reports the clinical complication and infection rates of an active pediatric IT program that has never utilized bowel decontamination in either the donor or the recipient. All patients undergoing IT from 2003 to 2015 at a single pediatric IT center were reviewed. Post-transplant surgical, infectious, and im...

journal_title：Pediatric transplantation

authors： Clouse JW,Kubal CA,Fridell JA,Mangus RS

更新日期：2018-05-01 00:00:00

abstract：:Renal transplantation is the treatment of choice for children with ESRD offering advantages of improved survival, growth potential, cognitive development, and quality of life. The aim of our study was to compare the outcomes of LDKT vs DDKT performed in children at a single center. Retrospective chart review of pediat...

journal_title：Pediatric transplantation

authors： Pérez-Bertólez S,Barrero R,Fijo J,Alonso V,Ojha D,Fernández-Hurtado MÁ,Martínez J,León E,García-Merino F

更新日期：2017-05-01 00:00:00

abstract：:Many pediatric centers utilize a variety of protocols including preemptive plasmapheresis to prevent the recurrence of FSGS post-transplant. But the effectiveness of this expensive, time-consuming process of plasmapheresis in the prevention of FSGS recurrence is still unclear. We retrospectively reviewed all pediatric...

journal_title：Pediatric transplantation

authors： Verghese PS,Rheault MN,Jackson S,Matas AJ,Chinnakotla S,Chavers B

更新日期：2018-05-01 00:00:00

abstract：:Although it is known that children undergoing heart transplantation are at increased risk for both AKI and CKD, renal function following CHLT remains understudied. All pediatric CHLT patients from 2006 to 2019 were included. The prevalence of AKI in the first 7 post-operative days, renal recovery at 30 post-operative ...

journal_title：Pediatric transplantation

authors： Lee A,Concepcion W,Gonzales S,Sutherland SM,Hollander SA

更新日期：2020-11-01 00:00:00

abstract：:Several studies suggested that the incidence of new-onset diabetes following pediatric kidney transplantation has increased markedly in recent years, with reported incidence of up to 20%. However, limited information is available regarding the incidence and features of pretransplant status of abnormal glucose toleranc...

journal_title：Pediatric transplantation

authors： Shishido S,Sato H,Asanuma H,Shindo M,Hataya H,Ishikura K,Hamasaki Y,Goto M,Ikeda M,Honda M

更新日期：2006-02-01 00:00:00

abstract：:Total body irradiation and high-dose chemotherapy, applied as a preparatory regimen for bone marrow transplantation (BMT) in children with acute lymphoblastic leukemia (ALL), are particularly hazardous to the gonads and, in addition, can impair hypothalamo pituitary-gonadal control. Longitudinal data on pubertal devel...

journal_title：Pediatric transplantation

authors： Mayer EI,Dopfer RE,Klingebiel T,Scheel-Walter H,Ranke MB,Niethammer D

更新日期：1999-02-01 00:00:00

abstract：:Prematurity and very low birthweight have often been considered relative contraindications to neonatal organ donation. Organ procurement from neonatal donors is further complicated by unclear guidelines regarding neonatal brain death. We report a successful case of multivisceral transplantation using a graft from a 10...

journal_title：Pediatric transplantation

authors： Cauley RP,Suh MY,Kamin DS,Lillehei CW,Jenkins RL,Jonas MM,Vakili K,Kim HB

更新日期：2012-12-01 00:00:00

abstract：:Acute graft-versus-host disease (GVHD) is a common and serious complication of allogeneic blood and marrow transplantation. Acute GVHD is commonly graded according to modified Glucksberg criteria. There is considerable within-grade heterogeneity with different patterns of skin, liver, or gut involvement. In this comme...

journal_title：Pediatric transplantation

authors： Goyal RK,Goyal M,Sankaranarayan K

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:In adults, the time of day for LT does not affect post-transplant outcomes. Whether this is true or not in children is unknown. In this study, we aimed to evaluate if weekend and weeknight liver transplants are associated with worse patient and graft survival in children. METHODS:We interrogated the UNOS da...

journal_title：Pediatric transplantation

authors： Rogers ME,Egberg MD,Sylvester F,Lichtman S,Lin FC

更新日期：2020-12-01 00:00:00

abstract：:Acute liver failure (ALF) is a rare but often fatal disorder in childhood. Its aetiology includes infections, toxins, metabolic disorders, infiltrative diseases, autoimmune hepatitis, ischaemia, irradiation damage, but in a high proportion of cases it remains unknown. In contrast to adults, in children with ALF hepati...

journal_title：Pediatric transplantation

authors： Dhawan A,Cheeseman P,Mieli-Vergani G

更新日期：2004-12-01 00:00:00

abstract：:Adolescence is a difficult time for transplant recipients, who need to cope with the challenges of becoming independent from their parents, as well as taking responsibility for their own behavior and medication. They need to balance their developing sexuality with a body image which may be affected by the side-effects...

journal_title：Pediatric transplantation

authors： Kelly DA

更新日期：2002-12-01 00:00:00

abstract：:During the past 50 yr, intensive studies into the use of hematopoietic cell transplantation (HCT) for therapy of cancer and non-malignant hematologic diseases have changed this treatment modality from one that was thought to be plagued by insurmountable complications to one that is now standard therapy for some diseas...

journal_title：Pediatric transplantation

authors： Storb R

更新日期：2004-06-01 00:00:00

abstract：:ADV is frequently seen in our pediatric SOT population. It presents in a variety of clinical presentation and can cause severe disease. In this population, there are very few studies to determine the safety of CDV as a potential therapeutic agent. We present the findings of our retrospective study evaluating the effic...

journal_title：Pediatric transplantation

authors： Guerra Sanchez CH,Lorica CD,Arheart KL,Perez MM,Tekin A,Gonzalez IA

更新日期：2018-06-03 00:00:00

abstract：:To date, the evidence upon which a decision is made to transplant a child with acute lymphoblastic leukaemia either in first or subsequent remission has rarely been based on randomized trial data. Modern era management of infection and graft-versus-host disease lessens risks but procedure-related deaths still remain h...

journal_title：Pediatric transplantation

authors： Eden OB

更新日期：1999-01-01 00:00:00

abstract：:We sought to examine the relationship between liver transplant-related total cost, patient outcome, and hospital resource utilization at freestanding children's hospitals. Using the PHIS database, a retrospective study of 374 patients that underwent liver transplantation at 15 freestanding children's hospitals from Ju...

journal_title：Pediatric transplantation

authors： Minneman JA,Grijalva JL,LaQuaglia MJ,Kim HB,Rangel SJ,Vakili K

更新日期：2016-11-01 00:00:00

abstract：:There are little data on prevalence of dyslipidemia in pediatric kidney TX recipients in the modern IS era. LP profiles of 38 TX recipients receiving triple IS with MMF, prednisone, and tacrolimus were compared with those of 11 children on HD using mixed model multiple linear regression analysis of repeated measures a...

journal_title：Pediatric transplantation

authors： Sgambat K,He J,McCarter RJ,Moudgil A

更新日期：2008-11-01 00:00:00

abstract：:Depression is common in pediatric chronic kidney disease (CKD) patients. Depression is associated with inferior long-term outcomes. There is a paucity of studies that evaluate depression and possible associated factors in children and adolescents requiring renal replacement therapy (RRT). Cross-sectional study using C...

journal_title：Pediatric transplantation

authors： Rodriguez Cuellar CI,García de la Puente S,Hernández Moraria J,Bojórquez Ochoa A,Filler G,Zaltzman Grishevich S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:ILNEB constitute an autosomal recessive disorder caused by homozygous or compound heterozygous mutation of the gene for the ITGA3. To date, 8 ILNEB patients have been reported, but all 6 neonatal-onset ILNEB patients suffered early death within 2 years. The most common cause of death among previously reporte...

journal_title：Pediatric transplantation

authors： Okamoto T,Nakamura A,Hayashi A,Yamaguchi T,Ogawa Y,Natsuga K,Yanagi K,Hotta K

更新日期：2021-01-20 00:00:00

abstract：:Liver transplant is a treatment option for patients with MMA-emia. While this therapy does not bring about a complete cure, it is expected to prolong survival and improve the QOL of patients. The aim of this study was to evaluate the significance of LDLT for patients with MMA-emia in Japan. Clinical information on 13 ...

journal_title：Pediatric transplantation

authors： Sakamoto R,Nakamura K,Kido J,Matsumoto S,Mitsubuchi H,Inomata Y,Endo F

更新日期：2016-12-01 00:00:00