Optimal immunosuppression in teenagers.

abstract：:Success after solid organ transplantation is dependent on the proper balance of immunosuppression to prevent rejection of the allograft while limiting the risk of developing infections and malignancy. We present a 9-year-old girl, remote from transplant, who presented with airway plaque after a change in immunosuppres...

journal_title：Pediatric transplantation

authors： Ryan TD,Absalon MJ,de Alarcon A,Gupta A,Peters AL,Lorts A,Danziger-Isakov LA,Chin C

更新日期：2017-11-01 00:00:00

abstract：:Rejection remains a major threat in pediatric renal transplantation (Tx), causing graft failure and increased exposure to drugs. The new chimeric antibody, basiliximab, directed against the alpha-chain of the interleukin-2 receptor (IL-2R), has been shown to be effective in preventing rejection episodes in adult renal...

journal_title：Pediatric transplantation

authors： Vester U,Kranz B,Testa G,Malagò M,Beelen D,Broelsch CE,Hoyer PF

更新日期：2001-08-01 00:00:00

abstract：:MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

journal_title：Pediatric transplantation

authors： Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:Medical cannabis is now legal in over half of the United States. As more patients adopt this unconventional therapy, it is inevitable that potential transplant recipients will disclose their cannabis use during transplant evaluation. Transplant teams are tasked with the decision to utilize a pressure resource, often w...

journal_title：Pediatric transplantation

authors： Ryan JE,Noeder M,Burke C,Stubblefield SC,Sulieman S,Miller EG

更新日期：2019-08-01 00:00:00

abstract：:INFVA is an important cause of pulmonary infections in patients receiving BMT, and is associated with considerable morbidity and mortality for a readily preventable and treatable infection. Few studies have addressed the impact of the new neuraminidase inhibitors in the prognosis of influenza after BMT. The aim of thi...

journal_title：Pediatric transplantation

authors： Mellouli F,Ouederni M,Dhouib N,Hajkacem MA,Slim A,Bejaoui M

更新日期：2010-03-01 00:00:00

abstract：:Delayed recovery of thrombocytopenia is a well-known complication after allogeneic HSCT. Eltrombopag (ELT), a thrombopoietin receptor agonist (TRAs), induces platelet maturation and release. Mostly conducted in adults, some of the previous studies have shown that ELT seems to enhance platelet recovery for post-allogen...

journal_title：Pediatric transplantation

authors： Yaman Y,Elli M,Şahin Ş,Özdilli K,Bilgen H,Bayram N,Nepesov S,Anak S

更新日期：2021-01-16 00:00:00

abstract：:Studies are increasingly recognizing health-related quality of life (HRQOL) as a key pediatric outcome in both clinical and research settings and an essential health outcome measure to assess the effectiveness of medical treatment. However, it has not yet been studied among the healthy siblings of kidney transplant re...

journal_title：Pediatric transplantation

authors： Velasco J,Ferraris JR,Eymann A,Ghezzi LFR,Coccia PA,Ferraris V

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:ADH is a rare and potentially fatal complication following LT. In this study, a systematic review was completed to identify risk factors which may contribute to ADH. METHODS:Transplant databases at three LT programs were reviewed. Four pediatric and zero adult cases were identified. Next, a systematic revie...

journal_title：Pediatric transplantation

authors： Emamaullee JA,Nekrasov V,Gilmour S,Kneteman N,Yanni G,Kohli R,Thomas D,Genyk Y

更新日期：2018-12-01 00:00:00

abstract：:Clinical grading of GI involvement during acute GVHD remains a challenging issue, especially in children. Plasma citrulline, a non-protein amino acid selectively produced and released by enterocytes, is a suitable surrogate endpoint for small intestinal epithelial cell mass, irrespective of the underlying cause of cel...

journal_title：Pediatric transplantation

authors： Merlin E,Minet-Quinard R,Pereira B,Rochette E,Auvrignon A,Oudot C,Sapin V,Deméocq F,Kanold J

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:The understanding of the HRQOL issues for parent donors of children who underwent LDLT is lacking. We evaluated the HRQOL of donor and non-donor parents, described their subjective experiences and identified factors associated with lower HRQOL post-donation. METHODS:This is a cross-sectional study of parent do...

journal_title：Pediatric transplantation

authors： Yuen WY,Tan A,Karthik SV,Quak SH,Kow AW,Aw MM

更新日期：2019-03-01 00:00:00

abstract：:A proportion of patients with CF develop cirrhosis and portal hypertension. LT and combined LLT are rarely performed in patients with CF. To determine the outcome of LT and LLT in patients with CF. Patients with CF who had LT or LLT between 10/1987 and 5/2008 were identified from UNOS database. A total of 182 children...

journal_title：Pediatric transplantation

authors： Arnon R,Annunziato RA,Miloh T,Padilla M,Sogawa H,Batemarco L,Willis A,Suchy F,Kerkar N

更新日期：2011-05-01 00:00:00

abstract：:The availability of new and more effective anti-rejection therapy has succeeded in reducing the incidence of acute cellular rejection in first months post-renal transplant. This in turn has escalated the order of significance of recurrence of primary disease in the renal allograft as a cause for patient morbidity and ...

journal_title：Pediatric transplantation

authors： Seikaly MG

更新日期：2004-04-01 00:00:00

abstract：:We retrospectively analyzed the effects of recombinant human growth hormone (rhGH) in a Belgian population of 36 short children with renal allografts. Seven children were dropped from the growth study: 1 had skeletal dysplasia and in 6 cases rhGH was given for less than 1 yr (1 died, 1 developed genu valgum, 2 were no...

journal_title：Pediatric transplantation

authors： Janssen F,Van Damme-Lombaerts R,Van Dyck M,Hall M,Schurmans T,Herman J,Hooghe L,Van Damme B

更新日期：1997-11-01 00:00:00

abstract：:Early graft loss and poor graft function limit the use of kidneys from infant donors. Six en bloc kidney transplantations were performed from infant donors younger than 10 months into pediatric recipients between November 2012 and September 2015 at our center. We retrospectively analyzed recipient and donor demographi...

journal_title：Pediatric transplantation

authors： Wang HY,Li J,Liu LS,Deng RH,Fu Q,Ko DS,Zhang HX,Deng SX,Wang CX

更新日期：2017-03-01 00:00:00

abstract：:It is the practice of many pediatric renal transplant programs to 'convert' children taking cyclosporin A (CsA) to tacrolimus, although the indications for, outcome, and complications of this practice remain obscure. To better understand these aspects of tacrolimus 'conversion', a fax survey was sent to 119 North Amer...

journal_title：Pediatric transplantation

authors： Flynn JT,Bunchman TE,Sherbotie JR

更新日期：2001-12-01 00:00:00

abstract：:Depression is common in pediatric chronic kidney disease (CKD) patients. Depression is associated with inferior long-term outcomes. There is a paucity of studies that evaluate depression and possible associated factors in children and adolescents requiring renal replacement therapy (RRT). Cross-sectional study using C...

journal_title：Pediatric transplantation

authors： Rodriguez Cuellar CI,García de la Puente S,Hernández Moraria J,Bojórquez Ochoa A,Filler G,Zaltzman Grishevich S

更新日期：2019-12-01 00:00:00

abstract：:Pediatric cardiac transplantation is currently an accepted option for end-stage heart disease and congenital cardiac malformations. This report focuses on the anesthetic perioperative management in 12 yr. From 1988 to 2001 we performed 90 heart transplantations in 88 children, infants and neonates. The pediatric heart...

journal_title：Pediatric transplantation

authors： Schindler E,Müller M,Akintürk H,Valeske K,Bauer J,Zickmann B,Hempelmann G

更新日期：2004-06-01 00:00:00

abstract：:Secondary failure of platelet engraftment occurs in 20% of patients undergoing allogeneic HSCT and is associated with poor outcome. Currently, there are no guidelines for treatment of late thrombocytopenia and platelet transfusion is the mainstay of treatment. Here, we describe the use of Eltrombopag to treat secondar...

journal_title：Pediatric transplantation

authors： Ali S,Gassas A,Kirby-Allen M,Krueger J,Ali M,Schechter T

更新日期：2017-09-01 00:00:00

abstract：:Pediatric solid organ transplant recipients have long-standing malnutrition concerns related to their pretransplant medical status. The targeted nutrition therapy utilized pre-, peri-, and post-transplantation may have the adverse effect of impeding normally developing feeding skills, particularly in very young childr...

journal_title：Pediatric transplantation

authors： Lerret SM,Erato G,Goday PS,Silverman AH

更新日期：2019-05-01 00:00:00

abstract：:We report the occurrence of epididymitis and orchitis 1 week after the onset of Listeriosis in an 11-month-old boy receiving an orthotopic liver transplantation for biliary atresia. Immunologic implications of Listeria monocytogenes-induced testicular inflammation are discussed, and the potential role of immunosuppres...

journal_title：Pediatric transplantation

authors： von Schnakenburg C,Hinrichs B,Fuchs J,Kardorff R

更新日期：2000-05-01 00:00:00

abstract：:Vascular complications remain the most common cause of early renal allograft loss in patients with end-stage renal failure. Underlying thrombophilic disorders increase the risk of early graft thrombosis. A male adolescent with high-risk thrombophilia because of combined heterozygous factor V Leiden (G1691A) and prothr...

journal_title：Pediatric transplantation

authors： John U,Kentouche K,Nowak G,Schubert J,Misselwitz J

更新日期：2006-02-01 00:00:00

abstract：:Deficiency of the CD40L, expressed on the surface of T lymphocytes, is caused by mutations in the glycoprotein CD40L (CD154) gene. Resulting defective humoral and cellular responses cause a clinical presentation that includes recurrent sinopulmonary bacterial infections, opportunistic infections, sclerosing cholangiti...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Karasu GT,Daloğlu H,Öztürkmen SI,Çelmeli F,Törün SH,Özen A,Barış S,Aydıner EK,Yalçın K,Kılıç SÇ,Hazar V,Bingöl A,Yeşilipek A

更新日期：2020-09-01 00:00:00

abstract：:The development of malignancy in a renal transplant graft is an uncommon phenomenon. A renal neoplasm developing in the adult donor kidney of a pediatric transplant recipient has only rarely been reported. We report a case of collecting duct carcinoma arising in association with BK virus nephropathy in an adult living...

journal_title：Pediatric transplantation

authors： Emerson LL,Carney HM,Layfield LJ,Sherbotie JR

更新日期：2008-08-01 00:00:00

abstract：:Myocarditis represents an important cause for acute heart failure. MYKKE, a prospective multicenter registry of pediatric patients with myocarditis, aims to gain knowledge on courses, diagnostics, and therapy of pediatric myocarditis. The role of mechanical circulatory support (MCS) in children with severe heart failu...

journal_title：Pediatric transplantation

authors： Schubert S,Opgen-Rhein B,Boehne M,Weigelt A,Wagner R,Müller G,Rentzsch A,Zu Knyphausen E,Fischer M,Papakostas K,Wiegand G,Ruf B,Hannes T,Reineker K,Kiski D,Khalil M,Steinmetz M,Fischer G,Pickardt T,Klingel K,Messr

更新日期：2019-11-01 00:00:00

abstract：:Dysregulation of genes involved in the cell cycle such as TP53, P21, P16, and PTEN plays a key role in oncogenesis. We have earlier reported increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with more aggressive, rare chronic myeloid malignancies. The aim of this stud...

journal_title：Pediatric transplantation

authors： Mattsson K,Honkaniemi E,Barbany G,Gustafsson B

更新日期：2015-11-01 00:00:00

abstract：:To assess the incidence, risk factors and outcomes of PTDM, a total of 61 non-diabetic children (24 girls, 37 boys, age: 14.5 +/- 2.1 yr) were examined after their first kidney transplantation (37.3 +/- 21.6 months) with an OGTT. At baseline, 16 (26.2%) patients had IGT, 45 (73.8%) had NGT, and no patient had PTDM. No...

journal_title：Pediatric transplantation

authors： Buyan N,Bilge I,Turkmen MA,Bayrakci U,Emre S,Fidan K,Baskin E,Gok F,Bas F,Bideci A

更新日期：2010-03-01 00:00:00

abstract：:Cystic fibrosis (CF) is associated with varying degrees of pleural inflammatory reaction that occurs as a result of chronic pulmonary infections and intervention to pleural space. The amount of pleural reaction is associated with the difficulty involved when performing the pneumonectomy at the time of lung replacement...

journal_title：Pediatric transplantation

authors： Dosanjh A,Jones L,Yuh D,Robbins RC

更新日期：1998-11-01 00:00:00

abstract：:Surgical techniques that have been used during liver transplantation (LT) together with patient's coagulation profile and institutional practices are reported to have an effect on transfusion requirements. The aim of this study is to evaluate the transfusion requirement in both cadaveric (CDLT, n = 22) and living dono...

journal_title：Pediatric transplantation

authors： Ulukaya S,Acar L,Ayanoglu HO

更新日期：2005-06-01 00:00:00

abstract：:Neoplasms in children after organ transplantation are related to the type and intensity of immunosuppression and the donor-recipient serostatus, especially in relation to the Epstein-Barr virus. The patient was a two-yr-old female child with biliary atresia who underwent a liver transplantation from a female cadaver d...

journal_title：Pediatric transplantation

authors： Backes AN,Tannuri AC,de Mello ES,Gibelli NE,de Castro Andrade W,Tannuri U

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Heart transplant waitlist mortality remains high in infants <1 year of age and among those with CHD. Currently, the median accepted donor-to-recipient weight percentage is approximately 130% of the recipient's weight. We hypothesized that patients with CHD may accept a larger organ using novel 3D-derived ima...

journal_title：Pediatric transplantation

authors： Shugh SB,Szugye NA,Zafar F,Riggs KW,Villa C,Lorts A,Morales DLS,Moore RA

更新日期：2020-02-01 00:00:00