Case series and systematic review of acquired diaphragmatic hernia after liver transplantation.


BACKGROUND:ADH is a rare and potentially fatal complication following LT. In this study, a systematic review was completed to identify risk factors which may contribute to ADH. METHODS:Transplant databases at three LT programs were reviewed. Four pediatric and zero adult cases were identified. Next, a systematic review was completed. Fourteen studies describing 41 patients with ADH were identified. Patient demographics, transplant characteristics, and features of ADH diagnosis were examined. RESULTS:The majority (90.2%) of ADH were in children. In pediatric LT, 95.1% received a segmental allograft. ADH occurred in the right P diaphragm 92.7% of the time, and 87.8% were repaired primarily. Patient demographics, post-transplant complications, and immunosuppression regimens were broad and failed to predict ADH. Most patients presented with either respiratory or gastrointestinal symptoms. There were two pediatric deaths related to undiagnosed ADH. The combined worldwide incidence of ADH in pediatric LT is 1.5% (34/2319 patients). CONCLUSION:ADH is a rare complication post-LT that primarily occurs in pediatric recipients. When diagnosed early, ADH can be repaired primarily with good outcomes.


Pediatr Transplant


Emamaullee JA,Nekrasov V,Gilmour S,Kneteman N,Yanni G,Kohli R,Thomas D,Genyk Y




Has Abstract


2018-12-01 00:00:00












  • Ureterocystoplasty (bladder augmentation) with a solitary kidney.

    abstract::Children who develop end-stage renal disease (ESRD) as a result of obstructive uropathies require evaluation and treatment of associated bladder dysfunction to ensure a good outcome following renal transplantation. Bladder dynamics can often be optimized medically, although surgical intervention is occasionally necess...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Kurzrock EA,Butani L,Kakker SP,Perez RV,Lavjay Butani.

    更新日期:2002-06-01 00:00:00

  • Bilateral lung transplant in Gauchers type-1 disease.

    abstract::We report a case of a patient who received a bilateral lung transplant for end-stage lung disease secondary to Gauchers type-1 disease with no evidence of recurrence of the disease in the transplanted lung. ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Rao AR,Parakininkas D,Hintermeyer M,Segura AD,Rice TB

    更新日期:2005-04-01 00:00:00

  • Non-invasive biological quantification of acute gastrointestinal graft-versus-host disease in children by plasma citrulline.

    abstract::Clinical grading of GI involvement during acute GVHD remains a challenging issue, especially in children. Plasma citrulline, a non-protein amino acid selectively produced and released by enterocytes, is a suitable surrogate endpoint for small intestinal epithelial cell mass, irrespective of the underlying cause of cel...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Merlin E,Minet-Quinard R,Pereira B,Rochette E,Auvrignon A,Oudot C,Sapin V,Deméocq F,Kanold J

    更新日期:2013-11-01 00:00:00

  • Latin American Registry of Pediatric Renal Transplantation 2004-2008.

    abstract:UNLABELLED:The Latin American Pediatric Nephrology Association (ALANEPE) reports the first regional kidney transplant registry in Latin America. A mean range of 75%, 30% to 100% renal transplant recipients under 21 yr old were included. Out of 20 countries invited to participate, 14 performed renal transplant, 11 had u...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Latin American Pediatric Nephrology Association.,Latin American Pediatric Renal Transplant Cooperative Study.

    更新日期:2010-09-01 00:00:00

  • Obtaining consensus regarding international transplantation continues to be difficult for pediatric centers in the United States.

    abstract::Organ transplant is life-saving and any given organ may be valuable to a multitude of potential recipients. An allocation system must be used to reconcile the difference between supply and demand, and this system must take into account the impact that accepting international patients may have on the local system. The ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审


    authors: Lorts A,Ryan TD,Matheny Antommaria AH,Lake M,Bucuvalas J

    更新日期:2016-09-01 00:00:00

  • Optimal immunosuppression in teenagers.

    abstract::Adolescence is a difficult time for transplant recipients, who need to cope with the challenges of becoming independent from their parents, as well as taking responsibility for their own behavior and medication. They need to balance their developing sexuality with a body image which may be affected by the side-effects...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审


    authors: Kelly DA

    更新日期:2002-12-01 00:00:00

  • Chronic Mycoplasma pneumoniae infection in a child after renal transplantation.

    abstract::Mycoplasma pneumoniae has rarely been reported in renal transplant recipients. We present the case of a 10-yr-old boy with a six-month history of chronic cough, recurrent pyrexia, and weight loss three yr after RTx. The patient's post-transplant course was complicated by recurrence of NS that resolved with plasmaphere...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Schwerk N,Hartmann C,Baumann U,Pape L,Ehrich JH,Hansen G

    更新日期:2010-05-01 00:00:00

  • Sequential renal and bone marrow transplants in a child with Fanconi anemia.

    abstract::FA is an autosomal recessive disorder characterized by small stature and renal abnormalities. FA can lead to progressive bone marrow failure, myelodysplastic syndrome, or acute leukemia. Using a multidisciplinary team approach, we managed a 3-yr-old boy with FA who simultaneously developed renal and hematopoietic fail...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Vincent CL,Primack WA,Hipps J,Kasow KA

    更新日期:2016-02-01 00:00:00

  • Pediatric heart transplant from an incompletely treated influenza A-positive donor.

    abstract::There is a shortage of pediatric donor hearts for waitlisted children, and yet nearly 50% of organs offered are not transplanted. Donor quality is often cited as a reason for declining organs offered from donors infected with influenza, presumably due to concern about disease transmission at transplant leading to seve...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Smith CJ,McCulloch MD,Shirley DA,L'Ecuyer TJ

    更新日期:2019-12-01 00:00:00

  • Re-evaluation of the indications for liver transplantation in Wilson's disease based on the outcomes of patients referred to a transplant center.

    abstract::The aim of this study was to re-evaluate the indications and timing of LT for WD. From 2000 to 2009, eight patients with WD who had been referred to our institution for LT were enrolled in this study. The mean patient age was 15.9 yr (range, 7-37 yr). Four patients could not receive LT, because there were no available...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Ohya Y,Okajima H,Honda M,Hayashida S,Suda H,Matsumoto S,Lee KJ,Yamamoto H,Takeichi T,Mitsubuchi H,Asonuma K,Endo F,Inomata Y

    更新日期:2013-06-01 00:00:00

  • Single versus en bloc kidney transplant from donors less than or equal to 15 kg to pediatric recipients.

    abstract::With small kidneys, EBKTs could provide sufficient renal mass but could lead to inefficient use of resources, while SKTs could result in insufficient function due to small renal mass. We aimed to compare the outcomes of EBKT and SKT from small donors weighing ≤15 kg to pediatric recipients. We retrospectively reviewed...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Mo H,Ko H,Chung CTY,Kim HK,Han A,Min S,Ha J

    更新日期:2020-05-06 00:00:00

  • High depression rates among pediatric renal replacement therapy patients: A cross-sectional study.

    abstract::Depression is common in pediatric chronic kidney disease (CKD) patients. Depression is associated with inferior long-term outcomes. There is a paucity of studies that evaluate depression and possible associated factors in children and adolescents requiring renal replacement therapy (RRT). Cross-sectional study using C...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Rodriguez Cuellar CI,García de la Puente S,Hernández Moraria J,Bojórquez Ochoa A,Filler G,Zaltzman Grishevich S

    更新日期:2019-12-01 00:00:00

  • Surveillance transbronchial biopsies in infant lung and heart-lung transplant recipients.

    abstract::There are limited published data on surveillance TBB for the identification of allograft rejection in infants after lung or heart-lung transplantation. We performed a retrospective review of children under one yr of age who underwent lung or heart-lung transplant at our institution. Since 2005, four infants were trans...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Hayes D Jr,Baker PB,Kopp BT,Kirkby S,Galantowicz M,McConnell PI,Astor TL

    更新日期:2013-11-01 00:00:00

  • Outcome of hematopoietic stem cell transplant in children with congenital heart disease.

    abstract::CHD is the most commonly occurring birth defect in the United States. Improvements in supportive care for CHD result in increasing numbers of survivors who may develop benign or malignant conditions for which HSCT is indicated. However, the ability of individuals with CHD to tolerate HSCT is unknown. Retrospective med...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Guinan EC,Hewett EK,Domaney NM,Margossian R

    更新日期:2011-02-01 00:00:00

  • Right-sided diaphragmatic hernia after orthotopic liver transplantation: report of two cases.

    abstract::Diaphragmatic hernia after OLT is a rare surgical complication. We here report successful diagnosis and treatment of two cases with right-sided diaphragmatic hernia developed after OLT both utilizing left-sided allografts. Combination of factors related to the surgical techniques and patient characteristics might expl...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Kazimi M,Ibis C,Alper I,Ulas M,Baran M,Arikan C,Aydogdu S,Ulukaya S,Zeytunlu M,Kilic M

    更新日期:2010-08-01 00:00:00

  • Significance of Epstein-Barr virus status and post-transplant lymphoproliferative disease in pediatric thoracic transplantation.

    abstract::Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) is a serious complication of organ and bone marrow transplantation. The importance of EBV matching between recipient and donor remains unclear. Between October 1987 and December 1997, 64 pediatric cardio-pulmonary transplants were p...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Harwood JS,Gould FK,McMaster A,Hamilton JR,Corris PA,Hasan A,Gennery AR,Dark JH

    更新日期:1999-05-01 00:00:00

  • Successful percutaneous transhepatic recanalization of a completely obstructed hepatico-jejunal anastomosis in a child with liver transplantation: Unusual employment of the transseptal puncture system.

    abstract::Stenosis of the HJ is a common complication of pediatric split LT with high morbidity and possible evolution to secondary biliary cirrhosis and re-transplantation if not treated. Because the endoscopy is generally infeasible in the Roux-en-Y, percutaneous interventional radiology management is usually the safest and m...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Paolantonio G,Pietrobattista A,Parapatt GK,Liccardo D,Natali GL,Candusso M,Spada M,Rollo M,Tomà P

    更新日期:2018-12-01 00:00:00

  • Unrelated donor hematopoietic stem cell transplantation for pediatric de novo acute myeloid leukemia with intermediate- or high-risk cytogenetics.

    abstract::The role of unrelated donor HSCT for children with de novo AML in CR1 is controversial. We performed this study to investigate the feasibility of unrelated donor HSCT who initially had intermediate- or high-risk cytogenetics. We retrospectively reviewed medical records of patients with AML who received unrelated HSCT ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Park EG,Yi ES,Choi YB,Sung KW,Koo HH,Yoo KH

    更新日期:2019-06-01 00:00:00

  • Chronic kidney disease in children following lung and heart-lung transplantation.

    abstract::CKD is a major co-morbidity in pediatric lung transplant recipients. We report the prevalence of renal impairment post-lung transplant at a single center, using a modified, age-adjusted eGFR for the best approximation of true GFR, and investigated associations and possible predictors of decline in renal function post-...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Benden C,Kansra S,Ridout DA,Shaw NL,Aurora P,Elliott MJ,Marks SD

    更新日期:2009-02-01 00:00:00

  • Living donor liver transplantation with alternative porto-left gastric vein anastomosis in patients with post-Kasai extrahepatic portal vein obstruction.

    abstract::EPVO is a common cause of prehepatic portal hypertension in pediatric patients and sometimes results in cavernous transformation of the PV. We herein present the cases of two patients who underwent LDLT for EPVO with post-Kasai biliary atresia. PV reconstruction was performed with a porto-left gastric vein anastomosis...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Kitajima T,Sakamoto S,Uchida H,Hamano I,Kobayashi M,Kanazawa H,Fukuda A,Kasahara M

    更新日期:2013-05-01 00:00:00

  • Impact of donor cardiopulmonary resuscitation on pediatric heart transplant outcome.

    abstract::Mortality is the highest of any solid organ in pediatric patients awaiting heart transplantation. Strategies to increase the donor pool are needed if survival to transplant is to improve. There can be reluctance to accept pediatric hearts for transplantation if the donor has received cardiopulmonary resuscitation (CPR...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: L'Ecuyer T,Sloan K,Tang L

    更新日期:2011-11-01 00:00:00

  • Infection profile in children and adolescents with bone marrow failures treated with allogeneic hematopoietic stem cell transplantation.

    abstract:BACKGROUND:The objective of the study was to analyze the profile of infections in children with BMF following alloHCT. METHODS:Data of 169 consecutive children with inherited and acquired BMF treated with alloHCT between 2012 and 2017 in Polish pediatric transplant departments were analyzed in registry-based retrospec...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Zaucha-Prażmo A,Zawitkowska J,Lejman M,Kowalczyk JR,Czyżewski K,Dziedzic M,Pieczonka A,Zając-Spychała O,Goździk J,Frączkiewicz J,Salamonowicz M,Gorczyńska E,Kałwak K,Wachowiak J,Styczyński J

    更新日期:2019-12-01 00:00:00

  • Matched related donor hematopoietic stem cell transplantation results in a long-term follow-up of a pediatric acquired severe aplastic anemia subset: A stem cell source perspective.

    abstract::HSCT has substantially improved pediatric acquired SAA patients' outcomes. Retrospectively, we attempted to assess the outcome of MRD HSCT in 65 pediatric patients referred to a single center from 1992 to 2012. We were particularly interested to find out whether source of SC (PB, n = 40 and BM, n = 25) significantly i...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Hamidieh AA,Mozafari M,Noshad S,Alimoghaddam K,Behfar M,Ghavamzadeh A

    更新日期:2015-06-01 00:00:00

  • Cognitive abilities, behaviour and quality of life in children after liver transplantation.

    abstract:AIMS:We investigated interrelations between cognitive abilities, behavioural problems, quality of life and disease-related variables of children after LTX. METHODS:Our sample consisted of 25 children. They were 8.5/2.8 (M/SD) years old and had received the transplant 5.5/3.1 years previously. For assessment we used we...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Kaller T,Boeck A,Sander K,Richterich A,Burdelski M,Ganschow R,Schulz KH

    更新日期:2010-06-01 00:00:00

  • The impact of length and weight on survival after heart transplantation in children less than 24 months of age.

    abstract::Adults, older children, and adolescent patients with a BMI categorized as overweight or obese have decreased survival after HTx. Anthropometric correlates of survival after HTx in infants have not been well defined. In a retrospective analysis of the UNOS registry, patients age 0-24 months were classified according to...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: McKee C,Tumin D,Hayes D Jr,Tobias JD

    更新日期:2016-12-01 00:00:00

  • Pediatric cardiac waitlist mortality-Still too high.

    abstract::Cardiac transplantation for children with end-stage cardiac disease with no other medical or surgical options is now standard. The number of children in need of cardiac transplant continues to exceed the number of donors considered "acceptable." Therefore, there is an urgent need to understand which recipients are in ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审


    authors: Denfield SW,Azeka E,Das B,Garcia-Guereta L,Irving C,Kemna M,Reinhardt Z,Thul J,Dipchand AI,Kirk R,Davies RR,Miera O

    更新日期:2020-05-01 00:00:00

  • Evaluation of a three-session biliary dilation protocol following transplant-related biliary stricture in pediatric patients.

    abstract::To evaluate whether a serial biliary dilation protocol improves outcomes and decreases total biliary drainage time for biliary strictures following pediatric liver transplantation. From 2006 to 2016, 213 orthotopic deceased and living related liver transplants were performed in 199 patients with a median patient age o...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Reis SP,Bruestle K,Brejt S,Tulin-Silver S,Frenkel J,Mobley DG,England RW,Sobolevsky S,Griesemer AD,Sperling D,Schlossberg P,Susman J,Weintraub JL

    更新日期:2019-11-01 00:00:00

  • Acute lymphoblastic leukaemia: whom and when should we transplant?

    abstract::To date, the evidence upon which a decision is made to transplant a child with acute lymphoblastic leukaemia either in first or subsequent remission has rarely been based on randomized trial data. Modern era management of infection and graft-versus-host disease lessens risks but procedure-related deaths still remain h...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审


    authors: Eden OB

    更新日期:1999-01-01 00:00:00

  • Successful liver retransplantation for recurrent hepatopulmonary syndrome.

    abstract::HPS is defined as arterial hypoxemia because of pulmonary vasodilation as a result of cirrhotic or non-cirrhotic portal hypertension. This report describes a teenager with HPS because of primary sclerosing cholangitis/autoimmune hepatitis overlap syndrome requiring OLT. HPS resolved completely within three months of O...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Rajwal SR,Davison SM,Prasad R,Brownlee K,McClean P

    更新日期:2007-12-01 00:00:00

  • Recurrent and de novo disease after renal transplantation: a report from the Renal Allograft Disease Registry.

    abstract::Recurrent and de novo disease is an increasing problem and is known to negatively impact transplant graft survival. Immunosuppressive medications have not had an impact on the prevalence of recurrent and de novo disease. Renal Allograft Disease Registry (RADR) was established to study the prevalence, impact and risk f...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章


    authors: Hariharan S,Savin VJ

    更新日期:2004-08-01 00:00:00