Hepatitis C viral recurrence in a pediatric patient following liver transplantation.

Abstract:

:Hepatitis C virus (HCV) infections are known to have a more benign course in children than in adults. Although the natural history of HCV recurrence after liver transplantation has been well studied in adult patients, much less is known about HCV recurrence after liver transplantation in pediatric patients. Herein, we report a case of a pediatric patient with HCV presumably acquired through vertical transmission. She underwent liver transplantation at 14 yr of age. The first three yr after liver transplantation were uneventful. However, in the past 12 months she has been hospitalized twice after developing ascites, hematemesis and esophagogastroduodenoscopy (EGD)-documented esophageal varices. Post-transplant biopsy has demonstrated chronic inflammation complicated with active hepatitis C and stage 2-3 scarring. This case report demonstrates the need for further epidemiologic studies to study the natural history of the rate of HCV recurrence after liver transplantation in the pediatric population.

journal_name

Pediatr Transplant

authors

Udell IW,Barshes NR,Finegold MJ,Lee TC,Scott JD,Carter B,Karpen S,Goss JA

doi

10.1111/j.1399-3046.2006.00519.x

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

617-22

issue

5

eissn

1397-3142

issn

1399-3046

pii

PTR519

journal_volume

10

pub_type

杂志文章
  • Recurrence of primary disease in children after renal transplantation: an evidence-based update.

    abstract::The availability of new and more effective anti-rejection therapy has succeeded in reducing the incidence of acute cellular rejection in first months post-renal transplant. This in turn has escalated the order of significance of recurrence of primary disease in the renal allograft as a cause for patient morbidity and ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1046/j.1399-3046.2003.00151.x

    authors: Seikaly MG

    更新日期:2004-04-01 00:00:00

  • Preliminary quantitative investigation of predictors of treatment non-adherence in pediatric transplantation: a brief report.

    abstract::The examination of predictors of non-adherence in transplantation populations offers the potential to identify high-risk individuals and concomitantly generate effective adherence-promoting interventions. The present paper aggregated quantitative estimates of various correlates of treatment adherence in studies of ped...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,meta分析

    doi:10.1111/j.1399-3046.2007.00864.x

    authors: Kahana SY,Frazier TW,Drotar D

    更新日期:2008-09-01 00:00:00

  • Fludrocortisone-a treatment for tubulopathy post-paediatric renal transplantation: A national paediatric nephrology unit experience.

    abstract::Calcineurin inhibitors post-renal transplantation are recognized to cause tubulopathies in the form of hyponatremia, hyperkalemia, and acidosis. Sodium supplementation may be required, increasing medication burden and potentially resulting in poor compliance. Fludrocortisone has been beneficial in addressing tubulopat...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13134

    authors: Ali SR,Shaheen I,Young D,Ramage I,Maxwell H,Hughes DA,Athavale D,Shaikh MG

    更新日期:2018-03-01 00:00:00

  • Association of mast cells and liver allograft rejection.

    abstract::MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2007.00819.x

    authors: Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

    更新日期:2008-05-01 00:00:00

  • Educational needs in families of pediatric liver and kidney transplant recipients: A quality improvement project.

    abstract::Parents of pediatric liver and kidney transplant recipients were surveyed regarding their current education plans (eg, Individualized Education Program, 504), satisfaction with these plans, and interest in educational support from the psychosocial transplant team. Survey results indicate high rates of IEP and 504 plan...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13412

    authors: daCruz K,Cousino MK,Smith T,Bilhartz J,Eder SJ,Fredericks EM

    更新日期:2019-06-01 00:00:00

  • Neurologic outcome of urea cycle disorder liver transplant recipients may be predicted by pretransplant neurological imaging.

    abstract:UNLABELLED:Liver transplantation treats the hepatic affectation of UCDs; however, irreversible neurologic damage pretransplant is difficult to assess providing transplant teams with ethical dilemmas for liver transplantation. The purpose of our study was to determine whether pretransplant neuroimaging can predict devel...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12520

    authors: Bolton SM,Campbell KM,Kukreja M,Kohli R

    更新日期:2015-08-01 00:00:00

  • Imaging in pediatric renal transplantation.

    abstract::Renal transplantation is the therapy of choice in children with ESKD. Radiological investigations are required in both pre- and post-transplant assessment, although there is paucity of both consensus-based statements and evidence-based imaging guidelines in pediatric renal transplantation. The phases of pediatric ESKD...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/petr.12885

    authors: Damasio MB,Ording Muller LS,Piaggio G,Marks SD,Riccabona M

    更新日期:2017-05-01 00:00:00

  • Out-of-reach obscure bleeding: single-balloon enteroscopy to diagnose and treat varices in hepaticojejunostomy after pediatric liver transplant.

    abstract::Obscure gastrointestinal (GI) bleeding is defined as bleeding from the GI tract that persists or recurs, with no obvious etiology, after esophagogastroduodenoscopy (EGD), colonoscopy, and radiologic evaluation of the small bowel. We present the case of a 17-yr-old girl who for two years had been suffering from recurre...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2010.01425.x

    authors: Curcio G,Sciveres M,Mocciaro F,Riva S,Spada M,Tarantino I,Barresi L,Traina M

    更新日期:2012-05-01 00:00:00

  • Evaluation of arterial structure and function in pediatric patients with end-stage renal disease on dialysis and after renal transplantation.

    abstract::CVD is a major cause of morbidity and mortality in pediatric patients with CKD. It is unclear whether vascular abnormalities in these patients are reversible, and if transplantation portends salutary effects on arterial function. We compared FMD, PWV, AI75, and CIMT in 15 dialysis (D), 14 transplant patients (T), and ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2012.01721.x

    authors: Tawadrous H,Kamran H,Salciccioli L,Schoeneman MJ,Lazar J

    更新日期:2012-08-01 00:00:00

  • Characteristics of long-term live-donor pediatric renal transplant survivors: a single-center experience.

    abstract:OBJECTIVES:To study the characteristics and the predictors of survival observed in our pediatric live-donor renal transplant recipients with an allograft that functioned for more than 10 yr. METHODS:One hundred fifteen children underwent renal transplantation between 1976 and 1995. Of these, 30 had functioning allogra...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2005.00455.x

    authors: El-Husseini AA,Foda MA,Osman YM,Sobh MA

    更新日期:2006-05-01 00:00:00

  • Case series and systematic review of acquired diaphragmatic hernia after liver transplantation.

    abstract:BACKGROUND:ADH is a rare and potentially fatal complication following LT. In this study, a systematic review was completed to identify risk factors which may contribute to ADH. METHODS:Transplant databases at three LT programs were reviewed. Four pediatric and zero adult cases were identified. Next, a systematic revie...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13296

    authors: Emamaullee JA,Nekrasov V,Gilmour S,Kneteman N,Yanni G,Kohli R,Thomas D,Genyk Y

    更新日期:2018-12-01 00:00:00

  • A trial of plerixafor adjunctive therapy in allogeneic hematopoietic cell transplantation with minimal conditioning for severe combined immunodeficiency.

    abstract::For infants with SCID, the ideal conditioning regimen before allogeneic HCT would omit cytotoxic chemotherapy to minimize short- and long-term complications. We performed a prospective pilot trial with G-CSF plus plerixafor given to the host to mobilize HSC from their niches. We enrolled six patients who received CD34...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12309

    authors: Dvorak CC,Horn BN,Puck JM,Czechowicz A,Shizuru JA,Ko RM,Cowan MJ

    更新日期:2014-09-01 00:00:00

  • Does renal transplant in children with LUTD improve their bladder function?

    abstract::Much is still unknown about LUT function after receiving renal graft. Graft function was the main focus of different studies discussing the same issue. However, these studies ignored the effects of the graft on lower tract function and more demand for bladder cycling and growth of the child. Therefore, we aimed at eva...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13735

    authors: Aboulela W,Fawzy AM,Abdelmawla MA,Salah DM,Eldin MS,Mohamed Anwar AZ,El Ghoneimy M,Shouman AM,Shoukry AI,Bazaraa H,Tawfiek ER,Fadel F,Badawy H,Morsi HA,Ghoneima W

    更新日期:2020-09-01 00:00:00

  • Castleman disease in a pediatric liver transplant recipient: a case report and literature review.

    abstract::Castleman disease is a rare hematologic disorder, closely linked to the HHV-8, and most commonly observed in immunocompromised individuals. Thirteen months following a liver transplant for CPS-1 defect, a 15-month-old boy presented with fevers, anemia, and growth retardation. Abdominal CT scan showed splenomegaly and ...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-3046.2011.01570.x

    authors: Bonatti HJ,Axt J,Hunter EB,Lott SL,Frangoul H,Gillis L,Correa H,Kelly B

    更新日期:2012-09-01 00:00:00

  • The efficacy of serum brain natriuretic peptide for the early detection of portopulmonary hypertension in biliary atresia patients before liver transplantation.

    abstract::Severe portopulmonary hypertension (POPH) is a contraindication for liver transplantation (LT) because of the high risk of postoperative heart failure. The early detection of POPH is important for patients with biliary atresia (BA). Brain natriuretic peptide (BNP) is known to be correlated with liver fibrosis in patie...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13203

    authors: Yoshimaru K,Matsuura T,Takahashi Y,Yanagi Y,Nagata H,Ohga S,Taguchi T

    更新日期:2018-08-01 00:00:00

  • The impact of RSV, adenovirus, influenza, and parainfluenza infection in pediatric patients receiving stem cell transplant, solid organ transplant, or cancer chemotherapy.

    abstract::RVIs are a significant cause of morbidity and mortality in immunocompromised children. We analyzed the characteristics and outcomes of infection by four respiratory viruses (RSV, adenovirus, influenza, and parainfluenza) treated at a pediatric tertiary care hospital in a retrospective cohort of patients who had receiv...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12022

    authors: Lo MS,Lee GM,Gunawardane N,Burchett SK,Lachenauer CS,Lehmann LE

    更新日期:2013-03-01 00:00:00

  • Preemptive plasmapheresis and recurrence of focal segmental glomerulosclerosis in pediatric renal transplantation.

    abstract::  FSGS has a high recurrence rate after renal transplantation. To examine the effects of the use of preemptive and post-transplant PP on recurrence and graft outcome, we conducted a retrospective study on 34 pediatric patients (mean age 13±5 yr) with biopsy-proven pretransplant FSGS and who underwent a renal transplan...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2011.01478.x

    authors: Gonzalez E,Ettenger R,Rianthavorn P,Tsai E,Malekzadeh M

    更新日期:2011-08-01 00:00:00

  • Behavioral economics-A framework for donor organ decision-making in pediatric heart transplantation.

    abstract::The high discard rate of pediatric donor hearts presents a major challenge for children awaiting heart transplantation. Recent literature identifies several factors that contribute to the disparities in pediatric donor heart usage, including regulatory oversight, the absence of guidelines on pediatric donor heart acce...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/petr.13655

    authors: Butler A,Chapman G,Johnson JN,Amodeo A,Böhmer J,Camino M,Davies RR,Dipchand AI,Godown J,Miera O,Pérez-Blanco A,Rosenthal DN,Zangwill S,Kirk R

    更新日期:2020-05-01 00:00:00

  • Use of radiolabeled antibodies in the treatment of childhood acute leukemia.

    abstract::Despite advances in therapy for acute leukemia, relapse continues to be the major cause of treatment failure. Hematopoietic stem cell transplant can rescue some patients after relapse, but the ability to escalate the intensity of preparative regimens is limited by toxicity to normal organs. Radiolabeled monoclonal ant...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1034/j.1399-3046.7.s3.14.x

    authors: Nemecek ER,Matthews DC

    更新日期:2003-01-01 00:00:00

  • Effect of CYP3A5*1 expression on tacrolimus required dose for transplant pediatrics: A systematic review and meta-analysis.

    abstract::This systematic review was designed to find out optimal tacrolimus dose in pediatrics according to their CYP3A5*1 genotype by performing meta-analysis. PubMed, Scopus, ISI web of Science, ProQuest, Cochrane library, and clinicaltrail.gov were systematically searched to find studies in which tacrolimus dose and/or bloo...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/petr.13248

    authors: Hendijani F,Azarpira N,Kaviani M

    更新日期:2018-06-19 00:00:00

  • Quantitation of allograft fibrosis and chronic allograft nephropathy.

    abstract::Despite improvements in the prevention and treatment of acute renal allograft rejection, the long-term survival of renal transplants has not increased. Immunologic and non-immunologic factors contribute to the gradual deterioration of graft function and to the histologic lesion characterized by vascular and interstiti...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1034/j.1399-3046.1999.00044.x

    authors: Grimm PC,Nickerson P,Gough J,McKenna R,Jeffery J,Birk P,Rush DN

    更新日期:1999-11-01 00:00:00

  • High prevalence of latent tuberculosis in hematopoietic stem cell transplant recipients: A First Report.

    abstract::TB is an increasing health problem, and patients undergoing HSCT are more prone to develop tuberculosis. The aim of our study was to evaluate prevalence of latent tuberculosis in HSCT recipients. In this study, 84 patients (2 months to 18 years) who were candidates for HSCT at the referral hospital of Tehran Children'...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13770

    authors: Mahmoudi S,Pourakbari B,Sadeghi RH,Hamidieh AA,Safari Sharari A,Salajegheh P,Aziz-Ahari A,Mamishi S

    更新日期:2020-09-01 00:00:00

  • Ethical issues in pediatric face transplantation.

    abstract::Facial transplantation has become a reality in adult medicine. Children are subject to congenital craniofacial differences, disease-related, traumatic, or thermochemical craniofacial changes and might be suitable for face transplantation. This manuscript addresses unique ethical issues in considering potential pediatr...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13032

    authors: Benghiac AG,Garrett JR,Carter BS

    更新日期:2017-11-01 00:00:00

  • Bilateral laparoscopic nephrectomy with simultaneous peritoneal dialysis catheter implantation.

    abstract::Bilateral nephrectomy prior to transplantation is indicated in some patients with end-stage renal disease. The indications for bilateral nephrectomy include persistent heavy proteinuria, refractory hypertension, and urinary tract infections. We report an eight-month-old baby with male pseudohermaphroditism and renal f...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2006.00624.x

    authors: Martínez Urrutia MJ,Olivares Arnal P,López Pereira P,Lobato Romera R,Alonso Melgar A,Jaureguizar Monereo E

    更新日期:2007-03-01 00:00:00

  • Acute lymphoblastic leukaemia: whom and when should we transplant?

    abstract::To date, the evidence upon which a decision is made to transplant a child with acute lymphoblastic leukaemia either in first or subsequent remission has rarely been based on randomized trial data. Modern era management of infection and graft-versus-host disease lessens risks but procedure-related deaths still remain h...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1034/j.1399-3046.1999.00055.x

    authors: Eden OB

    更新日期:1999-01-01 00:00:00

  • Combined liver-kidney transplantation for primary hyperoxaluria type I in children: Single Center Experience.

    abstract::Primary hyperoxalurias are rare inborn errors of metabolism with deficiency of hepatic enzymes that lead to excessive urinary oxalate excretion and overproduction of oxalate which is deposited in various organs. Hyperoxaluria results in serious morbid-ity, end stage kidney disease (ESKD), and mortality if left untreat...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13313

    authors: Kotb MA,Hamza AF,Abd El Kader H,El Monayeri M,Mosallam DS,Ali N,Basanti CWS,Bazaraa H,Abdelrahman H,Nabhan MM,Abd El Baky H,El Sorogy STM,Kamel IEM,Ismail H,Ramadan Y,Abd El Rahman SM,Soliman NA

    更新日期:2019-02-01 00:00:00

  • Favorable four-yr outcome after renal transplantation in a patient with complement factor H antibody and CFHR1/CFHR3 gene mutation-associated HUS.

    abstract:UNLABELLED:aHUS is a clinical challenge for successful renal transplantation. CASE REPORT:A 14-yr-old girl lost her kidneys at the age of 7, due to CFH antibodies and CFH-related protein (CFHR1/CFHR3) homozygous deletion-associated aHUS. CFH, CFI, and MCP gene mutations were excluded. The patient was a candidate for r...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12537

    authors: Grenda R,Jarmużek W,Rubik J,Prokurat S,Miklaszewska M,Drozdz D,Zachwieja K,Ardissino G,Hofer J

    更新日期:2015-09-01 00:00:00

  • Impact of donor preprocurement cardiac arrest on clinical outcomes in pediatric deceased donor liver transplantation.

    abstract::PPCA has historically been considered detrimental to donor quality in LT, but transplantation of grafts from this group of donors is now routine. Our study aims to evaluate the outcomes associated with use of donors with a history of PPCA in the pediatric population. This study is a single-center retrospective analysi...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13701

    authors: Schroering JR,Hathaway TJ,Kubal CA,Ekser B,Mihaylov P,Mangus RS

    更新日期:2020-08-01 00:00:00

  • Coronary artery involvement in chronic graft-versus-host disease presenting as sudden cardiac arrest.

    abstract::Graft-versus-host disease (GVHD) is related to considerable morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Cardiac complications associated with GVHD are uncommon, and coronary artery involvement is even more unusual. We report on a male pediatric patient with chronic GVHD who...

    journal_title:Pediatric transplantation

    pub_type:

    doi:10.1111/petr.13474

    authors: Kim DH,You JJ,Im HJ,Ko JK

    更新日期:2019-08-01 00:00:00

  • Successful renal transplantation in a patient with heterozygous prothrombin gene, factor V Leiden mutation and heparin-induced thrombocytopenia using r-hirudin as anticoagulant.

    abstract::Vascular complications remain the most common cause of early renal allograft loss in patients with end-stage renal failure. Underlying thrombophilic disorders increase the risk of early graft thrombosis. A male adolescent with high-risk thrombophilia because of combined heterozygous factor V Leiden (G1691A) and prothr...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2005.00398.x

    authors: John U,Kentouche K,Nowak G,Schubert J,Misselwitz J

    更新日期:2006-02-01 00:00:00