Preliminary quantitative investigation of predictors of treatment non-adherence in pediatric transplantation: a brief report.

abstract：:Methylmalonic acidemia with complete mutase deficiency (mut(0) type) is an inborn error of metabolism with high mortality and morbidity. LT has been suggested to be a solution to this disease, but elevation of urinary and blood MMA was still observed after LT. In this study, we measured dry blood spot MMA and its prec...

journal_title：Pediatric transplantation

authors： Chen PW,Hwu WL,Ho MC,Lee NC,Chien YH,Ni YH,Lee PH

更新日期：2010-05-01 00:00:00

abstract：:Dysregulation of genes involved in the cell cycle such as TP53, P21, P16, and PTEN plays a key role in oncogenesis. We have earlier reported increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with more aggressive, rare chronic myeloid malignancies. The aim of this stud...

journal_title：Pediatric transplantation

authors： Mattsson K,Honkaniemi E,Barbany G,Gustafsson B

更新日期：2015-11-01 00:00:00

abstract：:De novo PTAID may develop in pediatric solid organ transplant recipients, have a diverse spectrum, and are occasionally treatment resistant. Previous reports showed resolution of immune cytopenias in solid organ transplant recipients following replacement of the calcineurin inhibitor tacrolimus with the mTOR inhibitor...

journal_title：Pediatric transplantation

authors： Kehar M,Grunebaum E,Jimenez-Rivera C,Mozer-Glassberg Y,Jamal A,Ng VL,Avitzur Y

更新日期：2020-09-01 00:00:00

abstract：:EBV is associated with various malignancies in patients with acquired or induced immune impairment. EBV-SMT is very uncommon in immunocompromised patients, and a kidney localization has been described only anecdotally. We report the case of a 17-yr-old kidney transplant recipient diagnosed as having an EBV-SMT inside ...

journal_title：Pediatric transplantation

authors： Belingheri M,Comoli P,Locatelli F,Baldanti F,Martina V,Giani M,Ferraresso M,Cro L,Edefonti A,Ghio L

更新日期：2010-12-01 00:00:00

abstract：:LDLT is a well-established treatment for most terminal liver diseases in children. Survival rates have improved, yet few studies have considered HRQoL or sleep problems in LDLT recipients. In this cross-sectional study, we enrolled 51 children who had undergone LDLT in Renji Hospital. PedsQL(™) 4.0 Generic Core Scales...

journal_title：Pediatric transplantation

authors： He K,Shen C,Chen X,Han L,Xi Z,Zhou T,Zhang J,Xia Q

更新日期：2015-08-01 00:00:00

abstract：:This review focuses on active clinical research in pediatric liver transplantation with special emphasis on areas that could benefit from studies utilizing the SPLIT infrastructure and data repository. Ideas were solicited by members of the SPLIT Research Committee and sections were drafted by members of the committee...

journal_title：Pediatric transplantation

authors： Alonso EM,Ng VL,Anand R,Anderson CD,Ekong UD,Fredericks EM,Furuya KN,Gupta NA,Lerret SM,Sundaram S,Tiao G,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Liver transplantation (LT) has been accepted as a standard treatment of pediatric liver diseases that can progress to end-stage liver disease or lead to acute liver failure. However, there is a lack of studies clarifying quality of life (QoL) and the characteristics and the prevalence of common psychiatric d...

journal_title：Pediatric transplantation

authors： Ünay M,Önder A,Gizli Çoban Ö,Atalay A,Sürer Adanir A,Artan R,Özatalay E

更新日期：2020-02-01 00:00:00

abstract：:To evaluate whether a serial biliary dilation protocol improves outcomes and decreases total biliary drainage time for biliary strictures following pediatric liver transplantation. From 2006 to 2016, 213 orthotopic deceased and living related liver transplants were performed in 199 patients with a median patient age o...

journal_title：Pediatric transplantation

authors： Reis SP,Bruestle K,Brejt S,Tulin-Silver S,Frenkel J,Mobley DG,England RW,Sobolevsky S,Griesemer AD,Sperling D,Schlossberg P,Susman J,Weintraub JL

更新日期：2019-11-01 00:00:00

abstract：:CHS is a rare immunodeficiency syndrome with defects in the functions of cytotoxic cells and neutrophils. Approximately 85% of patients with CHS undergo an AP within the first decade, which is similar to FHLH. Chemotherapy could induce transient remission, but only allogeneic HCT could correct the underlying genetic d...

journal_title：Pediatric transplantation

authors： Zhang Y,Gao Z,Yu X

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:To study the characteristics and the predictors of survival observed in our pediatric live-donor renal transplant recipients with an allograft that functioned for more than 10 yr. METHODS:One hundred fifteen children underwent renal transplantation between 1976 and 1995. Of these, 30 had functioning allogra...

journal_title：Pediatric transplantation

authors： El-Husseini AA,Foda MA,Osman YM,Sobh MA

更新日期：2006-05-01 00:00:00

abstract：:Omenn's syndrome is a rare inherited variant of SCID. It is inevitably fatal, unless treated by bone marrow or stem cell transplantation. However, treatment-related complications and graft rejection are major obstacles to the success of transplantation. In this report, we describe an eight-month-old baby with Omenn's ...

journal_title：Pediatric transplantation

authors： Wahadneh A,Bin-Dahman H,Habahbeh Z,Abu-Shukear M,Ajarmeh M,Zyood R,Khaled A

更新日期：2012-03-01 00:00:00

abstract：:This study examined patient-reported sleep quality in a single-center cross-sectional sample of adolescents with solid organ transplants and evaluated associations between sleep quality, psychosocial functioning (ie, depression/anxiety symptoms), and HRQOL. Health disparities associated with minority race/ethnicity an...

journal_title：Pediatric transplantation

authors： Gutierrez-Colina AM,Quast LF,Eaton CK,LaMotte J,Stolz MG,Mee L,George R,Lee J,Reed B,Rich KL,Blount RL

更新日期：2019-12-01 00:00:00

abstract：:Treatment of severe aplastic anemia (SAA) patients who lack human leukocyte antigen (HLA)-matched donors and failed immunosuppressive therapy (IST) is challenging. Recently, umbilical cord blood transplantation (CBT) after non-myeloablative therapy has been reported in adult but not in childhood SAA. However, most cas...

journal_title：Pediatric transplantation

authors： Ohga S,Ichino K,Goto K,Hattori S,Nomura A,Takada H,Nakamura K,Hara T

更新日期：2006-06-01 00:00:00

abstract：:A proportion of patients with CF develop cirrhosis and portal hypertension. LT and combined LLT are rarely performed in patients with CF. To determine the outcome of LT and LLT in patients with CF. Patients with CF who had LT or LLT between 10/1987 and 5/2008 were identified from UNOS database. A total of 182 children...

journal_title：Pediatric transplantation

authors： Arnon R,Annunziato RA,Miloh T,Padilla M,Sogawa H,Batemarco L,Willis A,Suchy F,Kerkar N

更新日期：2011-05-01 00:00:00

abstract：:Cryptosporidium is an intracellular protozoa that can cause gastroenteritis in humans. In immunocompromised hosts, infection can be severe, leading to life-threatening persistent diarrhea. There is limited experience in treating this infection in solid organ transplants. Although newer drugs active against Cryptospori...

journal_title：Pediatric transplantation

authors： Hong DK,Wong CJ,Gutierrez K

更新日期：2007-02-01 00:00:00

abstract：:We reviewed 112 pediatric renal transplant recipients to document the rate of medication non-adherence (NA) and to examine the relationships between NA, comorbid psychiatric illness, and the outcome variables of acute and chronic rejection and graft loss. A total of 32.5% of subjects had clinically significant NA with...

journal_title：Pediatric transplantation

authors： Shaw RJ,Palmer L,Blasey C,Sarwal M

更新日期：2003-12-01 00:00:00

abstract：:This retrospective case series reviews our center's experience with sirolimus and a CNI as alternative therapy for the treatment of PTAH. It also characterizes regulatory T cells (Tregs) in PTAH. LT recipients with PTAH who had received or were receiving treatment with sirolimus were retrospectively identified (n = 12...

journal_title：Pediatric transplantation

authors： Ekong UD,Mathew J,Melin-Aldana H,Wang D,Alonso EM

更新日期：2012-03-01 00:00:00

abstract：:Success after solid organ transplantation is dependent on the proper balance of immunosuppression to prevent rejection of the allograft while limiting the risk of developing infections and malignancy. We present a 9-year-old girl, remote from transplant, who presented with airway plaque after a change in immunosuppres...

journal_title：Pediatric transplantation

authors： Ryan TD,Absalon MJ,de Alarcon A,Gupta A,Peters AL,Lorts A,Danziger-Isakov LA,Chin C

更新日期：2017-11-01 00:00:00

abstract：:This report describes a successful renal Tx in a patient with chronic renal failure, caused by dysplastic kidneys, who received a cadaveric kidney with post-infectious glomerulonephritis. Sequential renal biopsies were performed at 12 h before Tx, and at 1 h and on days 8 and 58 post-Tx. Post-operative hematuria disap...

journal_title：Pediatric transplantation

authors： Mizuiri S,Shigetomi Y,Sugiyama K,Miyagi M,Hatano T,Tajima E,Aikawa A,Ohara T,Kawamura S,Hasegawa A

更新日期：2000-02-01 00:00:00

abstract：:With the number of long-term HSCT survivors steadily increasing, attention needs to be focused on the late complications and quality of life. We therefore analyzed the outcome of 101 pediatric patients (<18 years old at the time of HSCT) transplanted for acute leukemia between 1981 and 2015 at Complexo Hospital de Clí...

journal_title：Pediatric transplantation

authors： Marinho DH,Ribeiro LL,Nichele S,Loth G,Koliski A,Mousquer RTG,Funke VAM,Page K,Fasth A,Pasquini R,Boguszewski MCDS,Bonfim C

更新日期：2020-06-01 00:00:00

abstract：:The purpose of this study was to assess the inter-rater reliability of the P-TRI, a 17-item instrument developed to identify risk factors associated with poor treatment adherence in pediatric solid organ transplant candidates. Because factors influencing treatment adherence may vary with age, the 89 subject samples we...

journal_title：Pediatric transplantation

authors： Fisher M,Storfer-Isser A,Shaw RJ,Bernard RS,Drury S,Ularntinon S,Horwitz SM

更新日期：2011-03-01 00:00:00

abstract：:ADV is frequently seen in our pediatric SOT population. It presents in a variety of clinical presentation and can cause severe disease. In this population, there are very few studies to determine the safety of CDV as a potential therapeutic agent. We present the findings of our retrospective study evaluating the effic...

journal_title：Pediatric transplantation

authors： Guerra Sanchez CH,Lorica CD,Arheart KL,Perez MM,Tekin A,Gonzalez IA

更新日期：2018-06-03 00:00:00

abstract：:A five-yr-old boy developed chronic liver failure and ESKD because of CHF and juvenile NPHP. He underwent sequential liver and kidney transplantation with a compatible blood type from his father, at five yr, seven months and five yr, 11 months old, respectively. Because the patient was not in ESKD, we initially perfor...

journal_title：Pediatric transplantation

authors： Udagawa T,Kamei K,Ogura M,Tsutsumi A,Noda S,Kasahara M,Fukuda A,Sakamoto S,Shigeta S,Tanaka H,Kuroda T,Matsuoka K,Nakazawa A,Nagai T,Uemura O,Ito S

更新日期：2012-11-01 00:00:00

abstract：:A 4-year-old boy presented 14 months after liver and small bowel transplantation with fever, diarrhea, elevated liver enzymes, thrombocytopenia and autoantibodies. Total gammaglobulins level was normal but the level of plasma IgA1 was very high. The blood PCR for Epstein-Barr virus (EBV) was negative. The ileal biopsy...

journal_title：Pediatric transplantation

authors： Robert CD,Lacaille F,Canioni D,Quartier-dit-Maire P,Talbotec C,Goulet O

更新日期：2004-06-01 00:00:00

abstract：:Cardiac transplantation for children with end-stage cardiac disease with no other medical or surgical options is now standard. The number of children in need of cardiac transplant continues to exceed the number of donors considered "acceptable." Therefore, there is an urgent need to understand which recipients are in ...

journal_title：Pediatric transplantation

authors： Denfield SW,Azeka E,Das B,Garcia-Guereta L,Irving C,Kemna M,Reinhardt Z,Thul J,Dipchand AI,Kirk R,Davies RR,Miera O

更新日期：2020-05-01 00:00:00

abstract：:Children undergoing liver transplantation are at a significant risk for intraoperative hemorrhage and thrombotic complications, we aim to identify novel risk factors for massive intraoperative blood loss and transfusion in PLT recipients and describe its impact on graft survival and hospital LOS. We reviewed all prima...

journal_title：Pediatric transplantation

authors： Villarreal JA,Yoeli D,Ackah RL,Sigireddi RR,Yoeli JK,Kueht ML,Galvan NTN,Cotton RT,Rana A,O'Mahony CA,Goss JA

更新日期：2019-06-01 00:00:00

abstract：:CNL is a rare myeloproliferative disorder frequently seen in older adults. A significant proportion of patients show progression to AML. Here, we report the case of a patient with FA who was monitored for leukopenia but who developed leukocytosis during the follow-up and was diagnosed with CNL probably after an acquir...

journal_title：Pediatric transplantation

authors： Uygun V,Daloğlu H,Öztürkmen S,Karasu G,Avcı Z,Yeşilipek A

更新日期：2018-08-01 00:00:00

abstract：:BM remains an important source of stem cells. The BM characteristics change with age but the estimation of CD34 calculation of one CD34+ cell per 100 nucleated cells is used for all donors including pediatric donors in the operating room before getting the actual CD34 count. In order to see whether this formula is app...

journal_title：Pediatric transplantation

authors： Ince EU,Ileri T,Dogu F,Ates C,Cakmakli H,Dalva K,Ikinciogullari A,Uysal Z,Ertem M

更新日期：2015-06-01 00:00:00

abstract：:A major risk faced by bone-marrow and solid organ transplant patients is the development of post-transplant lymphoproliferative disease or post-transplant lymphoma (PTLD). In pediatric transplantation, PTLD onset is often associated with a rapid rise in Epstein-Barr virus (EBV) load in peripheral blood mononuclear cel...

journal_title：Pediatric transplantation

authors： Orentas RJ,Schauer DW Jr,Ellis FW,Walczak J,Casper JT,Margolis DA

更新日期：2003-08-01 00:00:00

abstract：:In their provocative paper, "Lung transplantation and survival in children with cystic fibrosis," Liou and colleagues state that "Prolongation of life by means of lung transplantation should not be expected in children with cystic fibrosis. A prospective, randomized trial is needed to clarify whether and when patients...

journal_title：Pediatric transplantation

authors： Sweet SC,Aurora P,Benden C,Wong JY,Goldfarb SB,Elidemir O,Woo MS,Mallory GB Jr,International Pediatric Lung Transplant Collaborative.

更新日期：2008-03-01 00:00:00